Conservación del patrimonio cultural utilizando nuevos métodos de comunicación: la Pagoda de madera de Yingxian, China

[EN] Architectural landmarks that represent a culture’s identity are also sanctuaries for cultural heritage preservation. The tallest and oldest wooden multi-story structure in the world, the Yingxian Wooden Pagoda of China is tilting at an ongoing rate that requires an urgency to find solutions to revert the damage. To preserve the evolving humanistic and artistic understandings of ancient Chinese architecture, and to cultivate the scientific reasoning behind ancient Chinese carpentry, new media allows digital and computational methods to replace human users who once manually analyzed data and information from cultural sites and artifacts. This article will exemplify new media tools such as animation via 3D/2D modeling, 3D scanning and virtual reality photography to examine material evidence of the Yingxian Wooden Pagoda of China, and the role new media can assist in its fight to sustain its originality since 1056.Highlights: Examination, documentation, research and education of architectural heritage sites using new media methods.Integration of old archives and digital/computational software to represent the outstanding value of the oldest and tallest wooden skyscraper in the world.Use of 2D/3D modelling and virtual reality photography developing information to increase awareness on cultural heritage sites suffering wood deterioration.[ES] Los hitos arquitectónicos que representan la identidad de una cultura también son santuarios para la preservación del patrimonio cultural. La pagoda de madera de Yingxian en China, la estructura de madera de varios pisos más alta y antigua del mundo, se inclina a un ritmo constante que requiere encontrar solución es urgentes que reviertan el daño. Para preservar la evolución humanística y la comprensión artística de la antigua arquitectura china, y para cultivar el razonamiento científico detrás de la antigua carpintería china, los nuevos medios de comunicación permiten asistencia digital y computacional a los usuarios humanos que analizaban manualmente los datos y la información de los sitios culturales y los artefactos. La evidencia alcanzada a partir de las investigaciones previas unido a que los métodos de documentación clásicos requerían una comprensión sólida de la información realizada por el investigador, conlleva a que los registros se puedan describir como estáticos y anticuados, y que solo pueden ofrecer información tal y como se presenta. Los nuevos medios de comunicación ofrecen a la Pagoda de madera de Yingxian la última asistencia digital para encontrar descubrimientos que no eran posibles de llevar a cabo en investigaciones anteriores usando los métodos clásicos. La ayuda de programas y herramientas computacionales amplía la evidencia ocultada en los sitios patrimoniales. Este artículo ejemplificará las nuevas herramientas de comunicación, como la animación a través del modelado 3D/2D, el escaneado 3D y la fotografía de realidad virtual para examinar la evidencia material de la Pagoda de madera de Yingxian, y el papel que los nuevos medios pueden desempeñar en su lucha por mantener la originalidad de esta pagoda budista de madera desde 1056.Lai, DS.; Leung, AK.; Chan, D.; Ching, SH. (2019). Cultural heritage preservation using new media methods: Yingxian Wooden Pagoda, China. Virtual Archaeology Review. 10(21):103-115. https://doi.org/10.4995/var.2019.11071SWORD1031151021ACRL, (2015, February 9). Framework for Information Literacy for Higher Education. American Library Association. (p. 7-8)Ching, H.S. (2018, March). Turning a Service Learning Experience into a Model of Student Engagement: The Lighthouse Heritage Research Connections (LHRC) Project in Hong Kong. Elsevier BV: The Journal of Academic Librarianship, ISSN: 0099-1333, Vol: 44, Issue: 2, (p. 196-206).Eggers, R. (2017, January 9). Virtual Reality: The Future of Photography?. Retrieved from http://www.direporter.com/products/360o/virtual-reality-future-photography.Heidegger, M. (1971). 'The Thing'. In Poetry, Language, Thought, translated by A. Hofstafter. New York: Harper & Row.Hernandez, M. (2018, June 11). The Dougong: A nailless Chinese construction method. Retrieved from https://multimedia.scmp.com/culture/article/forbidden-city/architecture/chapter_02.html. South China Morning Post.Hou, W.D (侯卫东). (2016). Ying Xian Mu Ta Bao Hu Yan Jiu (应县木塔保护研究). Beijing, China: Beijing Shi : Wen Wu Chu Ban She (文物出版社).Jia, D.Y. (2015). Principles for the Conservation Heritage Sites in China. Beijing, China: Beijing Shi : Wen Wu Chu Ban She (文物出版社). (p. 100).Lai, D. (2018). (Director). The Preservation of the Yingxian Wooden Pagoda. Hong Kong: City University of Hong Kong. Retrieved from https://www.cityu.edu.hk/cityvod/video/play/LIB/Yingxian_Pagoda.aspxLeary, C. (n.d.). 360 VR Panoramic Photography. Retrieved from http://chrisleary.photography/360-vr-panoramic-photography/Manovich, L. (2001) The language of new media. Cambridge, Mass: MIT Press. (p. 36)Malpas, J. (2008) New Media. Cultural Heritage and the Sense of Place: Mapping the Conceptual Ground. International Journal of Heritage Studies. (p. 198)NOAA. (2018). Significant Earthquake Search - sorted by Data. Retrieved from https://www.ngdc.noaa.gov/nndc/struts/results?bt_0=1056&st_0=2018&type_17=EXACT&query_17=30&op_12=eq&v_12=CHINA&type_12=Or&query_14=None%20Selected&type_3=Like&query_3=Shanxi&st_1=&bt_2=&st_2=&bt_1=&bt_4=&st_4=&bt_5=&st_5=&bt_6=&st_6=&bt_7=&st_7=&bt_8=&st_8=&bt_9=&st_9=&bt_10=&st_10=&type_11=Exact&query_11=&type_16=Exact&query_16=&bt_18=&st_18=&ge_19=&le_19=&type_20=Like&query_20=&display_look=1&t=101650&s=1&submit_all=Search%20Database. National Centers for Environmental Information.Thompson, R.M. (2017). Firearm Identification in the Forensic Science Laboratory. 10.13140/RG.2.2.16250.59846. (p.7)Tian, W., Wang Y.R., 山西省应县县志办公室. (1984). 应州志. China: 山西省应县县志办公室重印.Tollefson, J. (2017, May 17). The wooden skyscrapers that could help to cool the planet. Retrieved from https://www.nature.com/news/the-wooden-skyscrapers-that-could-help-to-cool-the-planet-1.21992UNESCO World Heritage Centre. (2013). Wooden Structures of Liao Dynasty-Wooden Pagoda of Yingxian County, Main Hall of Fengguo Monastery of Yixian County. Retrieved from https://whc.unesco.org/en/tentativelists/5803

Mechanism of efficient anti-Markovnikov olefin hydroarylation catalyzed by homogeneous Ir(III) complexes

The mechanism of the hydroarylation reaction between unactivated olefins (ethylene, propylene, and styrene) and benzene catalyzed by [(R)Ir(μ-acac-O,O,C^3)-(acac-O,O)_2]_2 and [R-Ir(acac-O,O)_2(L)] (R = acetylacetonato, CH_3, CH_2CH_3, Ph, or CH_2CH_2Ph, and L = H_2O or pyridine) Ir(III) complexes was studied by experimental methods. The system is selective for generating the anti-Markovnikov product of linear alkylarenes (61 : 39 for benzene + propylene and 98 : 2 for benzene + styrene). The reaction mechanism was found to follow a rate law with first-order dependence on benzene and catalyst, but a non-linear dependence on olefin. ^(13)C-labelling studies with CH_3^(13)CH_2-Ir-Py showed that reversible β-hydride elimination is facile, but unproductive, giving exclusively saturated alkylarene products. The migration of the ^(13)C-label from the α to β-positions was found to be slower than the C–H activation of benzene (and thus formation of ethane and Ph-d_5-Ir-Py). Kinetic analysis under steady state conditions gave a ratio of the rate constants for CH activation and β-hydride elimination (k_(CH): k_β) of 0.5. The comparable magnitude of these rates suggests a common rate determining transition state/intermediate, which has been shown previously with B3LYP density functional theory (DFT) calculations. Overall, the mechanism of hydroarylation proceeds through a series of pre-equilibrium dissociative steps involving rupture of the dinuclear species or the loss of L from Ph-Ir-L to the solvento, 16-electron species, Ph-Ir(acac-O,O)_2-Sol (where Sol refers to coordinated solvent). This species then undergoes trans to cis isomerization of the acetylacetonato ligand to yield the pseudo octahedral species cis-Ph-Ir-Sol, which is followed by olefin insertion (the regioselective and rate determining step), and then activation of the C–H bond of an incoming benzene to generate the product and regenerate the catalyst

Physical activity for cancer survivors: meta-analysis of randomised controlled trials

Objective To systematically evaluate the effects of physical activity in adult patients after completion of main treatment related to cancer

Generalized Flow and Determinism in Measurement-based Quantum Computation

We extend the notion of quantum information flow defined by Danos and Kashefi for the one-way model and present a necessary and sufficient condition for the deterministic computation in this model. The generalized flow also applied in the extended model with measurements in the X-Y, X-Z and Y-Z planes. We apply both measurement calculus and the stabiliser formalism to derive our main theorem which for the first time gives a full characterization of the deterministic computation in the one-way model. We present several examples to show how our result improves over the traditional notion of flow, such as geometries (entanglement graph with input and output) with no flow but having generalized flow and we discuss how they lead to an optimal implementation of the unitaries. More importantly one can also obtain a better quantum computation depth with the generalized flow rather than with flow. We believe our characterization result is particularly essential for the study of the algorithms and complexity in the one-way model.Comment: 16 pages, 10 figure

Generalized Flow and Determinism in Measurement-based Quantum Computation

We extend the notion of quantum information flow defined by Danos and Kashefi for the one-way model and present a necessary and sufficient condition for the deterministic computation in this model. The generalized flow also applied in the extended model with measurements in the X-Y, X-Z and Y-Z planes. We apply both measurement calculus and the stabiliser formalism to derive our main theorem which for the first time gives a full characterization of the deterministic computation in the one-way model. We present several examples to show how our result improves over the traditional notion of flow, such as geometries (entanglement graph with input and output) with no flow but having generalized flow and we discuss how they lead to an optimal implementation of the unitaries. More importantly one can also obtain a better quantum computation depth with the generalized flow rather than with flow. We believe our characterization result is particularly essential for the study of the algorithms and complexity in the one-way model.Comment: 16 pages, 10 figure

Defining criteria for rheumatoid arthritis patient-derived disease activity score that correspond to Disease Activity Score 28 and Clinical Disease Activity Index based disease states and response criteria

Objective. Two versions of a patient-based DAS (PDAS) 1 and 2 (with and without ESR) have been developed and validated in RA. The objective of this study was to define PDAS1- and PDAS2-based criteria for remission, low, moderate and high disease activity and responses to treatment. Method. Using receiver operating characteristic curves, the optimal thresholds for PDAS1 and PDAS2 that correspond to validated assessor-based DAS (DAS28) and Clinical Disease Activity Index (CDAI) disease statuses were determined. Data from RA patients initiated on disease-modifying drugs were used to determine optimal thresholds for PDAS1 and PDAS2 that corresponded to EULAR good and moderate responses. Agreement with DAS28, CDAI and EULAR response criteria was assessed by Cohen’s κ statistic. Results. Threshold for PDAS1 and PDAS2 demonstrated fair to moderate agreement with DAS28 [κ = 0.44 (95% CI: 0.40, 0.50) and 0.31 (95% CI: 0.25, 0.38)] and CDAI [κ = 0.27 (95% CI: 0.22, 0.33) and 0.42 (95% CI: 0.35, 0.49)] disease statuses, respectively, which was similar to agreement between DAS28 and CDAI [κ = 0.54 (95% CI: 0.46, 0.61)] within this group. Agreement of EULAR good and moderate response with PDAS1 and PDAS2 was κ = 0.46 (95% CI: 0.27, 0.64) and 0.38 (95% CI: 0.20, 0.56), respectively. Conclusion. Thresholds for disease activity statuses and response to treatment for PDAS1 and PDAS2 have been established. They have comparable agreement to assessor-based criteria

Variceal Hemorrhage and Adverse Liver Outcomes in Patients With Cystic Fibrosis Cirrhosis

OBJECTIVES: Cirrhosis occurs in 5% to 10% of cystic fibrosis (CF) patients, often accompanied by portal hypertension. We analyzed 3 adverse liver outcomes, variceal bleeding (VB), liver transplant (LT), and liver-related death (LD), and risk factors for these in CF Foundation Patient Registry subjects with reported cirrhosis. METHODS: We determined 10-year incidence rates for VB, LT, LD, and all-cause mortality (ACM), and examined risk factors using competing risk models and Cox-proportional hazard regression. RESULTS: From 2003 to 2012, 943 participants (41% females, mean age 18.1 years) had newly reported cirrhosis; 24.7% required insulin, 85% had previous pseudomonas. Seventy-three subjects had reported VB: 38 with first VB and new cirrhosis reported simultaneously and 35 with VB after cirrhosis report. Ten-year cumulative VB, LT, and LD rates were 6.6% (95% confidence interval [CI]: 4.0, 9.1%), 9.9% (95% CI: 6.6%, 13.2%), and 6.9% (95% CI: 4.0%, 9.8%), respectively, with an ACM of 39.2% (95% CI: 30.8, 36.6%). ACM was not increased in subjects with VB compared to those without (hazard ratio [HR] 1.10, 95% CI: 0.59, 2.08). CF-related diabetes (HR: 3.141, 95% CI:1.56, 6.34) and VB (HR: 4.837, 95% CI: 2.33, 10.0) were associated with higher LT risk, whereas only worse lung function was associated with increased LD in multivariate analysis. Death rate among subjects with VB was 24% with LT and 20.4% with native liver. CONCLUSIONS: VB is an uncommon complication of CF cirrhosis and can herald the diagnosis, but does not affect ACM. Adverse liver outcomes and ACM are frequent by 10 years after cirrhosis report

Brokered Graph State Quantum Computing

We describe a procedure for graph state quantum computing that is tailored to fully exploit the physics of optically active multi-level systems. Leveraging ideas from the literature on distributed computation together with the recent work on probabilistic cluster state synthesis, our model assigns to each physical system two logical qubits: the broker and the client. Groups of brokers negotiate new graph state fragments via a probabilistic optical protocol. Completed fragments are mapped from broker to clients via a simple state transition and measurement. The clients, whose role is to store the nascent graph state long term, remain entirely insulated from failures during the brokerage. We describe an implementation in terms of NV-centres in diamond, where brokers and clients are very naturally embodied as electron and nuclear spins.Comment: 5 pages, 3 figure

Swine ANP32A supports avian influenza virus polymerase

Avian influenza viruses occasionally infect and adapt to mammals, including humans. Swine are often described as 'mixing vessels', being susceptible to both avian and human origin viruses, which allows the emergence of novel reassortants, such as the precursor to the 2009 H1N1 pandemic. ANP32 proteins are host factors that act as influenza virus polymerase cofactors. In this study we describe how swine ANP32A, uniquely among the mammalian ANP32 proteins tested, supports activity of avian origin influenza virus polymerases, and avian influenza virus replication. We further show that after the swine-origin influenza virus emerged in humans and caused the 2009 pandemic it evolved polymerase gene mutations that enabled it to more efficiently use human ANP32 proteins. We map the enhanced pro-viral activity of swine ANP32A to a pair of amino acids, 106 and 156, in the leucine-rich repeat and central domains and show these mutations enhance binding to influenza virus trimeric polymerase. These findings help elucidate the molecular basis for the 'mixing vessel' trait of swine and further our understanding of the evolution and ecology of viruses in this host.Importance Avian influenza viruses can jump from wild birds and poultry into mammalian species such as humans or swine, but only continue to transmit if they accumulate mammalian adapting mutations. Pigs appear uniquely susceptible to both avian and human strains of influenza and are often described as virus 'mixing vessels'. In this study, we describe how a host factor responsible for regulating virus replication, ANP32A, is different between swine and humans. Swine ANP32A allows a greater range of influenza viruses, specifically those from birds, to replicate. It does this through binding the virus polymerase more tightly than the human version of the protein. This work helps to explain the unique properties of swine as 'mixing vessels'

Psychometric evaluation of the Hospital Anxiety and Depression Scale in a large community sample of adolescents in Hong Kong

Purpose: The Hospital Anxiety and Depression Scale (HADS) is widely used in adult populations; however, its usefulness with adolescents has been explored less. This study sought to evaluate the reliability, validity, and factor structure of the Chinese version of HADS in a community sample of adolescents residing in Hong Kong. Methods: A prospective cohort of 5,857 students recruited from 17 secondary schools completed the HADS. Internal consistency and concurrent validity were examined. Confirmatory factor analysis was applied to test the relative fits of six factor structures of the HADS. The best fitting model was further cross-validated by male, female, splithalf samples, and age subgroups. Results: The HADS possessed adequate internal consistency, especially for the anxiety subscale. Significant concurrent intercorrelations with self-reported suicidal thoughts and the Youth Self Report Anxious/Depressed subscale were discovered and found to be stronger for females. The cross-validation supported a two-factor model, where anxiety item 7, "I can sit at ease and feel relaxed", was placed in the depression subscale. Conclusions: The HADS showed satisfactory psychometric properties as a screening instrument in assessing anxious and depressive states as two correlated but distinct factors in adolescents. Study implications and recommendations for future research were discussed.published_or_final_versionSpringer Open Choice, 21 Feb 201