Monotonicity of Social Optima With Respect to Participation Constraints.

In this paper we consider solutions which select from the core. For games with side payments with at least four players, it is well-known that no core-selection satifies monotonicity for all coalitions; for the particular class of core-selections found by maximizing a social welfare function over the core, we investigate whether such solutions are monotone for a given coalition. It is shown that if this is the case then the solution actually maximizes aggregate coalition payoff on the core. Furthermore, the social welfare function to be maximized exhibits larger marginal social welfare with respect to the payoff of any member of the coalition. The results may be used to show that there are no monotonic core selection rules of this type in the context of games without side payments.coalitional games; monotonicity; core; social welfare

Behavioral public performance: making effective use of metrics about government activity

Oliver James, Donald Moynihan, Asmus Olsen and Gregg van Ryzin discuss how insights from behavioural science show the way managers, politicians and citizens make sense of, and act on, information about government performance

Potential of the Cone Pressuremeter Test for obtaining stiffness degradation for offshore wind turbine monopile foundations

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Differential expression of collectins in human placenta and role in inflammation during spontaneous Labor.

© 2014 Yadav et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Collectins, collagen-containing Ca2+ dependent C-type lectins and a class of secretory proteins including SP-A, SP-D and MBL, are integral to immunomodulation and innate immune defense. In the present study, we aimed to investigate their placental transcript synthesis, labor associated differential expression and localization at feto-maternal interface, and their functional implication in spontaneous labor. The study involved using feto-maternal interface (placental/decidual tissues) from two groups of healthy pregnant women at term (≥37 weeks of gestation), undergoing either elective C-section with no labor ('NLc' group, n = 5), or normal vaginal delivery with spontaneous labor ('SLv' group, n = 5). The immune function of SP-D, on term placental explants, was analyzed for cytokine profile using multiplexed cytokine array. SP-A, SP-D and MBL transcripts were observed in the term placenta. The 'SLv' group showed significant up-regulation of SP-D (p = 0.001), and down-regulation of SP-A (p = 0.005), transcripts and protein compared to the 'NLc' group. Significant increase in 43 kDa and 50 kDa SP-D forms in placental and decidual tissues was associated with the spontaneous labor (p<0.05). In addition, the MMP-9-cleaved form of SP-D (25 kDa) was significantly higher in the placentae of 'SLv' group compared to the 'NLc' group (p = 0.002). Labor associated cytokines IL-1α, IL-1β, IL-6, IL-8, IL-10, TNF-α and MCP-1 showed significant increase (p<0.05) in a dose dependent manner in the placental explants treated with nSP-D and rhSP-D. In conclusion, the study emphasizes that SP-A and SP-D proteins associate with the spontaneous labor and SP-D plausibly contributes to the pro-inflammatory immune milieu of feto-maternal tissues.Funding provided by BT/PR15227/BRB/10/906/2011) Department of Biotechnology (DBT), Government of India http://dbtindia.nic.in/index.asp (TM) and Indian Council of Medical Research (ICMR) Junior Research Fellowship (JRF)/Senior Research Fellowship (SRF), Government of India, www.icmr.nic.in (AKY)