Galactic Cosmic Rays Modulation in the Vicinity of Corotating Interaction Regions: Observations During the Last Two Solar Minima

Corotating interaction regions (CIRs) are responsible for short-term recurrent cosmic-ray modulation, prominent near solar minima. Using the OMNI data sets for two periods of low solar activity near the beginning and end of solar cycle 24, superposed epoch analysis was performed on the solar wind plasma features for 53 and 43 events during periods 2007–2008 and 2017–2018, respectively. Turbulent properties of the solar wind were studied using the variance method for each CIR. Power spectra have been constructed for overlapped subintervals in the vicinity of stream interfaces (SIs). Using measured correlation lengths and turbulent energies, parallel and perpendicular diffusion mean free paths for cosmic-ray ions have been inferred based on two distinct theoretical formulations. For the two periods with opposite solar polarities, our results show that unlike solar wind speed, magnetic field strength, flow pressure, and proton density are relatively higher during the latest period. Increased turbulent energy and reduced parallel transport coefficients of energetic particles at the SIs are observed. The diffusion coefficients follow the same trends during both periods. The perpendicular diffusion starts increasing nearly a day before SIs and is higher in the fast wind. Superposed epoch analysis is performed on the >120 MeV proton count rate obtained from the CRIS instrument on board the ACE spacecraft for the same events. The recorded proton rates have peaks half a day before a SI and reach their minimum more than a day after a SI and have a high anticorrelation with the perpendicular diffusion coefficient

STEREO Observations of Solar Energetic Particles

We report on observations of Solar Energetic Particle (SEP) events as observed by instruments on the STEREO Ahead and Behind spacecraft and on the ACE spacecraft. We will show observations of an electron event observed by the STEREO Ahead spacecraft on June 12, 2010 located at W74 essentially simultaneously with electrons seen at STEREO Behind at E70. Some similar events observed by Helios were ascribed to fast electron propagation in longitude close to the sun. We will look for independent verification of this possibility. We will also show observations of what appears to be a single proton event with very similar time-history profiles at both of the STEREO spacecraft at a similar wide separation. This is unexpected. We will attempt to understand all of these events in terms of corresponding CME and radio burst observations

Galactic Cosmic Rays Modulation in the Vicinity of Corotating Interaction Regions: Observations During the Last Two Solar Minima

Corotating interaction regions (CIRs) are responsible for short-term recurrent cosmic-ray modulation, prominent near solar minima. Using the OMNI data sets for two periods of low solar activity near the beginning and end of solar cycle 24, superposed epoch analysis was performed on the solar wind plasma features for 53 and 43 events during periods 2007–2008 and 2017–2018, respectively. Turbulent properties of the solar wind were studied using the variance method for each CIR. Power spectra have been constructed for overlapped subintervals in the vicinity of stream interfaces (SIs). Using measured correlation lengths and turbulent energies, parallel and perpendicular diffusion mean free paths for cosmic-ray ions have been inferred based on two distinct theoretical formulations. For the two periods with opposite solar polarities, our results show that unlike solar wind speed, magnetic field strength, flow pressure, and proton density are relatively higher during the latest period. Increased turbulent energy and reduced parallel transport coefficients of energetic particles at the SIs are observed. The diffusion coefficients follow the same trends during both periods. The perpendicular diffusion starts increasing nearly a day before SIs and is higher in the fast wind. Superposed epoch analysis is performed on the >120 MeV proton count rate obtained from the CRIS instrument on board the ACE spacecraft for the same events. The recorded proton rates have peaks half a day before a SI and reach their minimum more than a day after a SI and have a high anticorrelation with the perpendicular diffusion coefficient

Characterization Of Large-Area Silicon Ionization Detectors For The ACE Mission

We report on extensive tests of large-area (10 cm diameter) high-purity ion-implanted silicon detectors for the solar isotope spectrometer (SIS), and lithium-drifted silicon detectors for the cosmic ray isotope spectrometer (CRIS), which are under development for launch on the advanced composition explorer (ACE) mission. Depletion and breakdown characteristics versus bias were studied, as were long-term current and noise stability in a thermally cycled vacuum. Dead-layer and total thickness maps were obtained using laser interferometry, beams of energetic argon nuclei and radioactive sources of alpha particles. Results, selection criteria, and yields are presented

Two-Dimensional Position-Sensitive Silicon Detectors For The ACE Solar Isotope Spectrometer

Two-dimensional position-sensitive silicon detectors ('matrix detectors') have been designed, procured, and tested as part of the development of the solar isotope spectrometer (SIS) instrument for NASA's Advanced Composition Explorer (ACE) mission. Important characteristics of these devices include: thickness approximately 50 - 90 micrometer, active area 34 cm^2, 64 strips on each surface with 1 mm strip pitch. The SIS instrument uses four such detectors, processing signals from each of the 512 individual strips with a separate 12-bit pulse height analyzer implemented with custom-designed VLSI circuits. A set of 25 matrix detectors have been characterized through a variety of tests intended both toe select the best candidates for use in the flight instrument and to provide the calibrations needed to interpret flight data. We discuss the design of the SIS matrix detectors and present selected results from the detector tests that have been performed

Latanoprost for open-angle glaucoma (UKGTS): a randomised, multicentre, placebo-controlled trial

Background: Treatments for open-angle glaucoma aim to prevent vision loss through lowering of intraocular pressure, but to our knowledge no placebo-controlled trials have assessed visual function preservation, and the observation periods of previous (unmasked) trials have typically been at least 5 years. We assessed vision preservation in patients given latanoprost compared with those given placebo. Methods: In this randomised, triple-masked, placebo-controlled trial, we enrolled patients with newly diagnosed open-angle glaucoma at ten UK centres (tertiary referral centres, teaching hospitals, and district general hospitals). Eligible patients were randomly allocated (1:1) with a website-generated randomisation schedule, stratified by centre and with a permuted block design, to receive either latanoprost 0·005% (intervention group) or placebo (control group) eye drops. Drops were administered from identical bottles, once a day, to both eyes. The primary outcome was time to visual field deterioration within 24 months. Analyses were done in all individuals with follow-up data. The Data and Safety Monitoring Committee (DSMC) recommended stopping the trial on Jan 6, 2011 (last patient visit July, 2011), after an interim analysis, and suggested a change in primary outcome from the difference in proportions of patients with incident progression between groups to time to visual field deterioration within 24 months. This trial is registered, number ISRCTN96423140. Findings: We enrolled 516 individuals between Dec 1, 2006, and March 16, 2010. Baseline mean intraocular pressure was 19·6 mm Hg (SD 4·6) in 258 patients in the latanoprost group and 20·1 mm Hg (4·8) in 258 controls. At 24 months, mean reduction in intraocular pressure was 3·8 mm Hg (4·0) in 231 patients assessed in the latanoprost group and 0·9 mm Hg (3·8) in 230 patients assessed in the placebo group. Visual field preservation was significantly longer in the latanoprost group than in the placebo group: adjusted hazard ratio (HR) 0·44 (95% CI 0·28–0·69; p=0·0003). We noted 18 serious adverse events, none attributable to the study drug. Interpretation: This is the first randomised placebo-controlled trial to show preservation of the visual field with an intraocular-pressure-lowering drug in patients with open-angle glaucoma. The study design enabled significant differences in vision to be assessed in a relatively short observation period

Reflections on Seminole Rock: The Past, Present, and Future of Deference to Agency Regulatory Interpretations

Seminole Rock (or Auer) deference has captured the attention of scholars, policymakers, and the judiciary. That is why Notice & Comment, the blog of the Yale Journal on Regulation and the American Bar Association’s Section of Administrative Law & Regulatory Practice, hosted an online symposium from September 12 to September 23, 2016 on the subject. This symposium contains over 20 contributions addressing different aspects of Seminole Rock deference. Topics include: History of Seminole Rock Empirical Examinations of Seminole Rock Understanding Seminole Rock Within Agencies Understanding Seminole Rock as Applied to Tax, Environmental Law, and Criminal Sentencing Why Seminole Rock Matters Should the Supreme Court Overrule Seminole Rock? Would Overruling Seminole Rock Have Unintended Consequences? What Might the Supreme Court Do? What Might Congress Do? The Future of Seminole Roc