Status of contaminated marine sediments in four Nordic countries : assessments, regulations, and remediation approaches

Purpose Since the 1960s, pollution of the marine environment has been observed around the world, and a general awareness of the potential environmental hazards from contaminants arose. This general awareness was followed by implementation of environmental regulations at the national and international levels regarding industrial discharges, and forcing the development of management programs to improve the environmental quality. This overview focuses on the status of assessments, regulations, and remediation actions of contaminated marine sediments in four North European countries: Sweden, Norway, Finland, and Denmark. Results and discussion We found that the extent of assessment surveys and the implementation of sediment remediation actions vary between the countries, with Norway the most advanced. Norway has initiated national pilot remediation tests, followed by full-scale site remediation by dredging and in situ capping in several projects along the coast. Sweden is following Norway's example, although with fewer completed projects. In Finland, the tradition of maintenance dredging is still very strong although the main purpose has not been cleanup actions. Accordingly, in Denmark, dredging is primarily used to maintain sailing depths. All four countries have implemented the Water Framework Directive in addition to national regulations that provide the authority for imposing and implementing sediment remediation measures. However, only Norway has implemented a national strategy on remediation of contaminated sediments. Conclusions This overview highlights the need for enhanced communication and exchange of experiences between the four Nordic countries of concern with regard to sediment remediation strategy and management

Aqueous uptake and sublethal toxicity of p,p′-DDE in non-feeding larval stages of Antarctic krill (Euphausia superba)

This study evaluated the toxicological sensitivity of non-feeding larval stages of a key Antarctic species (Antarctic krill, Euphausia superba) to p,p′-dichlorodiphenyl dichloroethylene (p,p′-DDE) exposure. The aqueous uptake clearance rate of 84 mL g preserved weight (p.w.) h determined for p,p′-DDE in Antarctic krill larvae is comparable to previous findings for small cold water crustaceans and five times slower than the rates reported for an amphipod inhabiting warmer waters. Natural variations in larval physiology appear to influence contaminant uptake and larval krill behavioural responses, strongly highlighting the importance of time of measurement for ecotoxicological testing. Sublethal narcosis (immobility) was observed in larval Antarctic krill from p,p′-DDE body residues of 0.2 mmol/kg p.w., which is in agreement with findings for adult krill and temperate aquatic species. The finding of comparable body residue-based toxicity of p,p′-DDE between polar and temperate species supports the tissue residue approach for environmental risk assessment of polar ecosystems

Heme oxygenase-1 repeat polymorphism in septic acute kidney injury

Abstract Acute kidney injury (AKI) is a syndrome that frequently affects the critically ill. Recently, an increased number of dinucleotide repeats in the HMOX1 gene were reported to associate with development of AKI in cardiac surgery. We aimed to test the replicability of this finding in a Finnish cohort of critically ill septic patients. This multicenter study was part of the national FINNAKI study. We genotyped 300 patients with severe AKI (KDIGO 2 or 3) and 353 controls without AKI (KDIGO 0) for the guanine–thymine (GTn) repeat in the promoter region of the HMOX1 gene. The allele calling was based on the number of repeats, the cut off being 27 repeats in the S–L (short to long) classification, and 27 and 34 repeats for the S–M–L₂ (short to medium to very long) classification. The plasma concentrations of heme oxygenase-1 (HO-1) enzyme were measured on admission. The allele distribution in our patients was similar to that published previously, with peaks at 23 and 30 repeats. The S-allele increases AKI risk. An adjusted OR was 1.30 for each S-allele in an additive genetic model (95% CI 1.01–1.66; p = 0.041). Alleles with a repeat number greater than 34 were significantly associated with lower HO-1 concentration (p<0.001). In septic patients, we report an association between a short repeat in HMOX1 and AKI risk