Souped Up Affirmative Disclosure Orders of the Federal Trade Commission

Under section 5(b) of the Federal Trade Commission Act the Commission is given authority to conduct hearings, make findings and issue cease and desist orders requiring any person, partnership or corporation to cease and desist from use of unfair methods of competition or unfair or deceptive practices in commerce. The Commission also issues consent orders in cases which are concluded by agreement between the Commission and the allegedly offending party. Consent orders have the same force and binding effect as those issued after hearings and findings. Although it is well established that the Commission has very broad discretion and authority in framing the scope of its orders, there are limits on its power. It is the thesis of this paper that the Federal Trade Commission has exceeded its broad authority to fashion cease and desist orders in its recent proposal to include in some cease and desist orders a requirement that the respondents against whom the orders are issued must disclose in their subsequent advertising that a cease and desist order is standing against them because of claims they made in prior advertising. One of these is Standard Oil Company of California, where the Federal Trade Commission has issued a complaint challenging certain advertising claims made by Standard for its Chevron brand gasoline. The gasoline has an additive known as F-310, which is claimed by Standard to have significant effect in reducing the amount of unburned hydrocarbons and carbon monoxide emissions in automotive exhaust fumes, thereby contributing to the reduction of air pollution. The Commission has challenged the F-310 claims as unfounded and deceptive. It has proposed a cease and desist order which, in addition to requiring Standard to cease and desist from use of the allegedly misleading F-310 claims, would require it to disclose in all gasoline advertisements, for the period of one year, that former advertising for its gasoline had contained false, misleading and deceptive statements, representations and demonstrations. The Commission would require that not less than twenty-five percent of the space or exposure time devoted to each subsequent advertisement be used for the purpose of making the affirmative disclosure. The other case involves the Coca-Cola Company\u27s advertising for Hi-C fruit drinks, where similar affirmative disclosure requirements are proposed by the Commission. The proposed cease and desist order would bar Coca-Cola from making nutrient claims for any of its products unless it disclosed that the Hi-C advertising had been questioned by the Commission

Geospatial relationships of air pollution and acute asthma events across the Detroit–Windsor international border: Study design and preliminary results

The Geospatial Determinants of Health Outcomes Consortium (GeoDHOC) study investigated ambient air quality across the international border between Detroit, Michigan, USA and Windsor, Ontario, Canada and its association with acute asthma events in 5- to 89-year-old residents of these cities. NO2, SO2, and volatile organic compounds (VOCs) were measured at 100 sites, and particulate matter (PM) and polycyclic aromatic hydrocarbons (PAHs) at 50 sites during two 2-week sampling periods in 2008 and 2009. Acute asthma event rates across neighborhoods in each city were calculated using emergency room visits and hospitalizations and standardized to the overall age and gender distribution of the population in the two cities combined. Results demonstrate that intra-urban air quality variations are related to adverse respiratory events in both cities. Annual 2008 asthma rates exhibited statistically significant positive correlations with total VOCs and total benzene, toluene, ethylbenzene and xylene (BTEX) at 5-digit zip code scale spatial resolution in Detroit. In Windsor, NO2, VOCs, and PM10 concentrations correlated positively with 2008 asthma rates at a similar 3-digit postal forward sortation area scale. The study is limited by its coarse temporal resolution (comparing relatively short term air quality measurements to annual asthma health data) and interpretation of findings is complicated by contrasts in population demographics and health-care delivery systems in Detroit and Windsor

Warm Dust and Spatially Variable PAH Emission in the Dwarf Starburst Galaxy NGC 1705

We present Spitzer observations of the dwarf starburst galaxy NGC 1705 obtained as part of SINGS. The galaxy morphology is very different shortward and longward of ~5 microns: short-wavelength imaging shows an underlying red stellar population, with the central super star cluster (SSC) dominating the luminosity; longer-wavelength data reveals warm dust emission arising from two off-nuclear regions offset by ~250 pc from the SSC. These regions show little extinction at optical wavelengths. The galaxy has a relatively low global dust mass (~2E5 solar masses, implying a global dust-to-gas mass ratio ~2--4 times lower than the Milky Way average). The off-nuclear dust emission appears to be powered by photons from the same stellar population responsible for the excitation of the observed H Alpha emission; these photons are unassociated with the SSC (though a contribution from embedded sources to the IR luminosity of the off-nuclear regions cannot be ruled out). Low-resolution IRS spectroscopy shows moderate-strength PAH emission in the 11.3 micron band in the eastern peak; no PAH emission is detected in the SSC or the western dust emission complex. There is significant diffuse 8 micron emission after scaling and subtracting shorter wavelength data; the spatially variable PAH emission strengths revealed by the IRS data suggest caution in the interpretation of diffuse 8 micron emission as arising from PAH carriers alone. The metallicity of NGC 1705 falls at the transition level of 35% solar found by Engelbracht and collaborators; the fact that a system at this metallicity shows spatially variable PAH emission demonstrates the complexity of interpreting diffuse 8 micron emission. A radio continuum non-detection, NGC 1705 deviates significantly from the canonical far-IR vs. radio correlation. (Abridged)Comment: ApJ, in press; please retrieve full-resolution version from http://www.astro.wesleyan.edu/~cannon/pubs.htm

Evaluating Depressive Symptoms in Schizophrenia: A Psychometric Comparison of the Calgary Depression Scale for Schizophrenia and the Hamilton Depression Rating Scale

Background: The aim of this study was to compare two measures of depression in patients with schizophrenia and schizophrenia spectrum disorder, including patients with delusional and schizoaffective disorder, to conclude implications for their application. Sampling and Methods: A total of 278 patients were assessed using the Calgary Depression Scale for Schizophrenia (CDSS) and the Hamilton Depression Rating Scale (HAMD-17). The Positive and Negative Syndrome Scale (PANSS) was also applied. At admission and discharge, a principal component analysis was performed with each depression scale. The two depression rating scales were furthermore compared using correlation and regression analyses. Results: Three factors were revealed for the CDSS and HAMD-17 factor component analysis. A very similar item loading was found for the CDSS at admission and discharge, whereas results of the loadings of the HAMD-17 items were less stable. The first two factors of the CDSS revealed correlations with positive, negative and general psychopathology. In contrast, multiple significant correlations were found for the HAMD-17 factors and the PANSS sub-scores. Multiple regression analyses demonstrated that the HAMD-17 accounted more for the positive and negative symptom domains than the CDSS. Conclusions:The present results suggest that compared to the HAMD-17, the CDSS is a more specific instrument to measure depressive symptoms in schizophrenia and schizophrenia spectrum disorder, especially in acutely ill patients. Copyright (c) 2012 S. Karger AG, Base

Two novel missense mutations in the myelin protein zero gene causes Charcot-Marie-Tooth type 2 and Déjérine-Sottas syndrome

<p>Abstract</p> <p>Background</p> <p>The Charcot-Marie-Tooth (CMT) phenotype caused by mutation in the <it>myelin protein zero (MPZ) </it>gene varies considerably, from early onset and severe forms to late onset and milder forms. The mechanism is not well understood. The myelin protein zero (P₀) mediates adhesion in the spiral wraps of the Schwann cell's myelin sheath. The crystalline structure of the extracellular domain of the myelin protein zero (P₀ex) is known, while the transmembrane and intracellular structure is unknown.</p> <p>Findings</p> <p>One novel missense mutation caused a milder late onset CMT type 2, while the second missense mutation caused a severe early onset phenotype compatible with Déjérine-Sottas syndrome.</p> <p>Conclusions</p> <p>The phenotypic variation caused by different missense mutations in the <it>MPZ </it>gene is likely caused by different conformational changes of the MPZ protein which affects the functional tetramers. Severe changes of the MPZ protein cause dysfunctional tetramers and predominantly uncompacted myelin, i.e. the severe phenotypes congenital hypomyelinating neuropathy and Déjérine-Sottas syndrome, while milder changes cause the phenotypes CMT type 1 and 2.</p

The Behavior of the Aromatic Features in M101 HII Regions: Evidence for Dust Processing

The aromatic features in M101 were studied spectroscopically and photometrically using observations from all three instruments on the Spitzer Space Telescope. The global SED of M101 shows strong aromatic feature (commonly called PAH feature) emission. The spatially resolved spectral and photometric measurements of the aromatic feature emission show strong variations with significantly weaker emission at larger radii. We compare these variations with changes in the ionization index (as measured by [NeIII]/[NeII] and [SIV/SIII], which we probe over the ranges 0.03-20 and 0.044-15 respectively) and metallicity (expressed as log(O/H)+12, which ranges from 8.1 to 8.8). Over these ranges, the spectroscopic equivalent widths of the aromatic features from 7 HII regions and the nucleus were found to correlate better with ionization index than with metallicity. This implies that the weakening of the aromatic emission in massive star forming regions is due primarily to processing of the dust grains in these environments, not to differences in how they form (although formation could still be important on a secondary basis). The behavior of the correlation between the aromatic feature equivalent widths and ionization index can be described as a constant equivalent width until a threshold in ionization index is reached ([NeIII]/[NeII] ~ 1), above which the equivalent widths decrease with a power law dependence. This behavior for M101 HII regions is also seen for the sample of starburst galaxies presented in the companion study of Engelbracht et al. (2008) which expands the range of [NeIII]/[NeII] ratios to 0.03-25 and log(O/H)+12 values to 7.1-8.8. The form of the correlation explains seemingly contradictory results present in the literature. [abridged]Comment: 20 pages, 18 figures, ApJ, in press, (version with full resolution figures at http://dirty.as.arizona.edu/~kgordon/papers/PS_files/m101_aromatics.pdf

Ultra-Strong Machine Learning: comprehensibility of programs learned with ILP

During the 1980s Michie defined Machine Learning in terms of two orthogonal axes of performance: predictive accuracy and comprehensibility of generated hypotheses. Since predictive accuracy was readily measurable and comprehensibility not so, later definitions in the 1990s, such as Mitchell’s, tended to use a one-dimensional approach to Machine Learning based solely on predictive accuracy, ultimately favouring statistical over symbolic Machine Learning approaches. In this paper we provide a definition of comprehensibility of hypotheses which can be estimated using human participant trials. We present two sets of experiments testing human comprehensibility of logic programs. In the first experiment we test human comprehensibility with and without predicate invention. Results indicate comprehensibility is affected not only by the complexity of the presented program but also by the existence of anonymous predicate symbols. In the second experiment we directly test whether any state-of-the-art ILP systems are ultra-strong learners in Michie’s sense, and select the Metagol system for use in humans trials. Results show participants were not able to learn the relational concept on their own from a set of examples but they were able to apply the relational definition provided by the ILP system correctly. This implies the existence of a class of relational concepts which are hard to acquire for humans, though easy to understand given an abstract explanation. We believe improved understanding of this class could have potential relevance to contexts involving human learning, teaching and verbal interaction