247 research outputs found

    Susceptibility characterization of beam pipe radiated noise for the PXD detector in Belle II experiment

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    The new Pixel Vertex Detector (PXD) used in the upgrade of the high energy physics experiment Belle II is based on the DEPFET technology. Since the PXD is 2 mm far from the beam pipe, the effects of radiated interferences may be taken into account. Though the EM wave associated to the beam is very well confined (skin depth), the beam pipe is grounded to the accelerator and it may have noise currents on its external face due to pumps, auxiliary electronics, power converters, etc. which may produce radiated noise (H field). This analysis is part of the EMC approach that covers the analysis of the emissions and immunity characteristics, as well as the coupling phenomena and grounding issues to define the susceptibility levels required to ensure the successful integration of the detector and, specifically, to achieve the designed performance of the front-end electronics

    Spontaneous Formation and Rearrangement of Artificial Lipid Nanotube Networks as a Bottom-Up Model for Endoplasmic Reticulum

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    We present a convenient method to form a bottom-up structural organelle model for the endoplasmic reticulum (ER). The model consists of highly dense lipidic nanotubes that are, in terms of morphology and dynamics, reminiscent of ER. The networks are derived from phospholipid double bilayer membrane patches adhering to a transparent Al2O3 substrate. The adhesion is mediated by Ca2+ in the ambient buffer. Subsequent depletion of Ca2+ by means of BAPTA/EDTA causes retraction of the membrane, resulting in spontaneous lipid nanotube network formation. The method only comprises phospholipids and microfabricated surfaces for simple formation of an ER model and does not require the addition of proteins or chemical energy (e.g., GTP or ATP). In contrast to the 3D morphology of the cellular endoplasmic reticulum, the model is two-dimensional (albeit the nanotube dimensions, geometry, structure, and dynamics are maintained). This unique in vitro ER model consists of only a few components, is easy to construct, and can be observed under a light microscope. The resulting structure can be further decorated for additional functionality, such as the addition of ER-associated proteins or particles to study transport phenomena among the tubes. The artificial networks described here are suitable structural models for the cellular ER, whose unique characteristic morphology has been shown to be related to its biological function, whereas details regarding formation of the tubular domain and rearrangements within are still not completely understood. We note that this method uses Al2O3 thin-film-coated microscopy coverslips, which are commercially available but require special orders. Therefore, it is advisable to have access to a microfabrication facility for preparation

    THE MUST MODEL EVALUATION EXERCISE: STATISTICAL ANALYSIS OF MODELLING RESULTS

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    The first validation exercise of the COST action 732 lead to a substantial number of simulation results for comparison with the MUST wind tunnel experiments. Validation metrics for selected simulation results of the flow field and the concentrations are presented and compared to the state of the art. In addition mean metrics and corresponding scatter limits are computed from the individual results

    THE MUST MODEL EVALUATION EXERCISE: PATTERNS IN MODEL PERFORMANCE

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    As part of the COST 732 action more than a dozen different research groups have modelled the MUST experiment, as simulated in a wind tunnel. The model evaluation guidance developed within COST 732 recommends \u27exploratory data analysis\u27 as one of the elements in model validation. Experience has shown that such exploratory analysis is crucial to reveal shortcomings of models that might otherwise pass unnoticed. Conditions are best for detecting common patterns and anomalies if you have a situation where several models are put into a common framework – like the case at hand. The available material provides a unique opportunity to identify and explore patterns within model performance

    Simulating the performance of the Southern Wide-view Gamma-ray Observatory

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    The Southern Wide-view Gamma-ray Observatory (SWGO) will be a next-generation gamma-ray observatory using a large array of particle detectors at a high elevation site in South America. This project is currently in a three years R&D phase in which the design will be optimised for cost and performance. Therefore it is crucial to efficiently evaluate the impact of different design options on the scientific objectives of the observatory. In this contribution, we will introduce the strategy and the simulation framework in which this evaluation takes place

    The Southern Wide-field Gamma-ray Observatory reach for Primordial Black Hole evaporation

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    The Southern Wide-field Gamma-ray Observatory (SWGO) is a proposed ground-based gamma-ray detector that will be located in the Southern Hemisphere and is currently in its design phase. In this contribution, we will outline the prospects for Galactic science with this Observatory. Particular focus will be given to the detectability of extended sources, such as gamma-ray halos around pulsars; optimisation of the angular resolution to mitigate source confusion between known TeV sources; and studies of the energy resolution and sensitivity required to study the spectral features of PeVatrons at the highest energies. Such a facility will ideally complement contemporaneous observatories in studies of high energy astrophysical processes in our Galaxy

    Galactic Science with the Southern Wide-field Gamma-ray Observatory

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    The Southern Wide-field Gamma-ray Observatory (SWGO) is a proposed ground-based gamma-ray detector that will be located in the Southern Hemisphere and is currently in its design phase. In this contribution, we will outline the prospects for Galactic science with this Observatory. Particular focus will be given to the detectability of extended sources, such as gamma-ray halos around pulsars; optimisation of the angular resolution to mitigate source confusion between known TeV sources; and studies of the energy resolution and sensitivity required to study the spectral features of PeVatrons at the highest energies. Such a facility will ideally complement contemporaneous observatories in studies of high energy astrophysical processes in our Galaxy
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