A phylogeny of members of the family Taeniidae based on the mitochondrial cox1 and nad1 gene data

nad1 gene dat

Radio Bursts Associated with Flare and Ejecta in the 13 July 2004 Event

We investigate coronal transients associated with a GOES M6.7 class flare and a coronal mass ejection (CME) on 13 July 2004. During the rising phase of the flare, a filament eruption, loop expansion, a Moreton wave, and an ejecta were observed. An EIT wave was detected later on. The main features in the radio dynamic spectrum were a frequency-drifting continuum and two type II bursts. Our analysis shows that if the first type II burst was formed in the low corona, the burst heights and speed are close to the projected distances and speed of the Moreton wave (a chromospheric shock wave signature). The frequency-drifting radio continuum, starting above 1 GHz, was formed almost two minutes prior to any shock features becoming visible, and a fast-expanding piston (visible as the continuum) could have launched another shock wave. A possible scenario is that a flare blast overtook the earlier transient, and ignited the first type II burst. The second type II burst may have been formed by the same shock, but only if the shock was propagating at a constant speed. This interpretation also requires that the shock-producing regions were located at different parts of the propagating structure, or that the shock was passing through regions with highly different atmospheric densities. This complex event, with a multitude of radio features and transients at other wavelengths, presents evidence for both blast-wave-related and CME-related radio emissions.Comment: 14 pages, 6 figures; Solar Physics Topical Issue, in pres

Planet Hunters IX. KIC 8462852 - Where\u27s the flux?

Over the duration of the Kepler mission, KIC 8462852 was observed to undergo irregularly shaped, aperiodic dips in flux of up to ~20 per cent. The dipping activity can last for between 5 and 80 d.We characterize the object with high-resolution spectroscopy, spectral energy distribution fitting, radial velocity measurements, high-resolution imaging, and Fourier analyses of the Kepler light curve. We determine that KIC 8462852 is a typical main-sequence F3 V star that exhibits no significant IR excess, and has no very close interacting companions. In this paper, we describe various scenarios to explain the dipping events observed in the Kepler light curve.We confirm that the dipping signals in the data are not caused by any instrumental or data processing artefact, and thus are astrophysical in origin. We construct scenario-independent constraints on the size and location of a body in the system that are needed to reproduce the observations. We deliberate over several assorted stellar and circumstellar astrophysical scenarios, most of which have problems explaining the data in hand. By considering the observational constraints on dust clumps in orbit around a normal main-sequence star, we conclude that the scenario most consistent with the data in hand is the passage of a family of exocomet or planetesimal fragments, all of which are associated with a single previous break-up event, possibly caused by tidal disruption or thermal processing. The minimum total mass associated with these fragments likely exceeds 10-6 M⊕, corresponding to an original rocky body of \u3e100 km in diameter. We discuss the necessity of future observations to help interpret the system

Binding of the long pentraxin PTX3 to factor H: interacting domains and function in the regulation of complement activation

The long pentraxin PTX3 is a multifunctional soluble molecule involved in inflammation and innate immunity. As an acute phase protein, PTX3 binds to the classical pathway complement protein C1q, limits tissue damage in inflammatory conditions by regulating apoptotic cell clearance, and plays a role in the phagocytosis of selected pathogens. This study was designed to investigate the interaction of PTX3 with factor H (FH), the main soluble alternative pathway regulatory protein. We report that PTX3 binds FH with an apparent Kd of 1.1 7 10-7 M, and define two binding sites for PTX3 on FH. The primary binding site is located on FH domains 19-20, which interact with the N-terminal domain of PTX3, while a secondary binding site on domain 7 binds the glycosylated PTX3 pentraxin domain. The FH Y402H polymorphism, which affects binding to the short pentraxin CRP, did not affect binding to PTX3. Surface-bound PTX3 enhances FH recruitment and iC3b deposition and PTX3-bound FH retains its activity as a cofactor for factor I-mediated C3b cleavage. Thus, our findings identify PTX3 as a unique FH ligand in that it can bind both of the two hot-spots of FH, namely SCR7 and SCR19-20 and indicate that PTX3 participates in the localization of functionally active FH. Copyrigh

Characterization of the glomerular endothelial binding sites for full-length complement factor H (FH) and for FH19-20 and FH5-7 domains

Nephrolog

Mutations in Complement Factor H Impair Alternative Pathway Regulation on Mouse Glomerular Endothelial Cells in Vitro

NephrologyVascular nephrolog