20 research outputs found
Large Scale In Silico Screening on Grid Infrastructures
Large-scale grid infrastructures for in silico drug discovery open
opportunities of particular interest to neglected and emerging diseases. In
2005 and 2006, we have been able to deploy large scale in silico docking within
the framework of the WISDOM initiative against Malaria and Avian Flu requiring
about 105 years of CPU on the EGEE, Auvergrid and TWGrid infrastructures. These
achievements demonstrated the relevance of large-scale grid infrastructures for
the virtual screening by molecular docking. This also allowed evaluating the
performances of the grid infrastructures and to identify specific issues raised
by large-scale deployment.Comment: 14 pages, 2 figures, 2 tables, The Third International Life Science
Grid Workshop, LSGrid 2006, Yokohama, Japan, 13-14 october 2006, to appear in
the proceeding
A balanced homodyne detector for high-rate Gaussian-modulated coherent-state quantum key distribution
We discuss excess noise contributions of a practical balanced homodyne
detector in Gaussian-modulated coherent-state (GMCS) quantum key distribution
(QKD). We point out the key generated from the original realistic model of GMCS
QKD may not be secure. In our refined realistic model, we take into account
excess noise due to the finite bandwidth of the homodyne detector and the
fluctuation of the local oscillator. A high speed balanced homodyne detector
suitable for GMCS QKD in the telecommunication wavelength region is built and
experimentally tested. The 3dB bandwidth of the balanced homodyne detector is
found to be 104MHz and its electronic noise level is 13dB below the shot noise
at a local oscillator level of 8.5*10^8 photon per pulse. The secure key rate
of a GMCS QKD experiment with this homodyne detector is expected to reach
Mbits/s over a few kilometers.Comment: 22 pages, 11 figure
Virtual Screening on Large Scale Grids
PCSV, article in press in Parallel ComputingLarge scale grids for in silico drug discovery open opportunities of particular interest to neglected and emerging diseases. In 2005 and 2006, we have been able to deploy large scale virtual docking within the framework of the WISDOM initiative against malaria and avian influenza requiring about 100 years of CPU on the EGEE, Auvergrid and TWGrid infrastructures. These achievements demonstrated the relevance of large scale grids for the virtual screening by molecular docking. This also allowed evaluating the performances of the grid infrastructures and to identify specific issues raised by large scale deployment
Field test of quantum key distribution in the Tokyo QKD Network
A novel secure communication network with quantum key distribution in a
metropolitan area is reported. Different QKD schemes are integrated to
demonstrate secure TV conferencing over a distance of 45km, stable long-term
operation, and application to secure mobile phones.Comment: 21 pages, 19 figure
The SHARE Road Map: Healthgrids for Biomedical Research and Healthcare.
The HealthGrid White Paper was published at the third annual conference in Oxford in 2005. Starting from the conclusions of the White Paper, the EU funded SHARE project (http://www.eu-share.org) has aimed at identifying the most important steps and significant milestones towards wide deployment and adoption of healthgrids in Europe. The project has defined a strategy to address the issues identified in the action plan for European e-Health (COM(2004).356) and has devised a roadmap for the major technological and ethical and legal developments and social and economic investments needed for successful take up of healthgrids in the next 10 years. A "beta" version of the road map underwent full review by a panel of 25 prominent European experts at a workshop in December 2007. The present document is an executive policy summary of the final draft road map. It has sought to reconcile likely conflicts between technological developments and regulatory frameworks by bringing together the project's technical road map and conceptual map of ethical and legal issues and socio-economic prospects. A key tool in this process was a collection of case studies of healthgrid applications