620 research outputs found
Do Security-differentiated Water Rights Improve Efficiency?
Most existing water markets combine water rights trading and water allocation trading. Offering different levels of security for rights can make the market more sophisticated and allow water users to manage the risks of supply uncertainty better. We compare results from a laboratory experiment with two water right designs, one with a unique security level and another with two security levels. We find that a two security levels system improves both allocative eciency and risk management, but only when transactions costs are higher in the market for water allocation than in the market for water rights.Crude Oil Pricing, Currency Basket, OPEC, Exchange Rate of Dollar, Euros, Yen.
Reporting methodological search filter performance comparisons : a literature review
© 2014 The authors. Health Information and Libraries Journal © 2014 Health Libraries Journal.Peer reviewedPostprin
Choosing and using methodological search filters : searchers' views
© 2014 The authors. Health Information and Libraries Journal © 2014 Health Libraries Group.Peer reviewedPostprin
Influence of water on the circulation of the West Nile Virus in horses in Southern France
International audienc
Assessment of Solute Transfer Between Static and Dynamic Water During Percolation Through a Solid Leach Bed in Dry Batch Anaerobic Digestion Processes
The aim of this work was to characterize solute transfer between static and dynamic water during percolation through a solid leach bed reactor. A new experimental procedure was set up to measure the solute exchange rate between macro-and micro-porosity. Tracer tests were performed in closed-circuit recirculation experiments. The water behavior was modeled by a multiphase flow model in a double porosity medium using a previously published methodology. The solute exchange rate between static and dynamic water was described by first-order kinetics. The methodology was applied to wheat straw and solid cow manure beds. The solute exchange rate (hs was 0.054 and 0.324 hâ1) for wheat straw and solid cow manure, respectively. The measured data was used to improve the prediction capacity of a CFD tool. The results of this work could be used to develop appropriate leachate recirculation strategies to optimize full-scale dry batch anaerobic digestion processes
O-GlcNAc transferase associates with the MCM2-7 complex and its silencing destabilizes MCM-MCM interactions
International audienceO-GlcNAcylation of proteins is governed by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). The homeostasis of O-GlcNAc cycling is regulated during cell cycle progression and is essential for proper cellular division. We previously reported the O-GlcNAcylation of the Mini-Chromosome Maintenance proteins MCM2, MCM3, MCM6 and MCM7. These proteins belong to the MCM2-7 complex which is crucial for the initiation of DNA replication through its DNA helicase activity. Here we show that the six subunits of MCM2-7 are O-GlcNAcylated and that O-GlcNAcylation of MCM proteins mainly occurs in the chromatin-bound fraction of synchronized human cells. Moreover, we identify stable interaction between OGT and several MCM subunits. We also show that down-regulation of OGT decreases the chromatin binding of MCM2, MCM6 and MCM7 without affecting their steady-state level. Finally, OGT silencing or OGA inhibition destabilize MCM2/6 and MCM4/7 interactions in the chromatin-enriched fraction. In conclusion, OGT is a new partner of the MCM2-7 complex and O-GlcNAcylation homeostasis might regulate MCM2-7 complex by regulating the chromatin loading of MCM6 and MCM7 and stabilizing MCM/MCM interactions
Why us? Perceived injustice is associated with more sexual and psychological distress in couples coping with genito-pelvic pain
Introduction
Provoked vestibulodynia (PVD) is the most frequent cause of genito-pelvic pain/penetration disorder (GPPPD) and is associated with negative psychological and sexual consequences for affected women and their partners. PVD is often misdiagnosed or ignored and many couples may experience a sense of injustice, due to the loss of their ability to have a normal sexual life. Perceiving injustice has been documented to have important consequences in individuals with chronic pain. However, no quantitative research has investigated the experience of injustice in this population.
Aim
The aim of this study was to investigate the associations between perceived injustice and pain, sexual satisfaction, sexual distress, and depression among women with PVD and their partners.
Methods
Women diagnosed with PVD (N = 50) and their partners completed questionnaires of perceived injustice, pain, sexual satisfaction, sexual distress, and depression.
Main Outcome Measures
(1) Global Measure of Sexual Satisfaction Scale; (2) Female Sexual Distress Scale; (3) Beck Depression Inventory-II; and (4) McGill-Melzack Pain Questionnaire.
Results
After controlling for partners' age, women's higher level of perceived injustice was associated with their own greater sexual distress, and the same pattern was found for partners. Women's higher level of perceived injustice was associated with their own greater depression, and the same pattern was found for partners. Women's higher perceived injustice was not associated with their own lower sexual satisfaction but partners' higher perceived injustice was associated with their own lower sexual satisfaction. Perceived injustice was not associated with women's pain intensity.
Conclusion
Results suggest that perceiving injustice may have negative consequences for the couple's sexual and psychological outcomes. However, the effects of perceived injustice appear to be intra-individual. Targeting perceived injustice could enhance the efficacy of psychological interventions for women with PVD and their partners
(How) can economic experiments inform EU agricultural policy?
This report provides an overview of the potential contribution of economic experiments to the Common Agricultural Policy evaluation toolbox. The methodology of economic experiments is briefly described in chapter 2. Chapter 3 presents examples of experimental studies relevant for the analysis of the Common Agricultural Policy. Chapter 4 discusses whether there is room for economic experiments in the EU evaluation toolbox. Chapter 5 identifies the main challenges when implementing economic experiments. Chapter 6 provides a set of recommendations, arising from the discussions between the authors of this report and policy officers from DG AGRI, relative to the introduction of economic experiments in the CAP evaluation toolbox.JRC.J.4-Agriculture and Life Sciences in the Econom
Problemes d'ordonnancement d'une superposition de flux periodiques sous contrainte temps-reel
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Les documents scientifiques informels: un patrimoine peu exploré, témoin de la construction des savoirs
L'objectif du projet ECRITO Ă©tait de contribuer Ă prĂ©server et Ă valoriser les documents scientifiques produits quotidiennement par les chercheurs de Midi-PyrĂ©nĂ©es, en amont des publications formelles : non seulement les articles, communications ou monographies, qui constituent la partie visible de la recherche, mais aussi tous les matĂ©riaux et informations accumulĂ©s par les chercheurs, et sur la base desquels se construit leur travail. Ces matĂ©riaux sont de types trĂšs divers : littĂ©rature " grise " (rapports, mĂ©moires, documentation techniques...), documents textuels " informels " (carnets, notes, brouillons, correspondances, cahiers de laboratoires), corpus visuels, sonores ou multimĂ©dia (campagnes photographiques, campagnes d'enquĂȘtes, enregistrements audio ou vidĂ©o), donnĂ©es Ă©lectroniques (bases de donnĂ©es, fichiers informatiques), etc. Le projet visait Ă©galement Ă prolonger, de maniĂšre exploratoire, le questionnement sur le patrimoine scientifique Ă partir des traces matĂ©rielles produites quotidiennement par les chercheurs dans leurs activitĂ©s de recherche. Ces traces reprĂ©sentent en effet une fenĂȘtre irremplaçable sur la science en train de se construire : elles permettent de rendre visible et comprĂ©hensible le processus habituellement dissimulĂ© de production de la science, ce qui constitue un enjeu scientifique et pĂ©dagogique fondamental
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