2,451 research outputs found
B-L-violating Masses in Softly Broken Supersymmetry
We prove a general low-energy theorem establishing a generic relation between
the neutrino Majorana mass and the superpartner sneutrino B-L-violating
"Majorana"-like mass term. The theorem states that, if one of these two
quantities is non-zero the other one is also non-zero and, vice versa, if one
of them vanishes the other vanishes, too. The theorem is a consequence of the
underlying supersymmetry (SUSY) and valid for any realistic gauge model with
weak scale softly broken SUSY.Comment: 7 pages, Latex, 1 Postscript figur
An evaluation of combined geophysical and geotechnical methods to characterize beach thickness
Beaches provide sediment stores and have an important role in the development of the coastline in response to climate change. Quantification of beach thickness and volume is required to assess coastal sediment transport budgets. Therefore, portable, rapid, non-invasive techniques are required to evaluate thickness where environmental sensitivities exclude invasive methods. Site methods and data are described for a toolbox of electrical, electromagnetic, seismic and mechanical based techniques that were evaluated at a coastal site at Easington, Yorkshire. Geophysical and geotechnical properties are shown to be dependent upon moisture content, porosity and lithology of the beach and the morphology of the beach–platform interface. Thickness interpretation, using an inexpensive geographic information system to integrate data, allowed these controls and relationships to be understood. Guidelines for efficient site practices, based upon this case history including procedures and techniques, are presented using a systematic approach. Field results indicated that a mixed sand and gravel beach is highly variable and cannot be represented in models as a homogeneous layer of variable thickness overlying a bedrock half-space
A new route to the Mott-Hubbard metal-insulator transition: Strong correlations effects in Pr0.7 Ca0.3 MnO3
Resistive random access memory based on the resistive switching phenomenon is emerging as a strong candidate for next generation non-volatile memory. So far, the resistive switching effect has been observed in many transition metal oxides, including strongly correlated ones, such as, cuprate superconductors, colossal magnetoresistant manganites and Mott insulators. However, up to now, no clear evidence of the possible relevance of strong correlation effects in the mechanism of resistive switching has been reported. Here, we study Pr 0.7 Ca0.3 MnO3, which shows bipolar resistive switching. Performing micro-spectroscopic studies on its bare surface we are able to track the systematic electronic structure changes in both, the low and high resistance state. We find that a large change in the electronic conductance is due to field-induced oxygen vacancies, which drives a Mott metal-insulator transition at the surface. Our study demonstrates that strong correlation effects may be incorporated to the realm of the emerging oxide electronics.Fil:Rozenberg, M.J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina
Physical Origin, Evolution and Observational Signature of Diffused Antiworld
The existence of macroscopic regions with antibaryon excess in the baryon
asymmetric Universe with general baryon excess is the possible consequence of
practically all models of baryosynthesis. Diffusion of matter and antimatter to
the border of antimatter domains defines the minimal scale of the antimatter
domains surviving to the present time. A model of diffused antiworld is
considered, in which the density within the surviving antimatter domains is too
low to form gravitationally bound objects. The possibility to test this model
by measurements of cosmic gamma ray fluxes is discussed. The expected gamma ray
flux is found to be acceptable for modern cosmic gamma ray detectors and for
those planned for the near future.Comment: 9 page
Nonconcentration of energy for a semilinear Skyrme model
We continue our investigation of a model introduced by Adkins and Nappi, in
which omega mesons stabilize chiral solitons. The aim of this article is to
show that the energy associated to equivariant solutions does not concentrate.Comment: 12 pages, 2 figure
Owl and Lizard: Patterns of Head Pose and Eye Pose in Driver Gaze Classification
Accurate, robust, inexpensive gaze tracking in the car can help keep a driver
safe by facilitating the more effective study of how to improve (1) vehicle
interfaces and (2) the design of future Advanced Driver Assistance Systems. In
this paper, we estimate head pose and eye pose from monocular video using
methods developed extensively in prior work and ask two new interesting
questions. First, how much better can we classify driver gaze using head and
eye pose versus just using head pose? Second, are there individual-specific
gaze strategies that strongly correlate with how much gaze classification
improves with the addition of eye pose information? We answer these questions
by evaluating data drawn from an on-road study of 40 drivers. The main insight
of the paper is conveyed through the analogy of an "owl" and "lizard" which
describes the degree to which the eyes and the head move when shifting gaze.
When the head moves a lot ("owl"), not much classification improvement is
attained by estimating eye pose on top of head pose. On the other hand, when
the head stays still and only the eyes move ("lizard"), classification accuracy
increases significantly from adding in eye pose. We characterize how that
accuracy varies between people, gaze strategies, and gaze regions.Comment: Accepted for Publication in IET Computer Vision. arXiv admin note:
text overlap with arXiv:1507.0476
Quantum Monte Carlo treatment of elastic exciton-exciton scattering
We calculate cross sections for low energy elastic exciton-exciton scattering
within the effective mass approximation. Unlike previous theoretical
approaches, we give a complete, non-perturbative treatment of the four-particle
scattering problem. Diffusion Monte Carlo is used to calculate the essentially
exact energies of scattering states, from which phase shifts are determined.
For the case of equal-mass electrons and holes, which is equivalent to
positronium-positronium scattering, we find a_s = 2.1 a_x for scattering of
singlet-excitons and a_s= 1.5 a_x for triplet-excitons, where a_x is the
excitonic radius. The spin dependence of the cross sections arises from the
spatial exchange symmetry of the scattering wavefunctions. A significant
triplet-triplet to singlet-singlet scattering process is found, which is
similar to reported effects in recent experiments and theory for excitons in
quantum wells. We also show that the scattering length can change sign and
diverge for some values of the mass ratio m_h/m_e, an effect not seen in
previous perturbative treatments.Comment: 6 pages, 6 figures. Revision has updated figures, improved paper
structure, some minor correction
Differential attainment at MRCS according to gender, ethnicity, age and socioeconomic factors : A retrospective cohort study
Open access via Sage agreement Acknowledgements The authors would like to acknowledge Iain Targett at the Royal College of Surgeons of England, for his help with data collection and John Hines and Gregory Ayre from the Intercollegiate Committee for Basic Surgical Examinations for their support during this project. Our thanks to members of the UKMED Research Group who provided useful feedback on an earlier version of this manuscript, and whose comments helped refine the paper. The authors would also like to acknowledge Daniel Smith for his help with the UKMED database. Data Source: UK Medical Education Database (“UKMED”). UKMEDP043 extract generated on 25 July 2018. We are grateful to UKMED for the use of these data. However, UKMED bears no responsibility for their analysis or interpretation. The data include information derived from that collected by the Higher Education Statistics Agency (“HESA”) Limited and provided to the GMC (“HESA Data”). Source: HESA Student Records 2007/2008 to 2015/2016. Copyright Higher Education Statistics Agency Limited. The Higher Education Statistics Agency Limited makes no warranty as to the accuracy of the HESA Data, cannot accept responsibility for any inferences or conclusions derived by third parties from data or other Information supplied by it. The dataset used in this study was acquired from the UK Medical Education Database and is held in Safe Haven. All counts have been rounded to the nearest 5 according to HESA data standards to ensure person-level anonymity, as per UKMED policy. Data access requests must be made to UKMED. Full information for applications can be found at https://www.ukmed.ac.uk.Peer reviewedPublisher PD
The small fiber neuropathy NaV1.7 I228M mutation: impaired neurite integrity via bioenergetic and mitotoxic mechanisms, and protection by dexpramipexole
Gain-of-function variants in voltage-gated sodium channel NaV1.7 that increase firing frequency and spontaneous firing of dorsal root ganglion (DRG) neurons have recently been identified in 5-10% of patients with idiopathic small fiber neuropathy (I-SFN). Our previous in vitro observations suggest that enhanced sodium channel activity can contribute to a decrease in length of peripheral sensory axons. We have hypothesized that sustained sodium influx due to the expression of SFN-associated sodium channel variants may trigger an energetic deficit in neurons that contributes to degeneration and loss of nerve fibers in SFN. Using an ATP FRET biosensor, we now demonstrate reduced steady-state levels of ATP and markedly faster ATP decay in response to membrane depolarization in cultured DRG neurons expressing an SFN-associated variant NaV1.7, I228M, compared with wild-type neurons. We also observed that I228M neurons show a significant reduction in mitochondrial density and size, indicating dysfunctional mitochondria and a reduced bioenergetic capacity. Finally, we report that exposure to dexpramipexole, a drug that improves mitochondrial energy metabolism, increases the neurite length of I228M-expressing neurons. Our data suggest that expression of gain-of-function variants of NaV1.7 can damage mitochondria and compromise cellular capacity for ATP production. The resulting bioenergetic crisis can consequently contribute to loss of axons in SFN. We suggest that, in addition to interventions that reduce ionic disturbance caused by mutant NaV1.7 channels, an alternative therapeutic strategy might target the bioenergetic burden and mitochondrial damage that occur in SFN associated with NaV1.7 gain-of-function mutations.NEW & NOTEWORTHY Sodium channel NaV1.7 mutations that increase dorsal root ganglion (DRG) neuron excitability have been identified in small fiber neuropathy (SFN). We demonstrate reduced steady-state ATP levels, faster depolarization-evoked ATP decay, and reduced mitochondrial density and size in cultured DRG neurons expressing SFN-associated variant NaV1.7 I228M. Dexpramipexole, which improves mitochondrial energy metabolism, has a protective effect. Because gain-of-function NaV1.7 variants can compromise bioenergetics, therapeutic strategies that target bioenergetic burden and mitochondrial damage merit study in SFN
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