Kinetics of binding and geometry of cells on molecular biochips

We examine how the shape of cells and the geometry of experiment affect the reaction-diffusion kinetics at the binding between target and probe molecules on molecular biochips. In particular, we compare the binding kinetics for the probes immobilized on surface of the semispherical and flat circular cells, the limit of thin slab of analyte solution over probe cell as well as hemispherical gel pads and cells printed in gel slab over a substrate. It is shown that hemispherical geometry provides significantly faster binding kinetics and ensures more spatially homogeneous distribution of local (from a pixel) signals over a cell in the transient regime. The advantage of using thin slabs with small volume of analyte solution may be hampered by the much longer binding kinetics needing the auxiliary mixing devices. Our analysis proves that the shape of cells and the geometry of experiment should be included to the list of essential factors at biochip designing.Comment: 10 pages, 1 figur

Antimatter Bounds by Anti-Asteroids annihilations on Planets and Sun

The existence of antimatter stars in the Galaxy as possible signature for inflationary models with non-homogeneous baryo-synthesis may leave the trace by antimatter cosmic rays as well as by their secondaries (anti-planets and anti-meteorites) diffused bodies in our galactic halo. The anti-meteorite flux may leave its explosive gamma signature by colliding on lunar soil as well as on terrestrial, jovian and solar atmospheres. However the propagation in galaxy and the consequent evaporation in galactic matter gas suppress the lightest (m < 10^(-2)g) anti-meteorites. Anisotropic annihilation of larger anti-meteorites within a narrow mass window, maybe rarely deflected, bounced by the galactic gas disk, escaping detection in our solar system. Nevertheless heaviest anti-meteorites (m > 10^(-1)g up to 10^(6)g) are unable to be deflected by the thin galactic gas surface annihilation; they might hit the Sun (or rarely Jupiter) leading to an explosive gamma event and a spectacular track with a bouncing and even a propelling annihilation on cromosphere and photosphere. Their anti-nuclei annihilation in pions and their final hard gammas showering may be observabe as a "solar flare" at a rate nearly comparable to the observed ones. From their absence we may infer bounds on antimatter-matter ratio near or below 10^(-9) limit: already recorded data in BATSE catalog might be applied.Comment: 6 pages, more accurate estimate and minor correction

Physical Origin, Evolution and Observational Signature of Diffused Antiworld

The existence of macroscopic regions with antibaryon excess in the baryon asymmetric Universe with general baryon excess is the possible consequence of practically all models of baryosynthesis. Diffusion of matter and antimatter to the border of antimatter domains defines the minimal scale of the antimatter domains surviving to the present time. A model of diffused antiworld is considered, in which the density within the surviving antimatter domains is too low to form gravitationally bound objects. The possibility to test this model by measurements of cosmic gamma ray fluxes is discussed. The expected gamma ray flux is found to be acceptable for modern cosmic gamma ray detectors and for those planned for the near future.Comment: 9 page

Spontaneous mass current and textures of p-wave superfluids of trapped Fermionic atom gases at rest and under rotation

It is found theoretically based on the Ginzburg-Landau framework that p-wave superfluids of neutral atom gases in three dimension harmonic traps exhibit spontaneous mass current at rest, whose direction depends on trap geometry. Under rotation various types of the order parameter textures are stabilized, including Mermin-Ho and Anderson-Toulouse-Chechetkin vortices. In a cigar shape trap spontaneous current flows longitudial to the rotation axis and thus perpendicular to the ordinary rotational current. These features, spontaneous mass current at rest and texture formation, can be used as diagnoses for p-wave superfluidity.Comment: 5 pages, 5 figure