Genomic, evolutionary, and expression analyses of cee, an ancient gene involved in normal growth and development

AbstractThe cee (conserved edge expressed protein) gene was recently identified in a genome-wide screen to discover genes associated with myotube formation in fast muscle of pufferfish. Comparative genomic analyses indicate that cee arose some 1.6–1.8 billion years ago and is found as a single-copy gene in most eukaryotic genomes examined. The complexity of its structure varies from an intronless gene in yeast and tunicates to nine exons and eight introns in vertebrates. cee is particularly conserved among vertebrates and is located in a syntenic region within tetrapods and between teleosts and invertebrates. Low dN/dS ratios in the cee coding region (0.02–0.09) indicate that the Cee protein is under strong purifying selection. In Atlantic salmon, cee is expressed in the superficial layers of developing organs and tissues. These data, together with functional screens in yeast and Caenorhabditis elegans, indicate that cee has a hitherto uncharacterized role in normal growth and development

Mesh update techniques for free-surface flow solvers using spectral element method

This paper presents a novel mesh-update technique for unsteady free-surface Newtonian flows using spectral element method and relying on the arbitrary Lagrangian--Eulerian kinematic description for moving the grid. Selected results showing compatibility of this mesh-update technique with spectral element method are given

Gauge hierarchy from a topological viewpoint?

In this work we explore an alternative to the central point of the Randall-Sundrum brane world scenario, namely, the particular nonfactorizable metric, in order to solve the hierarchy problem. From a topological viewpoint, we show that the exponential factor, crucial in the Randall-Sundrum model, appears in our approach, only due to the brane existence instead of a special metric background. Our results are based in a topological gravity theory via a non-standard interaction between scalar and non-abelian degrees of freedom and in calculations about localized modes of matter fields on the brane. We point out that we obtain the same results of the Randall-Sundrum model using only one 3-brane, since a specific choice of a background metric is no longer required.Comment: 10 pages, to appear in Physics Letters

Interference-induced gain in Autler-Townes doublet of a V-type atom in a cavity

We study the Autler-Townes spectrum of a V-type atom coupled to a single-mode, frequency-tunable cavity field at finite termperature, with a pre-selected polarization in the bad cavity limit, and show that, when the mean number of thermal photons $N\gg 1$ and the excited sublevel splitting is very large (the same order as the cavity linewidth), the probe gain may occur at either sideband of the doublet, depending on the cavity frequency, due to the cavity-induced interference.Comment: Minor changes are mad

Controlling laser spectra in a phaseonium photonic crystal using maser

We study the control of quantum resonances in photonic crystals with electromagnetically induced transparency driven by microwave field. In addition to the control laser, the intensity and phase of the maser can alter the transmission and reflection spectra in interesting ways, producing hyperfine resonances through the combined effects of multiple scattering in the superstructure.Comment: 7 pages, 4 figure

Thermodynamics of doubly charged CGHS model and D1-D5-KK black holes of IIB supergravity

We study the doubly charged Callan-Giddings-Harvey-Strominger (CGHS) model, which has black hole solutions that were found to be U-dual to the D1-D5-KK black holes of the IIB supergravity. We derive the action of the model via a spontaneous compactification on S^3 of the IIB supergravity on S^1*T^4 and obtain the general static solutions including black holes corresponding to certain non-asymptotically flat black holes in the IIB supergravity. Thermodynamics of them is established by computing the entropy, temperature, chemical potentials, and mass in the two-dimensional setup, and the first law of thermodynamics is explicitly verified. The entropy is in precise agreement with that of the D1-D5-KK black holes, and the mass turns out to be consistent with the infinite Lorentz boost along the M theory circle that is a part of the aforementioned U-dual chain.Comment: 21 pages, Revte

Depinning of kinks in a Josephson-junction ratchet array

We have measured the depinning of trapped kinks in a ratchet potential using a fabricated circular array of Josephson junctions. Our ratchet system consists of a parallel array of junctions with alternating cell inductances and junctions areas. We have compared this ratchet array with other circular arrays. We find experimentally and numerically that the depinning current depends on the direction of the applied current in our ratchet ring. We also find other properties of the depinning current versus applied field, such as a long period and a lack of reflection symmetry, which we can explain analytically.Comment: to be published in PR

Lyapunov Potential Description for Laser Dynamics

We describe the dynamical behavior of both class A and class B lasers in terms of a Lyapunov potential. For class A lasers we use the potential to analyze both deterministic and stochastic dynamics. In the stochastic case it is found that the phase of the electric field drifts with time in the steady state. For class B lasers, the potential obtained is valid in the absence of noise. In this case, a general expression relating the period of the relaxation oscillations to the potential is found. We have included in this expression the terms corresponding to the gain saturation and the mean value of the spontaneously emitted power, which were not considered previously. The validity of this expression is also discussed and a semi-empirical relation giving the period of the relaxation oscillations far from the stationary state is proposed and checked against numerical simulations.Comment: 13 pages (including 7 figures) LaTeX file. To appear in Phys Rev.A (June 1999

Quantum interference in the fluorescence of a molecular system

It has been observed experimentally [H.R. Xia, C.Y. Ye, and S.Y. Zhu, Phys. Rev. Lett. {\bf 77}, 1032 (1996)] that quantum interference between two molecular transitions can lead to a suppression or enhancement of spontaneous emission. This is manifested in the fluorescent intensity as a function of the detuning of the driving field from the two-photon resonance condition. Here we present a theory which explains the observed variation of the number of peaks with the mutual polarization of the molecular transition dipole moments. Using master equation techniques we calculate analytically as well as numerically the steady-state fluorescence, and find that the number of peaks depends on the excitation process. If the molecule is driven to the upper levels by a two-photon process, the fluorescent intensity consists of two peaks regardless of the mutual polarization of the transition dipole moments. If the excitation process is composed of both a two-step one-photon process and a one-step, two-photon process, then there are two peaks on transitions with parallel dipole moments and three peaks on transitions with antiparallel dipole moments. This latter case is in excellent agreement with the experiment.Comment: 11 pages, including 8 figure