2009 Influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore

10.1001/jama.2010.404JAMA - Journal of the American Medical Association303141383-139

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error.

Corneal curvature, a highly heritable trait, is a key clinical endophenotype for myopia - a major cause of visual impairment and blindness in the world. Here we present a trans-ethnic meta-analysis of corneal curvature GWAS in 44,042 individuals of Caucasian and Asian with replication in 88,218 UK Biobank data. We identified 47 loci (of which 26 are novel), with population-specific signals as well as shared signals across ethnicities. Some identified variants showed precise scaling in corneal curvature and eye elongation (i.e. axial length) to maintain eyes in emmetropia (i.e. HDAC11/FBLN2 rs2630445, RBP3 rs11204213); others exhibited association with myopia with little pleiotropic effects on eye elongation. Implicated genes are involved in extracellular matrix organization, developmental process for body and eye, connective tissue cartilage and glycosylation protein activities. Our study provides insights into population-specific novel genes for corneal curvature, and their pleiotropic effect in regulating eye size or conferring susceptibility to myopia

A 15-year review owef dengue hospitalizations in singapore: Reducing admissions without adverse consequences, 2003 to 2017

10.1371/journal.pntd.0007389PLoS Neglected Tropical Diseases135e000738

Investigation of a cluster of multi-drug resistant tuberculosis in a high-rise apartment block in Singapore

10.1016/j.ijid.2017.12.010International Journal of Infectious Diseases6746-5

Seroprevalence of antibodies against chikungunya virus in Singapore resident adult population

10.1371/journal.pntd.0006163PLoS Neglected Tropical Diseases1112e000616

Detection of viral respiratory pathogens in mild and severe acute respiratory infections in Singapore

10.1038/srep42963Scientific Reports74296

Imported monkeypox, Singapore

10.3201/eid2608.191387Emerging Infectious Diseases2681826-183