Cognitive Disease, Metabolic Disease, and Inflammation in the Honolulu Asia Aging Study: Connnecting the Dots between Insulin Resistance, Type 2 Diabetes, Alzheimer's Disease, Dementia, and Fibrinogen.

Ph.D. Thesis. University of Hawaiʻi at Mānoa 2017

Finite-volume Hamiltonian method for coupled channel interactions in lattice QCD

Within a multi-channel formulation of $\pi\pi$ scattering, we investigate the use of the finite-volume Hamiltonian approach to resolve scattering observables from lattice QCD spectra. The asymptotic matching of the well-known L\"uscher formalism encodes a unique finite-volume spectrum. Nevertheless, in many practical situations, such as coupled-channel systems, it is advantageous to interpolate isolated lattice spectra in order to extract physical scattering parameters. Here we study the use of the Hamiltonian framework as a parameterisation that can be fit directly to lattice spectra. We find that with a modest amount of lattice data, the scattering parameters can be reproduced rather well, with only a minor degree of model dependence.Comment: 25 pages, 16 figure

Automatic estimation of flux distributions of astrophysical source populations

In astrophysics a common goal is to infer the flux distribution of populations of scientifically interesting objects such as pulsars or supernovae. In practice, inference for the flux distribution is often conducted using the cumulative distribution of the number of sources detected at a given sensitivity. The resulting "$\log(N>S)$-$\log (S)$" relationship can be used to compare and evaluate theoretical models for source populations and their evolution. Under restrictive assumptions the relationship should be linear. In practice, however, when simple theoretical models fail, it is common for astrophysicists to use prespecified piecewise linear models. This paper proposes a methodology for estimating both the number and locations of "breakpoints" in astrophysical source populations that extends beyond existing work in this field. An important component of the proposed methodology is a new interwoven EM algorithm that computes parameter estimates. It is shown that in simple settings such estimates are asymptotically consistent despite the complex nature of the parameter space. Through simulation studies it is demonstrated that the proposed methodology is capable of accurately detecting structural breaks in a variety of parameter configurations. This paper concludes with an application of our methodology to the Chandra Deep Field North (CDFN) data set.Comment: Published in at http://dx.doi.org/10.1214/14-AOAS750 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org

Quartification with T' Flavor

In the simplest (non-quiver) unified theories, fermion families are often treated sequentially and a flavor symmetry may act similarly. As an alternative with non-sequential flavor symmetry, we consider a model based on the group (T'*Z_2)_global * [SU(3)^4]_local which combines the predictions of T' flavor symmetry with the features of a unified quiver gauge theory. The model accommodates the relationships between mixing angles separately for neutrinos, and for quarks, which have been previously predicted with T'. This quiver unification theory makes predictions of several additional gauge bosons and bifundamental fermions at the TeV scale.Comment: 8 pages, LaTex; added references and clarifie

Regge approach to charged-pion photoproduction at invariant energies above 2 GeV

A Regge model with absorptive corrections is employed in a global analysis of the world data on positive and negative pion photoproduction for photon energies from 3 to 8 GeV. In this region resonance contributions are expected to be negligible so that the available experimental information on differential cross sections and single polarization observables at -t \leq 2 GeV^2 allows us to determine the non-resonant part of the reaction amplitude reliably. The model amplitude is then used to predict observables for photon energies below 3 GeV. Differences between our predictions and data in this energy region are systematically examined as possible signals for the presence of excited baryons. We find that the data available for the polarized photon asymmetry show promising resonance signatures at invariant energies around 2 GeV. With regard to differential cross sections the analysis of negative pion photoproduction data, obtained recently at JLab, indicates likewise the presence of resonance structures around 2 GeVComment: misprint in Table 3 corrected; reference adde