B-L-violating Masses in Softly Broken Supersymmetry

We prove a general low-energy theorem establishing a generic relation between the neutrino Majorana mass and the superpartner sneutrino B-L-violating "Majorana"-like mass term. The theorem states that, if one of these two quantities is non-zero the other one is also non-zero and, vice versa, if one of them vanishes the other vanishes, too. The theorem is a consequence of the underlying supersymmetry (SUSY) and valid for any realistic gauge model with weak scale softly broken SUSY.Comment: 7 pages, Latex, 1 Postscript figur

An evaluation of combined geophysical and geotechnical methods to characterize beach thickness

Beaches provide sediment stores and have an important role in the development of the coastline in response to climate change. Quantification of beach thickness and volume is required to assess coastal sediment transport budgets. Therefore, portable, rapid, non-invasive techniques are required to evaluate thickness where environmental sensitivities exclude invasive methods. Site methods and data are described for a toolbox of electrical, electromagnetic, seismic and mechanical based techniques that were evaluated at a coastal site at Easington, Yorkshire. Geophysical and geotechnical properties are shown to be dependent upon moisture content, porosity and lithology of the beach and the morphology of the beach–platform interface. Thickness interpretation, using an inexpensive geographic information system to integrate data, allowed these controls and relationships to be understood. Guidelines for efficient site practices, based upon this case history including procedures and techniques, are presented using a systematic approach. Field results indicated that a mixed sand and gravel beach is highly variable and cannot be represented in models as a homogeneous layer of variable thickness overlying a bedrock half-space

Physical Origin, Evolution and Observational Signature of Diffused Antiworld

The existence of macroscopic regions with antibaryon excess in the baryon asymmetric Universe with general baryon excess is the possible consequence of practically all models of baryosynthesis. Diffusion of matter and antimatter to the border of antimatter domains defines the minimal scale of the antimatter domains surviving to the present time. A model of diffused antiworld is considered, in which the density within the surviving antimatter domains is too low to form gravitationally bound objects. The possibility to test this model by measurements of cosmic gamma ray fluxes is discussed. The expected gamma ray flux is found to be acceptable for modern cosmic gamma ray detectors and for those planned for the near future.Comment: 9 page

Nonconcentration of energy for a semilinear Skyrme model

We continue our investigation of a model introduced by Adkins and Nappi, in which omega mesons stabilize chiral solitons. The aim of this article is to show that the energy associated to equivariant solutions does not concentrate.Comment: 12 pages, 2 figure

Quantum Monte Carlo treatment of elastic exciton-exciton scattering

We calculate cross sections for low energy elastic exciton-exciton scattering within the effective mass approximation. Unlike previous theoretical approaches, we give a complete, non-perturbative treatment of the four-particle scattering problem. Diffusion Monte Carlo is used to calculate the essentially exact energies of scattering states, from which phase shifts are determined. For the case of equal-mass electrons and holes, which is equivalent to positronium-positronium scattering, we find a_s = 2.1 a_x for scattering of singlet-excitons and a_s= 1.5 a_x for triplet-excitons, where a_x is the excitonic radius. The spin dependence of the cross sections arises from the spatial exchange symmetry of the scattering wavefunctions. A significant triplet-triplet to singlet-singlet scattering process is found, which is similar to reported effects in recent experiments and theory for excitons in quantum wells. We also show that the scattering length can change sign and diverge for some values of the mass ratio m_h/m_e, an effect not seen in previous perturbative treatments.Comment: 6 pages, 6 figures. Revision has updated figures, improved paper structure, some minor correction

Owl and Lizard: Patterns of Head Pose and Eye Pose in Driver Gaze Classification

Accurate, robust, inexpensive gaze tracking in the car can help keep a driver safe by facilitating the more effective study of how to improve (1) vehicle interfaces and (2) the design of future Advanced Driver Assistance Systems. In this paper, we estimate head pose and eye pose from monocular video using methods developed extensively in prior work and ask two new interesting questions. First, how much better can we classify driver gaze using head and eye pose versus just using head pose? Second, are there individual-specific gaze strategies that strongly correlate with how much gaze classification improves with the addition of eye pose information? We answer these questions by evaluating data drawn from an on-road study of 40 drivers. The main insight of the paper is conveyed through the analogy of an "owl" and "lizard" which describes the degree to which the eyes and the head move when shifting gaze. When the head moves a lot ("owl"), not much classification improvement is attained by estimating eye pose on top of head pose. On the other hand, when the head stays still and only the eyes move ("lizard"), classification accuracy increases significantly from adding in eye pose. We characterize how that accuracy varies between people, gaze strategies, and gaze regions.Comment: Accepted for Publication in IET Computer Vision. arXiv admin note: text overlap with arXiv:1507.0476

Differential attainment at MRCS according to gender, ethnicity, age and socioeconomic factors : A retrospective cohort study

Open access via Sage agreement Acknowledgements The authors would like to acknowledge Iain Targett at the Royal College of Surgeons of England, for his help with data collection and John Hines and Gregory Ayre from the Intercollegiate Committee for Basic Surgical Examinations for their support during this project. Our thanks to members of the UKMED Research Group who provided useful feedback on an earlier version of this manuscript, and whose comments helped refine the paper. The authors would also like to acknowledge Daniel Smith for his help with the UKMED database. Data Source: UK Medical Education Database (“UKMED”). UKMEDP043 extract generated on 25 July 2018. We are grateful to UKMED for the use of these data. However, UKMED bears no responsibility for their analysis or interpretation. The data include information derived from that collected by the Higher Education Statistics Agency (“HESA”) Limited and provided to the GMC (“HESA Data”). Source: HESA Student Records 2007/2008 to 2015/2016. Copyright Higher Education Statistics Agency Limited. The Higher Education Statistics Agency Limited makes no warranty as to the accuracy of the HESA Data, cannot accept responsibility for any inferences or conclusions derived by third parties from data or other Information supplied by it. The dataset used in this study was acquired from the UK Medical Education Database and is held in Safe Haven. All counts have been rounded to the nearest 5 according to HESA data standards to ensure person-level anonymity, as per UKMED policy. Data access requests must be made to UKMED. Full information for applications can be found at https://www.ukmed.ac.uk.Peer reviewedPublisher PD

The low-energy phase-only action in a superconductor: a comparison with the XY model

The derivation of the effective theory for the phase degrees of freedom in a superconductor is still, to some extent, an open issue. It is commonly assumed that the classical XY model and its quantum generalizations can be exploited as effective phase-only models. In the quantum regime, however, this assumption leads to spurious results, such as the violation of the Galilean invariance in the continuum model. Starting from a general microscopic model, in this paper we explicitly derive the effective low-energy theory for the phase, up to fourth-order terms. This expansion allows us to properly take into account dynamic effects beyond the Gaussian level, both in the continuum and in the lattice model. After evaluating the one-loop correction to the superfluid density we critically discuss the qualitative and quantitative differences between the results obtained within the quantum XY model and within the correct low-energy theory, both in the case of s-wave and d-wave symmetry of the superconducting order parameter. Specifically, we find dynamic anharmonic vertices, which are absent in the quantum XY model, and are crucial to restore Galilean invariance in the continuum model. As far as the more realistic lattice model is concerned, in the weak-to-intermediate-coupling regime we find that the phase-fluctuation effects are quantitatively reduced with respect to the XY model. On the other hand, in the strong-coupling regime we show that the correspondence between the microscopically derived action and the quantum XY model is recovered, except for the low-density regime.Comment: 29 pages, 11 figures. Slightly revised presentation, accepted for publication in Phys. Rev.

The small fiber neuropathy NaV1.7 I228M mutation: impaired neurite integrity via bioenergetic and mitotoxic mechanisms, and protection by dexpramipexole

Gain-of-function variants in voltage-gated sodium channel NaV1.7 that increase firing frequency and spontaneous firing of dorsal root ganglion (DRG) neurons have recently been identified in 5-10% of patients with idiopathic small fiber neuropathy (I-SFN). Our previous in vitro observations suggest that enhanced sodium channel activity can contribute to a decrease in length of peripheral sensory axons. We have hypothesized that sustained sodium influx due to the expression of SFN-associated sodium channel variants may trigger an energetic deficit in neurons that contributes to degeneration and loss of nerve fibers in SFN. Using an ATP FRET biosensor, we now demonstrate reduced steady-state levels of ATP and markedly faster ATP decay in response to membrane depolarization in cultured DRG neurons expressing an SFN-associated variant NaV1.7, I228M, compared with wild-type neurons. We also observed that I228M neurons show a significant reduction in mitochondrial density and size, indicating dysfunctional mitochondria and a reduced bioenergetic capacity. Finally, we report that exposure to dexpramipexole, a drug that improves mitochondrial energy metabolism, increases the neurite length of I228M-expressing neurons. Our data suggest that expression of gain-of-function variants of NaV1.7 can damage mitochondria and compromise cellular capacity for ATP production. The resulting bioenergetic crisis can consequently contribute to loss of axons in SFN. We suggest that, in addition to interventions that reduce ionic disturbance caused by mutant NaV1.7 channels, an alternative therapeutic strategy might target the bioenergetic burden and mitochondrial damage that occur in SFN associated with NaV1.7 gain-of-function mutations.NEW & NOTEWORTHY Sodium channel NaV1.7 mutations that increase dorsal root ganglion (DRG) neuron excitability have been identified in small fiber neuropathy (SFN). We demonstrate reduced steady-state ATP levels, faster depolarization-evoked ATP decay, and reduced mitochondrial density and size in cultured DRG neurons expressing SFN-associated variant NaV1.7 I228M. Dexpramipexole, which improves mitochondrial energy metabolism, has a protective effect. Because gain-of-function NaV1.7 variants can compromise bioenergetics, therapeutic strategies that target bioenergetic burden and mitochondrial damage merit study in SFN