Chaos in the segments from Korean traditional singing and western singing

We investigate the time series of the segments from a Korean traditional song ``Gwansanyungma'' and a western song ``La Mamma Morta'' using chaotic analysis techniques. It is found that the phase portrait in the reconstructed state space of the time series of the segment from the Korean traditional song has a more complex structure in comparison with the segment from the western songs. The segment from the Korean traditional song has the correlation dimension 4.4 and two positive Lyapunov exponents which show that the dynamic related to the Korean traditional song is a high dimensional hyperchaotic process. On the other hand, the segment from the western song with only one positive Lyapunov exponent and the correlation dimension 2.5 exhibits low dimensional chaotic behavior.Comment: 23 pages including 10 eps figures, latex, to appear in J. Acoust. Soc. A

Iterative Soft Decoding Algorithm for DNA Storage Using Quality Score and Redecoding

Ever since deoxyribonucleic acid (DNA) was considered as a next-generation data-storage medium, lots of research efforts have been made to correct errors occurred during the synthesis, storage, and sequencing processes using error correcting codes (ECCs). Previous works on recovering the data from the sequenced DNA pool with errors have utilized hard decoding algorithms based on a majority decision rule. To improve the correction capability of ECCs and robustness of the DNA storage system, we propose a new iterative soft decoding algorithm, where soft information is obtained from FASTQ files and channel statistics. In particular, we propose a new formula for log-likelihood ratio (LLR) calculation using quality scores (Q-scores) and a redecoding method which may be suitable for the error correction and detection in the DNA sequencing area. Based on the widely adopted encoding scheme of the fountain code structure proposed by Erlich et al., we use three different sets of sequenced data to show consistency for the performance evaluation. The proposed soft decoding algorithm gives 2.3% ~ 7.0% improvement of the reading number reduction compared to the state-of-the-art decoding method and it is shown that it can deal with erroneous sequenced oligo reads with insertion and deletion errors

THE EFFECT OF SHOES ON KNEE KINETICS AND ANTERIOR TIBIAL TRANSLATION DURING SINGLE-LEG LANDING

The purpose of this study was to compare how knee kinematics and kinetics are influenced during single-leg landing in shod condition compared to barefoot condition. We hypothesized that the anterior tibial translation (ATT) and utilized coefficient of friction (uCoF) are greater in shod landing. Ten male subjects performed single-leg landing from a 0.3-m-high platform using their self-selected dominant lower limb under shod and barefoot condition. A force plate and a motion capture system were used for measuring ground reaction force and capturing kinematics data, respectively. The shod condition showed a significant higher ATT (p = 0.011) and uCoF (p = 0.022) at 30° flexion than barefoot condition. These findings would be considered as one of evidence that high shoe-surface friction increase ACL injury risks due to high ATT at extended knee position

Fully Quantized Always-on Face Detector Considering Mobile Image Sensors

Despite significant research on lightweight deep neural networks (DNNs) designed for edge devices, the current face detectors do not fully meet the requirements for "intelligent" CMOS image sensors (iCISs) integrated with embedded DNNs. These sensors are essential in various practical applications, such as energy-efficient mobile phones and surveillance systems with always-on capabilities. One noteworthy limitation is the absence of suitable face detectors for the always-on scenario, a crucial aspect of image sensor-level applications. These detectors must operate directly with sensor RAW data before the image signal processor (ISP) takes over. This gap poses a significant challenge in achieving optimal performance in such scenarios. Further research and development are necessary to bridge this gap and fully leverage the potential of iCIS applications. In this study, we aim to bridge the gap by exploring extremely low-bit lightweight face detectors, focusing on the always-on face detection scenario for mobile image sensor applications. To achieve this, our proposed model utilizes sensor-aware synthetic RAW inputs, simulating always-on face detection processed "before" the ISP chain. Our approach employs ternary (-1, 0, 1) weights for potential implementations in image sensors, resulting in a relatively simple network architecture with shallow layers and extremely low-bitwidth. Our method demonstrates reasonable face detection performance and excellent efficiency in simulation studies, offering promising possibilities for practical always-on face detectors in real-world applications.Comment: Accepted to ICCV 2023 Workshop on Low-Bit Quantized Neural Networks (LBQNN), Ora

Combined treatment with silibinin and either sorafenib or gefitinib enhances their growth-inhibiting effects in hepatocellular carcinoma cells

Background/AimsSilibinin, the main component of silymarin, is used as a hepatoprotectant and exhibits anticancer effects against various cancer cells. This study evaluated the effects of a combination of silibinin with either gefitinib or sorafenib on hepatocellular carcinoma (HCC) cells.MethodsSeveral different human HCC cell lines were used to test the growth-inhibiting effects and cell toxicity of silibinin both alone and in combination with either gefitinib or sorafenib. The cell viability and growth inhibition were assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, trypan blue staining, and a colony-forming assay. Furthermore, changes in epidermal growth factor receptor (EGFR)-related signals were evaluated by Western blot analysis.ResultsGefitinib, sorafenib, and silibinin individually exhibited dose-dependent antiproliferative effects on HCC cells. Combined treatment with silibinin enhanced the gefitinib-induced growth-inhibiting effects in some HCC cell lines. The combination effect of gefitinib and silibinin was synergistic in the SNU761 cell line, but was only additive in the Huh-BAT cell line. The combination effect may be attributable to inhibition of EGFR-dependent Akt signaling. Enhanced growth-inhibiting effects were also observed in HCC cells treated with a combination of sorafenib and silibinin.ConclusionsCombined treatment with silibinin enhanced the growth-inhibiting effects of both gefitinib and sorafenib. Therefore, the combination of silibinin with either sorafenib or gefitinib could be a useful treatment approach for HCC in the future

An Updated Review of Tyrosinase Inhibitors

Tyrosinase is a multifunctional, glycosylated, and copper-containing oxidase, which catalyzes the first two steps in mammalian melanogenesis and is responsible for enzymatic browning reactions in damaged fruits during post-harvest handling and processing. Neither hyperpigmentation in human skin nor enzymatic browning in fruits are desirable. These phenomena have encouraged researchers to seek new potent tyrosinase inhibitors for use in foods and cosmetics. This article surveys tyrosinase inhibitors newly discovered from natural and synthetic sources. The inhibitory strength is compared with that of a standard inhibitor, kojic acid, and their inhibitory mechanisms are discussed

Nutritional Status of Vitamin D and the Effect of Vitamin D Supplementation in Korean Breast-fed Infants

We investigated the vitamin D status and the effect of vitamin D supplementation in Korean breast-fed infants. The healthy term newborns were divided into 3 groups; A, formula-fed; B, breast-fed only; S, breast-fed with vitamin D supplementation. We measured serum concentrations of vitamin D (25OHD3), calcium (Ca), phosphorus (P), alkaline phosphatase (AP), intact parathyroid hormone (iPTH) and bone mineral density (BMD) at 6 and 12 months of age. Using questionnaires, average duration of sun-light exposure and dietary intake of vitamin D, Ca and P were obtained. At 6 and 12 months of age, 25OHD3 was significantly higher in group S than in group B (P<0.001). iPTH was significantly lower in group S than in group B at 6 months (P=0.001), but did not differ at 12 months. Regardless of vitamin D supplementation, BMD was lower in group B and S than in group A (P<0.05). Total intake of vitamin D differed among 3 groups (P<0.001, A>S>B), but total intake of Ca and P were higher in group A than in group B and S (P<0.001). In conclusion, breast-fed infants show lower vitamin D status and bone mineralization than formula-fed infants. Vitamin D supplementation (200 IU/day) in breast-fed infants increases serum 25-OH vitamin D3, but not bone mineral density