MHD stability and mode locking in pre-disruptive plasmas on tore supra

SIGLEAvailable at INIST (FR), Document Supply Service, under shelf-number : RM 1162 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc

Current diffusion and flux consumption in tore supra

Available at INIST (FR), Document Supply Service, under shelf-number : RM 1277 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueSIGLEFRFranc

The ergodic divertor a way to prevent major disruptions

Communication presentee a IAEA technical committee meeting on the avoidance and control of tokamak distuptions, Culham (UK), 10-12 Sept. 1991Available at INIST (FR), Document Supply Service, under shelf-number : RM 1490 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueSIGLEFRFranc

Sodium Oxybate for Alcohol Dependence: A Network Meta-Regression Analysis Considering Population Severity at Baseline and Treatment Duration

International audienceAIMS: The estimated effect of sodium oxybate (SMO) in the treatment of alcohol dependence is heterogeneous. Population severity and treatment duration have been identified as potential effect modifiers. Population severity distinguishes heavy drinking patients with <14 days of abstinence before treatment initiation (high-severity population) from other patients (mild-severity population). Treatment duration reflects the planned treatment duration. This study aimed to systematically investigate the effect of these potential effect moderators on SMO efficacy in alcohol-dependent patients. METHODS: Network meta-regression allows for testing potential effect modifiers. It was selected to investigate the effect of the above factors on SMO efficacy defined as continuous abstinence (abstinence rate) and the percentage of days abstinent (PDA). Randomized controlled trials for alcohol dependence with at least one SMO group conducted in high-severity and mild-severity populations were assigned to a high-severity and mild-severity group of studies, respectively. RESULTS: Eight studies (1082 patients) were retained: four in the high-severity group and four in the mild-severity group. The high-severity group was associated with larger SMO effect sizes than the mild-severity group: abstinence rate risk ratio (RR) 3.16, P = 0.004; PDA +26.9%, P < 0.001. For PDA, longer treatment duration was associated with larger SMO effect size: +11.3% per extra month, P < 0.001. In the high-severity group, SMO showed benefit: abstinence rate RR 2.91, P = 0.03; PDA +16.9%, P < 0.001. In the mild-severity group, SMO showed benefit only in PDA for longer treatment duration: +23.9%, P < 0.001. CONCLUSIONS: In the retained studies with alcohol-dependent patients, high-severity population and longer treatment duration were associated with larger SMO effect sizes

Lower Hybrid Current Drive in Tore Supra and Jet

Recent Lower Hybrid Current Drive (LHCD) experiments in TORE SUPRA and JET are reported. Large multijunction launchers have allowed the coupling of 5 MW to the plasma for several seconds with a maximum of 3.8 kw/cm2. Measurements of the scattering matrices of the antennae show good agreement with theory. The current drive efficiency in TORE SUPRA is about 0.2 x 10(20) Am-2/W with LH power alone and reaches 0.4 x 10(20) Am-2/W in JET thanks to a high volume-averaged electron temperature (1.9 keV) and also to a synergy between Lower Hybrid and Fast Magnetosonic Waves. At N(e)BAR = 1.5 x 10(19) m-3 in TORE SUPRA, sawteeth are suppressed and m = 1 MHD oscillations the frequency of which clearly depends on the amount of LH power are observed on soft x-rays, and also on non-thermal ECE. In JET ICRH produced sawtooth-free periods are extended by the application of LHCD (2.9 s. with 4 MW ICRH) and current profile broadening has been clearly observed consistent with off-axis fast electron populations. LH power modulation experiments performed in TORE SUPRA at N(e)BAR = 4 x 10(19) m-3 show a delayed central electron heating despite the off-axis creation of suprathermal electrons, thus ruling out the possibility of a direct heating through central wave absorption. A possible explanation in terms of anomlous fast electron transport and classical slowing down would yield a diffusion coefficient of the order of 10 m2/s for the fast electrons. Other interpretations such as an anomalous heat pinch or a central confinement enhancement cannot be excluded. Finally, successful pellet fuelling of a partially LH driven plasma was obtained in TORE SUPRA, 28 successive pellets allowing the density to rise to N(e)BAR = 4 x 10(19) m-3. This could be achieved by switching the LH power off for 90 ms before each pellet injection, i.e. without modifying significantly the current density profile