It is time to prepare mental health services to attend to migrants and refugees

Univ Fed Sao Paulo UNIFESP, Dept Psiquiatria, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Programa Posgrad Psiquiatria & Psicol Med, Sao Paulo, SP, BrazilUniv Fed Sao Paulo UNIFESP, Dept Psiquiatria, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Programa Posgrad Psiquiatria & Psicol Med, Sao Paulo, SP, BrazilWeb of Scienc

Stress, trauma, and posttraumatic stress disorder in migrants: a comprehensive review

Objective: There is growing evidence supporting the association between migration and posttraumatic stress disorder (PTSD). Considering the growing population of migrants and the particularities of providing culturally sensitive mental health care for these persons, clinicians should be kept up to date with the latest information regarding this topic. The objective of this study was to critically review the literature regarding migration, trauma and PTSD, and mental health services. Methods: The PubMed, SciELO, LILACS, and ISI Web of Science databases were searched for articles published in Portuguese, English, Spanish, or French, and indexed from inception to 2017. The following keywords were used: migration, mental health, mental health services, stress, posttraumatic stress disorder, and trauma. Results: Migration is associated with specific stressors, mainly related to the migratory experience and to the necessary process of acculturation occurring in adaptation to the host country. These major stressors have potential consequences in many areas, including mental health. The prevalence of PTSD among migrants is very high (47%), especially among refugees, who experience it at nearly twice the rate of migrant workers. Conclusions: Mental health professionals must be trained to recognize and provide appropriate care for posttraumatic and/or stress-related disorders among migrants.Univ Fed Sao Paulo UNIFESP, Dept Psiquiatria, Sao Paulo, SP, BrazilUniv Fed Sao Paulo UNIFESP, Dept Psiquiatria, Sao Paulo, SP, BrazilWeb of Scienc

A deletion in GDF7 is associated with a heritable forebrain commissural malformation concurrent with ventriculomegaly and interhemispheric cysts in cats

Publisher Copyright: © 2020 by the authors.An inherited neurologic syndrome in a family of mixed-breed Oriental cats has been characterized as forebrain commissural malformation, concurrent with ventriculomegaly and interhemispheric cysts. However, the genetic basis for this autosomal recessive syndrome in cats is unknown. Forty-three cats were genotyped on the Illumina Infinium Feline 63K iSelect DNA Array and used for analyses. Genome-wide association studies, including a sib-transmission disequilibrium test and a case-control association analysis, and homozygosity mapping, identified a critical region on cat chromosome A3. Short-read whole genome sequencing was completed for a cat trio segregating with the syndrome. A homozygous 7 bp deletion in growth differentiation factor 7 (GDF7) (c.221_227delGCCGCGC [p.Arg74Profs]) was identified in affected cats, by comparison to the 99 Lives Cat variant dataset, validated using Sanger sequencing and genotyped by fragment analyses. This variant was not identified in 192 unaffected cats in the 99 Lives dataset. The variant segregated concordantly in an extended pedigree. In mice, GDF7 mRNA is expressed within the roof plate when commissural axons initiate ventrally-directed growth. This finding emphasized the importance of GDF7 in the neurodevelopmental process in the mammalian brain. A genetic test can be developed for use by cat breeders to eradicate this variant.Peer reviewe

Etude des différents facteurs de mortalité des huîtres en baie de Quiberon

This training report (Intechmer-Ifremer) describes the first results of the program "Risco", on the causes of oysters mortalities in the bay of Quiberon (56, France). 3 parts of the 2010 research are presented : (1) the sonar campain with the ship "Haliotis", for identifying the nature of the bottom and benthic fauna, (2) the video campain, which allowed to precise the spatial distribution of oysters and crepidulas densities, (3) the experiment conducted in 15 stations of the bay, so as to evaluate the influence of sediment and predators on oysters mortalities (1 year and 2 years old oysters). The first results are presented on the predation exerted on oysters by starfish and oyster drills.Ce rapport de stage Intechmer-Ifremer décrit la mise en place et les premiers résultats du programme "Risco", sur les causes de mortalité d'huîtres en baie de Quiberon (56, France). 3 volets de l'étude de 2010 sont présentés : (1) la campagne sonar de l'Haliotis, destinée à identifier la nature du fond et des peuplements benthiques, (2) la campagne de vidéo-sous marine qui a permis de préciser la répartition et les densités d'huîtres et de crépidules, (3) l'expérience menée en 15 stations de la baie, destinée à évaluer l'influence du sédiment et des prédateurs sur la mortalité d'huîtres (1 an et 2 ans). Les premiers résultats portant notamment sur la prédation par étoiles de mer et bigorneaux perceurs sont présentés

A Progressão Multi-Sistêmica Do Transtorno Bipolar: Dos Fatores De Risco À Intervenção

Objective: Comprehensively Review Studies Evaluating Factors Associated With Adherence To Treatment In Bipolar Disorder (Bd), As Well As The Results Of Interventions Developed To Enhance Adherence In This Population. Methods: The Following Search Engines Were Consulted: Pubmed, Scielo, Lilacs And Psycinfo. The Keywords Used Were ``Bipolar Disorder"", ``Factor"", ``Adherence"", ``Nonadherence"", ``Compliance"" And ``Intervention"". In Addition, References List Of Selected Studies Were Consulted Searching For Relevant Articles. Results: Adherence Has Been Defined In Various Ways, With Some Considering Adherence Vs. Nonadherence, And Other Including A ``Partial"" Adherence Measure. In Addition, Methods To Assess Adherence Differ For Each Study. Several Factors Were Related To Poor Adherence, Including Patient-Related Factors (E.G. Younger Age, Male Gender, Low Level Of Education, Alcohol And Drugs Comorbidity), Disorder-Related Factors (E.G. Younger Age Of Onset, Severity Of Bd, Insight And Lack Of Awareness OfO Objetivo Geral Da Tese É Acrescentar, De Vários Ângulos, No Campo De Intervenção No Tb, Todos Ligados A Entender E A Intervir Da Maneira Mais Estratégica, A Fim De Evitar A Progressão Multissistêmica Do Curso. O Primeiro Artigo Apresenta Uma Revisão Dos Fatores De Não Adesão Ao Tratamento No Tb De Largo Espectro, Incluindo Os Diferentes Tipos Ou Estratégias De Intervenções Eficazes Focalizadas Na Adesão. É Baseado No Modelo Da Psicoeducação Canadense, Focando Em Identificar Os Possíveis Alvos De Intervenções Psicossociais Em Diferentes Níveis (Individuais E Mais Amplos), Ou Seja, Os Fatores Modificáveis De Não Adesão Ao Tratamento. O Segundo Artigo Avalia A Relação Entre Os Maus-Tratos Na Infância E O Imc, Um Dos Medidores De Progressão, De Acordo Com Diferentes Estágios De Progressão Do Tb. O Primeiro Objetivo Foi Determinar Se Exista Uma Relação Positiva Específica Entre Uma História De Maus-Tratos E O Imc Em Uma Amostra De Pacientes Brasileiros Com Tb. O Segundo Objetivo Foi Investigar Se A Relação É DifDados abertos - Sucupira - Teses e dissertações (2018