Parents’ perceptions of children’s psychosocial adaptation during the COVID-19 pandemic in Québec: Comparison with gifted and non-gifted children

Studies conducted in French Canadian schools following the COVID-19 lockdown report that children in a pandemic might have difficulties adapting. Gifted and twice-exceptional children—who might present special needs in this situation—could have different levels of psychosocial adaptation and mental-health needs than other children. This study assessed the psychosocial adaptation of gifted and twice-exceptional children and compared the adaptation levels of these individuals to those of non-identified gifted children. The results show that 62.5% of the gifted children had generally coped well with pandemic conditions, as did the non-identified gifted children (73.9%). Conversely, 59.5% of twice-exceptional children presented difficulties in adapting to the pandemic situation regardless of subscale (e.g., depression, anxiety, aggressiveness). Accordingly, they exhibited more internalized (p \u3c .001) and externalized (p \u3c .001) behaviors than the non-identified gifted children and more externalized behaviors than the gifted (p = .014). The children in the gifted sample exhibited age and gender differences, with the youngest showing more externalized difficulties than the older children and the boys showing more externalized behaviors than the girls. Taken together, these results suggest that giftedness is not an indication of a propensity for developing skills for adapting to pandemic conditions. It appears that having a neurodevelopmental condition associated with giftedness is more significant because the twice-exceptional children had more difficulty adapting than the non-identified gifted and, on some subscales, than the gifted

Regards d’enseignants québécois sur les élèves doués : points de vue diversifiés

This study examines teachers’ perceptions of gifted students in their class, in a Quebec school service centre, and the influence of personal and contextual variables. The sample consists of 21 primary school teachers (18 women and 3 men). After the lexical analysis carried out with the Alceste software, four specific classes of statements emerge from the teachers’ discourse. In addition, age, teaching cycle, type of class, number of years of experience, involvement in an intervention plan and experience with giftedness predict the heterogeneity of the perceptions of teachers towards giftedness. The results suggest more traditional and stereotypical perceptions of giftedness by teachers. Keywords: perceptions, representations, teachers, giftedness, characteristics, high potential, lexical analysisCette étude s’intéresse aux perceptions des enseignants concernant les élèves doués de leur classe, dans un centre de services scolaire québécois, et à l’influence de certaines variables personnelles et contextuelles sur ces perceptions. L’échantillon se compose de 21 enseignants du primaire (18 femmes et 3 hommes). À l’issue de l’analyse lexicale réalisée avec le logiciel Alceste, quatre classes d’énoncés spécifiques se dégagent du discours des enseignants. L’âge, le cycle d’enseignement, le type de classe, le nombre d’années d’expérience, l’implication dans un plan d’intervention et l’expérience envers la douance constituent des facteurs explicatifs de l’hétérogénéité des perceptions des enseignants envers la douance. Les résultats portent également à croire que des perceptions plus traditionnelles et stéréotypées de la douance persistent chez certains enseignants. Mots-clés : perceptions, représentations, enseignants, douance, caractéristiques, haut potentiel, analyse lexical

The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage.

Site-specific histone ubiquitylation plays a central role in orchestrating the response to DNA double-strand breaks (DSBs). DSBs elicit a cascade of events controlled by the ubiquitin ligase RNF168, which promotes the accumulation of repair factors such as 53BP1 and BRCA1 on the chromatin flanking the break site. RNF168 also promotes its own accumulation, and that of its paralog RNF169, but how they recognize ubiquitylated chromatin is unknown. Using methyl-TROSY solution NMR spectroscopy and molecular dynamics simulations, we present an atomic resolution model of human RNF169 binding to a ubiquitylated nucleosome, and validate it by electron cryomicroscopy. We establish that RNF169 binds to ubiquitylated H2A-Lys13/Lys15 in a manner that involves its canonical ubiquitin-binding helix and a pair of arginine-rich motifs that interact with the nucleosome acidic patch. This three-pronged interaction mechanism is distinct from that by which 53BP1 binds to ubiquitylated H2A-Lys15 highlighting the diversity in site-specific recognition of ubiquitylated nucleosomes

Potential of Core-Collapse Supernova Neutrino Detection at JUNO

JUNO is an underground neutrino observatory under construction in Jiangmen, China. It uses 20kton liquid scintillator as target, which enables it to detect supernova burst neutrinos of a large statistics for the next galactic core-collapse supernova (CCSN) and also pre-supernova neutrinos from the nearby CCSN progenitors. All flavors of supernova burst neutrinos can be detected by JUNO via several interaction channels, including inverse beta decay, elastic scattering on electron and proton, interactions on C12 nuclei, etc. This retains the possibility for JUNO to reconstruct the energy spectra of supernova burst neutrinos of all flavors. The real time monitoring systems based on FPGA and DAQ are under development in JUNO, which allow prompt alert and trigger-less data acquisition of CCSN events. The alert performances of both monitoring systems have been thoroughly studied using simulations. Moreover, once a CCSN is tagged, the system can give fast characterizations, such as directionality and light curve

Detection of the Diffuse Supernova Neutrino Background with JUNO

As an underground multi-purpose neutrino detector with 20 kton liquid scintillator, Jiangmen Underground Neutrino Observatory (JUNO) is competitive with and complementary to the water-Cherenkov detectors on the search for the diffuse supernova neutrino background (DSNB). Typical supernova models predict 2-4 events per year within the optimal observation window in the JUNO detector. The dominant background is from the neutral-current (NC) interaction of atmospheric neutrinos with 12C nuclei, which surpasses the DSNB by more than one order of magnitude. We evaluated the systematic uncertainty of NC background from the spread of a variety of data-driven models and further developed a method to determine NC background within 15\% with {\it{in}} {\it{situ}} measurements after ten years of running. Besides, the NC-like backgrounds can be effectively suppressed by the intrinsic pulse-shape discrimination (PSD) capabilities of liquid scintillators. In this talk, I will present in detail the improvements on NC background uncertainty evaluation, PSD discriminator development, and finally, the potential of DSNB sensitivity in JUNO

Real-time Monitoring for the Next Core-Collapse Supernova in JUNO

Core-collapse supernova (CCSN) is one of the most energetic astrophysical events in the Universe. The early and prompt detection of neutrinos before (pre-SN) and during the SN burst is a unique opportunity to realize the multi-messenger observation of the CCSN events. In this work, we describe the monitoring concept and present the sensitivity of the system to the pre-SN and SN neutrinos at the Jiangmen Underground Neutrino Observatory (JUNO), which is a 20 kton liquid scintillator detector under construction in South China. The real-time monitoring system is designed with both the prompt monitors on the electronic board and online monitors at the data acquisition stage, in order to ensure both the alert speed and alert coverage of progenitor stars. By assuming a false alert rate of 1 per year, this monitoring system can be sensitive to the pre-SN neutrinos up to the distance of about 1.6 (0.9) kpc and SN neutrinos up to about 370 (360) kpc for a progenitor mass of 30$M_{\odot}$ for the case of normal (inverted) mass ordering. The pointing ability of the CCSN is evaluated by using the accumulated event anisotropy of the inverse beta decay interactions from pre-SN or SN neutrinos, which, along with the early alert, can play important roles for the followup multi-messenger observations of the next Galactic or nearby extragalactic CCSN.Comment: 24 pages, 9 figure

La stimulation dopaminergique continue modifie-t-elle les symptômes nocturnes des parkinsoniens ?

Contexte : les troubles du sommeil de la maladie de Parkinson sont encore mal connus des cliniciens. Objectif principal : tester l'hypothèse que Ia stimulation dopaminergique discontinue favoriserait la survenue du syndrome des jambes sans repos (SJSR) nocturne. Objectifs secondaires : étudier les Troubles du sommeil en fonction du traitement reçu. Méthode : revue de la littérature et étude descriptive transversale des Troubles du sommeil à partir d'un questionnaire chez une population de parkinsoniens (72 patients) répartis suivant le traitement reçu. Résultats : La stimulation dopaminergique discontinue favorise le SJSR nocturne. Les patients sous stimulation dopaminergique semi-continue et continue ont une moins bonne qualité du sommeil. Les patients sous stimulation dopaminergique continue sont matinaux. Les troubles comportementaux en sommeil paradoxal et Ia somnolence ne varient pas en fonction du traitement. Conclusion : proposition d'un entretien dirigé sur les troubles du sommeil du parkinsonien.BREST-BU Médecine-Odontologie (290192102) / SudocPARIS-Bib. Serv.Santé Armées (751055204) / SudocSudocFranceF

Management options to reduce exposure to methyl mercury through the consumption of fish and fishery products by the French population

This paper presents an updated assessment of exposure in France to methyl mercury through the consumption of fish and fishery products, and proposes several management scenarios which could reduce this exposure through changes to fish contamination levels or fish consumption patterns. The exposure model was applied in line with previous methodological results [Tressou, J., Crépet, A., Bertail, P., Feinberg, M.H., Leblanc J.Ch., 2004a. Probabilistic exposure assessment to food chemicals based on extreme value theory: application to heavy metals from fish and sea products. Food Chem. Toxicol. 42, 1349-1358; Tressou, J., Leblanc, J.Ch., Feinberg, M., Bertail, P., 2004b. Statistical methodology to evaluate food exposure to a contaminant and influence of sanitary limits: application to ochratoxin A. Regul. Toxicol. Pharmacol. 40, 252-263] so as to obtain a realistic estimate of probability and confidence intervals (95% CI) concerning French consumers exposed to levels exceeding the revised fixed provisional tolerable weekly intake (PTWI) for methyl mercury of 1.6 microg/week/kg of body weight, established by the Joint FAO/WHO Expert Committee on Food Additives in 2003. The results showed that young children aged between 3 and 6 years old or 7 and 10 years old, and women of childbearing age were at the risk groups. With respect to these groups and according to the fish consumers patterns (consumers of predatory fish only or consumers of predatory and nonpredatory fish), the results suggested that strategies to diminish MeHg exposure by reducing the amount of predatory fish consumed would be more efficient in significantly decreasing the probability of exceeding the PTWI than the implementation of international standards

Probabilistic exposure assessment to food chemicals based on extreme value theory : application to heavy metals from fish and sea products

absen