Foot-operated cell-counter

Cell-counter for cell indices consists of a footboard with four pressure sensitive switches and an enclosure for the components and circuitry. This device increases the operators efficiency by reducing the number of required hand movements

Arbitrage, Equilibrium, and Nonsatiation

In his seminal paper on arbitrage and competitive equilibrium in unbounded exchange economies, Werner (Econometrica, 1987) proved the existence of a competitive equilibrium, under a price no-arbitrage condition, without assuming either local or global nonsatiation. Werner's existence result contrasts sharply with classical existence results for bounded exchange economies which require, at minimum, global nonsatiation at rational allocations. Why do unbounded exchange economies admit existence without local or global nonsatiation? This question is the focus of our paper. We make two main contributions to the theory of arbitrage and competitive equilibrium. First, we show that, in general, in unbounded exchange economies (for example, asset exchange economies allowing short sales), even if some agents' preferences are satiated, the absence of arbitrage is sufficient for the existence of competitive equilibria, as long as each agent who is satiated has a nonempty set of useful net trades - that is, as long as agents' preferences satisfy weak nonsatiation. Second, we provide a new approach to proving existence in unbounded exchange economies. The key step in our new approach is to transform the original economy to an economy satisfying global nonsatiation such that all equilibria of the transformed economy are equilibria of the original economy. What our approach makes clear is that it is precisely the condition of weak nonsatiation - a condition considerably weaker than local or global nonsatiation - that makes possible this transformation. Moreover, as we show via examples, without weak nonsatiation, existence fails.Arbitrage, Asset market equilibrium, Nonsatiation, Recession cones

Matching random colored points with rectangles

Let S ¿ [0, 1]2 be a set of n points, randomly and uniformly selected. Let R ¿ B be a random partition, or coloring, of S in which each point of S is included in R uniformly at random with probability 1/2. We study the random number M(n) of points of S that are covered by the rectangles of a maximum strong matching of S with axis-aligned rectangles. The matching consists of closed rectangles that cover exactly two points of S of the same color. A matching is strong if all its rectangles are pairwise disjoint. We prove that almost surely M(n) = 0.83 n for n large enough. Our approach is based on modeling a deterministic greedy matching algorithm, that runs over the random point set, as a Markov chain.Postprint (published version

Leukocyte function in COPD: clinical relevance and potential for drug therapy.

Chronic obstructive pulmonary disease (COPD) is a progressive lung condition affecting 10% of the global population over 45 years. Currently, there are no disease-modifying treatments, with current therapies treating only the symptoms of the disease. COPD is an inflammatory disease, with a high infiltration of leukocytes being found within the lung of COPD patients. These leukocytes, if not kept in check, damage the lung, leading to the pathophysiology associated with the disease. In this review, we focus on the main leukocytes found within the COPD lung, describing how the release of chemokines from the damaged epithelial lining recruits these cells into the lung. Once present, these cells become active and may be driven towards a more pro-inflammatory phenotype. These cells release their own subtypes of inflammatory mediators, growth factors and proteases which can all lead to airway remodeling, mucus hypersecretion and emphysema. Finally, we describe some of the current therapies and potential new targets that could be utilized to target aberrant leukocyte function in the COPD lung. Here, we focus on old therapies such as statins and corticosteroids, but also look at the emerging field of biologics describing those which have been tested in COPD already and potential new monoclonal antibodies which are under review

More oxygen during development enhanced flight performance but not thermal tolerance of Drosophila melanogaster

High temperatures can stress animals by raising the oxygen demand above the oxygen supply. Consequently, animals under hypoxia could be more sensitive to heating than those exposed to normoxia. Although support for this model has been limited to aquatic animals, oxygen supply might limit the heat tolerance of terrestrial animals during energetically demanding activities. We evaluated this model by studying the flight performance and heat tolerance of flies (Drosophila melanogaster) acclimated and tested at different concentrations of oxygen (12%, 21%, and 31%). We expected that flies raised at hypoxia would develop into adults that were more likely to fly under hypoxia than would flies raised at normoxia or hyperoxia. We also expected flies to benefit from greater oxygen supply during testing. These effects should have been most pronounced at high temperatures, which impair locomotor performance. Contrary to our expectations, we found little evidence that flies raised at hypoxia flew better when tested at hypoxia or tolerated extreme heat better than did flies raised at normoxia or hyperoxia. Instead, flies raised at higher oxygen levels performed better at all body temperatures and oxygen concentrations. Moreover, oxygen supply during testing had the greatest effect on flight performance at low temperature, rather than high temperature. Our results poorly support the hypothesis that oxygen supply limits performance at high temperatures, but do support the idea that hyperoxia during development improves performance of flies later in life

A simulation evaluation of a four-engine jet transport using engine thrust modulation for flightpath control

The use of throttle control laws to provide adequate flying qualities for flight path control in the event of a total loss of conventional flight control surface use was evaluated. The results are based on a simulation evaluation by transport research pilots of a B-720 transport with visual display. Throttle augmentation control laws can provide flight path control capable of landing a transport-type aircraft with up to moderate levels of turbulence. The throttle augmentation mode dramatically improves the pilots' ability to control flight path for the approach and landing flight condition using only throttle modulation. For light turbulence, the average Cooper-Harper pilot rating improved from unacceptable to acceptable (a pilot rating improvement of 4.5) in going from manual to augmented control. The low frequency response characteristics of the engines require a considerably different piloting technique. The various techniques used by the pilot resulted in considerable scatter in data. Many pilots readily adapted to a good piloting technique while some had difficulty. A new viable approach is shown to provide independent means of redundancy of transport aircraft flight path control

Learning through leisure recreation program for children who are visually impaired and blind

Includes bibliographical references.The student developed, directed, and coordinated a summer recreation program with the help of his supervisor at The Foundation for Blind Children in Scottsdale, Arizona; the responsibility of the coordinator was to design and implement the program within the context of the following educational and vocational domains: communication, orientation and mobility, self-help, social behavioral, personal hygiene, eating and food preparation, health and safety, and sports training. Several students enrolled in the program lacked the necessary skills in these areas and it was the intent of the coordinator to develop the skills of his students throughout the summer recreation program. The student's progress was evaluated as was the summer program. The student presented the information to Northern Illinois University by giving a presentation to an introductory vision course.B.S.Ed. (Bachelor of Science in Education

Extremal curves in nilpotent Lie groups

We classify extremal curves in free nilpotent Lie groups. The classification is obtained via an explicit integration of the adjoint equation in Pontryagin Maximum Principle. It turns out that abnormal extremals are precisely the horizontal curves contained in algebraic varieties of a specific type. We also extend the results to the nonfree case.Comment: 30 pages, final versio