3,749 research outputs found
A nonlinear fractional Rayleigh–Stokes equation under nonlocal integral conditions
In this paper, we study the fractional nonlinear Rayleigh–Stokes equation under nonlocal integral conditions, and the existence and uniqueness of the mild solution to our problem are considered. The ill-posedness of the mild solution to the problem recovering the initial value is also investigated. To tackle the ill-posedness, a regularized solution is constructed by the Fourier truncation method, and the convergence rate to the exact solution of this method is demonstrated.This research was funded by the National Research Foundation of Korea under grant number NRF-2020K1A3A1A05101625 and received the support from the Institute of Construction and Environmental Engineering at Seoul National University
Interaction of eukaryotic translation initiation factor 4G with the nuclear cap-binding complex provides a link between nuclear and cytoplasmic functions of the m7 guanosine cap
In eukaryotes the majority of mRNAs have an m7G cap that is added cotranscriptionally and that plays an important role in many aspects of mRNA metabolism. The nuclear cap-binding complex (CBC; consisting of CBP20 and CBP80) mediates the stimulatory functions of the cap in pre-mRNA splicing, 3' end formation, and U snRNA export. As little is known about how nuclear CBC mediates the effects of the cap in higher eukaryotes, we have characterized proteins that interact with CBC in HeLa cell nuclear extracts as potential mediators of its function. Using cross-linking and coimmunoprecipitation, we show that eukaryotic translation initiation factor 4G (eIF4G), in addition to its function in the cytoplasm, is a nuclear CBC-interacting protein. We demonstrate that eIF4G interacts with CBC in vitro and that, in addition to its cytoplasmic localization, there is a significant nuclear pool of eIF4G in mammalian cells in vivo. Immunoprecipitation experiments suggest that, in contrast to the cytoplasmic pool, much of the nuclear eIF4G is not associated with eIF4E (translation cap binding protein of eIF4F) but is associated with CBC. While eIF4G stably associates with spliceosomes in vitro and shows close association with spliceosomal snRNPs and splicing factors in vivo, depletion studies show that it does not participate directly in the splicing reaction. Taken together the data indicate that nuclear eIF4G may be recruited to pre-mRNAs via its interaction with CBC and accompanies the mRNA to the cytoplasm, facilitating the switching of CBC for eIF4F. This may provide a mechanism to couple nuclear and cytoplasmic functions of the mRNA cap structure
GDGMV Borehole Database Interface User Guide
This report is the published product of a collaboration between the British Geological Survey (BGS) and the General Department of Geology and Minerals Vietnam (GDGMV) and Ministry of Natural Resources and Environment (MONRE) as part of the Hanoi Urban Geology Project. The project has been ongoing since 2016, funded through the by BGS NC-ODA: Geoscience for Sustainable Futures Programme. The project delivers against three priority themes:
1) Development of Digital Systems and Workflows
2) Urban Geology for Planning Policy and Construction
3) Training, Knowledge Exchange and Stakeholder Engagement
These tasks are delivering new digital data technology, new working practices, and increased institutional capacity with respect to urban geoscience.
The GDGMV Borehole Database Interface outlined in this document is one of many systems developed and put in place. This report should be used in conjunction with the other reports related to this collaboration, including:
OR/21/019 – GDGMV Lexicon Database User Guide
OR/20/55 – Considerations for Borehole Coding and Coded Borehole Data Checking
There is also a toolbox of documents, data tools, and workflows available
Coherent multi-flavour spin dynamics in a fermionic quantum gas
Microscopic spin interaction processes are fundamental for global static and
dynamical magnetic properties of many-body systems. Quantum gases as pure and
well isolated systems offer intriguing possibilities to study basic magnetic
processes including non-equilibrium dynamics. Here, we report on the
realization of a well-controlled fermionic spinor gas in an optical lattice
with tunable effective spin ranging from 1/2 to 9/2. We observe long-lived
intrinsic spin oscillations and investigate the transition from two-body to
many-body dynamics. The latter results in a spin-interaction driven melting of
a band insulator. Via an external magnetic field we control the system's
dimensionality and tune the spin oscillations in and out of resonance. Our
results open new routes to study quantum magnetism of fermionic particles
beyond conventional spin 1/2 systems.Comment: 9 pages, 5 figure
Spin-Nematic Squeezed Vacuum in a Quantum Gas
Using squeezed states it is possible to surpass the standard quantum limit of
measurement uncertainty by reducing the measurement uncertainty of one property
at the expense of another complementary property. Squeezed states were first
demonstrated in optical fields and later with ensembles of pseudo spin-1/2
atoms using non-linear atom-light interactions. Recently, collisional
interactions in ultracold atomic gases have been used to generate a large
degree of quadrature spin squeezing in two-component Bose condensates. For
pseudo spin-1/2 systems, the complementary properties are the different
components of the total spin vector , which fully characterize the state on
an SU(2) Bloch sphere. Here, we measure squeezing in a spin-1 Bose condensate,
an SU(3) system, which requires measurement of the rank-2 nematic or quadrupole
tensor as well to fully characterize the state. Following a quench
through a nematic to ferromagnetic quantum phase transition, squeezing is
observed in the variance of the quadratures up to -8.3(-0.7 +0.6) dB
(-10.3(-0.9 +0.7) dB corrected for detection noise) below the standard quantum
limit. This spin-nematic squeezing is observed for negligible occupation of the
squeezed modes and is analogous to optical two-mode vacuum squeezing. This work
has potential applications to continuous variable quantum information and
quantum-enhanced magnetometry
Evidence for the existence of powder sub-populations in micronized materials : Aerodynamic size-fractions of aerosolized powders possess distinct physicochemical properties
This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.Purpose: To investigate the agglomeration behaviour of the fine ( 12.8 µm) particle fractions of salmeterol xinafoate (SX) and fluticasone propionate (FP) by isolating aerodynamic size fractions and characterising their physicochemical and re-dispersal properties. Methods: Aerodynamic fractionation was conducted using the Next Generation Impactor (NGI). Re-crystallized control particles, unfractionated and fractionated materials were characterized for particle size, morphology, crystallinity and surface energy. Re-dispersal of the particles was assessed using dry dispersion laser diffraction and NGI analysis. Results: Aerosolized SX and FP particles deposited in the NGI as agglomerates of consistent particle/agglomerate morphology. SX particles depositing on Stages 3 and 5 had higher total surface energy than unfractionated SX, with Stage 5 particles showing the greatest surface energy heterogeneity. FP fractions had comparable surface energy distributions and bulk crystallinity but differences in surface chemistry. SX fractions demonstrated higher bulk disorder than unfractionated and re-crystallized particles. Upon aerosolization, the fractions differed in their intrinsic emission and dispersion into a fine particle fraction (< 5.0 µm). Conclusions: Micronized powders consisted of sub-populations of particles displaying distinct physicochemical and powder dispersal properties compared to the unfractionated bulk material. This may have implications for the efficiency of inhaled drug deliveryPeer reviewe
Spectral Energy Distributions of Type 1 AGN in the COSMOS Survey I - The XMM-COSMOS Sample
The "Cosmic Evolution Survey" (COSMOS) enables the study of the Spectral
Energy Distributions (SEDs) of Active Galactic Nuclei (AGN) because of the deep
coverage and rich sampling of frequencies from X-ray to radio. Here we present
a SED catalog of 413 X-ray (\xmm) selected type 1 (emission line FWHM km
s) AGN with Magellan, SDSS or VLT spectrum. The SEDs are corrected for
the Galactic extinction, for broad emission line contributions, constrained
variability, and for host galaxy contribution. We present the mean SED and the
dispersion SEDs after the above corrections in the rest frame 1.4 GHz to 40
keV, and show examples of the variety of SEDs encountered. In the near-infrared
to optical (rest frame -- 4000\AA), the photometry is complete for
the whole sample and the mean SED is derived from detections only. Reddening
and host galaxy contamination could account for a large fraction of the
observed SED variety. The SEDs are all available on-line.Comment: 22 pages, 22 figures, ApJ accepted, scheduled to be published October
20th, 2012, v75
Cosmological Model with a Local Void: New Supernova Constraints
A simple inhomogeneous cosmological model with a local void is constrained
with the latest Union supernova compilation. To fit the supernova data, a large
local void on the scales of 1 Gpc is found, contrary to the small scales of 200
Mpc in the previous finding. A more realistic inhomogeneous cosmological model
may be required to fit the supernova data. Alternatively, a clumpy universe
with clumpiness parameter < 1 can fit the supernova data with reduced local
void scales.Comment: 7 pages, 6 figures, to appears in the proceedings of Particle
Physics, Astrophysics & Quantum Field Theory: 75 Years since Solvay,
Singapore, 27-29 November 200
Evidence for B- -> tau- nu_bar with a Semileptonic Tagging Method
We present a measurement of the decay B- -> tau- nu_bar using a data sample
containing 657 million BB_bar pairs collected at the Upsilon(4S) resonance with
the Belle detector at the KEKB asymmetric-energy e+e- collider. A sample of
BB_bar pairs are tagged by reconstructing one B meson decaying
semileptonically. We detect the B- -> tau- nu_bar candidate in the recoil. We
obtain a signal with a significance of 3.6 standard deviations including
systematic uncertainties, and measure the branching fraction to be Br(B- ->
tau- nu_bar) = [1.54+0.38-0.37(stat)+0.29-0.31(syst)]*10^-4. This result
confirms the evidence for B- -> tau- nu_bar obtained in a previous Belle
measurement that used a hadronic B tagging method.Comment: 7 pages, 3 figures, corrected references, to appear in PRD-R
Influence of apical oxygen on the extent of in-plane exchange interaction in cuprate superconductors
In high Tc superconductors the magnetic and electronic properties are
determined by the probability that valence electrons virtually jump from site
to site in the CuO2 planes, a mechanism opposed by on-site Coulomb repulsion
and favored by hopping integrals. The spatial extent of the latter is related
to transport properties, including superconductivity, and to the dispersion
relation of spin excitations (magnons). Here, for three antiferromagnetic
parent compounds (single-layer Bi2Sr0.99La1.1CuO6+delta, double-layer
Nd1.2Ba1.8Cu3O6 and infinite-layer CaCuO2) differing by the number of apical
atoms, we compare the magnetic spectra measured by resonant inelastic x-ray
scattering over a significant portion of the reciprocal space and with
unprecedented accuracy. We observe that the absence of apical oxygens increases
the in-plane hopping range and, in CaCuO2, it leads to a genuine 3D
exchange-bond network. These results establish a corresponding relation between
the exchange interactions and the crystal structure, and provide fresh insight
into the materials dependence of the superconducting transition temperature.Comment: 9 pages, 4 figures, 1 Table, 42 reference
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