Reduction of gray mold development in table grapes by preharvest sprays with ethanol and calcium chloride.

Preharvest applications of a 16% ethanol (EtOH) solution, containing 1 % of calcium chloride (CaCl2), reduced gray mold development in ‘Chasselas’ table grapes picked at a late harvest date, the losses due to rotten clusters dropped from 15% in controls to 5% in grapes treated with EtOH+CaCl2. Then over a 6-week cold storage, the losses due to gray mold rots were reduced by 50% when storing EtOH+CaCl2 treated clusters, compared to untreated controls. Preliminary experiments had shown that a 2% EtOH solution was already inducing significant drop of gray mold growth. A range of concentrations up to 50% ethanol had been tested in preliminary trials without observing damages to the vines and clusters. The treatments did not induce significant changes to the fruit quality assessed by sensory analyses on healthy berries

Rotational torque measurement device

A device for measuring torque applied through a rotating member. A first torsion reference member is fixedly coupled to the rotating member at a first axial position and a second torsion reference member is fixedly coupled to the rotating member at a second axial position. A first detector detects the passage of the first torsion reference member past the first detector upon each full rotation of the rotating member and to generate a first signal upon each passage of the first torsion reference member. A second detector detects the passage of the second torsion reference member past the second detector upon each full rotation of the rotating member and to generate a second signal upon each passage of the second torsion reference member. A controller calculates a phase difference between the first signal and the second signal relative during rotation of the rotating member under a torsional load.https://digitalcommons.mtu.edu/patents/1003/thumbnail.jp

Experimental phage therapy of burn wound infection : difficult first steps

Antibiotic resistance has become a major public health problem and the antibiotics pipeline is running dry. Bacteriophages (phages) may offer an ‘innovative’ means of infection treatment, which can be combined or alternated with antibiotic therapy and may enhance our abilities to treat bacterial infections successfully. Today, in the Queen Astrid Military Hospital, phage therapy is increasingly considered as part of a salvage therapy for patients in therapeutic dead end, particularly those with multidrug resistant infections. We describe the application of a well-defined and quality controlled phage cocktail, active against Pseudomonas aeruginosa and Staphylococcus aureus, on colonized burn wounds within a modest clinical trial (nine patients, 10 applications), which was approved by a leading Belgian Medical Ethical Committee. No adverse events, clinical abnormalities or changes in laboratory test results that could be related to the application of phages were observed. Unfortunately, this very prudent ‘clinical trial’ did not allow for an adequate evaluation of the efficacy of the phage cocktail. Nevertheless, this first ‘baby step’ revealed several pitfalls and lessons for future experimental phage therapy and helped overcome the psychological hurdles that existed to the use of viruses in the treatment of patients in our burn unit

Brissarthe – Le Bourg

En 1985, le suivi des travaux d’adduction d’eau réalisés dans le bourg de Brissarthe avait permis de délimiter la nécropole mérovingienne. Une nouvelle tranche de travaux allait permettre de compléter les données concernant celle-ci, grossièrement centrée sur l’église (mentionnée en dur dès 866), de 150 m (nord-sud) sur 100 m (est-ouest) ; un autre groupe de sépultures à 120 m de l’église semble appartenir à un ensemble différent. Un des sept coffres examinés a livré une chaînette, deux bague..

Characterization of newly isolated lytic bacteriophages active against Acinetobacter baumannii

Based on genotyping and host range, two newly isolated lytic bacteriophages, myovirus vB_AbaM_Acibel004 and podovirus vB_AbaP_Acibel007, active against Acinetobacter baumannii clinical strains, were selected from a new phage library for further characterization. The complete genomes of the two phages were analyzed. Both phages are characterized by broad host range and essential features of potential therapeutic phages, such as short latent period (27 and 21 min, respectively), high burst size (125 and 145, respectively), stability of activity in liquid culture and low frequency of occurrence of phage-resistant mutant bacterial cells. Genomic analysis showed that while Acibel004 represents a novel bacteriophage with resemblance to some unclassified Pseudomonas aeruginosa phages, Acibel007 belongs to the well-characterized genus of the Phikmvlikevirus. The newly isolated phages can serve as potential candidates for phage cocktails to control A. baumannii infections

Patient Perspectives of the Doctor-at-Home Service

Introduction. Home health care has been established as an effective model for reducing mortality in the elderly. The Doctor-at-Home Service at the Community Health Centers of Burlington (CHCB) has offered home health care to Burlington residents since January 2015. Dr. Karen Sokol, MD, alone provides care to 176 patients at their homes, including at-home palliative care. CHCB hope to expand this program by hiring more providers. Objective. To understand the impact of the Doctor-at-Home Service from the pa- tients’ perspective. Methods. A survey was administered to a cohort of eighteen patients over an 8- week period and addressed topics such as barriers to healthcare, benefits, and costs associated with doctor-at-home programs. A theme analysis on the responses was then conducted to reflect patient opinions. Available summary data describing the pa- tient population was also analyzed. Results. The Doctor- at- Home program serves patients ranging from 26 to 100 years old, with the majority of the patient population comprised of senior citizens. Prior to at home care, patients faced barriers such as lack of transportation, negative past experi- ences, anxiety, and distance from relatives. Four main themes from patient responses were physician-patient relationship, convenience, quality of care, and environment of care. Discussion. Evidence is compelling that there is a desire and need for an exten- sion of the Doctor-at-Home program to reach additional patients. Doctor-at-Home pro- grams could eliminate identified barriers and provide quality care to patients, especially those with specific barriers to access.https://scholarworks.uvm.edu/comphp_gallery/1256/thumbnail.jp

La réforme des retraites de 1993 : quel impact sur l'équivalent patrimonial des droits à retraite ?

Depuis 1993, la France a enregistré plusieurs réformes de son système de retraites, visant avant tout à en assurer la soutenabilité. Cette contribution a pour objectif d’évaluer l’impact de la réforme de 1993 sur l’équivalent patrimonial des droits individuels à la retraite (EPDR), c\u27est-à-dire la somme actuarielle probable des pensions à recevoir, de la date de liquidation des droits jusqu’au décès. Plus précisément, nous mesurons l’impact de cette réforme sur l’EPDR des mono-pensionnés du régime général, à l’aide des données de l’Echantillon Interrégimes de Retraités 2008. Parmi les mesures phares de la réforme de 1993 figure l’augmentation progressive de la durée de cotisation nécessaire pour obtenir une retraite à taux plein au régime général. Cette augmentation est susceptible d’engendrer deux effets opposés : un effet de report de l’âge de liquidation pour conserver un EPDR adéquat pour ses vieux jours (voire l’augmenter) ou un effet de décote, si l’assuré-e ne souhaite, ou ne peut, pas prolonger son activité et subit donc une décote sur sa pension, et partant sur son EPDR. Pour tester les effets nets de la réforme de 1993 sur l’EPDR, nous procédons à des estimations économétriques en différences premières et en doubles différences, ainsi qu’à des estimations par quantiles pour mesurer les impacts le long de la distribution de l’EPDR. Nos estimations montrent des résultats différents selon que les individus partent avant ou après 2004, date d’entrée en vigueur de la réforme. Ainsi, toutes choses égales par ailleurs, un départ en retraite avant 2004 plutôt que postérieurement, augmente l’EPDR des retraités concernés. Toutefois, l’interaction avec les autres variables nuance cette conclusion. D’une part, reporter son départ en retraite réduit l’EPDR moyen d’environ 20% : le report permet d’accumuler des droits supplémentaires, mais sur une période réduite. D’autre part, l’effet de la décote est négatif, mais son intensité est réduite quand les retraités reportent leur départ. En outre, comme les générations 1934-1943 ont subi conjointement les réformes de 1993 et 2003, nos estimations en double différence permettent d’isoler l’effet « pur » de la réforme de 1993 : lorsque les affiliés ont subi une décote, sans avoir reporté leur départ en retraite pour l’atténuer, la liquidation des droits aux conditions de 2003 par rapport aux conditions de 1993 est la plus défavorable. Enfin, les estimations par quantiles montrent que ces effets s’intensifient dans la première moitié de la distribution, et s’atténuent au-delà

Early Detection of Academic Performance During Primary Education Using the Spanish Primary School Aptitude Test (AEI) Battery

The aim of this study was to assess the predictive capacity of some of the most relevant cognitive skills pertaining to the academic field as measured by the Spanish Primary School Aptitude Test Battery. This psychometric tool was applied to all students who were enrolled in the final year of Early Childhood Education (631 students) in the public schools of the province of Alicante (in the South-East of Spain) and a follow-up of their academic progress was carried out when they completed Primary Education (6 school years). The results obtained show that medium-high and high scores in Verbal Aptitude and Numerical Aptitude tests in Early Childhood Education (5 years of age), can predict academic success at the end of Primary Education (12 years of age) in instrumental subjects such as: (1) Language (Verbal Aptitude Odds Ratio = 1.39 and Numerical Aptitude Odds Ratio = 1.39) and (2) Mathematics (Verbal Aptitude Odds Ratio = 1.47 and Numerical Aptitude Odds Ratio = 1.52). We have determined the importance of developing pedagogical programs that stimulate the development of these skills during Early Childhood Education, while implementing support strategies during Primary Education, for those students who present underdeveloped aptitudes in these areas. In this way, school difficulties would be prevented in the instrumental subjects that provide access to other academic areas

Pension Wealth in France: An Assessment on Panel Data

This contribution proposes a measure of pension wealth in the French public PAYG schemes (first and second pillar schemes) and of its distribution among the population of retirees in 2008 using the Echantillon Inter régimes de Retraités (EIR) panel data. We show that aggregate pension wealth amounts to around 4765 billion Euros assuming a 2 percent discount rate. There are significant differences in the amount of individual’s pension wealth between the pension schemes of the private and public sector. Moreover, there is more inequality in the distribution of pension wealth among private sector retirees than public sectorones