Antimatter signals of singlet scalar dark matter

We consider the singlet scalar model of dark matter and study the expected antiproton and positron signals from dark matter annihilations. The regions of the viable parameter space of the model that are excluded by present data are determined, as well as those regions that will be probed by the forthcoming experiment AMS-02. In all cases, different propagation models are investigated, and the possible enhancement due to dark matter substructures is analyzed. We find that the antiproton signal is more easily detectable than the positron one over the whole parameter space. For a typical propagation model and without any boost factor, AMS-02 will be able to probe --via antiprotons-- the singlet model of dark matter up to masses of 600 GeV. Antiprotons constitute, therefore, a promising signal to constraint or detect the singlet scalar model.Comment: 24 pages, 8 figures. v2: minor improvements. Accepted for publication in JCA

Delayed efficacy of radiofrequency catheter ablation on arrhythmias originating in the interventricular basal septum

Delayed efficacy of radiofrequency energy can suppress ventricular arrhythmias after a failed ablation procedure. The implant of cardiac defibrillator for arrhythmia-induced cardiomyopathy should be procrastinated after a period of follow-up. Waiting for delayed efficacy is a reasonable choice to reduce the risk of complications associated with aggressive ablative approaches

Supervised fully polarimetric classification of the Black Forest test site: From MAESTROI to MAC Europe

A study on the performance of a supervised fully polarimetric maximum likelihood classifier for synthetic aperture radar (SAR) data when applied to a specific classification context: forest classification based on age classes and in the presence of a sloping terrain is presented. For the experimental part, the polarimetric AIRSAR data at P, L, and C-band, acquired over the German Black Forest near Freiburg in the frame of the 1989 MAESTRO-1 campaign and the 1991 MAC Europe campaign was used, MAESTRO-1 with an ESA/JRC sponsored campaign, and MAC Europe (Multi-sensor Aircraft Campaign); in both cases the multi-frequency polarimetric JPL Airborne Synthetic Aperture Radar (AIRSAR) radar was flown over a number of European test sites. The study is structured as follows. At first, the general characteristics of the classifier and the dependencies from some parameters, like frequency bands, feature vector, calibration, using test areas lying on a flat terrain are investigated. Once it is determined the optimal conditions for the classifier performance, we then move on to the study of the slope effect. The bulk of this work is performed using the Maestrol data set. Next the classifier performance with the MAC Europe data is considered. The study is divided into two stages: first some of the tests done on the Maestro data are repeated, to highlight the improvements due to the new processing scheme that delivers 16 look data. Second we experiment with multi images classification with two goals: to assess the possibility of using a training set measured from one image to classify areas in different images; and to classify areas on critical slopes using different viewing angles. The main points of the study are listed and some of the results obtained so far are highlighted

Genome-wide analyses of cassava Pathogenesis-related (PR) gene families reveal core transcriptome responses to whitefly infestation, salicylic acid and jasmonic acid.

BACKGROUND:Whiteflies are a threat to cassava (Manihot esculenta), an important staple food in many tropical/subtropical regions. Understanding the molecular mechanisms regulating cassava's responses against this pest is crucial for developing control strategies. Pathogenesis-related (PR) protein families are an integral part of plant immunity. With the availability of whole genome sequences, the annotation and expression programs of the full complement of PR genes in an organism can now be achieved. An understanding of the responses of the entire complement of PR genes during biotic stress and to the defense hormones, salicylic acid (SA) and jasmonic acid (JA), is lacking. Here, we analyze the responses of cassava PR genes to whiteflies, SA, JA, and other biotic aggressors. RESULTS:The cassava genome possesses 14 of the 17 plant PR families, with a total of 447 PR genes. A cassava PR gene nomenclature is proposed. Phylogenetic relatedness of cassava PR proteins to each other and to homologs in poplar, rice and Arabidopsis identified cassava-specific PR gene family expansions. The temporal programs of PR gene expression in response to the whitefly (Aleurotrachelus socialis) in four whitefly-susceptible cassava genotypes showed that 167 of the 447 PR genes were regulated after whitefly infestation. While the timing of PR gene expression varied, over 37% of whitefly-regulated PR genes were downregulated in all four genotypes. Notably, whitefly-responsive PR genes were largely coordinately regulated by SA and JA. The analysis of cassava PR gene expression in response to five other biotic stresses revealed a strong positive correlation between whitefly and Xanthomonas axonopodis and Cassava Brown Streak Virus responses and negative correlations between whitefly and Cassava Mosaic Virus responses. Finally, certain associations between PR genes in cassava expansions and response to biotic stresses were observed among PR families. CONCLUSIONS:This study represents the first genome-wide characterization of PR genes in cassava. PR gene responses to six biotic stresses and to SA and JA are demonstrably different to other angiosperms. We propose that our approach could be applied in other species to fully understand PR gene regulation by pathogens, pests and the canonical defense hormones SA and JA

Cosmic-ray antiproton constraints on light dark matter candidates

Some direct detection experiments have recently collected excess events that could be interpreted as a dark matter (DM) signal, pointing to particles in the $\sim$10 GeV mass range. We show that scenarios in which DM can self-annihilate with significant couplings to quarks are likely excluded by the cosmic-ray (CR) antiproton data, provided the annihilation is S-wave dominated when DM decouples in the early universe. These limits apply to most of supersymmetric candidates, eg in the minimal supersymmetric standard model (MSSM) and in the next-to-MSSM (NMSSM), and more generally to any thermal DM particle with hadronizing annihilation final states.Comment: Contribution to the proceedings of TAUP-2011 (Munich, 5-9 IX 2011). 4 page

Antiholons in one-dimensional t-J models

Using a newly developed hybrid Monte Carlo algorithm for the nearest-neighbor (n.n.) t-J model, we show that antiholons identified in the supersymmetric inverse squared (IS) t-J model are clearly visible in the electron addition spectrum of the n.n. t-J model at J=2t and also for J=0.5t, a value of experimental relevance.Comment: 4 pages, 4 figure

Supersymmetry in models with strong on-site Coulomb repulsion - application to t-J model

A supersymmetric way of imposing the constraint of no double occupancy in models with strong on-site Coulomb repulsion is presented in this paper. In this formulation the physical operators in the constrainted Hilbert space are invariant under local unitary transformations mixing boson and fermion representations. As an illustration the formulation is applied to the $t-J$ model. The model is studied in the mean-field level in the J=0 limit where we show how both the slave-boson and slave-fermion formulations are included naturally in the present approach and how further results beyond both approaches are obtained.Comment: 12 pages, Latex file, 1 figur

Rivaroxaban in atrial fibrillation cardioversion: an update

Currently, atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, with a prevalence of about 2-3% in the general population, representing a powerful risk factor for stroke and systemic thromboembolism and increased mortality and morbidity. Restoration of sinus rhythm is an important treatment option in AF and has a high success rate, but there is the need for an effective anticoagulation strategy to reduce the risk of embolic events. Anticoagulation with vitamin K antagonists is often associated with failure to achieving effective international normalized ratio. In this setting, recent data have led to extended approval for rivaroxaban in clinical practice, because it is effective and safe in patients with AF undergoing cardioversion, avoiding additional health costs and related time loss, while improving patient satisfaction. The present report provides an overview of the main randomized controlled trial and the main real-life studies, documenting the use of rivaroxaban in patients with non-valvular AF who underwent the cardioversion procedure. Considering that novel non-vitamin K antagonist oral anticoagulants in left atrial appendage thrombi resolution is still unknown in the real-world practice, the main findings on the use of rivaroxaban in this setting are also discussed