Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM study on COVID-19.

Objectives To evaluate the strength of association between maternal and pregnancy characteristics and the risk of adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis of a multinational, cohort study on all consecutive pregnant women with laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 2020 from 73 centers from 22 different countries. A confirmed case of COVID-19 was defined as a positive result on real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of nasal and pharyngeal swab specimens. The primary outcome was a composite adverse fetal outcome, defined as the presence of either abortion (pregnancy loss before 22 weeks of gestations), stillbirth (intrauterine fetal death after 22 weeks of gestation), neonatal death (death of a live-born infant within the first 28 days of life), and perinatal death (either stillbirth or neonatal death). Logistic regression analysis was performed to evaluate parameters independently associated with the primary outcome. Logistic regression was reported as odds ratio (OR) with 95% confidence interval (CI). Results Mean gestational age at diagnosis was 30.6+/-9.5 weeks, with 8.0% of women being diagnosed in the first, 22.2% in the second and 69.8% in the third trimester of pregnancy. There were six miscarriage (2.3%), six intrauterine device (IUD) (2.3) and 5 (2.0%) neonatal deaths, with an overall rate of perinatal death of 4.2% (11/265), thus resulting into 17 cases experiencing and 226 not experiencing composite adverse fetal outcome. Neither stillbirths nor neonatal deaths had congenital anomalies found at antenatal or postnatal evaluation. Furthermore, none of the cases experiencing IUD had signs of impending demise at arterial or venous Doppler. Neonatal deaths were all considered as prematurity-related adverse events. Of the 250 live-born neonates, one (0.4%) was found positive at RT-PCR pharyngeal swabs performed after delivery. The mother was tested positive during the third trimester of pregnancy. The newborn was asymptomatic and had negative RT-PCR test after 14 days of life. At logistic regression analysis, gestational age at diagnosis (OR: 0.85, 95% CI 0.8-0.9 per week increase; pPeer reviewe

Analisi dei modelli organizzativi di risposta al COVID-19 in Italia: evidenze da 2 anni di ISTANT REPORT Altems

all’anno 2020 la storia dell’umanità ha dovuto fare i conti con la diffusione del Sars-COV-2 che ha generato in Italia, come in molti Paesi del pianeta una emergenza, sanitaria, sociale ed economica. L’Alta Scuola di Economia e Management dei Sistemi Sani- tari della Facoltà di Economia dell’Università Cattolica del Sacro Cuore, in collaborazione con il Dipartimento di Scienze della Vita e Sanità Pubblica (Sezione di Igiene) della Facoltà di Medicina e Chirurgia “A. Gemelli”, Cerismas (Centro di Ricerca e Studi in Management Sanitario), il Gruppo di Organizzazione Aziendale del DiGES Diparti- mento di Giurisprudenza, Economia e Sociologia dell’Università della Magna Graecia di Catanzaro, e il Centro di Ricerca sulla Leadership in Medicina della Facoltà di Medicina e Chirurgia “A. Gemelli” dell’Università Cattolica del Sacro Cuore, ha settimanalmente pubblicato un Report per analizzare in modo sistematico e comparativo i modelli di risposta adottati dalle Regioni in risposta all’emergenza Covid-19, partendo dall’analisi epidemiologica dell’evoluzione della pandemia. A due anni dal primo paziente in Italia con COVID-19 di Codogno, ALTEMS ha voluto elaborare un report che sintetizzasse tutti gli elementi che hanno composto la risposta alla diffusione del virus soffermandosi sui modelli istituzionali ed organizzativi adottati dalle Regioni italiane. Questa serie settimanale, che aveva già visto una Edizione Speciale dell’Instant Report a fine anno 2020 in prossimità dell’avvio della campagna vaccinale, viene presentata in forma diversa rispetto agli 85 report precedenti. Il presente Report è stato strutturato per fornire una sintesi di quanto accaduto negli ultimi 24 mesi fornendo una lettura complessiva degli eventi e delle modalità di risposta adottate dalle Regioni

Adapted Physical Activity for the Promotion of Health and the Prevention of Multifactorial Chronic Diseases: the Erice Charter

The Erice Charter was unanimously approved at the conclusion of the 47th Residential Course "Adapted Physical Activity in Sport, Wellness and Fitness: New Challenges for Prevention and Health Promotion", held on 20-24 April 2015 in Erice, Italy, at the "Ettore Majorana" Foundation and Centre for Scientific Culture, and promoted by the International School of Epidemiology and Preventive Medicine "G. D'Alessandro" and the Study Group on Movement Sciences for Health of the Italian Society of Hygiene, Preventive Medicine and Public Health. After an intense discussion the participants identified the main points associated with the relevance of physical activity for Public Health, claiming the pivotal role of the Department of Prevention in coordinating and managing preventive actions. The participants underlined the importance of the physicians specialized in Hygiene, Preventive Medicine and Public Health. The contribution of other operators such as physicians specialized in Sport Medicine was stressed. Further, the holders of the new degree in Human Movement and Sport Sciences were considered fundamental contributors for the performance of physical activity and their presence was seen as a promising opportunity for the Departments of Prevention. Primary prevention based on recreational physical activities should become easily accessible for the population, avoiding obstacles such as certification steps or complex bureaucracy. The Sport Doctor is recognized as the principal referent for preliminary physical evaluation and clinical monitoring in secondary and tertiary prevention actions based on adapted physical activities. Developing research in the field is essential as well as implementing higher education on physical activity management in Schools of Public Health

Maternal and Perinatal Outcomes of Pregnant Women with SARS-COV-2 infection

To evaluate maternal and perinatal outcomes of pregnant women affected by SARS-COV-2