Averaging on n-dimensional rectangles

In this work we investigate families of translation invariant differentiation bases B of rectangles in Rn, for which L log^(n−1) L(R^n) is the largest Orlicz space that B differentiates. In particular, we improve on techniques developed by Stokolos in [11] and [13] (see the attached file)

AVERAGING ON n-DIMENSIONAL RECTANGLES

In this work we investigate families of translation invariant differentiation bases B of rectangles in R n , for which L log n−1 L(R n) is the largest Orlicz space that B differentiates. In particular, we improve on techniques developed by A. Stokolos in [7] and [9]

Differentiating Orlicz spaces with rare bases of rectangles

In the current paper, we study how the speed of convergence of a sequence of angles decreasing to zero influences the possibility of constructing a rare differentiation basis of rectangles in the plane, one side of which makes with the horizontal axis an angle belonging to the given sequence, that differentiates precisely a fixed Orlicz space

F22RS SGR No. 2 (Prime Time Class Scheduling)

To Urge and Request that the University Registrar halts the reimplementation of a policy that limits departments to scheduling no more than 55% of their course sections within prime-time hour

On-Line influenza virus quantification for viral production processes thanks to affinity-based surface plasmon resonance biosensor

Influenza virus seasonal epidemics, associated with the constant threat of new pandemic outbreak, challenge vaccine manufacturers to develop responsive processes that can outreach the limitations of traditional egg-based technology. Recent progress made regarding cell culture bioprocesses allowed for numerous alternative strategies to developed future vaccine candidates, as for example the recombinant HA or Virus—like Particles (VLP) vaccines. However, while cell culture allows for more versatility than ovoculture, regarding process development and monitoring, these alternatives still require optimization to seriously concurrence the traditional process. To drive these developments, WHO and regulatory agencies underlined the need for developing better influenza vaccine potency assays1,2. Actual influenza vaccine formulation and lot release rely on single-radial immunodiffusion (SRID) assay, which requires strain-specific reference sera and antigen reagents. However, the annual preparation of these reagents takes between 2 to 6 months and constitutes a critical bottleneck for the release of vaccine lots3. Additionally, SRID is not implementable for process development as such technique cannot handle in-process low concentrated and non-purified material. We developed an assay for rapid and label-free quantification of influenza hemagglutinin (HA) antigen and influenza virus based on surface plasmon resonance (SPR). The method is based on affinity capture of hemagglutinin antigen by sialic-acid terminated glycans present at the surface of the fetuin-functionalized sensor. Conditions were optimized for the regeneration of the surface, in order to run multiple sequential analyses on a unique sensor. Two types of purified standard were used during the development of the assay. Commercial trivalent inactivated vaccine (“TIV”) has been used for the determination of optimal analytical conditions, while a stock of split inactivated H1N1 virus has been produced and calibrated in our laboratory to study the specific response obtained toward this HA subtype. This assay offers a quantification of influenza hemagglutinin within minutes with a wide dynamic range (30 ng/mL-20 µg/mL). Also, the technique provides a limit of detection (LOD) 100 times lower than SRID, and a better reproducibility than SRID and its potential alternatives recently proposed (1,4,5. Additionally, the applicability of this assay for an on-line vaccine production monitoring has been validated by off-line measurement of influenza H1N1 virus particles derived from cell culture supernatant. Such a test allowed to achieve a LOD of 106 Infectious Viral Particles/mL Thus, our assay provides an innovative tool to evaluate influenza new vaccine bioprocesses, from viral production kinetics in mammalian cell culture to vaccine potency evaluation

Reconstitution paléo-environnementale d’un site archéologique insulaire : le prieuré clunisien de Grelonges en bord de Saône (Fareins, département de l’Ain)

L’île de Grelonges, sur la Saône - à Fareins, dans l’Ain - a accueilli un prieuré de moniales clunisiennes au début du XIIe siècle. Aucun vestige visible ne témoignait jusque-là de ce passé monastique. En effet, tout a disparu, y compris l’île qui se trouvait sur la Saône, entre le royaume de Francie occidentale et l’empire germanique. Seul le toponyme et quelques remplois de blocs sculptés médiévaux évoquaient l’histoire du lieu. La découverte fortuite d’un caveau funéraire en 1999 a déclenché une dynamique scientifique autour de ce site. Dans le cadre d’un travail de maîtrise d’archéologie médiévale, soutenue à l’Université Lumière Lyon II en 2002, une étude paléoenvironnementale a été menée. Cette opération fructueuse a eu pour but de retrouver les traces d’anciens chenaux de la Saône qui pouvaient entourer la bande de terre sur laquelle le prieuré avait été édifié, ainsi que de préciser les causes de la disparition précoce de ce site, les moniales l’ayant déserté à l’extrême fin du XIIIe siècle.A clunisan nunnery dating to the beginning of the 12th century was located on the isle of Grelonges in the Saône at Fareins (Ain). The remains of this monastic past and indeed the island itself situated between the kingdom of Western Francia and the Germanic empire has completely disappeared. Only the place name and several reused medieval sculpted blocs evoke the place’s history. The discovery of a funerary vault in 1999 has triggered off new scientific interest around the site. A palaeoenvironmental study of the area was the subject of a Masters degree in Medieval Archaeology at the University of Lyon in 2002, the objectives being to retrace the old channels of the Saône that flowed around the band of land on which the nunnery was erected and to discover the precise causes of the early disappearance of the site, deserted at the end of the 13th century AD.Die – in Fareins, im Departemement Ain – in der Saône gelegene Insel Grelonges hat zu Beginn des 12. Jahrhundertsein Priorat beherbergt, in dem cluniazensische Nonnen von der Welt abgeschieden lebten. Heute zeugen keine sichtbaren Überreste mehr von dieser klösterlichen Vergangenheit. Es ist tatsächlich alles verschwunden, selbst die Insel in der Saône, zwischen dem west- und dem ostfränkischen Reich. Nur das Toponym und ein paar behauene und wiederverwertete mittelalterliche Steinblöcke erinnerten hier an diese Zeit. Die zufällige Entdeckung einer Gruft im Jahr 1999 hat die Wissenschaftler bewogen, sich für den Ort zu interessieren. Im Rahmen einer 2002 an der Universität Lyon II vertretenen „Maîtrise“ im Fach Archäologie des Mittelalters wurde eine Untersuchung der Paläoumwelt durchgeführt. Ziel dieser Studie war es, die alten Rinnen der Saône aufzuspüren, welche den Landstreifen, auf dem das Priorat errichtet worden war, umgeben hatten. Sie sollte auch die Gründe der vorzeitigen Aufgabe des Ortes klären, den die Nonnen in den letzten Jahren des 13. Jahrhunderts verlassen hatten

Basic Measurements of Division 1 Collegiate Baseball Pitchers to Predict Grip Strength and Spin Rate

Basic measurements such as range of motion (ROM), grip strength (GS), height, and arm length have been associated with the rate that the ball spins. Increased spin rate along with the axis of rotation of a baseball is linked to the movement that a pitch experiences during its delivery. This spin rate gives a batter difficulty when trying to contact the ball. Plainly, the more spin the more likely the chance the batter will miss. PURPOSE: The purpose of this study was to use external range of motion (EROM), GS, height, weight, forearm length, and forearm circumference to predict spin rate. METHODS: Thirteen right-handed division 1 collegiate baseball pitchers (height 183.2cm± 6.9cm, weight 90kg ± 12kg, forearm length 27.5cm ± 1.3cm, forearm circumference 29.8cm ± 2.1cm, EROM 111.3° ± 9.0°, GS 57.3kg ± 8.4kg, spin rate 2057.2rpm ±160.5rpm) were recruited for this study. Height and weight measurements were recorded using a Doran physician\u27s scale. Measurements of the right forearm were taken from the medial epicondyle of the humerus to the styloid process of the ulna. Forearm circumference was taken from the thickest portion of the forearm. External rotation was measured using a goniometer from a lying position. Spin rate was calculated using a Yakkertech which uses visual imaging technology to calculate spin rate and eliminates the gyro spin of the ball. Ipsilateral hand grip strength was assessed using a Delsys handgrip dynamometer at 90-degree elbow flexion with the elbow unsupported and hand in a neutral grip. The participant was given three attempts to exert as much force as possible and the maximum force in kg was recorded. External rotation of the glenohumeral joint was measured using a goniometer from a lying position with the humerus abducted 90 degrees the subjects were instructed to start with their forearm in a vertical position then slowly drop the back of their hand toward the table. RESULTS: Data were assessed using a forward stepwise multiple regression to identify a statistically significant (p\u3c 0.05) prediction model of spin rate using basic measurements described above. Forearm length was the only variable that was a statistically significant predictor and accounted for 41.8% of the variance in predicting spin rate. The resulting prediction equation was as follows: Spin rate= -165.655rpm - (80.945x FL; R2.418; SEE=127.8). CONCLUSION: Increased forearm length allows for the moment arm to produce more torque on the ball thus increasing the spin rate allowing increased movement on the ball

Changes in Body Composition Following In-Season Training in Division I Football Athletes

Strength and conditioning programs for football athletes tend to focus on maintaining gains from off-seasoning training. Due to a significant decrease in time spent in the weight room relative to the amount of work on the field, various morphological adaptations may occur. PURPOSE: The purpose of this study was to examine the changes in body composition following in-season training in Division I (DI) athletes. METHODS: Fifteen DI football athletes (mean ± sd; age, 20 ± 2 years; height, 189.6 ± 11.6 cm; weight, 114.1 ± 19.5 kg) completed two separate visits to the Human Performance Laboratory immediately before and after in-season training. Using the Jackson and Pollock (1978) 7-site skinfold prediction equation for 18-61 yr male athletes, each athlete’s body density could be calculated and then percent body fat estimated using the Siri Equation to further classify the athlete. A Lange Skinfold Caliper was used to assess both preseason and postseason measures. Each individual was instructed to relax and not hold tension while measures were being taken on the right side of their body. Paired samples t-test were used to compare pre and post measures of body composition (i.e. % body fat). RESULTS: The results from a dependent t-test revealed a significant difference between preseason and postseason body fat percentage (15.12 ± 4.89% vs 13.98 ± 4.63%; t14 = 3.167; p \u3c 0.01), as well as a significant difference between weight (250.98 ± 43.09lbs vs 242.05 ± 42.32lbs; t14= 3.77; p\u3c 0.01). Post-hoc effect sizes indicate that between differences were large preseason for changes in body fat (d= 1.39) and weight (d= 9.16). CONCLUSION: A large effect size suggests that there are meaningful differences between the values. The strength and conditioning program that the athletes were a part of has effectiveness that kept muscle size and strength throughout the season while losing excess body fat