917 research outputs found

    Stabilization of a supercritical hydrogen / oxygen flame behind a splitter plate

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    The numerical simulation of fluid dynamics and combustion in cryogenic rocket engines is addressed in this paper, with the intent to elucidate flame stabilization mechanisms. A model configuration is devised to allow a fully resolved simulation, both for the dynamics and the flame structure: a two-dimensional splitter plate represents the lip of an injector and the operating point is typical of a real engine. The non-reacting flow field is first scrutinized to evaluate the impact of the large density gradients between the fuel (hydrogen) and oxidizer (oxygen) streams. It is found that the turbulence generated by the splitter is very intense and strongly distorts the high-density-gradient front at both small and large scales. Under reacting conditions, the flame stabilizes right at the lip of the injector, which is a common feature of hydrogen / oxygen flames under these conditions. A particularly complex flame structure is evidenced at the anchoring point, with turbulent transport playing an important role

    Sequencing of bovine herpesvirus 4 v.test strain reveals important genome features

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    Background Bovine herpesvirus 4 (BoHV-4) is a useful model for the human pathogenic gammaherpesviruses Epstein-Barr virus and Kaposi's Sarcoma-associated Herpesvirus. Although genome manipulations of this virus have been greatly facilitated by the cloning of the BoHV-4 V.test strain as a Bacterial Artificial Chromosome (BAC), the lack of a complete genome sequence for this strain limits its experimental use. Methods In this study, we have determined the complete sequence of BoHV-4 V.test strain by a pyrosequencing approach. Results The long unique coding region (LUR) consists of 108,241 bp encoding at least 79 open reading frames and is flanked by several polyrepetitive DNA units (prDNA). As previously suggested, we showed that the prDNA unit located at the left prDNA-LUR junction (prDNA-G) differs from the other prDNA units (prDNA-inner). Namely, the prDNA-G unit lacks the conserved pac-2 cleavage and packaging signal in its right terminal region. Based on the mechanisms of cleavage and packaging of herpesvirus genomes, this feature implies that only genomes bearing left and right end prDNA units are encapsulated into virions. Conclusions In this study, we have determined the complete genome sequence of the BAC-cloned BoHV-4 V.test strain and identified genome organization features that could be important in other herpesviruses

    Effect of pressure on Hydrogen/Oxygen coupled flame-wall interaction

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    The design and optimization of liquid-fuel rocket engines is a major scientific and technological challenge. One particularly critical issue is the heating of solid parts that are subjected to extremely high heat fluxes when exposed to the flame. This in turn changes the injector lip temperature, leading to possibly different flame behaviors and a fully coupled system. As the cham- ber pressure is usually much larger than the critical pressure of the mixture, supercritical flow behaviors add even more complexity to the thermal prob- lem. When simulating such phenomena, these thermodynamic conditions raise both modeling and numerical specific issues. In this paper, both sub- critical and supercritical Hydrogen/Oxygen one-dimensional, laminar flames interacting with solid walls are studied by use of conjugate heat transfer simulations, allowing to evaluate the wall heat flux and temperature, their impact on the flame as well as their sensitivity to high pressure and real gas thermodynamics up to 100 bar where real gas effects are important. At low pressure, results are found in good agreement with previous studies in terms of wall heat flux and quenching distance, and the wall stays close to isothermal. On the contrary, due to important changes of the fluid trans- port properties and the flame characteristics, the wall experiences significant heating at high pressure condition and the flame behavior is modified

    Programming implantable cardioverter-defibrillators in primary prevention: Higher or later

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    SummaryDefibrillator shocks, appropriate or not, are associated with significant morbidity, as they decrease quality of life, can be involved in depression and anxiety, and are known to be proarrhythmic. Most recent data have even shown an association between shocks and overall mortality. As opposed to other defibrillator-related complications, the rate of inappropriate and unnecessary shocks can (and should) be decreased with adequate programming. This review focuses on the different programming strategies and tips available to reduce the rate of shocks in primary prevention patients with left ventricular dysfunction implanted with a defibrillator, as well as some of the manufacturers’ device specificities

    Influence of Environment and Mitochondrial Heritage on the Ecological Characteristics of Fish in a Hybrid Zone

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    Ecological characteristics (growth, morphology, reproduction) arise from the interaction between environmental factors and genetics. Genetic analysis of individuals' life history traits might be used to improve our understanding of mechanisms that form and maintain a hybrid zone.A fish hybrid zone was used to characterize the process of natural selection. Data were collected during two reproductive periods (2001 and 2002) and 1117 individuals (nase, Chondrostama nasus nasus, sofie C. toxostoma toxostoma and hybrids) were sampled. Reproductive dates of the two parental species overlapped at sympatric sites. The nase had an earlier reproductive period than the sofie; males had longer reproductive periods for both species. Hybridisation between female nase and male sofie was the most likely. Hybrids had a reproductive period similar to the inherited parental mitochondrial type. Growth and reproductive information from different environments has been synthesised following a bayesian approach of the von Bertalanffy model. Hybrid life history traits appear to link with maternal heritage. Hybrid size from the age of two and size at first maturity appeared to be closer to the size of the maternal origin species (nase or sofie). Median growth rates for hybrids were similar and intermediate between those of the parental species. We observed variable life history traits for hybrids and pure forms in the different parts of the hybrid zone. Geometrical analysis of the hybrid fish shape gave evidence of two main morphologies with a link to maternal heritage.Selective mating seemed to be the underlying process which, with mitochondrial heritage, could explain the evolution of the studied hybrid zone. More generally, we showed the importance of studies on hybrid zones and specifically the study of individuals' ecological characteristics, to improve our understanding of speciation

    Semantic hyperpriming in schizophrenic patients: increased facilitation or impaired inhibition in semantic association processing?

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    International audiencePrevious studies analyzing semantic priming in schizophrenic patients have reported conflicting results. In the present study, we explored semantic priming in a sample of schizophrenic patients with mild thought disorders. We wondered if distinct cognitive processes, such as facilitation and/or inhibition, underlie semantic hyperpriming and are variously impaired in schizophrenic patients. Using a lexical decision task, we evaluated semantic priming in 15 schizophrenic patients (DSM-IV) with mild thought disorders and 15 healthy controls matched for sex, age, and education level. The task was designed to divide semantic priming into two additive components, namely facilitation effect and inhibition effect. One-sample t-tests were performed to investigate differences in semantic priming, facilitation, and inhibition within each group. ANOVAs were performed to compare the effects of semantic priming, facilitation, and inhibition between groups. Patients displayed greater semantic priming than controls (i.e., hyperpriming), but this was not due to increased facilitation in processing semantically related pairs. On the contrary, hyperpriming was the result of prolonged response time to process semantically unrelated pairs, corresponding to a requirement to inhibit unrelated information. We demonstrated semantic hyperpriming in stabilized schizophrenic patients with mild severity of symptoms. Thus, semantic hyperpriming may be an intrinsic feature of schizophrenia that is not related to the clinical state of patients. Semantic hyperpriming was due to an inhibition effect involved in processing semantically unrelated information not to increased facilitatory effect for related pairs

    Large Eddy Simulation of combustion and heat transfer in a single element GCH4/GOx rocket combustor

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    The single element GCH 4 /GOx rocket combustion chamber developed at the Technische Universität München has been computed using Large Eddy Simulation. The aim of this work is to analyze the flow and combustion features at high pressure, with a particular focus on the prediction of wall heat flux, a key point for the development of reusable engines. The impact of the flow and flame, as well as of the model used, on thermal loads is investigated. Longitudinal distribution of wall heat flux, as well as chamber pressure, have been plotted against experimental data, showing a good agreement. The link between the heat released by the flame, the heat losses and the chamber pressure has been explained by performing an energetic balance of the combustion chamber. A thermally chained numerical simulation of the combustor structure has been used to validate the hypothesis used in the LES

    Simulations Numériques Instationnaires de la combustion turbulente et transcritique dans les moteurs cryotechniques

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    Ces cinquantes dernières années, la majorité des paramètres de conception des moteurs cryotechniques ont été ajustés en l'absence d'une compréhension détaillée des phénomènes de combustion, en raison des limites des diagnostiques expérimentaux et des capacités de calcul. L'objectif de cette thèse est de réaliser des simulations numériques instationnaires d'écoulements réactifs transcritiques de haute fidélité, pour permettre une meilleure compréhension de la dynamique de flamme dans les moteurs cryotechniques et finalement guider leur amélioration. Dans un premier temps, la thermodynamique gaz-réel et son impact sur les schémas numériques sont présentés. Comme la Simulation aux Grandes Echelles (SGE) comporte des équations filtrées, les effets de filtrages induits par la thermodynamique gaz-réel sont ensuite mis en évidence dans une configuration transcritique type et un opérateur de diffusion artificiel, spécifique au gaz réel, est proposé pour lisser les gradients transcritiques en SGE. Dans un deuxième temps, une étude fondamentale du mélange turbulent et de la combustion dans la zone proche-injecteur des moteurs cryotechniques est menée grâce à la Simulation Numérique Directe (SND). Dans le cas non-réactif, les lâchers tourbillonnaires dans le sillage de la lèvre de l injecteur jouent un rôle majeur dans le mélange turbulent et provoquent la formation de structures en peigne déjà observées expérimentalement dans des conditions similaires. Dans le cas réactif, la flamme reste attachée à la lèvre de l'injecteur, sans extinction locale, et les structures en peigne disparaissent. La structure de flamme est analysée et différents modes de combustion sont identifiés. Enfin, une étude de flamme-jet transcritique H2/O2, accrochée à un injecteur coaxial avec et sans retrait interne, est menée. Les résultats numériques sont d'abord validés par des données expérimentales pour l'injecteur sans retrait. Ensuite, la configuration avec retrait est comparée à la solution de référence sans retrait et à des données experimentales pour observer les effets de ce paramètre de conception sur l'efficacité de combustion.In the past fifty years, most design parameters of the combustion chamber of Liquid Rocket Engines (LREs) have been adjusted without a detailed understanding of combustion phenomena, because of both limited experimental diagnostics and numerical capabilities. The objective of the present thesis work is to conduct high-fidelity unsteady numerical simulations of transcritical reacting flows, in order to improve the understanding of flame dynamics in LRE, and eventually provide guidelines for their improvement. First real-gas thermodynamics and its impact on numerical schemes are presented. As Large-Eddy Simulation (LES) involves filtered equations, the filtering effects induced by real-gas thermodynamics are then highlighted in a typical 1D transcritical configuration and a specific real-gas artificial dissipation is proposed to smooth transcritical density gradients in LES. Then, a Direct Numerical Simulation (DNS) study of turbulent mixing and combustion in the near-injector region of LREs is conducted. In the non-reacting case, vortex shedding in the wake of the lip of the injector is shown to play a major role in turbulent mixing, and induces the formation of finger-like structures as observed experimentally in similar operating conditions. In the reacting case, the flame is attached to the injector rim without local extinction and the finger-like structures disappear. The flame structure is analyzed and various combustion modes are identified. Finally, a LES study of a transcritical H2/O2 jet flame, issuing from a coaxial injector with and without inner recess, is conducted. Numerical results are first validated against experimental data for the injector without recess. Then, the recessed configuration is compared to the reference solution and to experimental results, to scrutinize the effects of this design parameter on combustion efficiency.TOULOUSE-INP (315552154) / SudocSudocFranceF

    Exploration of combustion instability triggering using Large Eddy Simulation of a multiple injector Liquid Rocket Engine

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    This article explores the possibility of analyzing combustion instabilities in liq- uid rocket engines by making use of Large Eddy Simulations (LES). Calculations are carried out for a complete small-scale rocket engine, including the injection manifold thrust chamber and nozzle outlet. The engine comprises 42 coaxial injectors feeding the combustion chamber with gaseous hydrogen and liquid oxy- gen and it operates at supercritical pressures with a maximum thermal power of 80 MW. The objective of the study is to predict the occurrence of transverse high-frequency combustion instabilities by comparing two operating points fea- turing different levels of acoustic activity. The LES compares favorably with the experiment for the stable load point and exhibits a nonlinearly unstable trans- verse mode for the experimentally unstable operating condition. A detailed analysis of the instability retrieves the experimental data in terms of spectral features. It is also found that modifications of the flame structures and of the global combustion region configuration have similarities with those observed in recent model scale experiments. It is shown that the overall acoustic activity mainly results from the combination of one transverse and one radial mode of the chamber, which are also strongly coupled with the oxidizer injectors

    Structural and electrical properties of tellurovanadate glasses containing Li2O

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    Glassy materials are promising intercalation compounds, due to their open network structure and absence of grain boundaries. Some glasses containing alkali ions and a high concentration of transition metal ions can present mixed ionic-electronic conductivity and are therefore potential candidates for application as cathode material in Li-ion batteries. The present work is devoted to the ternary system xLi(2)O-(1-x)[0.3V(2)O(5)-0.7TeO(2)] with 0 <= x <= 0.4. These compounds were prepared by heat treatment in air at 800 degrees C followed by traditional quenching. Raman spectroscopy and V-51 nuclear magnetic resonance measurements were performed in order to highlight the structural short range order modifications induced by the introduction of the Li2O network modifier. These structural effects can be related to the electrical behaviour, as studied by complex impedance spectroscopy measurements. (c) 2006 Elsevier B.V. All rights reserved
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