A dynamic simulation of low-carbon policy influences on endogenous electricity demand in an isolated island system

This paper considers the dynamics of electricity demand in response to changes arising from low-carbon policies and socio-economic developments. As part of an investigation into the evolution of such systems on small economically-developed islands, endogenous electricity demand and associated policies are studied for the Azorean island of São Miguel. A comprehensive System Dynamics (SD) model covering the period 2005 − 2050 is presented which captures both historical behaviours and real-world influences on the endogenous demand dynamics of an island-based electricity system. The impact of tourism, energy efficiency and electric vehicles (EV) expansion allied with associated policy options, are critically evaluated by the SD model using a series of scenarios. The model shows that energy efficiency measures exhibit the most significant long-term impact on electricity demand, while in contrast, policies to increase tourism have a much less direct impact and EV expansion has thought-provoking impacts on the long-term demand, although this is not as influential as energy efficiency measures

Deciding Equivalence of Linear Tree-to-Word Transducers in Polynomial Time

We show that the equivalence of deterministic linear top-down tree-to-word transducers is decidable in polynomial time. Linear tree-to-word transducers are non-copying but not necessarily order-preserving and can be used to express XML and other document transformations. The result is based on a partial normal form that provides a basic characterization of the languages produced by linear tree-to-word transducers.Comment: short version of this paper will be published in the proceedings of the 20th Conference on Developments in Language Theory (DLT 2016), Montreal, Canad

Reproductive tract biology: Of mice and men.

The study of male and female reproductive tract development requires expertise in two separate disciplines, developmental biology and endocrinology. For ease of experimentation and economy, the mouse has been used extensively as a model for human development and pathogenesis, and for the most part similarities in developmental processes and hormone action provide ample justification for the relevance of mouse models for human reproductive tract development. Indeed, there are many examples describing the phenotype of human genetic disorders that have a reasonably comparable phenotype in mice, attesting to the congruence between mouse and human development. However, anatomic, developmental and endocrinologic differences exist between mice and humans that (1) must be appreciated and (2) considered with caution when extrapolating information between all animal models and humans. It is critical that the investigator be aware of both the similarities and differences in organogenesis and hormone action within male and female reproductive tracts so as to focus on those features of mouse models with clear relevance to human development/pathology. This review, written by a team with extensive expertise in the anatomy, developmental biology and endocrinology of both mouse and human urogenital tracts, focusses upon the significant human/mouse differences, and when appropriate voices a cautionary note regarding extrapolation of mouse models for understanding development of human male and female reproductive tracts

Dynamical separation of spherical bodies in supersonic flow

An experimental and computational investigation of the unsteady separation behaviour of two spheres in Mach-4 flow is carried out. The spherical bodies, initially contiguous, are released with negligible relative velocity and thereafter fly freely according to the aerodynamic forces experienced. In experiments performed in a supersonic Ludwieg tube, nylon spheres are initially suspended in the test section by weak threads which are detached by the arrival of the flow. The subsequent sphere motions and unsteady flow structures are recorded using high-speed (13 kHz) focused shadowgraphy. The qualitative separation behaviour and the final lateral velocity of the smaller sphere are found to vary strongly with both the radius ratio and the initial alignment angle of the two spheres. More disparate radii and initial configurations in which the smaller sphere centre lies downstream of the larger sphere centre each increases the tendency for the smaller sphere to be entrained within the flow region bounded by the bow shock of the larger body, rather than expelled from this region. At a critical angle for a given radius ratio (or a critical radius ratio for a given angle), transition from entrainment to expulsion occurs; at this critical value, the final lateral velocity is close to maximum due to the same ‘surfing’ effect noted by Laurence & Deiterding (J. Fluid Mech., vol. 676, 2011, pp. 396–431) at hypersonic Mach numbers. A visualization-based tracking algorithm is used to provide quantitative comparisons between the experiments and high-resolution inviscid numerical simulations, with generally favourable agreement

Stability Analysis of an Inline Peptide-based Conjugate for Metal Delivery: Nickel(II)-claMP Tag Epidermal Growth Factor as a Model System

Metals are a key component of many diagnostic imaging and biotechnology applications, and the majority of cancer patients receive a platinum-based drug as part of their treatment. Significant effort has been devoted to developing tight binding synthetic chelators to enable effective targeted delivery of metal-based conjugates, with most successes involving lanthanides rather than transition metals for diagnostic imaging. Chemical conjugation modifies the protein’s properties and generates a heterogeneous mixture of products. Chelator attachment is typically done by converting the amino group on lysines to an amide, which can impact the stability and solubility of the targeting protein and these properties vary among the set of individual conjugate species. Site-specific attachment is sought to reduce complexity and control stability. Here, the metal abstraction peptide (MAP) technology was applied to create the claMP Tag, an inline platform for generating site-specific conjugates involving transition metals. The claMP Tag was genetically encoded into epidermal growth factor (EGF) and loaded with nickel(II) as a model system to demonstrate that the tag within the homogeneous inline conjugate presents sufficient solution stability to enable biotechnology applications. The structure and disulfide network of the protein and chemical stability of the claMP Tag and EGF components were characterized

The Ha Luminosity Function and Star Formation Rate at z\sim 0.2

We have measured the Ha+[N II] fluxes of the I-selected Canada-France Redshift Survey (CFRS) galaxies lying at a redshift z below 0.3, and hence derived the Ha luminosity function. The magnitude limits of the CFRS mean that only the galaxies with M(B) > -21 mag were observed at these redshifts. We obtained a total Ha luminosity density of at least 10^{39.44\pm 0.04} erg/s/Mpc^{3} at a mean z=0.2 for galaxies with rest-fame EW(Ha+[N II]) > 10 Angs. This is twice the value found in the local universe by Gallego et al. 1995. Our Ha star formation rate, derived from Madau (1997) is higher than the UV observations at same z, implying a UV dust extinction of about 1 mag. We found a strong correlation between the Ha luminosity and the absolute magnitude in the B-band: M(B(AB)) = 46.7 - 1.6 log L(Ha). This work will serve as a basis of future studies of Ha luminosity distributions measured from optically-selected spectroscopic surveys of the distant universe, and it will provide a better understanding of the physical processes responsible for the observed galaxy evolution.Comment: Accepted for publication in ApJ, 14 pages, LaTeX (macro aas2pp4.sty), 6 figure

Referencing Sources of Molecular Spectroscopic Data in the Era of Data Science: Application to the HITRAN and AMBDAS Databases

The application described has been designed to create bibliographic entries in large databases with diverse sources automatically, which reduces both the frequency of mistakes and the workload for the administrators. This new system uniquely identifies each reference from its digital object identifier (DOI) and retrieves the corresponding bibliographic information from any of several online services, including the SAO/NASA Astrophysics Data Systems (ADS) and CrossRef APIs. Once parsed into a relational database, the software is able to produce bibliographies in any of several formats, including HTML and BibTeX, for use on websites or printed articles. The application is provided free-of-charge for general use by any scientific database. The power of this application is demonstrated when used to populate reference data for the HITRAN and AMBDAS databases as test cases. HITRAN contains data that is provided by researchers and collaborators throughout the spectroscopic community. These contributors are accredited for their contributions through the bibliography produced alongside the data returned by an online search in HITRAN. Prior to the work presented here, HITRAN and AMBDAS created these bibliographies manually, which is a tedious, time-consuming and error-prone process. The complete code for the new referencing system can be found at \url{https://github.com/hitranonline/refs}.Comment: 11 pages, 5 figures, already published online at https://doi.org/10.3390/atoms802001

Spectrophotometric analysis of ternary uranyl systems to replace tri-N-butyl phosphate (TBP) in used fuel reprocessing

In this report, the interaction of monoamide/diamide and monoamide/diglycolamide mixtures with UO2+2 are investigated in pH = 1 methanolic nitric acid media. These monoamides include N,N-dimethylacetamide (DMAA), N,N-diethylacetamide (DEAA), N,N-dibutylacetamide (DBAA) and N,N-dibutylbutanamide (DBBA). N,N,N′N′-tetraethylmalonamide (TEMA) and N,N,N′,N′-tetraethyldiglycolamide (TEDGA), which were chosen as model diamides and diglycolamides, respectively. Complex stability constants for each ligand were modelled using the Stability Quotients Using Absorbance Data program using UV–visible data. Complex stoichiometry of ligand mixtures was determined using Job plots and UV–Vis spectrometry. Monoamides were confirmed to produce only disolvate complexes with UO2+2 in solution. The log10(K) values for monoamides were found to be independent of amine-side chain length, but were slightly dependent on the carbonyl-side chain length. TEDGA was found to produce multiple uranyl complexes in solution. Job plot data indicated that the uranyl cation strongly prefers to bond either only with the monoamide or diamide in ternary monoamide–diamide–UO2 systems. Monoamide–diglycolamide–UO2 systems were more complicated, with Job plot data indicating the potential for multiple ternary species being present is dependent on the monoamide structure