Exploring critical media health literacy (CMHL) in the online classroom.

Critical media health literacy (CMHL) is concerned with identifying healthrelated messages in the media, acknowledging the potential effects on health behaviours, critically analyzing the content of the message, and the subsequent application of the message to one’s health behaviours (Levin-Zamir & Bertschi, 2018). This exploratory research examined the CMHL skills of students (n = 120) in an entry-level, online asynchronous health and wellness course, by examining their ability to think critically about health-related themes presented in news media articles online and apply course-based knowledge during a Twitter event. Employing a content analysis of tweets from the event, students were found to illustrate CMHL skills when interacting with peers on Twitter, more than when directly assessing online news media. The findings suggest that the course curriculum be altered to include CMHL skills, to better equip students with the ability to identify accurate health information in the media

Female Veterans: Satisfying Patterns of Daily Activities as Defined by the Life Balance Model

This phenomenological case study explored the occupational needs and life satisfaction of one female veteran upon reintegration into civilian life. One female veteran, with 23 years of military service, participated in a semi-structured telephone interview. Results demonstrated that military service negatively impacted the participant’s social interactions, physical and mental wellbeing, and ability to cope with stressors, indicating military service posed difficulties for the participant to engage in meaningful occupations upon reintegration. Recommendations included development of occupation-based interventions using the Person Environment and Occupation framework, and further research to identify appropriate services to facilitate successful reintegration into society for female veterans

The Great Gender Divide: Gender-related discrepancies of N95 mask protection

Background: During the COVID-19 pandemic, healthcare professionals are at increased risk of transmission due to their direct contact with infected patients. To ensure protection, properly fitting personal protective equipment (PPE) must be worn. N95 respirator masks are a component of PPE outlined by the CDC for COVID-19; however, N95 masks do not offer protection if they do not fit properly. Fit testing is performed to ensure adequate seal of the mask and proper fit. Objective: The objective of this project was to attempt to identify a gender-related difference in fittesting failure rates. Methods: A single institutional retrospective review was performed on individuals who underwent fit testing from December 2019 to June 2020. Two mask sizes were available for fit testing (Model 3M1860, Regular/Small). Fit test results were divided into two groups, male or female, and evaluated for failure rates. Reasons for fit test failures were noted as: large-boned, small-boned, facial asymmetry, facial hair, and/or no reason reported. Exclusion criterion included failure due to facial hair. Results: A total of 336 tests were performed during this period, with 31 exclusions for facial hair. Data analyzed included 305 total respirator fit test results: 110 male and 195 female. Females fail at signifcantly higher rates, 6.67%, compared to males, 2.27% (p=0.001). Specifcally, females failed due to being small-boned when compared to reasons for male fit testing failures (p\u3c0.0001). Conclusion: Gender-related differences in PPE fit is not new; however, the COVID- 19 pandemic has made the situation more acute. Females are faced with wearing masks that do not properly fit; N95 masks were not designed for female facial dimensions and because of inadequate fit, female healthcare workers are not properly protected. Developing a gender-specifc approach to designing N95 masks is vital in the upcoming months, as a potential second wave of COVID-19 is approaching.https://jdc.jefferson.edu/sexandgenderhealth/1004/thumbnail.jp

The feasibility of equilibria in large ecosystems: A primary but neglected concept in the complexity-stability debate

The consensus that complexity begets stability in ecosystems was challenged in the seventies, a result recently extended to ecologically-inspired networks. The approaches assume the existence of a feasible equilibrium, i.e. with positive abundances. However, this key assumption has not been tested. We provide analytical results complemented by simulations which show that equilibrium feasibility vanishes in species rich systems. This result leaves us in the uncomfortable situation in which the existence of a feasible equilibrium assumed in local stability criteria is far from granted. We extend our analyses by changing interaction structure and intensity, and find that feasibility and stability is warranted irrespective of species richness with weak interactions. Interestingly, we find that the dynamical behaviour of ecologically inspired architectures is very different and richer than that of unstructured systems. Our results suggest that a general understanding of ecosystem dynamics requires focusing on the interplay between interaction strength and network architecture

The PPE Pandemic: Sex-Related Discrepancies of N95 Mask Fit

During the COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2, healthcare professionals across the world have been at high risk of transmission because of their direct contact with infected patients. In October 2020, the International Council of Nurses (ICN) confirmed that 1,500 nurses had died from COVID-19 in 44 countries and estimated that healthcare worker COVID-19 fatalities worldwide could be more than 20,000. To ensure protection of healthcare personnel, properly fitting personal protective equipment (PPE) must be worn. In a ‘one size fits all’ world, the differences between the fit of PPE for men and women can have devastating consequences. An N95 respirator mask is a component of PPE outlined by the Centers for Disease Control and Prevention (CDC) for protection against COVID-19; however, N95 masks do not offer protection if they do not fit properly. Fit testing is performed to ensure an adequate seal of the mask on the wearer. A single-institution retrospective review was performed on fit testing results for male versus female wearers in an attempt to elucidate a difference in failure rates. Females failed at a significantly higher rate than their male counterparts (6.67% female, 2.72% male; p=0.001), and the reason reported was often due to being ‘small-boned’ (p<0.0001). Sex-related differences in proper PPE fit are not new; however, the COVID-19 pandemic has made the situation more acute, and sex-specific N95 mask designs must be developed quickly, as the pandemic shows little signs of abating

Nationale Standards und Schnittstellen zur Übertragung von Forschungsinformationen

RIS Synergy schafft offene Zugangs- bzw. Austauschmöglichkeiten für Systeme von Fördergebern, Forschungsstätten und der öffentlichen Verwaltung. Ziel ist die Vereinfachung der Zusammenarbeit sowie die Schaffung von einheitlichen und reibungslosen Arbeitsabläufe für alle Beteiligten. Mittel sind die Datenerfassung nach dem Once-Only-Prinzip sowie der auf Standards basierende Austausch von Forschungsinformationen. In den Bereichen Projektabrechnung (Finanzdaten) und Programminformationen konnten während der bisherigen Projektlaufzeit bereits Schnittstellen aufgebaut und erfolgreich in den Echtbetrieb genommen werden. Der vorliegende Artikel beleuchtet diese Ergebnisse und die Herausforderungen im Rahmen der Projektarbeit

Fibronectina biliar no diagnóstico de estenoses biliares

Introdução: Ainda, não existe método ideal para o diagnóstico diferencial entre estenoses biliares malignas e benignas. Este estudo visa a comparar a concentração de fibronectina biliar nos pacientes com e sem estenose biliar maligna. Métodos: Durante a pancreatocolangiografia retrógrada endoscópica (PCRE), foram coletadas amostras de bile de 50 pacientes com estenose biliar extra-hepática maligna (40), benigna (10) e de 10 doentes sem estenose biliar (grupo controle). A fibronectina total na bile foi determinada por ensaio imunoenzimático. A concentração sérica de bilirrubina direta, fosfatase alcalina, gama glutamiltransferase, aspartato aminotransferase e alanina aminotransferase foi determinada nos pacientes com estenose biliar antes da PCRE. O diagnóstico final foi definido por cirurgia, biópsia ou acompanhamento clínico. Resultados: Os pacientes com neoplasia maligna eram significativamente mais idosos (p= 0,02) e apresentaram níveis mais elevados dos testes bioquímicos relacionados à colestase (p< 0,01). Não houve diferença significativa na concentração de fibronectina biliar entre os pacientes com estenose maligna (694,2 ± 823,5 ng/ml), benigna (828,9 ± 925ng/ml) e grupo controle (466,5 ± 621,5 ng/ml), ou entre os pacientes com (721,2 ± 836,6 ng/ml) e sem estenose (466,5 ± 621,5 ng/ml). Conclusões: As médias de idade e de resultados de exames laboratoriais relacionados à colestase foram mais elevadas nos pacientes com neoplasia maligna. A dosagem apenas da fibronectina total na bile não foi eficaz para diagnóstico diferencial das estenoses biliares

The dorsoanterior brain of adult amphioxus shares similarities in expression profile and neuronal composition with the vertebrate telencephalon

Funder: FP7 People: Marie-Curie Actions; doi: http://dx.doi.org/10.13039/100011264; Grant(s): 229597Abstract: Background: The evolutionary origin of the telencephalon, the most anterior part of the vertebrate brain, remains obscure. Since no obvious counterpart to the telencephalon has yet been identified in invertebrate chordates, it is difficult to trace telencephalic origins. One way to identify homologous brain parts between distantly related animal groups is to focus on the combinatorial expression of conserved regionalisation genes that specify brain regions. Results: Here, we report the combined expression of conserved transcription factors known to specify the telencephalon in the vertebrates in the chordate amphioxus. Focusing on adult specimens, we detect specific co-expression of these factors in the dorsal part of the anterior brain vesicle, which we refer to as Pars anterodorsalis (PAD). As in vertebrates, expression of the transcription factors FoxG1, Emx and Lhx2/9 overlaps that of Pax4/6 dorsally and of Nkx2.1 ventrally, where we also detect expression of the Hedgehog ligand. This specific pattern of co-expression is not observed prior to metamorphosis. Similar to the vertebrate telencephalon, the amphioxus PAD is characterised by the presence of GABAergic neurons and dorsal accumulations of glutamatergic as well as dopaminergic neurons. We also observe sustained proliferation of neuronal progenitors at the ventricular zone of the amphioxus brain vesicle, as observed in the vertebrate brain. Conclusions: Our findings suggest that the PAD in the adult amphioxus brain vesicle and the vertebrate telencephalon evolved from the same brain precursor region in ancestral chordates, which would imply homology of these structures. Our comparative data also indicate that this ancestral brain already contained GABA-, glutamatergic and dopaminergic neurons, as is characteristic for the olfactory bulb of the vertebrate telencephalon. We further speculate that the telencephalon might have evolved in vertebrates via a heterochronic shift in developmental timing

Chronic Conditions and Multimorbidity Among Middle-Aged and Elderly Peri-Urban Dwellers in Dar es Salaam, Tanzania

Objectives: Chronic conditions and multimorbidity affect care needs and prevention opportunities. Methods: We studied 2,246 men and women aged ≥40 years within the Dar es Salaam Urban Cohort Study from June 2017 to July 2018. Seventeen chronic conditions were assessed based on self-report, body and blood pressure measurement, blood tests, and screening instruments. Results: Hypertension (51.3%), anemia (34.1%), obesity (32.2%), diabetes (31.6%), depressive symptoms (31.5%), low grip strength (21.2%), and ischemic heart disease (11.9%) were widespread. Multimorbidity was common (73.7%). Women had higher odds of obesity, ischemic heart disease, and high cholesterol (adjusted OR: 2.08–4.16) and lower odds of underweight, low grip strength, alcohol problems, and smoking (adjusted OR: 0.04–0.45). Ten years of age were associated with higher odds of low grip strength, cognitive problems, hypertension, kidney disease, chronic cough, diabetes, high cholesterol, ischemic heart disease, and multimorbidity (adjusted OR: 1.21–1.81) and lower odds of HIV infection (adjusted OR: 0.51). Conclusion: We found a higher prevalence of multimorbidity than previously estimated for middle-aged and elderly people in sub-Saharan Africa. The chronic conditions underlying multimorbidity differed by sex

Depressive symptoms and their association with age, chronic conditions and health status among middle-aged and elderly people in peri-urban Tanzania

Abstract Background Depression is a global mental health challenge. We assessed the prevalence of depressive symptoms and their association with age, chronic conditions, and health status among middle-aged and elderly people in peri-urban Dar es Salaam, Tanzania. Methods Depressive symptoms were measured in 2,220 adults aged over 40 years from two wards of Dar es Salaam using the ten-item version of the Center of Epidemiologic Studies Depression Scale (CES-D-10) and a cut-off score of 10 or higher. The associations of depressive symptoms with age, 13 common chronic conditions, multimorbidity, self-rated health and any limitation in six activities of daily living were examined in univariable and multivariable logistic regressions. Results The estimated prevalence of depressive symptoms was 30.7% (95% CI 28.5–32.9). In univariable regressions, belonging to age groups 45–49 years (OR 1.35 [95% CI 1.04–1.75]) and over 70 years (OR 2.35 [95% CI 1.66–3.33]), chronic conditions, including ischemic heart disease (OR 3.43 [95% CI 2.64–4.46]), tuberculosis (OR 2.42 [95% CI 1.64–3.57]), signs of cognitive problems (OR 1.90 [95% CI 1.35–2.67]), stroke (OR 1.56 [95% CI 1.05–2.32]) and anemia (OR 1.32 [95% CI 1.01–1.71]) and limitations in activities of daily living (OR 1.35 [95% CI 1.07–1.70]) increased the odds of depressive symptoms. Reporting good or very good health was associated with lower odds of depressive symptoms (OR 0.48 [95% CI 0.35–0.66]). Ischemic heart disease and tuberculosis remained independent predictors of depressive symptoms in multivariable regressions. Conclusion Depressive symptoms affected almost one in three people aged over 40 years. Their prevalence differed across age groups and was moderated by chronic conditions, health status and socioeconomic factors