Analytical studies of in-reactor tests of a nuclear light bulb unit cell

Analytical studies of in-reactor tests of nuclear light bulb unit cell using Pewee, nuclear furnace, and high flux isotope reactor

How biased are maximum entropy models?

Maximum entropy models have become popular statistical models in neuroscience and other areas in biology, and can be useful tools for obtaining estimates of mutual information in biological systems. However, maximum entropy models fit to small data sets can be subject to sampling bias; i.e. the true entropy of the data can be severely underestimated. Here we study the sampling properties of estimates of the entropy obtained from maximum entropy models. We show that if the data is generated by a distribution that lies in the model class, the bias is equal to the number of parameters divided by twice the number of observations. However, in practice, the true distribution is usually outside the model class, and we show here that this misspecification can lead to much larger bias. We provide a perturbative approximation of the maximally expected bias when the true model is out of model class, and we illustrate our results using numerical simulations of an Ising model; i.e. the second-order maximum entropy distribution on binary data.

Analytical studies of nuclear light bulb engine radiant heat transfer and performance characteristics

Analytical model of nuclear light bulb engine radiant heat transfer and engine performance, dynamics and control, heat loads and shutdown characteristic

Analytical study of hydrogen turbopump cycles for advanced nuclear rockets Progress report, Sep. 15, 1964 - Sep. 15, 1965

Hydrogen turbopump cycles for obtaining high engine inlet pressures in advanced nuclear rockets, and data on gaseous nuclear reactors and heavy gas containmen

Lunar seismic data analysis

The scientific data transmitted continuously from all ALSEP (Apollo Lunar Surface Experiment Package) stations on the Moon and recorded on instrumentation tapes at receiving stations distributed around the Earth were processed. The processing produced sets of computer-compatible digital tapes, from which various other data sets convenient for analysis were generated. The seismograms were read, various types of seismic events were classified; the detected events were cataloged

An evaluation of the examination process of state chartered credit unions in Virginia

State chartered credit unions in Virginia are by Statute incorporated and regulated by the State Corporation Commission of the Commonwealth. Part of the regulatory process is a periodic examination of the books and records of each credit union to determine compliance with applicable laws and regulations as well as the safety and soundness of depositors\u27 funds. The quality and effectiveness of this examination process has never been measured, nor has it been empirically evaluated to determine its strengths and weaknesses. This study identifies areas of the examination report which can be improved in order to make it a more useful regulatory tool and to provide a more meaningful reference for regulated credit unions

Studies of nuclear light bulb start-up conditions and engine dynamics

Deep Space Network for two-way communications with unmanned spacecraft at planetary distances - Vol.

Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway

Circulating levels of chylomicron remnants (CMRs) increase postprandially and their composition directly reflects dietary lipid intake. These TG-rich lipoproteins likely contribute to the development of endothelial dysfunction, albeit via unknown mechanisms. Here, we investigated how the FA composition of CMRs influences their actions on human aortic endothelial cells (HAECs) by comparing the effects of model CMRs—artificial TG-rich CMR-like particles (A-CRLPs)—containing TGs extracted from fish, DHA-rich algal, corn, or palm oils. HAECs responded with distinct transcriptional programs according to A-CRLP TG content and oxidation status, with genes involved in antioxidant defense and cytoprotection most prominently affected by n-3 PUFA-containing A-CRLPs. These particles were significantly more efficacious inducers of heme oxygenase-1 (HO-1) than n-6 PUFA corn or saturated FA-rich palm CRLPs. Mechanistically, HO-1 induction by all CRLPs requires NADPH oxidase 4, with PUFA-containing particles additionally dependent upon mitochondrial reactive oxygen species. Activation of both p38 MAPK and PPARβ/δ culminates in increased nuclear factor erythroid 2-related factor 2 (Nrf2) expression/nuclear translocation and HO-1 induction. These studies define new molecular pathways coupling endothelial cell activation by model CMRs with adaptive regulation of Nrf2-dependent HO-1 expression and may represent key mechanisms through which dietary FAs differentially impact progression of endothelial dysfunction