181 research outputs found

    Transprofessionalism in modern design education aspect of sociocultural

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    In this article problems of modern design in the conditions of media communications are widely considered. On the basis of the analysis of the studied scientific literature are allocated communicative and sociocultural determination of competences of the transprofessional designer within educational processВ данной статье панорамно рассмотрена проблематика современного дизайна в условиях медийных коммуникаций. На основе анализа исследуемой научной литературы выделены коммуникативная и социокультурная детерминация компетенций дизайнера-транспрофессионала в рамках образовательного процесс

    Interactive tools for stimulation of the socio-communicative potential of patients with aphasia

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    The article presents an original model of personalized logopedic rehabilitation of patients with consequences of acute cerebral circulation disorders, taking into account the peculiarities of their social and communicative potential.В статье представлена оригинальная модель персонифицированной логопедической реабилитации пациентов с последствиями острого нарушения мозгового кровообращения, учитывающая особенности их социально-коммуникативного потенциала

    Differential sensitivity of brainstem vs cortical astrocytes to changes in pH reveals functional regional specialization of astroglia

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    Astrocytes might function as brain interoceptors capable of detecting different (chemo)sensory modalities and transmitting sensory information to the relevant neural networks controlling vital functions. For example, astrocytes which reside near the ventral surface of the brainstem (central respiratory chemosensitive area) respond to physiological decreases in pH with vigorous elevations in intracellular Ca(2+) and release of ATP. ATP transmits astroglial excitation to the brainstem respiratory network and contributes to adaptive changes in lung ventilation. Here we show that in terms of pH-sensitivity ventral brainstem astrocytes are clearly distinct from astrocytes residing in the cerebral cortex. We monitored vesicular fusion in cultured rat brainstem astrocytes using total internal reflection fluorescence microscopy and found that approximately 35% of them respond to acidification with an increased rate of exocytosis of ATP-containing vesicular compartments. These fusion events require intracellular Ca(2+) signaling and are independent of autocrine ATP actions. In contrast, the rate of vesicular fusion in cultured cortical astrocytes is not affected by changes in pH. Compared to cortical astrocytes, ventral brainstem astrocytes display higher levels of expression of genes encoding proteins associated with ATP vesicular transport and fusion, including vesicle-associated membrane protein-3 and vesicular nucleotide transporter. These results suggest that astrocytes residing in different parts of the rat brain are functionally specialized. In contrast to cortical astrocytes, astrocytes of the brainstem chemosensitive area(s) possess signaling properties which are functionally relevant – they are able to sense changes in pH and respond to acidification with enhanced vesicular release of ATP

    Methodical approaches to estimation of level of international competitiveness of regions

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    У роботі розглянуто основні підходи щодо оцінки конкурентоспроможності регіонів та світова практика регіонального бенчмаркетингу; висвітлено особливості міжнародних рейтингів конкурентоспроможності регіонів з урахуванням особливостей їхнього позиціювання на світових ринках як незалежних суб’єктів конкурентної боротьби.The basic approaches to the estimation of competitiveness of regions and world practice of regional benchmarking are highlighted; the features of the international rating of competitiveness of regions are reflected taking into account the features of their positioning on world markets as independent subjects of competitive activity

    Banking Crises: Identification Problems and Resolution

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    This article examines crisis developments in the banking system and contains a classification of banking crises. Banking crises have many common characteristics, but often their course is different. They can vary in nature spread of the crisis in the national economy, the depth and severity, the number of affected financial institutions, among other symptoms. The most dangerous and devastating condition is called systemic banking crisis, a crisis that affected the entire national banking system. The author used method of system analysis, method of comparison and clusterization method. We will analyze resolution strategies and specific anti-crisis tools used in Russia and abroad, and applicable to different conditions. Identification of the crisis is needed to develop and adopt strategies to overcome it. Banking crises can cause different and sometimes completely contradictory factors. Practice shows that there is no universal strategy for normalizing the situation in the banking sector, but in any case it is necessary to note the importance of state participation in the process of overcoming the banking crises. In the absence of government intervention banking crises have serious consequences for the economy. The form of state participation in the process of overcoming a banking crisis and the extent of state involvement in solving the problems of insolvency of banks can be different: the government may restrict the measures to promote and support organization of private capital, to prefer the formal financial support of some banks, to take the banks under state control (control) or eliminate part of banks

    Public-private partnership in the sphere of physical culture and sports

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    According to many expert estimates, the share of state spending on the creation and development of infrastructure projects in the field of physical culture and sports in Russia remains low, and in the current crisis does not cover the existing needs. In this regard, the question of improving the efficiency of the use of budgetary funds and stimulating the flow of private investment in this area remains open. The article analyzes the Russian practice of public-private partnership in the field of physical culture and sports. The forms of public-private partnership in the designated area, development trends and measures of state support existing both at the Federal and regional levels are investigated. Based on the analysis of the ongoing projects, as well as legal mechanisms that ensure the rights of investors in the Russian Federation, conclusions are drawn on the need to improve the mechanisms of support for public-private partnership in the field of physical culture and sports, while it is advisable to determine transparent and unambiguous criteria for the allocation of public funds. The main purpose of the article is to generalize and systematize the mechanisms of state support of private investment in the sports industry. Since the implementation of such projects should take into account the specifics of this area, the current trends in the development of entrepreneurship in the sports sector. It was concluded that the interaction of business in the field of physical culture and sports with the state should achieve a balance between the private interests of business and social objectives that are set and should be addressed in the interests of societ

    IMPLEMENTATION OF RISK MANAGEMENT SYSTEM IN CASE OF DEVELOPMENT OF LEASING CONTRACTS IN THE CONDITIONS OF THE STATE REFORMING OF AN INDUSTRY

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    In article the importance and need of implementation of risk management system in the course of forming of leasing contracts are proved. The most urgent the matter became in connection with the reform of a leasing industry initiated by state bodies of the power. The Bank of Russia and the Ministry of Finance plan implementation of risk management in leasing companies as obligatory element of general structure. Thus, the corresponding scheme with the description of stages of a risk management of the leasing organization is constituted, and its importance for the organizations in the course of the state reform of a leasing industry is also provided

    Цифровые деньги на современном этапе: ключевые риски и направления развития

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    The article explores modern trends in the development of digital money. The purpose of the article is to identify and analyze the risks of digital money, and to study scientific approaches and tools for managing these risks. The authors use general scientific and special research methods, including comparative legal analysis and a systematization method, as well as methods of economic theory: positive analysis and scientific abstraction. The research highlights the strategic challenges and guidelines in the development of digital money in the Russian Federation and shows the difference and common features of digital and electronic money. Based on a comparative analysis of private and national digital money, we conclude that the digital money of Central Banks is more flexible and more reliable for consumers than private cryptocurrencies. We systematize the risks of digital money circulation at the micro, mezzo and macro levels, as well as identify the essential tools for managing them. The authors note that exogenous risk management tools are more typical for private cryptocurrencies, and endogenous tools will apply to digital money of central banks, in particular, the development of an appropriate configuration of Central Bank digital currency. The study may be useful for digital money users, as well as government agencies implementing policies and regulations on the issue and circulation of digital money in Russia.Статья посвящена исследованию современных тенденций в развитии цифровых денег. Цель статьи состоит в идентификации и анализе рисков, присущих цифровым деньгам, и определении научных подходов и инструментов управления обозначенными рисками. Авторы используют общенаучные и специальные методы исследования, включая сравнительно-правовой анализ и метод систематизации, а также методы экономической теории: позитивного анализа и научной абстракции. Выделены стратегические вызовы и ориентиры в развитии цифровых денег в Российской Федерации. Показаны отличие и общие черты цифровых и электронных денег. На основе сравнительного анализа характеристик частных и национальных цифровых денег сделан вывод, что цифровые деньги центробанков обладают большей гибкостью и более надежны для потребителей, чем частные криптовалюты. Систематизированы риски обращения цифровых денег на микро-, мезо- и макроуровнях, а также необходимый инструментарий для управления ими. Авторы отмечают, что для частных криптовалют более характерны экзогенные инструменты управления рисками, а для цифровых денег центральных банков актуальны эндогенные инструменты, в частности разработка соответствующей конфигурации цифровой валюты центробанка. Результаты исследования могут быть полезны для пользователей цифровых денег, а также для государственных органов при реализации политики в области регулирования эмиссии и обращения цифровых денег в России

    IMPLEMENTATION OF RISK MANAGEMENT SYSTEM IN CASE OF DEVELOPMENT OF LEASING CONTRACTS IN THE CONDITIONS OF THE STATE REFORMING OF AN INDUSTRY

    Get PDF
    In article the importance and need of implementation of risk management system in the course of forming of leasing contracts are proved. The most urgent the matter became in connection with the reform of a leasing industry initiated by state bodies of the power. The Bank of Russia and the Ministry of Finance plan implementation of risk management in leasing companies as obligatory element of general structure. Thus, the corresponding scheme with the description of stages of a risk management of the leasing organization is constituted, and its importance for the organizations in the course of the state reform of a leasing industry is also provided
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