Type Ia supernova counts at high z: signatures of cosmological models and progenitors

Determination of the rates at which supernovae of Type Ia (SNe Ia) occur in the early Universe can give signatures of the time spent by the binary progenitor systems to reach explosion and of the geometry of the Universe. Observations made within the Supernova Cosmology Project are already providing the first numbers. Here it is shown that, for any assumed SNe Ia progenitor, SNe Ia counts up to $m_{R}\simeq 23-26$ are useful tests of the SNe Ia progenitor systems and cosmological tracers of a possible non-zero value of the cosmological constant, $\Lambda$. The SNe Ia counts at high redshifts compare differently with those at lower redshifts depending on the cosmological model. Flat $\Omega_{\Lambda}$--dominated universes would show a more significant increase of the SNe Ia counts at $z \sim 1$ than a flat, $\Omega_{M} = 1$ universe. Here we consider three sorts of universes: a flat universe with $H_{0} = 65 km s^{-1} Mpc^{-1}$, $\Omega_{M} = 1.0$, $\Omega_{\Lambda} = 0.0$; an open universe with $H_{0} = 65 km s^{-1} Mpc^{-1}$, $\Omega_{M} = 0.3$, $\Omega_{\Lambda} = 0.0$; and a flat, $\Lambda$--dominated universe with $H_{0} = 65 km s^{-1} Mpc^{-1}$, $\Omega_{M} = 0.3$, $\Omega_{\Lambda} = 0.7$). On the other hand, the SNe Ia counts from one class of binary progenitors (double degenerate systems) should not increase steeply in the $z= 0$ to $z= 1$ range, contrary to what should be seen for other binary progenitors. A measurement of the SNe Ia counts up to $z \sim 1$ is within reach of ongoing SNe Ia searches at high redshifts.Comment: 16 pages, incl. 2 figures. To appear in ApJ (Letters

Type Ia Supernova Scenarios and the Hubble Sequence

The dependence of the Type Ia supernova (SN Ia) rate on galaxy type is examined for three currently proposed scenarios: merging of a Chandrasekhar--mass CO white dwarf (WD) with a CO WD companion, explosion of a sub--Chandrasekhar mass CO WD induced by accretion of material from a He star companion, and explosion of a sub--Chandrasekhar CO WD in a symbiotic system. The variation of the SNe Ia rate and explosion characteristics with time is derived, and its correlation with parent population age and galaxy redshift is discussed. Among current scenarios, CO + He star systems should be absent from E galaxies. Explosion of CO WDs in symbiotic systems could account for the SNe Ia rate in these galaxies. The same might be true for the CO + CO WD scenario, depending on the value of the common envelope parameter. A testable prediction of the sub--Chandrasekhar WD model is that the average brightness and kinetic energy of the SN Ia events should increase with redshift for a given Hubble type. Also for this scenario, going along the Hubble sequence from E to Sc galaxies SNe Ia events should be brighter on average and should show larger mean velocities of the ejecta. The observational correlations strongly suggest that the characteristics of the SNe Ia explosion are linked to parent population age. The scenario in which WDs with masses below the Chandrasekhar mass explode appears the most promising one to explain the observed variation of the SN Ia rate with galaxy type together with the luminosity--expansion velocity trend.Comment: 16 pages uuencoded compressed Postscript, 2 figures included. ApJ Letters, in pres

Quality of government in the Asia Pacific region

The politics and administration of institutional chang

SN~1991T: Reflections of Past Glory

We have obtained photometry and spectra of SN~1991T which extend more than 1000 days past maximum light, by far the longest a SN~Ia has been followed. Although SN~1991T exhibited nearly normal photometric behavior in the first 400 days following maximum, by 600 days its decline had slowed, and by 950~days the supernova brightness was consistent with a constant apparent magnitude of $m_B=21.30$. Spectra near maximum showed minor variations on the SN~Ia theme which grew less conspicuous during the exponential decline. At 270 days the nebular spectrum was composed of Fe and Co lines common to SNe~Ia. However, by 750 days past maximum light, these lines had shifted in wavelength, and were superimposed on a strong blue continuum. The luminosity of SN~1991T at 950 days is more than $9.0\times10^{38}(D/13~{\rm Mpc})^2$~ergs~s$^{-1}$ with a rate of decline of less than $0.04$ mags/100~days. We show that this emission is likely to be light that was emitted by SN~1991T near maximum light which has reflected from foreground dust, much like the light echos observed around SN~1987A.Comment: 15 pages (includes figures and tables) uuencoded compressed postscript, CfA Preprint - To Appear in ApJ

Evolution of social relationships between first-year students at middle school: from cliques to circles

People organize their social relationships under a restriction on the number that a single individual can maintain simultaneously (the so-called Dunbar’s number, ~150). Additionally, personal networks show a characteristic layered structure where each layer corresponds to relationships of different emotional closeness. This structure, referred to as Dunbar’s circles, has mostly been considered from a static viewpoint, and their structure and evolution is largely unexplored. Here we study the issue of the evolution of the structure of positive and negative relationships in early adolescence by using data from students in their first year at middle school obtained from surveys conducted in class in two different waves separated by several months. Our results show that, initially, students have a lower number of total relationships but the majority are more intense and over time they report a higher number of total relationships, but the more intense relationships appear in a lower proportion. We have also found differences in the structure of communities at both temporal moments. While in the first instance the communities that appeared are mixed, made up of both boys and girls, in the second they changed so that they were separated primarily by gender. In addition, the size of each community was stabilized around 15 people, which coincides with the size of the second Dunbar’s circle, known as the sympathy group in social psychology. As a consequence, in groups with around 20 students of the same gender, they tend to split in two separate communities of about 10 each, below the second Dunbar’s circle threshold. On the other hand, groups with more stable community structure appear to go through the inverse process of friendship evolution, becoming more focused on their best relationships. All these results suggest how the layered structure of the personal network, as well as the community structure of the social network, emerge directly from the union of both positive and negative relationships. Thus, we provide a new perspective about its temporal evolution that may have relevant applications to improve school life and student performance. © 2021, The Author(s)

Evaluation in a Cytokine Storm Model in Vivo of the Safety and Efficacy of Intravenous Administration of PRS CK STORM (Standardized Conditioned Medium Obtained by Coculture of Monocytes and Mesenchymal Stromal Cells)

Our research group has been developing a series of biological drugs produced by cocul-ture techniques with M2-polarized macrophages with different primary tissue cells and/or mesen-chymal stromal cells (MSC), generally from fat, to produce anti-inflammatory and anti-fibrotic ef-fects, avoiding the overexpression of pro-inflammatory cytokines by the innate immune system at a given time. One of these products is the drug PRS CK STORM, a medium conditioned by allogenic M2-polarized macrophages, from coculture, with those macrophages M2 with MSC from fat, whose composition, in vitro safety, and efficacy we studied. In the present work, we publish the results obtained in terms of safety (pharmacodynamics and pharmacokinetics) and efficacy of the intravenous application of this biological drug in a murine model of cytokine storm associated with severe infectious processes, including those associated with COVID-19. The results demonstrate the safety and high efficacy of PRS CK STORM as an intravenous drug to prevent and treat the cytokine storm associated with infectious processes, including COVID-19

Cytokine profile and anti-inflammatory activity of a standardized conditioned medium obtained by coculture of monocytes and mesenchymal stromal cells (PRS CK STORM)

Intercellular communication between monocytes/macrophages and cells involved in tissue regeneration, such as mesenchymal stromal cells (MSCs) and primary tissue cells, is essential for tissue regeneration and recovery of homeostasis. Typically, in the final phase of the inflammation-resolving process, this intercellular communication drives an anti-inflammatory immunomodulatory response. To obtain a safe and effective treatment to counteract the cytokine storm associated with a disproportionate immune response to severe infections, including that associated with COVID-19, by means of naturally balanced immunomodulation, our group has standardized the production under GMP-like conditions of a secretome by coculture of macrophages and MSCs. To characterize this proteome, we determined the expression of molecules related to cellular immune response and tissue regeneration, as well as its possible toxicity and anti-inflammatory potency. The results show a specific molecular pattern of interaction between the two cell types studied, with an anti-inflammatory and regenerative profile. In addition, the secretome is not toxic by itself on human PBMC or on THP-1 monocytes and prevents lipopolysaccharide (LPS)-induced growth effects on those cell types. Finally, PRS CK STORM prevents LPS-induced TNF-A and IL-1B secretion from PBMC and from THP-1 cells at the same level as hydrocortisone, demonstrating its anti-inflammatory potency. © 2022 by the authors. Licensee MDPI, Basel, Switzerland

The early spectral evolution of SN 2004dt

Aims. We study the optical spectroscopic properties of Type Ia Supernova (SN Ia) 2004dt, focusing our attention on the early epochs. Methods. Observation triggered soon after the SN 2004dt discovery allowed us to obtain a spectrophotometric coverage from day -10 to almost one year (~353 days) after the B band maximum. Observations carried out on an almost daily basis allowed us a good sampling of the fast spectroscopic evolution of SN 2004dt in the early stages. To obtain this result, low-resolution, long-slit spectroscopy was obtained using a number of facilities. Results. This supernova, which in some absorption lines of its early spectra showed the highest degree of polarization ever measured in any SN Ia, has a complex velocity structure in the outer layers of its ejecta. Unburnt oxygen is present, moving at velocities as high as ~16,700 km/s, with some intermediate-mass elements (Mg, Si, Ca) moving equally fast. Modeling of the spectra based on standard density profiles of the ejecta fails to reproduce the observed features, whereas enhancing the density of outer layers significantly improves the fit. Our analysis indicates the presence of clumps of high-velocity, intermediate-mass elements in the outermost layers, which is also suggested by the spectropolarimetric data.Comment: 13 pages, 15 figures, accepted for pubblication in Astronomy and Astrophysic

Quasinormal modes of gravitational perturbation around a Schwarzschild black hole surrounded by quintessence

In this paper, the quasinormal modes of gravitational perturbation around a Schwarzschild black hole surrounded by quintessence were evaluated by using the third-order WKB approximation. Due to the presence of quintessence, the gravitational wave damps more slowly