Regional and hemispheric impacts of anthropogenic and biomass burning emissions on summertime CO and O3 in the North Atlantic lower free troposphere

Copyright © 2004 American Geophysical Union. All Rights Reserved.We report summertime measurements of CO and O3 obtained during 2001–2003 at the PICO-NARE mountaintop station in the Azores. Frequent events of elevated CO mixing ratios were observed. On the basis of backward trajectories arriving in the free troposphere and global simulations of biomass burning plumes, we attribute nearly all these events to North American pollution outflow and long-range transport of biomass burning emissions. There was a high degree of interannual variability in CO levels: median [CO] ranged from 65 ppbv in 2001 to 104 ppbv in 2003. The highest concentrations were associated with transport of Siberian fire emissions during summer 2003, when Siberian fire activity was unusually high. Ozone mixing ratios also increased (by up to ∼30 ppbv) during the fire events. These findings demonstrate the significant hemispheric scale impact that biomass burning events have on background CO and O3 levels. O3 enhancements of similar magnitude were also observed in North American pollution outflow. O3 and CO were correlated during North American outflow events, with a slope averaging 1.0 (d[O3]/d[CO], ppbv/ppbv) when no fire impact was present. This slope is more than 80% larger than early 1990s observations made in the eastern United States and nearshore outflow region, even after accounting for declining U.S. CO emissions and for CO loss during transport to the Azores, and is not consistent with simple dilution of U.S. outflow with marine background air. We conclude that a significantly larger amount of O3 production occurred in the air sampled during this study, and we suggest several potential reasons for this, each of which could imply potentially significant shortcomings in current estimates of the hemispheric impact of North American emissions on tropospheric ozone and should be evaluated in future studies

First observation of proton reflection from bent crystals

We recently suggested using short bent crystals as primary collimators in a two stage cleaning system for hadron colliders, with the aim of providing larger impact parameters in the secondary bulk absorber, through coherent beam-halo deflection [1]. Tests with crystals a few mm long, performed with 70 GeV proton beams at IEHP in Protvino, showed a channeling efficiency exceeding 85 %. We also observed disturbing phenomena such as dechannelling at large impact angle, insufficient bending induced by volume capture inside the crystal, multiple scattering of non-channeled protons and, for the first time, a proton flux reflected by the crystalline planes. Indeed, protons with a tangent path to the curved planes somewhere inside the crystal itself are deflected in the opposite direction with respect to the channeled particles, with an angle almost twice as large as the critical angle. This effect, up to now only predicted by computer simulations [2], produces a flux of particles in the wrong direction with respect to the absorber, which may hamper the collimation efficiency if neglected

The UA9 experimental layout

The UA9 experimental equipment was installed in the CERN-SPS in March '09 with the aim of investigating crystal assisted collimation in coasting mode. Its basic layout comprises silicon bent crystals acting as primary collimators mounted inside two vacuum vessels. A movable 60 cm long block of tungsten located downstream at about 90 degrees phase advance intercepts the deflected beam. Scintillators, Gas Electron Multiplier chambers and other beam loss monitors measure nuclear loss rates induced by the interaction of the beam halo in the crystal. Roman pots are installed in the path of the deflected particles and are equipped with a Medipix detector to reconstruct the transverse distribution of the impinging beam. Finally UA9 takes advantage of an LHC-collimator prototype installed close to the Roman pot to help in setting the beam conditions and to analyze the efficiency to deflect the beam. This paper describes in details the hardware installed to study the crystal collimation during 2010.Comment: 15pages, 11 figure, submitted to JINS

ANTIBACTERIAL ACTIVITY OF CARBON-CONTAINING COATINGS

The surface biological effect of nanocarbon coatings, which can be used in the clinical practice of implantology due to their unique properties, has been studied

Clinical and Morphological Features of Dysplasia and Early Gastric Cancer in the Patients with Autoimmune Gastritis

Аim: to analyze a series of cases of dysplasia and early gastric cancer developed in patients with autoimmune gastritis (AIG), and to identify their clinical and morphological features.Materials and methods. The study included six cases of detection of early gastric cancer on the background of AIG. Four out of six patients underwent endoscopic treatment, and in three out of six cases patients underwent endoscopic mucosectomy with dissection in the submucosal layer. One patient underwent endoscopic surgery in 2017, he continues annual dynamic follow-up without signs of tumour recurrence. A female patient with type 1 neuroendocrine tumour and mild dysplasia is awaiting treatment.Results. In five out of six patients with AIG, the localization of lesions prevailed in the stomach body, while all detected tumours were early ones, and according to the immunophenotype — of a gastric type. The presented cases of tumours were not accompanied by hyperplasia of neuroendocrine cells directly in the area of the tumour itself, but only in the surrounding gastric mucosa. Additionally, several cases of early gastrointestinal stromal tumours were found, which were characterized by low proliferative activity and had small sizes.Conclusion. The predominance of pseudopyloric metaplasia in the surrounding mucosa allows us to consider pseudopyloric metaplasia as a potentially significant change in the gastric mucosa of patients with AIG that may precede the development of gastric cancer

Deflection of high-energy negative particles in a bent crystal through axial channeling and multiple volume reflection stimulated by doughnut scattering

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Double volume reflection of a proton beam by a sequence of two bent crystals

The doubling of the angle of beam deflection due to volume reflection of protons by a sequence of two bent silicon crystals was experimentally observed at the 400 GeV proton beam of the CERN SPS. A similar sequence of short bent crystals can be used as an efficient primary collimator for the Large Hadron Collider

Observation of focusing of 400 GeV/c proton beam with the help of bent crystals

The results of observation and studies of focusing of 400 GeV/ c proton beam with the help of bent single crystals are presented. Two silicon crystals have been used in the measurements. The focal length of the first and second crystals is found to be 1.48 m and 0.68 m, respectively. The mean square size of the horizontal profile in the focus was 3.1 and 4.3 times as small as at the exit of the crystals

Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review)

Aim. To review the main indications for probiotics prescription in patients with irritable bowel syndrome and to present the materials of an Expert Council, which was held on 18 March 2022 in Moscow.Key points. Gut microbiota disturbance is an integral part of irritable bowel syndrome (IBS) pathogenesis. Changes of colonic microbiota composition are associated with its functional potential modification, which leads to an increasing of the pro-inflammatory immune response, as well as to an exacerbation of the disease symptoms and quality of life decreasing in patients with IBS. The novel coronavirus infection (COVID-19) is an independent risk factor for both exacerbation and onset of IBS, which predispose to increase IBS incidence. Correction of gut microbiota composition with probiotics seems to be a promising therapeutic target for IBS treatment optimizing. The optimal probiotic should be effective, safe, strain-specific, and its dose and duration of administration should be confirmed by the results of clinical studies. Some of the probiotics with proven efficacy in IBS are Alflorex® and Enterol®.Conclusion. Prescription of certain probiotics in IBS is advisable to normalize the frequency and consistency of stools, relieve abdominal pain and bloating, as well as improve patients’ quality of life