Motivational dynamics of German Salafist jihadists: A multi-methodical in-depth study of three paradigmatic cases

Individuals belonging to terrorist organizations accept and often use violence as an instrument of their strategies to achieve their goals. The present study focuses on the motivational dynamics of three contrastively selected paradigmatic cases of extremists that grew up in Germany, joined and supported terrorist organizations abroad, and later disengaged and distanced themselves from the jihadist ideology. An innovative multi-methodical approach was applied to the interviews that combines a biographical reconstruction of the lived experiences with a psychoanalytically informed interpretation of the narratives. First, the biographical trajectories were analyzed on the manifest level: How have the former terrorists experienced their own pathways? What were relevant factors for their engagement in and disengagement from terrorism? Second, to gain a deeper understanding of the unconscious motivational dynamics for involvement in terrorism, key sequences of the narrative interviews were interpreted scenically in a psychoanalytical interpretation group: How did the interviewees express their lived experiences (and why in this particular way)? What latent meanings can be extrapolated that provide deep insights into the motivational backgrounds of their decisions? Based on the results of the triangulation process, characterizing structural hypotheses about case dynamics including protective and risk factors are presented and implications for prevention and intervention approaches are given

Associations Between Experienced and Internalized HIV Stigma, Adversarial Growth, and Health Outcomes in a Nationwide Sample of People Aging with HIV in Germany

HIV-related stigmatization and adversarial growth are known to influence health outcomes in people living with HIV. But not much is known how these psychosocial factors are related to each other and how they interact to influence health outcomes. We tested whether the effect of experienced and internalized stigma on mental health and self-rated health is mediated by adversarial growth, and whether each of these factors is uniquely associated with health outcomes. In our sample of 839 people aging with HIV in Germany based on a cross-sectional study design we did not find an indirect effect of experienced HIV stigma on health outcomes and a very small indirect effect of internalized HIV stigma. All variables were significant predictors of health outcomes in multiple regression analyses

Adjuvant Chemotherapy for Brain Tumors Delivered via a Novel Intra-Cavity Moldable Polymer Matrix

Introduction Polymer-based delivery systems offer innovative intra-cavity administration of drugs, with the potential to better target micro-deposits of cancer cells in brain parenchyma beyond the resected cavity. Here we evaluate clinical utility, toxicity and sustained drug release capability of a novel formulation of poly(lactic-co-glycolic acid) (PLGA)/poly(ethylene glycol) (PEG) microparticles. Methods PLGA/PEG microparticle-based matrices were molded around an ex vivo brain pseudo-resection cavity and analyzed using magnetic resonance imaging and computerized tomography. In vitro toxicity of the polymer was assessed using tumor and endothelial cells and drug release from trichostatin A-, etoposide- and methotrexate-loaded matrices was determined. To verify activity of released agents, tumor cells were seeded onto drug-loaded matrices and viability assessed. Results PLGA/PEG matrices can be molded around a pseudo-resection cavity wall with no polymer-related artifact on clinical scans. The polymer withstands fractionated radiotherapy, with no disruption of microparticle structure. No toxicity was evident when tumor or endothelial cells were grown on control matrices in vitro. Trichostatin A, etoposide and methotrexate were released from the matrices over a 3-4 week period in vitro and etoposide released over 3 days in vivo, with released agents retaining cytotoxic capabilities. PLGA/PEG microparticle-based matrices molded around a resection cavity wall are distinguishable in clinical scanning modalities. Matrices are non-toxic in vitro suggesting good biocompatibility in vivo. Active trichostatin A, etoposide and methotrexate can be incorporated and released gradually from matrices, with radiotherapy unlikely to interfere with release. Conclusion The PLGA/PEG delivery system offers an innovative intra-cavity approach to administer chemotherapeutics for improved local control of malignant brain tumors

Educational Transitions in War and Refugee Contexts: Youth Biographies in Afghanistan and Austria

This article addresses educational transitions under conditions of multiple insecurities. By analyzing empirical data of two research projects with youths in Afghanistan and refugee students in Austria, we show how young peoplemake sense of the social and educational inequalities they encounter on their educational pathways within different national, socio‐political, and institutional contexts. We present in‐depth analyses of two cases to elaborate how young people in different parts of the world conceive of their futures when basic security needs are not met, and how they make sense of the social and educational inequalities they face during their transition processes. After living through repeatedly fractured perspectives, young people have to make sense of their biographical experiences and continuously (re)design their plans while facing uncertain futures. In the Afghan Youth Project, we reconstructed a collective - and morally charged - biographical orientation of future plans. This orientation can also be understood as a critical response to persistent fragility and inequality and suggests an imagined generational hold and sense of belonging. In the Austrian project Translating Wor(l)ds, we reconstructed continuing experiences of educational exclusion, marginalization, and devaluation in different migration societies throughout refugee routes. Educational transitions, which can be challenging for all young people, take on special relevance under these conditions. Combining biographical and socio‐psychological research perspectives allows us to reconstruct educational processes as cumulative, non‐linear processes and to reveal the ambiguities, contradictions, and ruptures woven into them, as well as the subjects' constructions of sense and agency

Dealing with Dilemmas of Difference - Ethical and Psychological Considerations of “Othering” and “Peer Dialogues” in the Research Encounter

In this paper we review two qualitative interview studies, in which dilemmas of difference played a decisive role. With regard to the first study, which focused on the influence of migration backgrounds in student’s perception of Holocaust Education in Germany, we discuss several research decisions that were made to avoid methodological othering. Concerning a study on HIV risk behavior of gay and bisexual men, psychological challenges of a participa-tory approach that involved peer interviewers are outlined. We argue that strategies of recognition of the “other” - seen as a reflexive agent - have to be developed systematically as an ethical precondition of socially responsible research.Stigma, othering, participatory research, research ethics, psychology, reflexivity

Introduction to the Special Issue: European Contributions to Strong Reflexivity

This special issue is devoted to reflexivity as an epistemic tool in qualitative research. We suggest a distinction between epistemically weak and epistemically strong reflexivity and present examples for strongly reflexive research from the German-speaking countries and the United Kingdom. The issue pursues three major goals: First, it provides a vocabulary to deepen the discussion about the epistemic dimensions of reflexivity. Second, it intervenes in hegemonic discourses on the “threat of subjectivity” and shows that approaches often perceived as “more subjective” and therefore less valid use, in fact, an epistemically stronger concept of reflexivity. Third, it offers insight into some innovative areas of strongly reflexive research in Europe. A comparison of these methodologies shows that the use of reflexivity as an epistemic tool is compatible with a wide range of approaches.publishe

Sociodemographic, HIV-Related Characteristics, and Health Care Factors as Predictors of Self-Reported Vaccination Coverage in a Nationwide Sample of People Aging with HIV in Germany

Preventing infectious diseases through vaccination becomes more significant among the growing population of people aging with HIV. Coverage rates for vaccinations and factors associated with vaccination utilization among this population in Germany are unknown. We assessed the coverage of eight recommended vaccinations in a certain time frame in our convenience sample of 903 people living with HIV aged 50 years and older. We analysed coverage rates and used bivariate and multiple linear regression analyses to identify factors associated with number of reported vaccinations. Coverage rates in our sample ranged between 51.0% for meningococcus disease and 84.6% for the triple vaccination against tetanus, diphtheria, and pertussis. All rates were higher compared to the German general population. Seven factors were related to the number of vaccinations in multiple regression analysis: sexual orientation, education, relationship status, CD4 count, time since last visit to HIV specialist, type of HIV specialist, and distance to HIV specialist. Vaccination coverage among people aging with HIV in Germany is high, but not optimal. To improve vaccination uptake, strengthened efforts need to be focused on female and heterosexual male patients, socioeconomically disadvantaged patients, and patients with barriers to access regular HIV care

Comorbidities and psychosocial factors as correlates of self-reported falls in a nationwide sample of community-dwelling people aging with HIV in Germany

Background Falls are a frequent health problem with potentially severe consequences among the elderly. Due to the aging HIV population, there is a growing interest in falls as a geriatric syndrome in HIV research and clinical practice. Previous studies found rather high prevalences of falls in this population and focused on biomedical and demographic risk factors for falls. Psychosocial risk factors like stigma, social support or loneliness were not previously assessed as correlates of fall events in this population. Methods We assessed self-reported fall frequency in the past 12 months in a nationwide sample of 897 community-dwelling people aged 50 years or older living with HIV in Germany using a cross-sectional study design. We calculated odds of any fall for sociodemographic and HIV-related variables in bivariate analyses and for comorbidities, and psychosocial variables in bivariate and adjusted analyses. Results Eighteen percent of our participants reported at least one fall in the preceding 12 months, 12 % reported recurring falls. A lower socioeconomic status, being single and living alone were significantly associated with a higher risk for falling. An AIDS diagnosis was related to fall risk, but time since diagnosis and a detectable viral load were not. Reporting at least one comorbidity increased fall risk in our sample 2.5 times (95% CI: 1.59; 3.97). The strongest association with fall risk was found for diseases of the central nervous system, heart disease, rheumatism, osteoporosis, and chronic pain. Experienced HIV stigma (AOR: 2.11; 95% CI: 1.58; 2.83) and internalized HIV stigma (AOR: 1.43; 95% CI: 1.12; 1.85), as well as social support (AOR: .92; 95% CI: .86; .99) and loneliness (AOR: 1.51; 95% CI: 1.22; 1.87) were significantly related to fall risk in bivariate and adjusted analyses. Conclusions We found a low prevalence of falls in our sample of community-dwelling people aging with HIV. Our results show evidence for a strong association between comorbidity and falling, and between psychosocial factors and falling. Especially the strong association between experienced HIV stigma and fall risk is noteworthy and adds falls to the list of health outcomes affected by HIV stigma