1,504 research outputs found
Onderzoek Sclerotinia in 2012 : Sclerotiën, sporen, BOS en spuittechniek
De problemen met Sclerotinia (rattenkeutelziekte), veroorzaakt door de schimmel Sclerotinia sclerotiorum, nemen de laatste jaren steeds meer toe. In diverse vollegrondsgroenten is Sclerotinia een van de belangrijkste ziekten. Om te komen tot een integrale aanpak van de problematiek is er door de Productschappen Tuinbouw en Akkerbouw voor 2012 gekozen voor een gezamenlijke financiering van een aantal onderzoeksthema's die ondergebracht zijn bij de onderzoeksinstellingen DLV Plant, PPO-AGV en Proeftuin Zwaagdijk. Deze thema’s waren: speuren naar sporen; aantal sclerotiën; beslissingsondersteunende systemen (BOS); spuittechniek
Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group
Sulfonylureas, a commonly used class of medication used to treat type 2 diabetes, have been associated with an increased risk of cardiovascular disease. Their effects on QT interval duration and related electrocardiographic phenotypes are potential mechanisms for this adverse effect. In 11 ethnically diverse cohorts that included 71 857 European, African-American and Hispanic/Latino ancestry individuals with repeated measures of medication use and electrocardiogram (ECG) measurements, we conducted a pharmacogenomic genome-wide association study of sulfonylurea use and three ECG phenotypes: QT, JT and QRS intervals. In ancestry-specific meta-analyses, eight novel pharmacogenomic loci met the threshold for genome-wide significance (P<5 × 10−8), and a pharmacokinetic variant in CYP2C9 (rs1057910) that has been associated with sulfonylurea-related treatment effects and other adverse drug reactions in previous studies was replicated. Additional research is needed to replicate the novel findings and to understand their biological basis
Factors facilitating and hindering the implementation of the European Society of Cardiology Syncope Guidelines at the Emergency Department: a nationwide qualitative study
Aims: Syncope care is often fragmented and inefficient. Structuring syncope care through implementation of guidelines and Syncope Units has been shown to improve diagnostic yield, reduce costs and improve quality of life. We implemented the European Society of Cardiology (ESC) 2018 syncope guidelines at the Emergency Departments (ED) and established Syncope Units in five Dutch hospitals. We evaluated the implementation process by identifying factors that hinder ('barriers') and facilitate ('facilitators') the implementation.Methods and results: We conducted, recorded and transcribed semi-structured interviews with 19 specialists and residents involved in syncope care from neurology, cardiology, internal medicine and emergency medicine. Two researchers independently classified the reported barriers and facilitators, according to the framework of qualitative research (Flottorp), which distinguished several separate fields ('levels'). Software package Atlas.ti was used for analysis.We identified 31 barriers and 22 facilitators. Most barriers occurred on the level of the individual health care professional (e.g. inexperienced residents having to work with the guideline at the ED) and the organizational context (e.g. specialists not relinquishing preceding procedures). Participants reported most facilitators at the level of innovation (e.g. structured work -flow at the ED). The multidisciplinary Syncope Unit was welcomed as useful solution to a perceived need in clinical practice.Conclusion: Implementing ESC syncope guidelines at the ED and establishing Syncope Units facilitated a structured multidisciplinary work-up for syncope patients. Most identified barriers related to the individual health care professional and the organizational context. Future implementation of the multidisciplinary guideline should be tailored to address these barriers.(c) 2021 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http:// creativecommons.org/licenses/by/4.0/).Analysis and support of clinical decision makin
A Measurement of the Decay Asymmetry Parameters in \Xi_{c}^{0}\to \X^{-}\pi^{+}
Using the CLEO II detector at the Cornell Electron Storage Ring we have
measured the decay asymmetry parameter in the decay . We find , using the world average value of
we obtain . The physically allowed range of a decay
asymmetry parameter is . Our result prefers a negative value:
is at the 90% CL. The central value occupies the
middle of the theoretically expected range but is not yet precise enough to
choose between models.Comment: 10 pages postscript, also available through
http://w4.lns.cornell.edu/public/CLN
Azimuthal anisotropy and correlations in p+p, d+Au and Au+Au collisions at 200 GeV
We present the first measurement of directed flow () at RHIC. is
found to be consistent with zero at pseudorapidities from -1.2 to 1.2,
then rises to the level of a couple of percent over the range . The latter observation is similar to data from NA49 if the SPS rapidities
are shifted by the difference in beam rapidity between RHIC and SPS.
Back-to-back jets emitted out-of-plane are found to be suppressed more if
compared to those emitted in-plane, which is consistent with {\it jet
quenching}. Using the scalar product method, we systematically compared
azimuthal correlations from p+p, d+Au and Au+Au collisions. Flow and non-flow
from these three different collision systems are discussed.Comment: Quark Matter 2004 proceeding, 4 pages, 3 figure
Azimuthal anisotropy: the higher harmonics
We report the first observations of the fourth harmonic (v_4) in the
azimuthal distribution of particles at RHIC. The measurement was done taking
advantage of the large elliptic flow generated at RHIC. The integrated v_4 is
about a factor of 10 smaller than v_2. For the sixth (v_6) and eighth (v_8)
harmonics upper limits on the magnitudes are reported.Comment: 4 pages, 6 figures, contribution to the Quark Matter 2004 proceeding
Strange Resonance Production in p+p and Au+Au Collisions at RHIC Energies
Resonance yields and spectra from elementary p+p and Au+Au collisions at
200 GeV from the STAR experiment at RHIC are presented
and discussed in terms of chemical and thermal freeze-out conditions. Thermal
models do not adequately describe the yields of the resonance production in
central Au+Au collisions. The approach to include elastic hadronic interactions
between chemical freeze-out and thermal freeze-out suggests a time of 5 fm/c.Comment: 4 pages, 7 figures, proceedings of the Quark Matter 2004, in Oakland,
California, to be published in Journal of Physics G: Nuclear and Particle
Physic
Identified particles at large transverse momenta in STAR in Au+Au collisions @ sqrt(s_NN) = 200 GeV
We report measurements of the ratios of identified hadrons (pi,K,p,Lambda) in
Au+Au collisions at sqrt(s_NN) = 200 GeV as a function of both collision
centrality and transverse momentum (p_T). Ratios of anti-baryon to baryon
yields are independent of p_T within 2<p_T <6 GeV/c indicating that, for such a
range, our measurements are inconsistent with theoretical pQCD calculations
predicting a decrease due to a stronger contribution from valence quark
scattering. For both strange and non-strange species, a strong baryon
enhancement relative to meson yields is observed as a function of collision
centrality in this intermediate p_T region, leading to p/pi and Lambda/K ratios
greater than unity. The nuclear modification factor, R_cp (central relative to
peripheral collisions), is used to illustrate the interplay between jet
quenching and hadron production. The physics implications of these measurements
are discussed with reference to different theoretical models.Comment: 5 pages, 4 figures. Proceedings of Quark Matter 2004 Conference, Jan
2004, Oakland, USA. Submitted to Journal of Physics
High- electron distributions in d+Au and p+p collisions at RHIC
We present preliminary measurements of electron and positron spectra in d+Au
and p+p collisions at GeV for GeV/c.
These measurements were carried out using the STAR Time Projection Chamber
(TPC) and the Barrel Electromagnetic calorimeter (EMC). Overall hadron
rejection factors in the range of have been achieved. In this work we
describe the measurement technique used to discriminate electrons from hadrons
and compare the results for single electron spectra with Pythia based pQCD
calculations for electrons from heavy-quark semi-leptonic decays.Comment: Quark Matter 2004 conference proceeding
Plasma Wakefield Acceleration with a Modulated Proton Bunch
The plasma wakefield amplitudes which could be achieved via the modulation of
a long proton bunch are investigated. We find that in the limit of long bunches
compared to the plasma wavelength, the strength of the accelerating fields is
directly proportional to the number of particles in the drive bunch and
inversely proportional to the square of the transverse bunch size. The scaling
laws were tested and verified in detailed simulations using parameters of
existing proton accelerators, and large electric fields were achieved, reaching
1 GV/m for LHC bunches. Energy gains for test electrons beyond 6 TeV were found
in this case.Comment: 9 pages, 7 figure
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