Mosquito-repellent activities of a north central Nigeria local Hyptis suaveolens Essential oil and its toxicity evaluation in mice

Aim: Mosquito-repellent activities of Hyptis suaveolens essential oil (EO) obtained from Kwara State, north central Nigeria; and its toxicity in mice were evaluated. Materials and Methods: Hyptis suaveolens plants were collected from University of Ilorin premises. Fresh leaves were weighed, pound, hydrodistilled and the EO characterised using GCMS. Mosquitoes (female anopheles and culex) 150 were bred from larva stage in the laboratory against which the repellency activities were determined. Fifteen (15) adult mice with the average weight of (25 ±2.21 g) were randomly assigned into three (3) groups (A-C), of five (5) mice each. Daily administration of distilled water, EO 100 mg/kg body weight and 500 mg/kg body weight were done oropharyngeally for seven days to groups A, B and C respectively. The mice were sacrificed, and the blood, liver and kidney of the animals were collected. Blood, tissues, and serum parameters were assayed for in the mice. Results: Caryophyllene oxide, caryophyllene, spathulenol, alloaromadendrene, benzaldehyde and bornanone were some of the compounds confirmed present in the EO. The EO in water (1:99) is 100% efficacious, for up to 60 minutes. The EO induced significant increase (p<0.05) the blood levels of WBC, RBC, HCT, HGB in all treated groups. Serum albumin, total and direct bilirubin, and the total protein in all the treated groups were significantly reduced while no significant difference in the activities of ALP, ALT and AST in the liver, kidney and serum of treated groups occurred when compared with the control. The levels of the serum urea and creatinine, increased significantly in all the treated groups (p<0.05). Conclusion: The Hyptis suaveolens essential oil possesses mosquito-repellent activities but may cause adverse on the enzymatic and haematological, liver and kidney functions at 500 mg/kg body weight in mice

Comparative sensitivity of maize weevil to essential oil of Hoslundia opposita Vahl leaves subjected to different drying regimes

Received: 2016-06-11 | Accepted: 2016-07-28 | Available online: 2017-09-30http://dx.doi.org/10.15414/afz.2017.20.03.54-59Botanical essential oils (EOs) are effective alternatives to over-dependence on synthetic insecticides in stored product protection. However, the burden of handling bulky fresh botanicals needed for EO extraction and the tendency of the freshly harvested botanical to rot in transit, if wrongly handled, can be bottlenecks to pilot scale application of EO. Therefore, this study evaluates the comparative efficacy of the EOs obtained from freshly harvested Hoslundia opposita Vahl (Lamiaceae) and plants exposed to different shade-drying regimes (1-5 days) against maize weevil, Sitophilus zeamais Motschulsky, under laboratory conditions. Evaluation included fumigant toxicity and repellence bioassays. At 2 hours after exposure (HAE), EO of freshly harvested H. opposita leaves caused significantly (P < 0.001) lower mortality (53.30 %) than the value observed in H. opposita leaves dried for 5 days (90.00 %). The lethal time for 90.00 % of the weevils (LT90) obtained in EO from H. opposita leaves dried for 5 days (2.00 h) was significantly lower than 2.80 and 7.14 h obtained in EOs from the fresh and 1 day-dried leaves, respectively. At 1 HAE, EOs obtained from H. opposita leaves dried for 4 and 5 days caused 60.00 % repellence which was significantly higher than 20.00 % observed in fresh leaves. At 2 HAE, EOs obtained from H. opposita dried for 4 and 5 days caused significantly higher repellence (100.00 and 80.00 %, respectively) than what was observed in fresh leaves (70.00 %). The results imply that shade drying freshly harvested H. opposita leaves has no deleterious effects on the efficacy of its EO against maize weevil.Keywords: bird gooseberry, botanical essential oils, drying regimes, Hoslundia opposita Vahl., insecticidal, maize weevil, Sitophilus zeamais MotschulskyReferences AGAH, M. and NAJAFIAN, S. (2012) Essential oil content and composition of Lippa citriodora as affected by drying method before flowering stages. In European Journal of Experimental Biology, vol. 2, no 5, pp 1771-1777.ARABHOSSEINI, A. et al. (2006) Loss of essential oil of tarragon (Artemisia dracunculus L.) due to drying. In Journal of the  Scence of Food and Agriculture, vol. 86, pp 2543-2550. doi:http://dx.http://dx.doi.org/10.1002/jsfa.2641BABARINDE G. O., BABARINDE S. A. and OGUNSOLA S. O. (2013a) Effect of maize weevil (Sitophilus zeamais Motschulsky 1855) infestation on the quality of three commercial pastas. 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Towards the conversion of carbohydrate biomass feedstocks to biofuels via hydroxylmethylfurfural

This review appraises the chemical conversion processes recently reported for the production of hydroxylmethylfurfural (HMF), a key biorefining intermediate, from carbohydrate biomass feedstocks. Catalytic sites or groups required for the efficient and selective conversion of hexose substrates to HMF are examined. The principle of concerted catalysis was used to rationalise the dehydration of fructose and glucose to HMF in non-aqueous media. A survey of reported reaction routes to diesel-range biofuel intermediates from HMF or furfural is presented and self-condensation reaction routes for linking two or more HMF and furfural units together toward obtaining kerosene and diesel-range biofuel intermediates are highlighted. The reaction routes include: benzoin condensation, condensation of furfuryl alcohols, hetero Diels–Alder reaction and ketonisation reaction. These reaction routes are yet to be exploited despite their potential for obtaining kerosene and diesel-range biofuel intermediates exclusively from furfural or hydroxylmethylfurfural