Quantum-limited mass flow of liquid 3^{3}He

We consider theoretically the possibility of observing unusual quantum fluid behavior in liquid $^{3}$He and solutions of $^{3}$He in $^{4}$He systems confined to nano-channels. In the case of pure ballistic flow at very low temperature conductance will be quantized in units of $2m^{2}/h$. We show that these steps should be sensitive to increases in temperature. We also use of a random scattering matrix simulation to study flow with diffusive wall scattering. Universal conductance fluctuations analogous to those seen in electron systems should then be observable. Finally we consider the possibility of the cross-over to a one-dimensional system at sufficiently low temperature where the system could form a Luttinger liquid

Information on nutritional supplement labels: time for legislation?

Background: Nutritional supplements have received attention both from food manufacturers, as a means of marketing the added value to health; and from consumers, in terms of awareness, education, and improved health. To assist this process, it is important to have specific knowledge and understanding of the claims made on labels of nutritional supplement products used for general, and more specifically, for sports consumers. The industry is not regulated, and therefore the claims that are made may not always be accurate.Method: The aim was to describe the labelling and claims information on the labels of a select group of nutritional supplements, either manufactured in, or imported into South Africa. Specific predetermined categories of labelling and claims made on the containers were assessed and summarised.Results: Forty products were selected for analysis, of which 21 (53%) were locally assembled or manufactured products, and 19 (48%), international imported products. Ninety-five per cent of products contained a warning statement on the label. Eighty-five per cent of the nutritional supplement products had a disclaimer on the label. Ninety-eight per cent of the nutritional supplement product labels included some claim on the label.Conclusion: The following information, in particular, needs to be regulated and enforced as part of the labelling process, to ensure that the consumer can make an informed choice. This includes highlighting the potential for adverse events, encouraging warning statements pertaining to “exclusion of use, and “not a cure for disease states”, and alerting consumers of the potential for the presence of banned substances, based on laboratory screen methods.Keywords: nutritional, supplements, contaminants, claims, legislation, labellin

Suppression of Giant Magnetoresistance by a superconducting contact

We predict that current perpendicular to the plane (CPP) giant magnetoresistance (GMR) in a phase-coherent magnetic multilayer is suppressed when one of the contacts is superconducting. This is a consequence of a superconductivity-induced magneto-resistive (SMR) effect, whereby the conductance of the ferromagnetically aligned state is drastically reduced by superconductivity. To demonstrate this effect, we compute the GMR ratio of clean (Cu/Co)_nCu and (Cu/Co)_nPb multilayers, described by an ab-initio spd tight binding Hamiltonian. By analyzing a simpler model with two orbitals per site, we also show that the suppression survives in the presence of elastic scattering by impurities.Comment: 5 pages, 4 figures. Submitted to PR

Precision of the determination of focal depth from the spectral ratio of Love/Rayleigh surface waves

The precision with which the focal depth may be determined using Love/Rayleigh-wave spectral ratios depends on the accuracy of the models for Earth structure and for source mechanism used in the focal depth calculations. Estimates of the precision of the focal depth determination are obtained using the partial derivatives of Love/Rayleigh spectral ratios with respect to the parameters: focal depth, shear velocity, dip angle, and slip angle. We find that errors caused by imprecise knowledge of any of these parameters can be important in practice

Host immune response and pathological expression in malaria: possible implications for malaria vaccines

Recent progress in parasite immunobiology has led to the identification of several plasmodial antigens representing the target of the protective antibody response of the infected host. As a consequence, some of these antigens have been envisaged as potential malaria vaccines in man. However, in spite of these achievements, the fine mechanisms which lead to the development of a state of partial protective immunity or to the triggering of immunopathology during malaria infection are not yet fully understood. Thus, it may be appropriate to evaluate the relative importance of individual host immune responsiveness to parasite epitopes involved in the induction of immunity, or of some immunologically mediated adverse reactions such as glomerulonephritis, anaemia, thrombocytopenia, and cerebral syndrom

Diagnostic accuracy of a brief screening tool forAttention Deficit/Hyperactivity Disorder in UK prison inmates

BackgroundAttention deficit hyperactivity disorder (ADHD) is overrepresented in prison, making it imperative to identify a screening tool that can be quickly applied to efficiently detect the disorder. We explored the discrimination ability of a widely used ADHD screen, the Barkley Adult ADHD Rating Scale (BAARS-IV), against a clinical diagnostic interview. A brief version of the screen was then developed in order to simplify its use in the prison context, and maximize its diagnostic properties.MethodA cross-sectional study of 390 male prison inmates was performed in the UK, all participants were screened and interviewed via the Diagnostic Interview for ADHD in Adults 2.0 (DIVA-2).ResultsA total of 47 (12.1%) inmates screened positive for ADHD using the full BAARS-IV, and 96 (24.6%) were clinically diagnosed, for a sensitivity of 37.9 and a specificity of 96.3. Our models identified the six items that most predicted ADHD diagnosis, with adjusted odds ratios ranging from 2.66 to 4.58. Sensitivity, specificity and accuracy were 0.82, 0.84 and 0.84, respectively, for the developed brief scale, and 0.71, 0.85 and 0.81 for its validation. Weighted probability scores produced an area under the curve of 0.89 for development, and 0.82 for validation of the brief scale.ConclusionsThe original BAARS-IV performed poorly at identifying prison inmates with ADHD. Our developed brief scale substantially improved diagnostic accuracy. The brief screening instrument has great potential to be used as an accurate and resource-effective tool to screen young people and adults for likely ADHD in the criminal justice system.</jats:sec

Superconducting Proximity Effect and Universal Conductance Fluctuations

We examine universal conductance fluctuations (UCFs) in mesoscopic normal-superconducting-normal (N-S-N) structures using a numerical solution of the Bogoliubov - de Gennes equation. We discuss two cases depending on the presence (``open'' structure) or absence (``closed'' structure) of quasiparticle transmission. In contrast to N-S structures, where the onset of superconductivity increases fluctuations, we find that UCFs are suppressed by superconductivity for N-S-N structures. We demonstrate that the fluctuations in ``open'' and ``closed'' structures exhibit distinct responses to an applied magnetic field and to an imposed phase variation of the superconducting order parameter.Comment: (4 pages, 5 figures). Corrected typos in equations, added references, changed Fig. 5 and its discussions. Phys. Rev. B, accepted for publicatio

Probing electron acceleration and X-ray emission in laser-plasma accelerator

While laser-plasma accelerators have demonstrated a strong potential in the acceleration of electrons up to giga-electronvolt energies, few experimental tools for studying the acceleration physics have been developed. In this paper, we demonstrate a method for probing the acceleration process. A second laser beam, propagating perpendicular to the main beam is focused in the gas jet few nanosecond before the main beam creates the accelerating plasma wave. This second beam is intense enough to ionize the gas and form a density depletion which will locally inhibit the acceleration. The position of the density depletion is scanned along the interaction length to probe the electron injection and acceleration, and the betatron X-ray emission. To illustrate the potential of the method, the variation of the injection position with the plasma density is studied