67 research outputs found

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    Minimally invasive transforaminal lumbar interbody fusion (MIS TLIF): 2 year prospective outcome study in a tertiary care hospital

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    MIS TLIF is a safe and effective technique in our prospective clinical study of 91 patients that achieved good to excellent clinical outcomes above the expectations of the patient. All patients showed significant improvements in their ODI, VAS score, and SF-36 domains at every time point studied that was maintained up to 24 months. Once radiological healing takes place, the patients have a steady uphill course towards improved functional recovery and reduced pain

    Understanding the Paradox of Information Systems (IS) Case Studies

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    This research aims to understand the mediating roles of learning engagement, learning process, learning experience and their impacts towards students’ learning outcomes through case study pedagogy. Using data collected from the 2013 cohort of Information Systems (IS) classes at RMIT University Vietnam, findings were based on students’ responses to survey items on whether localized real case studies have positive influence on student engagement (in skill, emotional, participation, and performance), learning process (students’ approach on knowledge), and learning experience (students’ opinion on feedback from classmates and lecturer). The research further explored how these mediators affect students’ learning outcomes in group performance and individual’s perceptions of group learning. Structural equation modeling was used to test the causal model. Analysis revealed that case knowledge and case perception had positive influences on students’ skill and emotional engagement. However, only case knowledge had a positive impact on the functions of feedback

    Prevalence of antibiotic resistance genes and genetic relationship of Escherichia coli serotype O45, O113, O121, and O157 isolated from cattle in the Mekong Delta, Vietnam

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    A total of 39 Escherichia coli strains serotype O45, O113, O121, and O157 isolated from cattle in the Mekong Delta were examined the antimicrobial susceptibility to 13 antibiotics by the disc-diffusion method. Those strains were also analyzed for the presence of antibiotic resistance genes by PCR assay, and their genetic relationship by ERIC-PCR assay. The results of antimicrobial susceptibility testing showed that those strains were sensitive to most of the examined antibiotics, but were relatively high resistance to ampicillin (64.10%), and colistin (53.85%). Those E. coli strains could be resistant against one to eight antibiotics with 22 resistance patterns obtained. Moreover, those E. coli strains harbored one to seven antibiotic resistance genes. Gene tetA (51.28%) and blaampC (48.72%) were detected frequently while gene tetB, blaCMY, and cat1 were not found in those E. coli strains. A total of 21 combined patterns of antibiotic resistance genes were recorded, and the most frequent combined pattern was blaampC+tetA (12.82%). ERIC-PCR analysis revealed that each E. coli serotype exhibited various genetic patterns with 40%-100% of similarity. The most elevated number of patterns were in E. coli O157 (nine patterns), followed by E. coli O121 (six patterns). The prevalence of antibiotic resistance genes and diverse genetic characteristics in those E. coli strains originated from cattle constitute potential risks to local health in the Mekong Delta

    Impact of cardiac arrest centers on the survival of patients with nontraumatic out‐of‐hospital cardiac arrest : a systematic review and meta‐analysis

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    Background The role of cardiac arrest centers (CACs) in out‐of‐hospital cardiac arrest care systems is continuously evolving. Interpretation of existing literature is limited by heterogeneity in CAC characteristics and types of patients transported to CACs. This study assesses the impact of CACs on survival in out‐of‐hospital cardiac arrest according to varying definitions of CAC and prespecified subgroups. Methods and Results Electronic databases were searched from inception to March 9, 2021 for relevant studies. Centers were considered CACs if self‐declared by study authors and capable of relevant interventions. Main outcomes were survival and neurologically favorable survival at hospital discharge or 30 days. Meta‐analyses were performed for adjusted odds ratio (aOR) and crude odds ratios. Thirty‐six studies were analyzed. Survival with favorable neurological outcome significantly improved with treatment at CACs (aOR, 1.85 [95% CI, 1.52–2.26]), even when including high‐volume centers (aOR, 1.50 [95% CI, 1.18–1.91]) or including improved‐care centers (aOR, 2.13 [95% CI, 1.75–2.59]) as CACs. Survival significantly increased with treatment at CACs (aOR, 1.92 [95% CI, 1.59–2.32]), even when including high‐volume centers (aOR, 1.74 [95% CI, 1.38–2.18]) or when including improved‐care centers (aOR, 1.97 [95% CI, 1.71–2.26]) as CACs. The treatment effect was more pronounced among patients with shockable rhythm ( P =0.006) and without prehospital return of spontaneous circulation ( P =0.005). Conclusions were robust to sensitivity analyses, with no publication bias detected. Conclusions Care at CACs was associated with improved survival and neurological outcomes for patients with nontraumatic out‐of‐hospital cardiac arrest regardless of varying CAC definitions. Patients with shockable rhythms and those without prehospital return of spontaneous circulation benefited more from CACs. Evidence for bypassing hospitals or interhospital transfer remains inconclusive

    International Consensus Statement on Rhinology and Allergy: Rhinosinusitis

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    Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR‐RS‐2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence‐based findings of the document. Methods: ICAR‐RS presents over 180 topics in the forms of evidence‐based reviews with recommendations (EBRRs), evidence‐based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICAR‐RS‐2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence‐based management algorithm is provided. Conclusion: This ICAR‐RS‐2021 executive summary provides a compilation of the evidence‐based recommendations for medical and surgical treatment of the most common forms of RS

    Generative Design with solidThinking Inspire

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    This thesis presents a computational method generating 3D models based on topology optimization named solidThinking Inspire. The generative modeling procedure is launched with a set of objective conditions and an initial frame. Basing on the prescribed constraints, the program will produce a new shape for 3D model that has optimal perfor-mance, mass-reduction and incredible structure. The technique perfectly inspires all de-signers to disrupt all the baselines of ordinary modelling. In the thesis, there are analytical comparisons about modelling methods and physical re-sults between solidThinking Inspire and SolidWorks. The 3D models will be designed in SolidWorks. Then solidThinking Inspire will operate the optimization process. MakerBot Replicator+ and Formlabs Form 2 in Arcada lab are two 3D printers being used to print out the prototypes. From the optimizing results, it is clear that the solidThinking Inspire is able to transform a design with diminished weight and unchanging performance. Howev-er, It can be concluded that solidThinking Inspire 2016 currently should be utilized as an add-in for other 3D CAD software. Because there is a lack of technical delicacy during sufficing the optimizing shape. In some particular designs, this limit will induce flawed final prototypes
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