This research aims to understand the mediating roles of learning engagement, learning process, learning experience and their impacts towards students’ learning outcomes through case study pedagogy. Using data collected from the 2013 cohort of Information Systems (IS) classes at RMIT University Vietnam, findings were based on students’ responses to survey items on whether localized real case studies have positive influence on student engagement (in skill, emotional, participation, and performance), learning process (students’ approach on knowledge), and learning experience (students’ opinion on feedback from classmates and lecturer). The research further explored how these mediators affect students’ learning outcomes in group performance and individual’s perceptions of group learning. Structural equation modeling was used to test the causal model. Analysis revealed that case knowledge and case perception had positive influences on students’ skill and emotional engagement. However, only case knowledge had a positive impact on the functions of feedback