168 research outputs found
Bridging Proper Orthogonal Decomposition methods and augmented Newton-Krylov algorithms: an adaptive model order reduction for highly nonlinear mechanical problems
This article describes a bridge between POD-based model order reduction
techniques and the classical Newton/Krylov solvers. This bridge is used to
derive an efficient algorithm to correct, "on-the-fly", the reduced order
modelling of highly nonlinear problems undergoing strong topological changes.
Damage initiation problems are addressed and tackle via a corrected
hyperreduction method. It is shown that the relevancy of reduced order model
can be significantly improved with reasonable additional costs when using this
algorithm, even when strong topological changes are involved
A Framework for Robust A Posteriori Error Control in Unsteady Nonlinear Advection-Diffusion Problems
A three-scale domain decomposition method for the 3D analysis of debonding in laminates
The prediction of the quasi-static response of industrial laminate structures
requires to use fine descriptions of the material, especially when debonding is
involved. Even when modeled at the mesoscale, the computation of these
structures results in very large numerical problems. In this paper, the exact
mesoscale solution is sought using parallel iterative solvers. The LaTIn-based
mixed domain decomposition method makes it very easy to handle the complex
description of the structure; moreover the provided multiscale features enable
us to deal with numerical difficulties at their natural scale; we present the
various enhancements we developed to ensure the scalability of the method. An
extension of the method designed to handle instabilities is also presented
Model reduction by separation of variables: A comparison between hierarchical model reduction and proper generalized decomposition
Hierarchical Model reduction and Proper Generalized Decomposition both exploit separation of variables to perform a model reduction. After setting the basics, we exemplify these techniques on some standard elliptic problems to highlight pros and cons of the two procedures, both from a methodological and a numerical viewpoint
Enhanced error estimator based on a nearly equilibrated moving least squares recovery technique for FEM and XFEM
In this paper a new technique aimed to obtain accurate estimates of the error
in energy norm using a moving least squares (MLS) recovery-based procedure is
presented. We explore the capabilities of a recovery technique based on an
enhanced MLS fitting, which directly provides continuous interpolated fields,
to obtain estimates of the error in energy norm as an alternative to the
superconvergent patch recovery (SPR). Boundary equilibrium is enforced using a
nearest point approach that modifies the MLS functional. Lagrange multipliers
are used to impose a nearly exact satisfaction of the internal equilibrium
equation. The numerical results show the high accuracy of the proposed error
estimator
Australia's Oldest Marsupial Fossils and their Biogeographical Implications
Background: We describe new cranial and post-cranial marsupial fossils from the early Eocene Tingamarra Local Fauna in Australia and refer them to Djarthia murgonensis, which was previously known only from fragmentary dental remains. Methodology/Principal Findings: The new material indicates that Djarthia is a member of Australidelphia, a pan-Gondwanan clade comprising all extant Australian marsupials together with the South American microbiotheres. Djarthia is therefore the oldest known crown-group marsupial anywhere in the world that is represented by dental, cranial and postcranial remains, and the oldest known Australian marsupial by 30 million years. It is also the most plesiomorphic known australidelphian, and phylogenetic analyses place it outside all other Australian marsupials. Conclusions/Significance: As the most plesiomorphic and oldest unequivocal australidelphian, Djarthia may approximate the ancestral morphotype of the Australian marsupial radiation and suggests that the South American microbiotheres may be the result of back-dispersal from eastern Gondwana, which is the reverse of prevailing hypotheses
Vicinal Surface with Langmuir Adsorption: A Decorated Restricted Solid-on-solid Model
We study the vicinal surface of the restricted solid-on-solid model coupled
with the Langmuir adsorbates which we regard as two-dimensional lattice gas
without lateral interaction. The effect of the vapor pressure of the adsorbates
in the environmental phase is taken into consideration through the chemical
potential. We calculate the surface free energy , the adsorption coverage
, the step tension , and the step stiffness by
the transfer matrix method combined with the density-matrix algorithm. Detailed
step-density-dependence of and is obtained. We draw the roughening
transition curve in the plane of the temperature and the chemical potential of
adsorbates. We find the multi-reentrant roughening transition accompanying the
inverse roughening phenomena. We also find quasi-reentrant behavior in the step
tension.Comment: 7 pages, 12 figures (png format), RevTeX 3.1, submitted to Phys. Rev.
ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery.
It is generally believed that environmental or cutaneous bacteria are the main origin of surgical infections. Therefore, measures to prevent postoperative infections focus on optimizing hygiene and improving asepsis and antisepsis. In a large cohort of patients with infections following major surgery, we identified that the causative bacteria are mainly of intestinal origin. Postoperative infections of intestinal origin were also found in mice undergoing partial hepatectomy. CCR6+ group 3 innate lymphoid cells (ILC3s) limited systemic bacterial spread. Such bulwark function against host invasion required the production of interleukin-22 (IL-22), which controlled the expression of antimicrobial peptides in hepatocytes, thereby limiting bacterial spread. Using genetic loss-of-function experiments and punctual depletion of ILCs, we demonstrate that the failure to restrict intestinal commensals by ILC3s results in impaired liver regeneration. Our data emphasize the importance of endogenous intestinal bacteria as a source for postoperative infection and indicate ILC3s as potential new targets
- …