Types of abuse and risk factors associated with elder abuse

PRINCIPLES Detecting elder abuse is challenging because it is a taboo, and many cases remain unreported. This study aimed to identify types of elder abuse and to investigate its associated risk factors. METHODS Retrospective analyses of 903 dossiers created at an Independent Complaints Authority for Old Age in the Canton of Zurich, Switzerland, from January 1, 2008 to October 31, 2012. Characteristics of victims and perpetrators, types of abuse, and associated risk factors related to the victim or the perpetrator were assessed. Bi- and multivariate analysis were used to identify abuse and neglect determinants. RESULTS A total of 150 cases reflected at least one form of elder abuse or neglect; 104 cases were categorised as abuse with at least one type of abuse (overall 135 mentions), 46 cases were categorised as neglect (active or passive). Psychological abuse was the most reported form (47%), followed by financial (35%), physical (30%) and anticonstitutional abuse (18%). In 81% of the 150 cases at least two risk factors existed. In 13% no associated risk factor could be identified. Compared with neglect, elders with abuse were less likely to be a nursing home resident than living at home (odds ratio [OR] 0.02, 95% confidence interval [CI] 0.00-0.19). In addition, they were more likely to be cohabiting with their perpetrators (OR 18.01, 95% CI 4.43-73.19). CONCLUSION For the majority of the reported elder abuse cases at least two associated risk factors could be identified. Knowledge about these red flags and a multifaceted strategy are needed to identify and prevent elder abuse

Mamiferos da Fazenda Nhumirim, sub-região de Nhecolándia, Pantanal do Mato Grosso do Sul : I - levantamento preliminar de espécies

Trabalho conduzido na Fazenda Nhumirim, Centro de Pesquisa Agropecuária do Pantanal, EMBRAPA, com auxílio da OEA - Organização dos Estados Americanos, através do CNPq, fornecido ao Dr. Cleber J.R. Alho (Conta nº 03-85-528-517-BR-1)The pantanal is one of the world's richest freshwater wetlands. The pantanal is located in the flood plain of the headwaters of the Paraguai river, covering 140,000km2. The habitats of the Pantanal are present in a complex mosaic. The major habitat types are: pockets of forests, called capão or cordilheira, seasonally flooded grasslands or campos, and permanent or temporary lagoons, called baías. The Pantanal harbors both rich and abundant mammal fauna. A survey was conducted at Fazenda Nhumirim, a research station run by the Centro de Pesquisa Agropecuária do Pantanal (CPAP) in Corumbá, a research branch of EMBRAPA. The Fazenda covers an area of 4,310 ha in the sub-region of Nhecolândia, appoximately 150km east of Corumbá, Mato Grosso do Sul. The area receives an average annual rainfall of 1,022mm, and has a mean monthly temperature that varies between 29.1ºC (January) and 22.0ºC (June). Four routes were followed between two times during ten days of each month. The survey routes were covered on horseback by between two and four observers. Each route was followed and equal number of times in the morning and in the afternoon, to eliminate bias related to the activity patterns of mammals. In order to evaluate relative abundance of nocturnal species, we also conducted a number of nocturnal censuses. These censuses were done by car; a high intensity searchlight was used to spot the animals. We also conducted a trap-mark-recapture survey of the small mammals at Fazenda Nhumirim. After the census period, we continued to collect observations on the occurrence of mammals at the Fazenda, noting wherever possible the kind of habitat in which the animals were observed. The survey identified a diversity of mammals at Fazenda Nhumirim: six orders, 14 families, 19 genera, and 20 species. Nasua nasua was the most frequently observed species during the diurnal census, accounting for 61.5 percent of all observations. Dusicyon (formely Cerdocyon) thous was the most frequently observed species on the nocturnal census (39.13%). The small mammal community of Fazenda Nhumirim is composed of seven species: one marsupial, four cricetine rodents and two echimyid rodents

Disconnect within Agriculture and Ecosystem Climate Effects, Adaptations and Policy

Frequently, agriculture and ecosystems (AE) are seen as separate entities, causing entity specific solutions in response to threats. Anthropogenic climate change simultaneously stresses both agriculture and ecosystems along with their interactions. Induced increasing surface temperatures [1], altered precipitation [2], drought intensification [3], altered ground and surface water quantity/quality [4,5], and diminished soil moisture [6] force adaptations for AE, but these adaptations fail to be efficient when interdependencies are not considered. Additional adaptations will be necessary, as future projections anticipate even greater climate change [1]

Genomic diversity of pathogenic Escherichia coli of the EHEC 2 clonal complex

BACKGROUND: Evolutionary analyses of enterohemorrhagic Escherichia coli (EHEC) have identified two distantly related clonal groups: EHEC 1, including serotype O157:H7 and its inferred ancestor O55:H7; and EHEC 2, comprised of several serogroups (O26, O111, O118, etc.). These two clonal groups differ in their virulence and global distribution. Although several fully annotated genomic sequences exist for strains of serotype O157:H7, much less is known about the genomic composition of EHEC 2. In this study, we analyzed a set of 24 clinical EHEC 2 strains representing serotypes O26:H11, O111:H8/H11, O118:H16, O153:H11 and O15:H11 from humans and animals by comparative genomic hybridization (CGH) on an oligoarray based on the O157:H7 Sakai genome. RESULTS: Backbone genes, defined as genes shared by Sakai and K-12, were highly conserved in EHEC 2. The proportion of Sakai phage genes in EHEC 2 was substantially greater than that of Sakai-specific bacterial (non-phage) genes. This proportion was inverted in O55:H7, reiterating that a subset of Sakai bacterial genes is specific to EHEC 1. Split decomposition analysis of gene content revealed that O111:H8 was more genetically uniform and distinct from other EHEC 2 strains, with respect to the Sakai O157:H7 gene distribution. Serotype O26:H11 was the most heterogeneous EHEC 2 subpopulation, comprised of strains with the highest as well as the lowest levels of Sakai gene content conservation. Of the 979 parsimoniously informative genes, 15% were found to be compatible and their distribution in EHEC 2 clustered O111:H8 and O118:H16 strains by serotype. CGH data suggested divergence of the LEE island from the LEE1 to the LEE4 operon, and also between animal and human isolates irrespective of serotype. No correlation was found between gene contents and geographic locations of EHEC 2 strains. CONCLUSION: The gene content variation of phage-related genes in EHEC 2 strains supports the hypothesis that extensive modular shuffling of mobile DNA elements has occurred among EHEC strains. These results suggest that EHEC 2 is a multiform pathogenic clonal complex, characterized by substantial intra-serotype genetic variation. The heterogeneous distribution of mobile elements has impacted the diversification of O26:H11 more than other EHEC 2 serotypes

Partners in biodiversity science and policy

The development of standards, data sharing, and initiatives like the Global Biodiversity Information Facility and others have advanced research in many fields, including in conservation of biodiversity. Global assessments of extinction risk to species have been completed by IUCN for multiple taxa. The IUCN global assessments have had a major impact on conservation science and practice as well as biodiversity funding mechanisms though the Global Environment Facility, the World Bank, and the Critical Ecosystem Partnership Fund (CEPF). A signature of the assessments is a process of sustained interaction between conservation organizations and the research and academic community, effectively integrating science and policy on global scale. The model relies on several critical components: openness of the conservation community to scientific input and debate, engagement of the scientific community, conservation organization mediated data collation, and data sharing with ease of access. This model can be applied to other challenges to conserve biodiversity and assess how biodiversity loss affects the well-being of societies across the world. The recognition of the importance of biodiversity in meeting the Millennium Development Goals and the recognition of the failure to meet the 2010 Biodiversity Target illustrate the gap between what needs to be achieved and our current trajectory

Large and medium-sized mammals in the urban park Cinturão Verde, Cianorte, northwestern Paraná

We surveyed the composition of large and medium-sized mammals in the urban park Cinturão Verde in the city of Cianorte, Paraná, Brazil. This urban reserve is an important regional corridor for wildlife. Data were collected monthly during seven months for six days with track plots, camera traps, and visual searches for animals and sign. Richness estimates were calculated using Chao 2 and ICE estimators. Nineteen species of mammals in seven orders and 14 families were recorded. Although the area displays a high degree of disturbance, it supports the presence of important species for the fauna of northwestern Paraná, including state, regional and globally threatened species

Increased Adherence and Expression of Virulence Genes in a Lineage of Escherichia coli O157:H7 Commonly Associated with Human Infections

Enterohemorrhagic Escherichia coli (EHEC) O157:H7, a food and waterborne pathogen, can be classified into nine phylogenetically distinct lineages, as determined by single nucleotide polymorphism genotyping. One lineage (clade 8) was found to be associated with hemolytic uremic syndrome (HUS), which can lead to kidney failure and death in some cases, particularly young children. Another lineage (clade 2) differs considerably in gene content and is phylogenetically distinct from clade 8, but caused significantly fewer cases of HUS in a prior study. Little is known, however, about how these two lineages vary with regard to phenotypic traits important for disease pathogenesis and in the expression of shared virulence genes.Here, we quantified the level of adherence to and invasion of MAC-T bovine epithelial cells, and examined the transcriptomes of 24 EHEC O157:H7 strains with varying Shiga toxin profiles from two common lineages. Adherence to epithelial cells was >2-fold higher for EHEC O157:H7 strains belonging to clade 8 versus clade 2, while no difference in invasiveness was observed between the two lineages. Whole-genome 70-mer oligo microarrays, which probe for 6088 genes from O157:H7 Sakai, O157:H7 EDL 933, pO157, and K12 MG1655, detected significant differential expression between clades in 604 genes following co-incubation with epithelial cells for 30 min; 186 of the 604 genes had a >1.5 fold change difference. Relative to clade 2, clade 8 strains showed upregulation of major virulence genes, including 29 of the 41 locus of enterocyte effacement (LEE) pathogenicity island genes, which are critical for adherence, as well as Shiga toxin genes and pO157 plasmid-encoded virulence genes. Differences in expression of 16 genes that encode colonization factors, toxins, and regulators were confirmed by qRT-PCR, which revealed a greater magnitude of change than microarrays.These findings demonstrate that the EHEC O157:H7 lineage associated with HUS expresses higher levels of virulence genes and has an enhanced ability to attach to epithelial cells relative to another common lineage

Integrating Agriculture and Ecosystems to Find Suitable Adaptations to Climate Change

Climate change is altering agricultural production and ecosystems around the world. Future projections indicate that additional change is expected in the coming decades, forcing individuals and communities to respond and adapt. Current research efforts typically examine climate change effects and possible adaptations but fail to integrate agriculture and ecosystems. This failure to jointly consider these systems and associated externalities may underestimate climate change impacts or cause adaptation implementation surprises, such as causing adaptation status of some groups or ecosystems to be worsened. This work describes and motivates reasons why ecosystems and agriculture adaptation require an integrated analytical approach. Synthesis of current literature and examples from Texas are used to explain concepts and current challenges. Texas is chosen because of its high agricultural output that is produced in close interrelationship with the surrounding semi-arid ecosystem. We conclude that future effect and adaptation analyses would be wise to jointly consider ecosystems and agriculture. Existing paradigms and useful methodology can be transplanted from the sustainable agriculture and ecosystem service literature to explore alternatives for climate adaptation and incentivization of private agriculturalists and consumers. Researchers are encouraged to adopt integrated modeling as a means to avoid implementation challenges and surprises when formulating and implementing adaptation

Enteropathogenic Escherichia coli O157 Strains from Brazil

We describe two serogroup O157 Escherichia coli strains from Brazilian infants with diarrhea. A variety of assays indicate that these strains belong to the enteropathogenic, not the enterohemorrhagic, pathotype. These strains possess a novel bfpA allele encoding the type IV pilin characteristic of typical enteropathogenic E. coli strains. Our results emphasize the pitfalls of classifying pathogenic E. coli by serogroup