Current Developments in Intraspinal Agents for Cancer and Noncancer Pain

Since the late 1980s, intrathecal (IT) analgesic therapy has improved, and implantable IT drug delivery devices have become increasingly sophisticated. Physicians and patients now have myriad more options for agents and their combination, as well as for refining their delivery. As recently as 2007, The Polyanalgesic Consensus Conference of expert panelists updated its algorithm for drug selection in IT polyanalgesia. We review this algorithm and the emerging therapy included. This article provides an update on newly approved as well as emerging IT agents and the advances in technology for their delivery

Bandwidth Estimation for Admission Control in MANET: Review and Conceptual MANET Admission Control Framework

The widespread of wireless mobile network have increased the demand for its applications. Providing a reliable QoS in wireless medium, especially mobile ad-hoc network (MANET), is quite challenging and remains an ongoing research trend. One of the key issues of MANET is its inability to accurately predict the needed and available resources to avoid interference with already transmitting traffic flow. In this work, we propose a resource allocation and admission control (RAAC) solution. RAAC is an admission control scheme that estimates the available bandwidth needed within a network, using a robust and accurate resource estimation technique. Simulation results obtained show that our proposed scheme for MANET can efficiently estimate the available bandwidth and outperforms other existing approaches for admission control with bandwidth estimation

Behavioral genetics and taste

This review focuses on behavioral genetic studies of sweet, umami, bitter and salt taste responses in mammals. Studies involving mouse inbred strain comparisons and genetic analyses, and their impact on elucidation of taste receptors and transduction mechanisms are discussed. Finally, the effect of genetic variation in taste responsiveness on complex traits such as drug intake is considered. Recent advances in development of genomic resources make behavioral genetics a powerful approach for understanding mechanisms of taste

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

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Effect of scaling parameters on waterflood performance with horizontal and vertical wells

This paper presents numerical study on the effect of scaling parameters on the waterflood performance with different well configurations. The oil recoveries obtained from experiments on a laboratory scale model have been compared with those obtained from a model, which is scaled up using scaling relationships which are in the form of dimensionless numbers. The effects of dimensionless scaling groups like effective aspect ratio, mobility ratio, buoyancy number, and capillary number on breakthrough oil recovery (BOR) with four different well configurations, viz., vertical injection-vertical production (VI-VP), vertical injection-horizontal production at top (VI-HPT), vertical injection-horizontal production at bottom (VI-HPB), and horizontal injection at bottom-horizontal production at top (HIB-HPT), are reported. It is found that the HIB-HPT well configuration gives higher oil recovery and that VI-HPB gives lower recovery than other well configurations under most of the conditions considered. For higher buoyancy numbers, all configurations result in lower BOR values except VI-HPT, which leads to a higher BOR. However, the performance of other well configurations is also comparable to that of HIB-HPT under certain conditions