11 research outputs found

    Gender differences in the use of cardiovascular interventions in HIV-positive persons; the D:A:D Study

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    Scientifically unfounded precaution drives European Commission's recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles

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    We, the undersigned editors of prominent journals of pharmacology and toxicology, are drawing your attention to the imminent decisions by the European Commission to enforce a regulatory framework for so-called endocrine disrupting chemicals (EDCs). The currently drafted framework is based on virtually complete ignorance of all well-established and taught principles of pharmacology and toxicology, of opinions raised by the European Commission’s own competent expert authority (European Food Safety Authority (EFSA, 2013)), and of critical statements made by member countries, while avoiding asking for support from the European Commission’s own scientific expert committees

    Cumulative and current exposure to potentially nephrotoxic antiretrovirals and development of chronic kidney disease in HIV-positive individuals with a normal baseline estimated glomerular filtration rate: A prospective international cohort study

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    Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

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    These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in murine and human cells. The latest flow cytometry techniques and applications are also described, featuring examples of the data that can be generated and, importantly, how the data can be analysed. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid, all written and peer-reviewed by leading experts in the field, making this an essential research companion

    Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

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    Monoclonal antibody therapy

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