229 research outputs found
Language difficulties in first year Science
A key goal of the study entitled ‘A cross-disciplinary approach to language support for first year students in the science disciplines’, funded by the Carrick Institute for Learning and Teaching in Higher Education, is to examine the role of language in the learning of science by first-year university students. The disciplines involved are Physics, Chemistry and Biology. This national project also aims to transfer active learning skills, which are widely used in language teaching, to the teaching of science in first year. The paper discusses the background to the study, reports on some of the preliminary results on the language difficulties faced by first year student cohorts in science from data collected in 2008, and describes the framework we have established for the organization and delivery of first year science courses to be implemented in semester one 2009
Integrating language learning practises in first year science disciplines
Student retention and progression rates are a matter of concern for most institutions in the higher education sector (Burton & Dowling, 2005;. Simpson, 2006;. Tinto & Pusser, 2006) in Australia. There is also a substantial body of literature concentrating on the first year experience at university (for example, in the Australian context, see Krause, Hartley, James, McInnis, & Centre for the Study of Higher Education. University of Melbourne, 2005). One of the particular concerns is that the diversity of the student body is rapidly increasing. Of course, with diversity comes with differentiated level of preparation for academic study within the student body
Embedding in-discipline language support for first year students in the sciences
This paper reports on a project which aims at addressing the need to cater for the language needs of a diverse student body (both domestic and international student body) by embedding strategic approaches to learning and teaching in first year sciences in tertiary education. These strategies consist of active learning skills which are widely used in language learning. The disciplines covered by the project are Biology, Chemistry and Physics and involves the University of Canberra (UC), University of Sydney (USyd), University of Tasmania (UTAS), University of Technology, Sydney (UTS) and University of Newcastle (Newcastle) in Australia. This project is funded by the Australian Learning and Teaching Council (ALTC). The paper discusses the background to the study and reports on results on the language difficulties faced by first year science student cohorts from data collected in 2008 as well as qualitative data was also collected on 2008 students’ attitudes towards online science learning. It will also report on the results on the implementation of the learning strategies at UTS and UTAS in Physics and Chemistry disciplines in 2009. Keywords: First year science teaching, role of language in science teaching, active learning skill
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Characterization of the fecal microbiome in cats with inflammatory bowel disease or alimentary small cell lymphoma.
Feline chronic enteropathy (CE) is a common gastrointestinal disorder in cats and mainly comprises inflammatory bowel disease (IBD) and small cell lymphoma (SCL). Both IBD and SCL in cats share features with chronic enteropathies such as IBD and monomorphic epitheliotropic intestinal T-cell lymphoma in humans. The aim of this study was to characterize the fecal microbiome of 38 healthy cats and 27 cats with CE (13 cats with IBD and 14 cats with SCL). Alpha diversity indices were significantly decreased in cats with CE (OTU p = 0.003, Shannon Index p = 0.008, Phylogenetic Diversity p = 0.019). ANOSIM showed a significant difference in bacterial communities, albeit with a small effect size (P = 0.023, R = 0.073). Univariate analysis and LEfSE showed a lower abundance of facultative anaerobic taxa of the phyla Firmicutes (families Ruminococcaceae and Turicibacteraceae), Actinobacteria (genus Bifidobacterium) and Bacteroidetes (i.a. Bacteroides plebeius) in cats with CE. The facultative anaerobic taxa Enterobacteriaceae and Streptococcaceae were increased in cats with CE. No significant difference between the microbiome of cats with IBD and those with SCL was found. Cats with CE showed patterns of dysbiosis similar to those in found people with IBD
Liveness-Driven Random Program Generation
Randomly generated programs are popular for testing compilers and program
analysis tools, with hundreds of bugs in real-world C compilers found by random
testing. However, existing random program generators may generate large amounts
of dead code (computations whose result is never used). This leaves relatively
little code to exercise a target compiler's more complex optimizations.
To address this shortcoming, we introduce liveness-driven random program
generation. In this approach the random program is constructed bottom-up,
guided by a simultaneous structural data-flow analysis to ensure that the
generator never generates dead code.
The algorithm is implemented as a plugin for the Frama-C framework. We
evaluate it in comparison to Csmith, the standard random C program generator.
Our tool generates programs that compile to more machine code with a more
complex instruction mix.Comment: Pre-proceedings paper presented at the 27th International Symposium
on Logic-Based Program Synthesis and Transformation (LOPSTR 2017), Namur,
Belgium, 10-12 October 2017 (arXiv:1708.07854
Fecal microbiota in client-owned obese dogs changes after weight loss with a high-fiber-high-protein diet
Background. The fecal microbiota from obese individuals can induce obesity in animal models. In addition, studies in humans, animal models and dogs have revealed that the fecal microbiota of subjects with obesity is different from that of lean subjects and changes after weight loss. However, the impact of weight loss on the fecal microbiota in dogs with obesity has not been fully characterized. Methods. In this study, we used 16S rRNA gene sequencing to investigate the differences in the fecal microbiota of 20 pet dogs with obesity that underwent a weight loss program. The endpoint of the weight loss program was individually tailored to the ideal body weight of each dog. In addition, we evaluated the qPCR based Dysbiosis Index before and after weight loss. Results. After weight loss, the fecal microbiota structure of dogs with obesity changed significantly (weighted ANOSIM; p = 0.016, R = 0.073), showing an increase in bacterial richness (p = 0.007), evenness (p = 0.007) and the number of bacterial species (p = 0.007). The fecal microbiota composition of obese dogs after weight loss was characterized by a decrease in Firmicutes (92.3% to 78.2%, q = 0.001), and increase in Bacteroidetes (1.4% to 10.1%, q = 0.002) and Fusobacteria (1.6% to 6.2%, q = 0.040). The qPCR results revealed an overall decrease in the Dysbiosis Index, driven mostly due to a significant decrease in E. coli (p = 0.030), and increase in Fusobacterium spp. (p = 0.017). Conclusion. The changes observed in the fecal microbiota of dogs with obesity after weight loss with a weight loss diet rich in fiber and protein were in agreement with previous studies in humans, that reported an increase of bacterial biodiversity and a decrease of the ratio Firmicutes/Bacteroidetes
Correlation of intestinal histopathologic findings with mucosa-attached bacteria, clinical disease activity, and clinical outcome in dogs with chronic enteropathies
Peer reviewe
A distinct, high-affinity, alkaline phosphatase facilitates occupation of P-depleted environments by marine picocyanobacteria
Marine picocyanobacteria of the genera Prochlorococcus and Synechococcus, the two most abundant phototrophs on Earth, thrive in oligotrophic oceanic regions. While it is well known that specific lineages are exquisitely adapted to prevailing in situ light and temperature regimes, much less is known of the molecular machinery required to facilitate occupancy of these low-nutrient environments. Here, we describe a hitherto unknown alkaline phosphatase, Psip1, that has a substantially higher affinity for phosphomonoesters than other well-known phosphatases like PhoA, PhoX, or PhoD and is restricted to clade III Synechococcus and a subset of high light I-adapted Prochlorococcus strains, suggesting niche specificity. We demonstrate that Psip1 has undergone convergent evolution with PhoX, requiring both iron and calcium for activity and likely possessing identical key residues around the active site, despite generally very low sequence homology. Interrogation of metagenomes and transcriptomes from TARA oceans and an Atlantic Meridional transect shows that psip1 is abundant and highly expressed in picocyanobacterial populations from the Mediterranean Sea and north Atlantic gyre, regions well recognized to be phosphorus (P)-deplete. Together, this identifies psip1 as an important oligotrophy-specific gene for P recycling in these organisms. Furthermore, psip1 is not restricted to picocyanobacteria and is abundant and highly transcribed in some α-proteobacteria and eukaryotic algae, suggesting that such a high-affinity phosphatase is important across the microbial taxonomic world to occupy low-P environments.</p
The scattering of muons in low Z materials
This paper presents the measurement of the scattering of 172 MeV/c muons in
assorted materials, including liquid hydrogen, motivated by the need to
understand ionisation cooling for muon acceleration.
Data are compared with predictions from the Geant 4 simulation code and this
simulation is used to deconvolute detector effects. The scattering
distributions obtained are compared with the Moliere theory of multiple
scattering and, in the case of liquid hydrogen, with ELMS. With the exception
of ELMS, none of the models are found to provide a good description of the
data. The results suggest that ionisation cooling will work better than would
be predicted by Geant 4.7.0p01.Comment: pdfeTeX V 3.141592-1.21a-2.2, 30 pages with 22 figure
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