10 research outputs found
Selective Serotonin Reuptake Inhibitors and Gastrointestinal Bleeding: A Case-Control Study
- Author
- A Helin-Salmivaara
- Adolfo Figueiras
- Alfonso Carvajal
- Anita Conforti
- AT Remaley
- Borja Ruiz
- BP Skop
- C Barbui
- C van Walraven
- Carmelo Aguirre
- D Bates
- D Layton
- DJ McCloskey
- DM Hougardy
- E Salkeld
- FJ de Abajo
- FJ de Abajo
- FJ de Abajo
- H Brown
- IM Gralnek
- J Kharofa
- James M. Wright
- JC Pinheiro
- JD Lewis
- JJ Ofman
- K Takeuchi
- KJ Rothman
- KL Movig
- L Opatrny
- LE Targownik
- LH Martín Arias
- LJ Tata
- Lourdes Del Olmo
- Luisa Ibáñez
- M Dall
- M Tatsumi
- N Hergovich
- NR Dunn
- Paula López-Vázquez
- Roberto Leone
- S Bak
- S Wessinger
- Sara Ortega
- SO Dalton
- T Ahrens
- T Dickinson
- WE Meijer
- X Vidal
- Xavier Vidal
- Y Chen
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) have been associated with upper gastrointestinal (GI) bleeding. Given their worldwide use, even small risks account for a large number of cases. This study has been conducted with carefully collected information to further investigate the relationship between SSRIs and upper GI bleeding. METHODS: We conducted a case-control study in hospitals in Spain and in Italy. Cases were patients aged ≥18 years with a primary diagnosis of acute upper GI bleeding diagnosed by endoscopy; three controls were matched by sex, age, date of admission (within 3 months) and hospital among patients who were admitted for elective surgery for non-painful disorders. Exposures to SSRIs, other antidepressants and other drugs were defined as any use of these drugs in the 7 days before the day on which upper gastrointestinal bleeding started (index day). RESULTS: 581 cases of upper GI bleeding and 1358 controls were considered eligible for the study; no differences in age or sex distribution were observed between cases and controls after matching. Overall, 4.0% of the cases and 3.3% of controls used an SSRI antidepressant in the week before the index day. No significant risk of upper GI bleeding was encountered for SSRI antidepressants (adjusted odds ratio, 1.06, 95% CI, 0.57-1.96) or for whichever other grouping of antidepressants. CONCLUSIONS: The results of this case-control study showed no significant increase in upper GI bleeding with SSRIs and provide good evidence that the magnitude of any increase in risk is not greater than 2
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
- Abildgaard MH
- Abudu YP
- Acevedo-Arozena A
- Adamopoulos IE
- Adeli K
- Adolph TE
- Adornetto A
- Aflaki E
- Agam G
- Agarwal A
- Aggarwal BB
- Agnello M
- Agostinis P
- Agrewala JN
- Agrotis A
- Aguilar PV
- Ahmad ST
- Ahmed ZM
- Ahumada-Castro U
- Aits S
- Aizawa S
- Akkoc Y
- Akoumianaki T
- Akpinar HA
- Al-Abd AM
- Al-Akra L
- Al-Gharaibeh A
- Alaoui-Jamali MA
- Alberti S
- Alcocer-Gómez E
- Alessandri C
- Ali M
- Alim Al-Bari MA
- Aliwaini S
- Alizadeh J
- Almacellas E
- Almasan A
- Alonso A
- Alonso GD
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- Altieri DC
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- Zambelli VO
- Zanella I
- Zang QS
- Zanivan S
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- Zaragoza P
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- Zarrouk A
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- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X-W
- Zhang XD
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y-D
- Zhang Y-Y
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
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- Zhao H
- Zhao L
- Zhao S
- Zhao T
- Zhao X-F
- Zhao Y
- Zhao Y
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- Zheng G
- Zheng K
- Zheng L
- Zheng S
- Zheng X-L
- Zheng Y
- Zheng Z-G
- Zhivotovsky B
- Zhong Q
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- Zhou X-J
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- Zhou Y
- Zhou Z
- Zhou Z-Y
- Zhu B
- Zhu C
- Zhu G-Q
- Zhu H
- Zhu H
- Zhu H
- Zhu W-G
- Zhu Y
- Zhu Y
- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
- Zou Z
- Zou Z
- Zuryn S
- Zwerschke W
- Álvarez ÉMC
- Ávalos Y
- Önal G
- Üstün S
- Čolić M
- Đokić J
- Žerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Before and after triazolam: changes in the consumption of hypnotics in Spain [letter]
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Heart Rhythm Disturbances Associated With Rupatadine: A Case Series From the Spanish and Portuguese Pharmacovigilance Systems
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Expression of segment polarity genes in brachiopods supports a non-segmental ancestral role of engrailed for bilaterians
- Author
- A Altenburger
- A Asadulina
- A Fjose
- A Hejnol
- A Martinez Arias
- A Martinez-Arias
- A Minelli
- A Stamatakis
- A Untergasser
- AD Chipman
- AM Pani
- B Prud’homme
- C Dahmann
- C Kunick
- C Nielsen
- CBWas Kimmel
- CE Laumer
- CJ Lowe
- CL Hughes
- CP Petersen
- CW Dunn
- D Tautz
- E Abouheif
- E Matsunaga
- EC Seaver
- EC Seaver
- EG Conklin
- EM De Robertis
- EM De Robertis
- EN Temereva
- G Balavoine
- G Freeman
- G Freeman
- G Freeman
- G Freeman
- G Scholtz
- G Scholtz
- G Scholtz
- G Talavera
- GE Budd
- GK Davis
- I Araki
- J Huerta-Cepas
- J Schindelin
- JA Long
- JM Martín-Durán
- JT Cannon
- K Katoh
- K Mellenthin
- K Okonechnikov
- KM Cadigan
- LH Hyman
- LM Nagy
- M Fujioka
- M Rhinn
- N Dray
- N Yatsu
- NH Patel
- PW Ingham
- PW Ingham
- PW Ingham
- S Glardon
- S Scholpp
- T Okafuji
- T Staudt
- T Tabata
- TH Struck
- WGM Damen
- Z Kozmik
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Guillain-Barré syndrome following the 2009 pandemic monovalent and seasonal trivalent influenza vaccination campaigns in Spain from 2009 to 2011: outcomes from active surveillance by a neurologist network, and records from a country-wide hospital discharge database
- Author
- A Forsberg
- AK Asbury
- C Bardage
- C Kim
- Carlos Casasnovas
- Carlos Cemillán
- CN Dodd
- D Funch
- DA Salmon
- DL McClure
- Dolores Montero
- DR Burwen
- Enrique Alcalde-Cabero
- ES Hurwitz
- F Galeotti
- Fernando J. García López
- Francisco Javier Rodríguez-Rivera
- Fuencisla Avellanal
- GP Giambrone
- HJ Whitaker
- J Dieleman
- J Stowe
- J Wu
- Jacinto Duarte
- Javier Almazán-Isla
- JC Kwong
- Jesús de Pedro-Cuesta
- JJ Sejvar
- JL Cuadrado
- JL Cuadrado
- JM Glanz
- José Ignacio Cuadrado
- José Ramón Ara-Callizo
- Juan Antonio García Merino
- Julio Pardo
- K Ulm
- LH Martín Arias
- M Valenciano
- María Dolores Fernández-Pérez
- María Ruiz-Tovar
- N Yuki
- P Wals de
- Q Cheng
- Rosa García Montero
- S Iqbal
- T Lasky
- TJ Safranek
- Óscar Fernández
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Climate change and pollen allergies
- Author
- A Ault
- A Damialis
- A Damialis
- A Ghiani
- A Kelish El
- A Linneberg
- A Linneberg
- A Linneberg
- A Menzel
- A Obersteiner
- A Stach
- Athanasios Damialis
- AZ Sin
- B Crouzy
- B Sibbald
- B Sikoparija
- B Wüthrich
- British Aerobiology Federation
- C Fotiou
- C Galán
- C Kirmaz
- C Parmesan
- C Traidl-Hoffmann
- C Troise
- C Ziello
- D Barber
- D Gioulekas
- D Voukantsis
- DC Dittlein
- DP Strachan
- E Kadocsa
- E Varjonen
- ER Weeke
- F Boralevi
- F Häring
- F Zhao
- F Zhao
- G Loureiro
- GJ Burbach
- H García-Mozo
- I Beck
- IP Erkara
- J Bunne
- J Kaleyias
- J Mandal
- J Oteros
- J Subiza
- JL Brożek
- JTM Buters
- K Bastl
- K. Karatzas
- KC Bergmann
- L Weger de
- LH Ziska
- LP Höhle
- LYF Wu
- M Averbeck
- M Copula
- M Haftenberger
- M Marogna
- M Morais-Almeida
- M Smith
- M Sofiev
- M Verini
- MT Belver
- NJ Osborne
- O Rybníček
- P Wayne
- PG Burney
- PM Cosmes Martín
- R Asero
- R Peternel
- R Treudler
- R Treudler
- RP Wodehouse
- RS Mueller
- RY Lin
- S Brunel
- S Gilles
- S Gilles
- S Gilles-Stein
- S Kawashima
- S Pignatti
- S Voltolini
- S Wan
- T Alfaya Arias
- T Bieber
- T Frei
- TK Ninan
- U Berger
- U Langen
- VN Kobzar
- W Hemmer
- WH Lewis
- Y Nakamaru
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2019
- Field of study
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
- Aawsaj Y
- Abadia M
- Abad‐Gurumeta A
- Abad‐Motos A
- Abassy J
- Abate E
- Abbasov A
- Abbott D
- Abbott Tom EF
- Abdalla M
- Abdeldayem H
- Abdelkabir M
- Abdelkader Salama I
- Abdelkarim M
- Abdelsamed A
- Abdulfattah F
- Abdulwahed E
- Abdur‐Rahman LO
- Abel MK
- Abelevich A
- Abiyere H
- Aboelkassem Ibrahim A
- Aboharp Hasan Z
- Abou Chaar MK
- Abreu da Silva A
- Abubakar A
- Abukhalaf SA
- Abukhalaf Sadi
- Acebes García F
- Achalandabaso Boira M
- Acher A
- Acosta Mérida MA
- Acrich E
- Adam Essa Adam ME
- Adamina M
- Adamina Michel
- Adamina Michel
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Aderombi A
- Adeyeye A
- Adeyeye A
- Adi H
- Adiamah A
- Adisa Adewale
- Afzal MF
- Agapov M
- Agarwal Arnav
- Aggarwal M
- Aghayeva A
- Agilinko J
- Agnes A
- Agostini C
- Agrawal A
- Agrawal N
- Agresta F
- Aguado López H
- Aguiar Júnior S
- Aguilar Gonzalez M
- Ahmed A
- Ahmed A
- Ahmed K
- Ahmed ME
- Ahmed Z
- Ahmeidat A
- Ahn JH
- Aiken T
- Aimé A
- Akalin M
- Akaydin E
- Akbas A
- Akhtar MA
- Akhtar N
- Akhter Rahman MM
- Akin E
- Akkulak Murat
- Akrivou D
- Al Abdallah M
- Al ahmad F
- Al Asadi T
- Al Awwad S
- Al Ayed A
- Al Habes H
- Al Riyami S
- AL Sayed M
- Alaa S
- AlAamer O
- Aladeojebi A
- Alagoa Joao A
- Alakaloko Felix
- Alam F
- Alameer Ehab
- Alamri Alex
- Alanazi F
- Alawneh F
- Albaqami F
- Albertsmeier M
- Albertsmeier Markus
- Alcaide Matas F
- Alconchel F
- Alcázar JA
- Alderson Derek
- Aldokali N
- Aleksić L
- Alemanno G
- Alfaifi J
- Alfieri S
- Alfonso Garcia M
- Algallai M
- Alghamdi M
- Alghuliga A
- Alhamed A
- Alharthi M
- Alhassan N
- Ali karar AA
- Ali Sani S
- Ali AA
- Ali M
- Ali S
- Alishi Y
- Aliyeva Z
- Aljiffry M
- Alkadiki Ghadah Z
- Alkhateb S
- Allue M
- Almaadany Faraj S
- Almassaudi A
- Almeida AC
- Almeida JI
- Almeida‐Reis R
- Almezghwi H
- Almgla N
- Almond Max
- Alnumani T
- Alobaysi S
- Alobeed O
- Alonso de la Fuente N
- Alonso Poza A
- Alonso‐Lamberti L
- Alqahtani D
- Alqannas M
- Alrahawy M
- Alsayadi M
- Alsayadi R
- Alselaim N
- Alser Osaid
- Alshaar Muhammad
- Alshahrani A
- Alshahrani M
- Alshammari S
- Alshareea E
- Alshareef K
- Alsharif F
- Alshryda Sattar
- Alsoufi A
- Alsowaina K
- Altinel Y
- Altintoprak F
- Altom R
- Altomare DF
- Altomi I
- Alurralde C
- Alvarez E
- Alvarez MR
- Alvi A
- Alwarfly S
- Alyami M
- Alzaede S
- Alzahrani A
- Alzamanan M
- Alzeerelhouseini H I. A.
- Al‐Habsi R
- Al‐Kharashi E
- Al‐Khayal K
- Al‐Masri M
- Al‐Mohammad A
- Al‐Naggar H
- Al‐Najjar H
- Al‐Shehari M
- Al‐Slaibi I
- Amaral MJ
- Amira G
- Amorim E
- Amrani L
- Anania G
- Anastasi A
- Andrade R
- Angamuthu N
- Angelou D
- Angenete E
- Angoso‐Clavijo M
- Annamalai S
- Annessi V
- Annicchiarico A
- Anscomb N
- Antic A
- Antonakis P
- Antonopoulou MI
- Anula R
- Aparicio‐López D
- Aprile A
- Arab N
- Aremu M
- Arias‐Amézquita F
- Aribi N
- Aribi S
- Arican C
- Arigoni M
- Arikan AE
- Arkadopoulos N
- Arkani S
- Armao T
- Armatura G
- Arminio A
- Arnaud Alexis P
- Arora A
- Arrowsmith L
- Arslan K
- Arulanantham A
- Arumugam S
- Asaad P
- Ashcroft J
- Ashmore C
- Ashoush F
- Askari A
- Asqalan A
- Athanasakis E
- Athanasiou A
- Atherton R
- Attia D
- Augestad Knut Magne
- Avci EK
- Avellana R
- Aversano A
- Avlund T
- Awad S
- Ayasra F
- Ayasra Faris
- Ayasra Y
- Aydin C
- Ayloor Seshadri R
- Ayorinde J
- Aytac E
- Ayub B
- Ayubi A
- Ayyaz M
- Azab MA
- Azam M
- Azamat İF
- Azevedo C
- Azevedo J
- Azevedo José
- Azevedo P
- Azevedo P
- Azzam AY
- B L
- Babalola O
- Babar MS
- Baca B
- Bacarese‐Hamilton T
- Badahdah F
- Badra R
- Baena Sanfeliu E
- Bagraith K
- Baguley M
- Baig M
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- Lozano Lominchar P
- Lucchini SM
- Luglio G
- Lule H
- Lun EWY
- Lunevicius R
- Lunghi EG
- Lynch N
- Lyons A
- Lázaro A
- López Antoñanzas L
- Löffler Markus W
- Löffler MW
- Löfgren N
- M. elghazaly S
- Maa Albared S
- Maccabe TA
- MacDonald L
- Machado D
- Machado N
- Macina S
- Madani Kia T
- Madani R
- Madonini M
- Maffioli A
- Magee C
- Maghrebi H
- Magowan D
- Mahajan A
- Mahendran V
- Mahmood M
- Mahmoud Ali F
- Mahvi D
- Maida P
- Maiga A
- Maimbo Mayaba
- Majbar AM
- Majkowska A
- Major P
- Major Piotr
- Majrashi S
- Majumdar KS
- Mak TWC
- Malapati H
- Malcolm FL
- Malgras B
- Malibary N
- Mall JW
- Maltinti G
- Manatakis DK
- Manfredelli S
- Manku B
- Mann Harvinder S
- Manrique E
- Manso I
- Manson J
- Mantoglu B
- Manu N
- Maqueda González R
- Marafante C
- Marano A
- Marchbank Adrian
- Marcos‐Santos P
- Marcus Hani J
- Mardare M
- Margalit A
- Mari G
- Marialva J
- Mariani NM
- Marie‐Macron L
- Marinello P
- Marino Cosentino L
- Marino M
- Marino MV
- Markaryan D
- Markovic I
- Markovic V
- Marques R
- Marques T
- Marqueta De Salas M
- Marra AA
- Marra E
- Marreiro A
- Marson Ella J
- Marte G
- Martel A
- Martin E
- Martin E
- Martin Janet
- Martin ST
- Martinek L
- Martinez German A
- Martins dos Santos G
- Martins Jordão D
- Martins A
- Martins D
- Martins R
- Martin‐Perez B
- Martin‐Perez E
- Martín Anoro LF
- Martín L
- Martínez Chicote C
- Martínez‐Hurtado E
- Martínez‐Pinedo C
- Martínez‐Pérez P
- Martín‐Arévalo J
- Marx W
- Marzi F
- Marçal A
- Marín H
- Masciandaro A
- Mashat A
- Mashbari Hassan N
- Massey LH
- Massie E
- Massobrio A
- Mastoridis S
- Math S
- Mathew S
- Matić S
- Matos Costa P
- Matute M
- Maté Mate P
- Matías‐García B
- Maw A
- Mazingi Dennis
- Mazzotta E
- Mazzotti F
- McAleer J
- McAree B
- McCanny A
- Mccluney S
- Mccormick P
- McDermott FD
- McElhinney K
- McEwen R
- McGivern K
- McGrath John S
- McIlmunn C
- McIntosh S
- McIntyre J
- McKay Siobhan
- Mckay Siobhan C
- McKevitt K
- McLean Kenneth A
- McNaught C
- McNeill Alan
- McNicol F
- MdRazali. I null
- Mehigan BJ
- Mehraj A
- Meima‐van Praag EM
- Mekhael M
- Melchor‐Ruan J
- Melenhorst J
- Melhem S
- Memon AS
- Memos N
- Mendes F
- Mendes JR
- Mendoza‐Moreno F
- Meneghini S
- Mercado MÁ
- Merdrignac A
- Merh R
- Meriç S
- Messner F
- Metallidis Symeon
- Metwalli M
- Metzger J
- Michalopoulos N
- Michalski C
- Michel M
- Micic D
- Migliore M
- Mignot G
- Miguel T
- Mihanovic J
- Mihmanli M
- Miladinov M
- Milanović M
- Milic LJ
- Mills Emily C
- Mills SJ
- Milne K
- Minaya Bravo AM
- Minaya‐Bravo Ana
- Minaya‐Bravo Ana
- Minaya‐Bravo Ana
- Mingoli A
- Minicozzi A
- Minto G
- Mir I
- Mirabella A
- Miranda P
- Mirica RM
- Mirnezami R
- Mishra N
- Mishra S
- Mishra T
- Misra S
- Mitchell D
- Mitchell S
- Mithany R
- Mitra JK
- Mitrofan C
- Mittal R
- Mittal Rohin
- Miu V
- Mochet S
- Modolo Maria Marta
- Modolo Maria Marta
- Moftah M
- Moggia E
- Mohamed Sidek AS
- Mohammad Z
- Mohammed MM
- MohammedJibreel M
- Mohan H
- Mohan Helen M
- Mohan Helen M
- Mohd Azman ZA
- Mohd Yunus MF
- Mohsine R
- Mongelli F
- Montauban P
- Montelatici M
- Monteleone M
- Montella MT
- Montori G
- Montuori M
- Moore Rachel
- Moorthy M
- Morais H
- Moras L
- Mora‐Guzmán I
- Morelli L
- Moretto G
- Morgan R
- Moritani K
- Moro‐Valdezate D
- Morris A
- Morsi A
- Mosley F
- Moss J
- Moszkowicz David
- Moug S
- Moug Susan
- Moug Susan
- Moura F
- Mourad M
- Mshelbwala P
- Msherghi A
- Mudawi I
- Muduly D
- Muguerza JM
- Muiesan P
- Mukherjee S
- Muller B
- Mulligan CS
- Mungo S
- Muratore A
- Murawa D
- Murgese A
- Murphy C
- Musetti S
- Mustafa A
- Mutter D
- Muzamil J
- Muñoz Camarena JM
- Muñoz‐Atienza V
- Muñoz‐Bellvis L
- Naar L
- Nacif L
- Nafees Ahmed R
- Nageh MA
- Nahm C
- Najarian M
- Nally D
- Namazov İ
- Nankivell Paul
- Narahari Krishna
- Nassa H
- Nassif M
- Natale J
- Naumann D
- Navaratne L
- Nazir S
- Neary P
- Neary PM
- Neely D
- Negoi I
- Negoi Ionut
- Negoita VM
- Nel D
- Nelli T
- Nepogodiev Dmitri
- Nepogodiev Dmitri
- Neri J
- Nespoli LC
- Nessim C
- Neville Iuri
- Newman S
- Newman T
- Newton C
- Newton K
- Ng HJ
- Ng Joe
- Ng S
- Ng V
- Ng V
- Ngo CW
- Ng‐Kamstra Joshua S
- Nicolás‐López T
- Nikaj H
- Nikolaou S
- Nikolic S
- Niquen Milagros
- Nisar P
- Nitschke C
- Nogueira O
- Nogueiro J
- Nogués A
- Noiret B
- Nolan GJ
- Norcini C
- Nordberg M
- Notte F
- Nouh T
- Novello S
- Novikova A
- Nowak K
- Ntirenganya Faustin
- Nugent E
- Nunes Coelho M
- Nunes R
- Nunez‐Garcia B
- Nunoo‐Mensah JW
- Nuñez Del Barrio H
- Nwabuoku SE
- Núñez J
- Obeidat K
- Ocaña J
- Ochagavía S
- Oguttu B
- Okafor B
- Okunlola A
- Olaogun J
- Olasehinde O
- Oldfield F
- Oliva Mompean F
- Oliveira A
- Olivier J
- Olivieri M
- Olivos Maricarmen
- Olori S
- Olson KA
- Olute A
- Omar W
- Omeroglu S
- Ong SL
- Onos L
- Oosterlinck W
- Oosterling S
- Opocher E
- Ortega Vázquez I
- Ortiz de Solórzano Aurusa FJ
- Ortiz López D
- Osagie O
- Oseira A
- Osman N
- Osorio Ramos A
- Otero A
- Otoniel LR
- Oussama Kacimi
- Outani Oumaima
- Ovejero Merino E
- Owen H
- Owens P
- Oyende O
- Ozben V
- Ozcelık MF
- Ozgediz D
- Ozmen BB
- O’Brien H
- O’Brien S
- O’Donnell S
- O’Malley S
- O’Riordan J
- O’Shea M
- P Delrio
- Pacheco Sánchez D
- Padilla‐Valverde D
- Padmore G
- Pagano G
- Pajan H
- Palagi S
- Palma P
- Palmeri M
- Panahi P
- Pandey D
- Paniagua García Señorans M
- Papaconstantinou I
- Papadopoulos V
- Papagni V
- Papatheodorou P
- Paquette N
- Parasyris S
- Pareek P
- Pareja Rene
- Parello A
- Parente A
- Parini S
- Parise P
- Park J
- Parkin E
- Parkins K
- Parlanti D
- Parmar C
- Parra Baños PA
- Parray FQ
- Parreira R
- Parreño‐Sacdalan Marie Dione
- Parreño‐Sacdalan Marie Dione
- Parseliunas A
- Parwaiz I
- Pasini F
- Paspaliari D
- Pata Francesco
- Pata Francesco
- Pata Francesco
- Patel Akshay
- Patel K
- Patel M
- Patel P
- Patil S
- Patrone R
- Patrício B
- Pattyn P
- Pattyn P
- Pavlov M
- Pedrazzani C
- Pedro J
- Pedro V
- Peirce C
- Pejnovic L
- Pejovic I
- Pellegrino L
- Pellino G
- Pellino Gianluca
- Peluso C
- Penumadu P
- Pera R
- Peralta Ferreira M
- Pereca J
- Pereira Rodrigues A
- Pereira A
- Pereira C
- Pereira I
- Pereira R
- Perez Gonzalez M
- Perez D
- Pergolini I
- Perivoliotis K
- Peros G
- Perotto LO
- Perra T
- Perrone G
- Persad A
- Persiani R
- Pertile D
- Peteja M
- Petrillo A
- Peyroteo M
- Pezzuto AP
- Peña Ros E
- Peña Soria MJ
- Pham H
- Phan D
- Phang PT
- Phillips E
- Picardo AL
- Picciariello A
- Picciochi Maria
- Pickett L
- Picón Rodríguez R
- Pieniowski E
- Piessen G
- Pina S
- Pinilla Morales RE
- Pinkney Thomas D
- Pinotti E
- Pinto J
- Pipara A
- Piper Rory J
- Pipitone Federico NS
- Pirozzolo G
- Pirzada A
- Pisani Ceretti A
- Pisanu A
- Pius Ogolekwu I
- Pla‐Marti V
- Pockney P
- Pockney Peter
- Pockney Peter
- Pockney Peter
- Podda M
- Poeze M
- Poggioli G
- Police A
- Polydorou A
- Pol‐Fachin L
- Ponchietti L
- Popoola AA
- Porcu A
- Portinari M
- Posadas‐Trujillo OE
- Posma‐Bouman L
- Potter R
- Pourcher G
- Powell S
- Pozotou I
- Praetorius C
- Pramesh CS
- Prando D
- Presl J
- Price C
- Price Stephen J
- Prieto Calvo M
- Prieto Nieto MI
- Pronk AJM
- Prosperi P
- Provozina A
- Pruvot FR
- Pujari R
- Pujol Cano N
- Pérez Sánchez MA
- Pérez‐Saborido B
- Qadan M
- Qasem A
- Qatora MS
- Quante M
- Quintana Martinic M
- Quiroga‐Valcárcel A
- Qureshi Ahmad
- Qureshi AU
- Raby‐Smith W
- Radenkovic Dejan
- Raggio E
- Rai L
- Rajan S
- Rajaretnam N
- Rakvin I
- Ramachandran A
- Ramalho de Almeida F
- Ramamoorthy R
- Ramasamy S
- Ramcharan S
- Ramesh P
- Ramirez Faraco M
- Ramirez Romero P
- Ramos Bonilla A
- Ramos D
- Ramos‐De la Medina Antonio
- Ramos‐Martín P
- Ramwell A
- Rao S
- Rapaport S
- Rashid A
- Rashid MM
- Rasoaherinomenjanahary F
- Rattizzato S
- Ratto C
- Raval M
- Ravindrakumar S
- Ravindran S
- Rayamajhi S
- Raymond T
- Razafindrahita JB
- Recordare A
- Reddy P
- Redfern J
- Refky B
- Rega D
- Rega D
- Regina de Sampaio L
- Reilly J
- Reim D
- Reinhard T
- Revez T
- Rey Ferro M
- Rey Valcarcel C
- Reynolds IS
- Ribeiro A
- Ribeiro CG
- Ribeiro R
- Ribolla M
- Rice D
- Richards S
- Richards T
- Richards Toby
- Riddell A
- Ridgway PF
- Righini E
- Riley C
- Rimonda R
- Ringressi MN
- Ripollés‐Melchor J
- Riquoir Altamirano C
- Risaliti M
- Riva C
- Rivas R
- Rivera Carlos Jose Perez
- Rivera‐Alonso D
- Rizk M
- Rizzi A
- Roberts Keith
- Roberts Keith
- Robertson Faith
- Robinson A
- Roca Calvo MJ
- Rodrigo VSD
- Rodrigues K
- Rodriguez Artigas JM
- Rodriguez JL
- Rodríguez Gómez L
- Rodwell H
- Rogers LJ
- Rogers M
- Rojo López JA
- Roldón Golet M
- Romano M
- Romero Bañuelos E
- Romero de Diego A
- Ronellenfitsch U
- Rooney SM
- Rosa F
- Rose J
- Roslani AC
- Roslani April C
- Rosseau Gail
- Rossi S
- Roszkowski R
- Rottoli M
- Roux A
- Roxo V
- Roy Mahapatra S
- Royle T
- Rubio‐Perez I
- Ruivo A
- Ruiz Esquide M
- Ruiz Manzanera JJ
- Ruiz Soriano M
- Ruiz‐Escobar A
- Ruiz‐Marín M
- Russ J
- Russo IS
- Rutegård M
- Rutegård Martin
- Rutegård Martin
- Rutherford D
- Ruzgar NM
- Ruzzenente A
- Ryan M
- Ryan ÉJ
- Ryska O
- Río Lafuente FD
- S RRR
- Saad MM
- Saafan T
- Saavedra J
- Sabry A
- Saeed S
- Saez Carlin P
- Sagar J
- Sagnotta A
- Sahid Nik Amin
- Sahin I
- Sahnan K
- Saklani A
- Sakr A
- Saksena AR
- Salazar A
- Saleem A
- Saleem A
- Saleh M
- Salem H
- Salem H
- Salem M
- Salerno G
- Sales Mallafré R
- Salgado‐Nesme N
- Salim A
- Salimoğlu S
- Salindera S
- Sallam I
- Samadov E
- Samih A
- Samir Abdelaal A
- Samison LH
- Samkari A
- Sammarco G
- Sammour T
- Sampaio da Nóvoa Gomes Miguel II
- Sampaio Soares A
- Sampietro GM
- San Miguel C
- Sanchez Cabezudo Noguera F
- Sanchez Gonzalez J
- Sanchez Jimenez R
- Sanchez‐Casado AB
- Sanchez‐Pelaez D
- Sanchon L
- Sancho‐Muriel J
- Sanli AN
- Santanach C
- Santarrufina Martinez S
- Santero‐Ramirez MS
- Santos Bezerra T
- Santos Irène
- Santos PMDD
- Santos R
- Santos‐Sousa H
- Sanz Larrainzar A
- Sanz Ortega G
- Sanz‐López R
- Sapienza P
- Sapre D
- Saraiva P
- Sarantitis I
- Sarigul M
- Sarin A
- Sarjanoja E
- Sarma DR
- Sarpel U
- Sarre C
- Sartarelli L
- Sarveswaran J
- Sasapu K
- Sasia D
- Satoi Sohei
- Satoi Sohei
- Saudí S
- Sauvain M
- Sauvat F
- Saverio Salomone Di
- Saverio Salomone Di
- Savković N
- Sayyed R
- Sayyed Raza
- Scabini S
- Scalabre A
- Scanu AM
- Schache Andrew
- Schache Andrew G
- Schaller Karl
- Scheiwiller A
- Schiavo M
- Schiergens T
- Schineis C
- Schizas D
- Schlesinger N
- Schnitzbauer Andreas A
- Schwartz PB
- Scott L
- Scotton G
- Scrima O
- Sebai A
- Seebah K
- Seeliger B
- Seenivasagam Rajkumar Kottayasamy
- Seguin‐givelet A
- Segura‐Sampedro JJ
- Segura‐Sampedro Juan José
- Sehgal T
- Sehouli Jalid
- Seleim A
- Selmani J
- Semina E
- Sena G
- Senossi O
- Serevina OL
- Serralta de Colsa D
- Serrano González J
- Serrano‐Navidad M
- Sert İ
- Servadei Franco
- Seyi‐Olajide Justina O.
- Seymour Z
- Sganga G
- Sgrò A
- Shah J
- Shah S
- Shah ZA
- Shaikh I
- Shaikh S
- Shakoor Z
- Shanthakunalan K
- Sharabiany S
- Sharma Neil
- Sharma P
- Shaw Catherine A
- Shaw Richard
- Shaw Richard
- Sheel A
- Shehata S
- Shenit K
- Sheridan K
- Sherief M
- Sherif A
- Sherif Ahmed Elshawadfy
- Sherif G
- Shokuhi P
- Sholadoye TT
- Shortland T
- Shream S
- Shrestha A
- Shu Sebastian
- Shylasree TS
- Sian T
- Siaw‐Acheampong Kwabena
- Sibilla MG
- Siddiqui MT
- Sidiropoulos T
- Silva A
- Silva M
- Silva N
- Silva R
- Silveira Nunes I
- Silvestre D
- Simões JFF
- Singh AA
- Singh Jagdeep K
- Singh MP
- Singh R
- Singh S
- Singh S
- Sion M
- Skrovina M
- Smart Neil
- Smart Neil J
- Smith C
- Smith H
- Smith J
- Smith L
- Soh JY
- Sohrabi C
- Sokolov M
- Solari F
- Soldevila Verdeguer C
- Soliman H
- Soltan H
- Soreide Kjetil
- Soriano AI
- Soriero D
- Sorrentino L
- Sorribas Grifell M
- Sosa Duran EE
- Sosa‐Rodríguez MV
- Soto Montesinos C
- Souadka A
- Soulé Martínez CE
- Sousa Fernandes M
- Sousa R
- Sousa S
- Spagni G
- Spampinato MG
- Spanu A
- Spartalis E
- Spencer N
- Spiezio G
- Spinelli A
- Spinelli Antonino
- Spolini A
- Sreedharan L
- Srikumar B
- Sriram RK
- Srishankar S
- Sroczyński P
- St John S
- Stafford J
- Stavrinidou O
- Stebbing J
- Steele C
- Steidle C
- Steinke J
- Stevens K
- Stevenson J
- Stevic D
- Stewart Grant D
- Stewart Grant D
- Stewart KE
- Stockdale T
- Stoica B
- Strate T
- Stylianides N
- Stylianidis G
- Subhi MT
- Subocius A
- Subramaniam S
- Sud A
- Sund Malin
- Sundar Sudha
- Sundar Sudha
- Sundaram Venkatesan G
- Sundhu M
- Suszták N
- Sutherland A
- Swinson B
- Syed WAS
- Syllaios A
- Szatmary P
- Szubota I
- Sánchez del Pueblo C
- Sánchez Fuentes N
- Sánchez Tocino JM
- Sánchez‐García S
- Sánchez‐Guillén L
- Tabiri Stephen
- Tactuk N
- Taddei A
- Tadic B
- Taibi A
- Talaat M
- Talal El‐Abur I
- Talukder S
- Talwar R
- Tamini N
- Tammaro P
- Tan JA
- Tan KHM
- Tan XS
- Tanal M
- Tang AM
- Tanzanu M
- Tartaglia D
- Tasis N
- Tatar OC
- Tavares F
- Tawheed A
- Tayeh S
- Taylor Elliott H
- Tebala GD
- Teh C
- Teixeira J
- Teixeira M
- Tejero‐Pintor FJ
- Telma K
- Testa V
- Tewari N
- Tezas S
- Thaha MA
- Thalgaspitiya SPB
- Thanapal MR
- Thekinkattil Dinesh
- Theodosopoulos T
- Theophilidou E
- Thian A
- Thomas A
- Thompson D
- Thrumurthy S
- Thulasiraman SV
- Timbrell S
- Tirloni L
- Tirotta Fabio
- Titu S
- Tiwari Abhinav
- Tojal A
- Tokocin M
- Tolani MA
- Tom K
- Tonini V
- Tooulias A
- Torres Arcos C
- Torres A
- Townend D
- Townend Philip
- Townend Philip
- Townson A
- Trabulsi N
- Travaglio E
- Trebol J
- Tribillon E
- Troncoso Pereira P
- Tropeano FP
- Trout Isobel M
- Trujillo Díaz J
- Tsai L
- Tsarkov P
- Tsiaoussis I
- Tsirlis T
- Tsoulfas G
- Tsoulfas Georgios
- Tsui G
- Tucci R
- Tufo A
- Tugmen C
- Tulina I
- Tuncer K
- Turina M
- Turk K
- Turnbull A
- Turrado‐Rodriguez V
- Turri G
- Tweedle E
- Tzedakis S
- Tzovaras G
- Tébar Zamora A
- Ugarte‐Sierra B
- Ugolini G
- Ullrich S
- Uludağ SS
- Umair M
- Umar A
- Uras C
- Urbani A
- Urbieta A
- Usai A
- Uslu G
- Usta MA
- Utkan NZ
- Utrilla Fornals A
- Uy Magadia E
- Uyanik MS
- Uzunoglu FG
- Vaccarella G
- Valbuena Jabares V
- Valdes‐Hernandez J
- Vale R
- Valenzuela JI
- Valero Soriano M
- Vallance Abigail
- Valle Rubio A
- Valverde S
- Van de Putte D
- Van den Eynde J
- Van den Eynde R
- van der Plas Willemijn
- Van Heinsbergen M
- Van Nieuwenhove Y
- Van Ramshorst G
- van Ramshorst Gabrielle H
- Vanker R
- Varcada M
- Varghese Chris
- Varma MG
- Vartanoglu T
- Vasconcelos M
- Vasey C
- Vasljević J
- Vassiliu P
- Vaz S
- Vaz‐Pereira R
- Velasquez Cuasquen BG
- Velchuru V
- Velickovic D
- Velidedeoglu M
- Vendrame C
- Venn M
- Venn Mary L
- Venskutonis D
- Vera Mansilla C
- Verberne C
- Vergari R
- Vernon L
- Vervoort D
- Vescio G
- Vezakis A
- Veziant J
- Videira JF
- Vidya Raghavan
- Vidya Raghavan
- Vieira Barros A
- Vieira Caroço T
- Vieira Paiva Lopes AC
- Vieira A
- Vieira B
- Vignali A
- Vignotto C
- Vigorita V
- Vijayan D
- Vilar‐Compte D
- Villalabeitia Ateca I
- Villalonga B
- Vimalachandran D
- Vimalachandran Dale
- Vimalchandran Dale
- Violante T
- Vishnoi JR
- Viswanath Y
- Vitali A
- Vitone L
- Vives RV
- Vo UG
- Volpin E
- Von Papen M
- Vovola F
- Vucic N
- Vázquez Fernández A
- Văcăraș AB
- Wadham B
- Waldron A
- Walker P
- Walkes K
- Walędziak M
- Wani R
- Waqar SH
- Warren O
- Warren Oliver J
- Watson E
- Watson LJ
- Watson N
- Wedderburn Duane
- Weitz J
- Welsch T
- Werner J
- Westwood E
- Whelan M
- Whitmore H
- Wilkin RJW
- Wilkins A
- Wilkins Alex
- Willaert W
- Williams G
- Williams K
- Williams O
- Wilson M
- Wilson M
- Wimmer A
- Winter D
- Winter Stuart C
- Wong MP
- Wood M
- Woods R
- Worku D
- Wright Naomi
- Wullschleger M
- Xavier R
- Xenaki S
- Xynos E
- Y J
- Yadev I
- Yalkın Ö
- Yanar H
- Yang W
- Yanishev A
- Yassin N
- Ye G
- Yepes Cano AF
- Yesantharao P
- Yetkin G
- Yezzaji H
- Yeşilyurt D
- Yiallourou A
- Yigitbas H
- Yildirim A
- Yildiz A
- Yildiz A
- Young R
- Yousof EA
- Youssef M
- Yurttas C
- Yánez C
- Yüksel E
- Zafar SN
- Zakaria AD
- Zakaria Z
- Zakharenko A
- Zambon M
- Zamfir‐Chiru‐Anton M
- Zanus G
- Zegarac M
- Zelić M
- Zengin AK
- Zerbib P
- Zervas K
- Zese M
- Zhang H
- Zizzo M
- Zmora O
- Zografos C
- Zonta S
- Zorrilla Ortúzar J
- Zourntou S
- Zubaidi A
- Ângelo M
- Älgå A
- Çelebi F
- Çolak E
- Öfner D
- Öhlberger L
- Özant A
- Özçay N
- Öğücü H
- Überrück L
- Ćoza I
- Ławnicka A
- Žatecký J
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
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