14,846 research outputs found
Sintagmatiese leksikale betrekkinge in Afrikaans
Sedert die werk van Porzig (1934) word daar aanvaar dat sintagmatiese leksikale betrekkinge Cn tipe betekenisbetrekking wat bestaan tussen twee leksikale items op 'n sin tagmatiese vlak, saos in die geval van hand en blaf) ook verreken moet word in 'n teorie oor leksikaIe struktuur. Hoewel verskeie navorsers in die verlede hierdie onderwerp aangespreek het, het dit nle die aandag gekry wat dit verdien rue, veral rue in die Afrikaanse taalwetenskap rue. In hierdie artikel sal ek sintagmatiese leksikaIe betrekkinge kontrasteer met paradigmatiese leksikaIe .betrekkinge, wys op verskillende tipes sintagmatiese betrekkinge en aantoon watter relevansie hierdie verskynsel vir die leksikografie het
Epigeal fauna of urban food production sites show no obvious relationships with soil characteristics or site area
Urban food production is a growing area of interest as a way of increasing food security, social capital and biodiversity. As food production relies upon ecosystem services provided by invertebrates (e.g. decomposition), it is important to understand the underlying factors affecting their distribution. Here we investigated the influence of soil characteristics and patch area on the abundance and diversity of epigeal invertebrates. Seventeen sites of different size from in and around Leeds, UK, were selected from an open source database on urban food production. Pitfall traps were placed along transects to collect beetles, springtails, and spiders. These invertebrates were identified and counted, adjusting total counts for the number of traps used at each location. Soil samples from the trap locations were homogenized, dried, and analysed to measure organic carbon content, moisture content, and pH, while productivity was assessed by growing radish Raphanus sativus on the soils under uniform conditions. This study found no evidence of correlation of epigeal abundance and diversity with site area or soil characteristics. These findings suggest that there is no evidence as yet of urban food production sites that are too small to be able to draw upon ecosystem services delivered by epigeal invertebrates
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Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats.
Approximately 25% of patients who are prescribed opioids for chronic pain misuse them, and 5 to 10% develop an opioid use disorder. Although the neurobiological target of opioids is well known, the molecular mechanisms that are responsible for the development of addiction-like behaviors in some but not all individuals are poorly known. To address this issue, we used a unique outbred rat population (heterogeneous stock) that better models the behavioral and genetic diversity that is found in humans. We characterized individual differences in addiction-like behaviors using an addiction index that incorporates the key criteria of opioid use disorder: escalated intake, highly motivated responding, and hyperalgesia. Using in vitro electrophysiological recordings in the central nucleus of the amygdala (CeA), we found that rats with high addiction-like behaviors (HA) exhibited a significant increase in γ-aminobutyric acid (GABA) transmission compared with rats with low addiction-like behaviors (LA) and naive rats. The superfusion of CeA slices with nociceptin/orphanin FQ peptide (N/OFQ; 500 nM), an endogenous opioid-like peptide, normalized GABA transmission in HA rats. Intra-CeA levels of N/OFQ were lower in HA rats than in LA rats. Intra-CeA infusions of N/OFQ (1 μg per site) reversed the escalation of oxycodone self-administration in HA rats but not in LA rats. These results demonstrate that the downregulation of N/OFQ levels in the CeA may be responsible for hyper-GABAergic tone in the CeA that is observed in individuals who develop addiction-like behaviors. Based on these results, we hypothesize that small molecules that target the N/OFQ system might be useful for the treatment of opioid use disorder
Psychometric evaluation of the German version of a social support scale of FAFHES (family functioning, family health and social support)
This is the peer reviewed version which has been published in final form at https://doi.org/10.1111/scs.12700. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.BACKGROUND:
Family members often need to be supported in informal care of the elderly and desire to be involved into care planning and decision-making. Valid and reliable instruments are needed to measure how family members perceive the care and support they receive from nurses for older family members living at home.
AIM:
The purpose of this study was to translate the 20-item social support scale of the Family Functioning, Family Health and Social Support (FAFHES) questionnaire from English to German and test the validity and reliability of the scale among Swiss-German-speaking family caregivers of home-dwelling elderly people who receive home healthcare services.
METHODS:
A cross-sectional study was conducted to test the empirical and psychometric properties of the translated and culturally adapted version of the social support questionnaire. A factor analysis with the principal component analysis PCA was used to test construct validity. The internal consistency of items was measured with the Cronbach`s alpha coefficient.
RESULTS:
After a rigorous translation process the original 20-item questionnaire was adapted into a 19-item version and tested with family caregivers (n = 207) of home-dwelling elderly. Psychometric testing of the German version of the social support questionnaire revealed that the three factors - affirmation, affect and concrete aid - were congruent with the original questionnaire. The accounted variance was 79.5% and the internal consistency determined by the Cronbach's alpha was 0.973.
CONCLUSION:
The German version of the social support scale of the FAFHES questionnaire is a valid and reliable instrument to assess family perceived support on three dimensions - affirmation, affect and concrete aid - received from nursing professionals. The questionnaire should be tested further in other German-speaking population
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Profits and Fractal Properties: Notes on Marx, Countertendencies and Simulation Models
© 2017 Informa UK Limited, trading as Taylor & Francis Group. There are new reasons for revisiting Marx’s elaboration on the rate of profit because contemporary debates provide findings from the MEGA Project, long-term data on the rate of profit, and tools for dealing with complexity and non-equilibrium systems. This article proposes that the interplay between the tendency and the countertendencies of the rate of profit to fall can be translated into a simple system of equations, one based on each chapter of Section Three of Capital—as if Marx sought to mathematically formalise his insights. This article reviews previous debates, presents data and runs a simulation model, showing that the rate of profit behaves as fractals.Coordenação de Aperfeiçoamento de Pessoal de NÃvel Superior (CAPES, Brazil), grant (BEX 0840/14-9
The experience of long-term opiate maintenance treatment and reported barriers to recovery: A qualitative systematic review
Background/Aim: To inform understanding of the experience of long-term opiate maintenance and identify barriers to recovery. Methods: A qualitative systematic review. Results: 14 studies in 17 papers, mainly from the USA (65%), met inclusion criteria, involving 1,088 participants. Studies focused on methadone prescribing. Participants reported stability; however, many disliked methadone. Barriers to full recovery were primarily ‘inward focused'. Conclusion: This is the first review of qualitative literature on long-term maintenance, finding that universal service improvements could be made to address reported barriers to recovery, including involving ex-users as positive role models, and increasing access to psychological support. Treatment policies combining harm minimisation and abstinence-orientated approaches may best support individualised recovery
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