Research on the Security of Cold-Chain Logistics

In this paper, the definition of cold-chain logistics and security features are analyzed. Based on overview of China's cold-chain logistics, cold chain, through the status quo at home and abroad contrast, we present some of China's food chain problems. With security control system of thought, and risk management theory, the establishment of a more comprehensive evaluation of cold chain logistics system, through a cold-chain business case analysis, put forward suggestions to solve a few cold-chain logistics security strategy

Capacity Manipulation and Menus of Two Part Tariff Contract in Supply Chain

In a decentralized supply chain, raw material supply uncertainty, phantom orders of downstream firm as well as huge investment sunk costs leads to supplier's production capacity manipulation behavior. A supply chain consisting of a supplier and a retailer who faces a newsvendor problem is considered. The impact of supplier's production capacity manipulation on retailer's purchase decision is discussed. The retailer can adopt a menu of two part tariff contract regarding the terms of trade and capacity. Both supplier and retailer have prior belief about counterpart decision behavior. Then, we construct menus of two part tariff contract offered by the retailer to the supplier who has production capacity manipulation and type dependent reservation profits. Our results show that when capacity difference between type H supplier and type L supplier is higher than a critical threshold, the retailer offers two kinds of optimal menus of two part tariff contract in view of reservation profits difference between the type H supplier and type L supplier, and that both supplier and retailer's prior belief about counterpart decision behavior affect optimal menus of two part tariff contract. Finally, a case study shows our conclusions

Wave-particle Duality and Institutional Arrangement on Division in Supply Chain Cluster

This paper is based on the practice in China, takes the coupling between industrial cluster and supply chain as the new angle using by the modern supply chain theory and industry theory, considering the supply chain cluster as such a organization: "originated but not limited to the enterprise, based on but not localized to the cluster". Based on the physical theory and the wave-particle duality, the supply chain cluster is the special organization whose characteristic has wave-particle duality. There exists sophisticated division of labor between upstream and downstream enterprises in a supply chain cluster, and the cost-benefit computing is the main factor to determine the selection of institutional arrangement on division of labor. By enforcing different vertical relations of supply chain cluster, supply chains and their enterprises can optimize the selection and integration of different institutional arrangement on division of labor. A case study is verified our conclusions

China's Rural Logistics Distribution

Only including agricultural products logistics, agricultural means of production logistics, rural daily consumer goods logistics, as well as rural reverse logistics, it really be considered "rural logistics". This paper analyzes the distribution of agricultural products, and distribution of daily consumer goods, agricultural means of production distribution, rural reverse logistics; states that chain management should be one of its meaning in new rural modern circulation system, and logistics distribution is an effective way to enhance effectiveness of chain, therefore this article attempts to integrate the 4 kinds of logistics to a distribution center. In building a rural distribution network, we should consider the original network, but also should pay attention to the needs of new rural construction

An Analysis and Optimization of the Value Chain of Dairy Industry after the Sanlu Event in China

Sanlu melamine milk event shocked the whole world after the Olympic Games successfully closing in Beijing in August 2008 It was reported more than six thousands babies were affected. It was not Sanlu only, but also YiLi, Mengniu and other firms Their products had also been found to contain melamine. The dairy industry of china was trapped in the crisis of confidence At the same time more foreign brands took the opportunity to occupy the market. Sanlu event has brought the industry to an unprecedented crisis So what's the key point of China's dairy industry? How to be out of trouble and obtain a competitive advantage? We tried to build a model based on the industry value chain to analyze and solve the proble

An Analysis on Types and Business Activities of Farmer Middlemen in Strawberry Production-A Case Study

Among all the types of distributors who play different roles in the vegetables and fruits distribution system, fanner middlemen have attracted increasing attention Farmer middlemen, who hold more than 80% of the market in strawberry distribution in Jiande Strawberry Wholesale Market located in Xutang village, have fitlfilled a very Important function in the distribution process The paper takes farmer middlemen in this village as a case study to clarify their types and highlight their function through systematically analyzing their business activities Farmer middlemen's limitations and development tendency are also analyzed in the en

Transgenerational Effects of Stress Exposure on Offspring Phenotypes in Apomictic Dandelion

Heritable epigenetic modulation of gene expression is a candidate mechanism to explain parental environmental effects on offspring phenotypes, but current evidence for environment-induced epigenetic changes that persist in offspring generations is scarce. In apomictic dandelions, exposure to various stresses was previously shown to heritably alter DNA methylation patterns. In this study we explore whether these induced changes are accompanied by heritable effects on offspring phenotypes. We observed effects of parental jasmonic acid treatment on offspring specific leaf area and on offspring interaction with a generalist herbivore; and of parental nutrient stress on offspring root-shoot biomass ratio, tissue P-content and leaf morphology. Some of the effects appeared to enhance offspring ability to cope with the same stresses that their parents experienced. Effects differed between apomictic genotypes and were not always consistently observed between different experiments, especially in the case of parental nutrient stress. While this context-dependency of the effects remains to be further clarified, the total set of results provides evidence for the existence of transgenerational effects in apomictic dandelions. Zebularine treatment affected the within-generation response to nutrient stress, pointing at a role of DNA methylation in phenotypic plasticity to nutrient environments. This study shows that stress exposure in apomictic dandelions can cause transgenerational phenotypic effects, in addition to previously demonstrated transgenerational DNA methylation effects

Disparities and risks of sexually transmissible infections among men who have sex with men in China: a meta-analysis and data synthesis.

BACKGROUND: Sexually transmitted infections (STIs), including Hepatitis B and C virus, are emerging public health risks in China, especially among men who have sex with men (MSM). This study aims to assess the magnitude and risks of STIs among Chinese MSM. METHODS: Chinese and English peer-reviewed articles were searched in five electronic databases from January 2000 to February 2013. Pooled prevalence estimates for each STI infection were calculated using meta-analysis. Infection risks of STIs in MSM, HIV-positive MSM and male sex workers (MSW) were obtained. This review followed the PRISMA guidelines and was registered in PROSPERO. RESULTS: Eighty-eight articles (11 in English and 77 in Chinese) investigating 35,203 MSM in 28 provinces were included in this review. The prevalence levels of STIs among MSM were 6.3% (95% CI: 3.5-11.0%) for chlamydia, 1.5% (0.7-2.9%) for genital wart, 1.9% (1.3-2.7%) for gonorrhoea, 8.9% (7.8-10.2%) for hepatitis B (HBV), 1.2% (1.0-1.6%) for hepatitis C (HCV), 66.3% (57.4-74.1%) for human papillomavirus (HPV), 10.6% (6.2-17.6%) for herpes simplex virus (HSV-2) and 4.3% (3.2-5.8%) for Ureaplasma urealyticum. HIV-positive MSM have consistently higher odds of all these infections than the broader MSM population. As a subgroup of MSM, MSW were 2.5 (1.4-4.7), 5.7 (2.7-12.3), and 2.2 (1.4-3.7) times more likely to be infected with chlamydia, gonorrhoea and HCV than the broader MSM population, respectively. CONCLUSION: Prevalence levels of STIs among MSW were significantly higher than the broader MSM population. Co-infection of HIV and STIs were prevalent among Chinese MSM. Integration of HIV and STIs healthcare and surveillance systems is essential in providing effective HIV/STIs preventive measures and treatments. TRIAL REGISTRATION: PROSPERO NO: CRD42013003721

VMKDO: Verifiable multi-keyword search over encrypted cloud data for dynamic data-owner

Date online: 15 August 2016</p

Cepred: Predicting the Co-Expression Patterns of the Human Intronic microRNAs with Their Host Genes

Identifying the tissues in which a microRNA is expressed could enhance the understanding of the functions, the biological processes, and the diseases associated with that microRNA. However, the mechanisms of microRNA biogenesis and expression remain largely unclear and the identification of the tissues in which a microRNA is expressed is limited. Here, we present a machine learning based approach to predict whether an intronic microRNA show high co-expression with its host gene, by doing so, we could infer the tissues in which a microRNA is high expressed through the expression profile of its host gene. Our approach is able to achieve an accuracy of 79% in the leave-one-out cross validation and 95% on an independent testing dataset. We further estimated our method through comparing the predicted tissue specific microRNAs and the tissue specific microRNAs identified by biological experiments. This study presented a valuable tool to predict the co-expression patterns between human intronic microRNAs and their host genes, which would also help to understand the microRNA expression and regulation mechanisms. Finally, this framework can be easily extended to other species