331 research outputs found
Development of outcome measures for autoimmune dermatoses
- Author
- A Parodi
- AJ Singer
- AW Lucky
- AY Finlay
- AY Finlay
- B Hahn
- B Kunz
- B Ramsay
- B Tebbe
- C Bombaridier
- C Charman
- C Sitaru
- CH Cook
- CR Charman
- DD Gladman
- Elizabeth Gaines
- HC Williams
- J Albrecht
- J Albrecht
- LF Mentink
- LG Rider
- LG Rider
- M Pfutze
- MB Urowitz
- MD Njoo
- RD Quain
- RD Sontheimer
- RD Sontheimer
- S Beissert
- S Tiling-Grosse
- SR Feldman
- U Mrowietz
- Victoria P. Werth
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2007
- Field of study
Validated outcome measures are essential in monitoring disease severity. Specifically in dermatology, which relies heavily on the clinical evaluation of the patient and not on laboratory values and radiographic tests, outcome measures help standardize patient care. Validated cutaneous scoring systems, much like standardized laboratory values, facilitate disease management and follow therapeutic response. Several cutaneous autoimmune dermatoses, specifically cutaneous lupus erythematosus (CLE), dermatomyositis (DM), and pemphigus vulgaris (PV), lack such outcome measures. As a result, evaluation of disease severity and patients’ response to therapy over time is less reliable. Ultimately, patient care is compromised. These diseases, which are often chronic and relapsing and remitting, are also often refractory to treatment. Without outcome measures, new therapies cannot be systematically assessed in these diseases. Clinical trials that are completed without standardized outcome measures produce less reliable results. Therefore, the development of validated outcome measures in these autoimmune dermatoses is critical. However, the process of developing these tools is as important, if not more so, than their availability. This review examines the steps that should be considered when developing outcome measures, while further examining their importance in clinical practice and trials. Finally, this review more closely looks at CLE, DM, and PV and addresses the recent and ongoing progress that has been made in the development of their outcome measures
Non-classical forms of pemphigus: pemphigus herpetiformis, IgA pemphigus, paraneoplastic pemphigus and IgG/IgA pemphigus
- Author
- Adriana Maria Porro
- Amagai M
- Amagai M
- Amagai M
- Amagai M
- Amagai M
- Anhalt GJ
- Anhalt GJ
- Arranz D
- Asahina A
- Barrance VP
- Beutner EH
- Borradori L
- Bruckner AL
- Bull RH
- Buxton RS
- Camisa C
- Chan LS
- Chan LS
- Chorzelski TP
- Chorzelski TP
- Cozzani E
- Cunha PR
- Czernik A
- DeMento FJ
- Duarte IB
- Durham A
- Düker I
- Emmerson RW
- Fang Y
- Feng SY
- Fernandes IC
- Floden CH
- Fullerton SH
- Gengoux P
- Gooptu C
- Gruss C
- Hashimoto T
- Hashimoto T
- Hashimoto T
- Hashimoto T
- Hashimoto T
- Hashimoto T
- Hashimoto T
- Heng A
- Hertl M
- Hodak E
- Horn TD
- Hosoda S
- Howell SM
- Huff JC
- Huhn KM
- Iida K
- Ingber A
- Inui S
- Ishii K
- Ishii N
- Jablonska S
- Kaplan I
- Kimyai-Asadi A
- Kitajima Y
- Kopp T
- Kowalewski C
- Kozlowska A
- Kubo A
- Kubota Y
- Laura de Sena Nogueira Maehara
- Lebeau S
- Leger S
- Leithauser LA
- Liu Q
- Livia de Vasconcelos Nasser Caetano
- Lu Y
- Lutz ME
- Maciejowska E
- Maldonado F
- Marinovic B
- Martel P
- Maruyama H
- Marzano AV
- Mentink LF
- Micali G
- Miida H
- Milvia Maria dos Santos Enokihara
- Mimouni D
- Mimouni D
- Miura T
- Miyagawa S
- Miyagawa S
- Morita E
- Morizane S
- Moutran R
- Müller R
- Nakajima K
- Nakashima H
- Nguyen VT
- Nishikawa T
- Nousari HC
- Nousari HC
- O'Toole EA
- Ohata C
- Ohyama B
- Oiso N
- Palleschi GM
- Patrício P
- Prado R
- Qian SX
- Robinson ND
- Ruiz-Genao DP
- Sanchez-Palacios C
- Santi CG
- Santiago-et-Sánchez-Mateos D
- Schepens I
- Seah PP
- Sklavounou A
- Sneddon I
- Sneddon IB
- Szturz P
- Tagami H
- Taintor AR
- Tajima M
- Tateishi C
- Tsuruta D
- Verdier-Sevrain S
- Wakahara M
- Wallach D
- Wallach D
- Wang J
- Wang J
- Weston WL
- Yasuda H
- Zaraa I
- Zaraa I
- Zhu X
- Zimmermann J
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2014
- Field of study
The pemphigus group comprises the autoimmune intraepidermal blistering diseases classically divided into two major types: pemphigus vulgaris and pemphigus foliaceous. Pemphigus herpetiformis, IgA pemphigus, paraneoplastic pemphigus and IgG/IgA pemphigus are rarer forms that present some clinical, histological and immunopathological characteristics that are different from the classical types. These are reviewed in this article. Future research may help definitively to locate the position of these forms in the pemphigus group, especially with regard to pemphigus herpetiformis and the IgG/ IgA pemphigus.Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Dermatology DepartmentUniversidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Dermatology and Pathology DepartmentsUNIFESP, EPM, Dermatology DepartmentUNIFESP, EPM, Dermatology and Pathology DepartmentsSciEL
Pemphigus autoimmunity: Hypotheses and realities
- Author
- Abasq C
- Ablin RJ
- Abreu Velez AM
- Acosta E
- Ahmed AR
- Ahmed AR
- Ahmed AR
- Ahmed AR
- Akaike A
- Akman A
- Aksu D
- Alexandroff AB
- Alpsoy E
- Amagai M
- Amagai M
- Amagai M
- Amagai M
- Amagai M
- Amagai M
- Amagai M
- Amagai M
- Amar LS
- Ameglio F
- Angelini G
- Aoki-Ota M
- Aoki-Ota M
- Aoyama Y
- Arakawa M
- Arin MJ
- Armin A
- Arredondo J
- Arredondo J
- Arteaga LA
- Ayatollahi M
- Balda BR
- Barlow Y
- Baroni A
- Baroni A
- Bastian BC
- Bedane C
- Behrens J
- Bektas M
- Bektas M
- Belloni-Fortina A
- Berkowitz P
- Berookhim B
- Beutner E
- Beutner EH
- Bhol K
- Bhol KC
- Billet SE
- Blondin DA
- Boyer B
- Brandsen R
- Brenner S
- Brickman CM
- Bystryn J-C
- Calautti E
- Calvanico NJ
- Calvanico NJ
- Carson PJ
- Cheng H
- Chernyavsky AI
- Chernyavsky AI
- Chernyavsky AI
- Chryssomallis F
- Cirillo N
- Cirillo N
- Cirillo N
- Costantino CM
- Cotterill JA
- Cozzani E
- Craft J
- Cunha PR
- Cunha PR
- Czernik A
- D'Alessandro M
- D'Auria L
- Davies L
- de Bruin A
- DeKruyff RH
- Delva E
- Diaz LA
- Diaz LA
- Diaz LA
- Dick SE
- Diercks GF
- Dmochowski M
- Dobrev H
- Dumas V
- Echigo T
- Empinotti JC
- Enk AH
- Evangelista F
- Eyre RW
- Fiebiger E
- Fine JD
- Frusic-Zlotkin M
- Frusic-Zlotkin M
- Gallo R
- Gebhard KL
- Gera JF
- Gilbert D
- Gniadecki R
- Gorshtein A
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Grando SA
- Green KJ
- Haim S
- Hashimoto K
- Hashimoto K
- Hausermann P
- Hertl M
- Hertl M
- Hertl M
- Hilario-Vargas J
- Holm TL
- Holubar K
- Hotti A
- Howell SM
- Hu CH
- Hu P
- Humbert P
- Ihrie RA
- Ihrie RA
- Iraji F
- Iraji F
- Iwatsuki K
- Jacobi A
- Jeffes EW
- Jennings JM
- Jinbu Y
- Joly P
- Kaithamana S
- Kalantari M
- Kalantari-Dehaghi M
- Kalantari-Dehaghi M
- Kaplan RP
- Karpati S
- Kawasaki Y
- Kebabian JW
- Keskin DB
- Khandpur S
- Kim SC
- Kippenberger S
- Kiss M
- Kitajima Y
- Kljuic A
- Knobler RM
- Koeppen A
- Kolenko P
- Krain LS
- Kricheli D
- Kurzen H
- Kurzen H
- Kwon EJ
- Lambert J
- Lambert LL
- Lanza A
- Lanza A
- Lanza A
- Lee HE
- Lever WF
- Lever WF
- Lever WF
- Lever WF
- Lilien J
- Lin MH
- Lin MS
- Lindstrom J
- Liu L
- Lopez-Robles E
- Lotti R
- Lyubimov H
- Mainali ES
- Mao X
- Marchenko S
- Mashkilleyson NA
- McDonough AK
- Mehta JN
- Mejri K
- Mentink LF
- Milner Y
- Miyagawa S
- Miyagawa S
- Miyamoto H
- Miyaura H
- Moller NP
- Moller NP
- Moon HS
- Morath C
- Morimoto N
- Mueller H
- Muller EJ
- Muller R
- Muller S
- Murahata RI
- Nagel A
- Nait K
- Nguyen VT
- Nguyen VT
- Nguyen VT
- Nguyen VT
- Nguyen VT
- Nguyen VT
- Nguyen VT
- Nguyen VT
- Niizeki H
- Niizeki H
- Nishimura H
- Nousari HC
- Ohata Y
- Ohyama M
- Orlov MD
- Ortega Loayza AG
- Pacheco-Tovar MG
- Pardo J
- Patel M
- Payne AS
- Penneys NS
- Peterson LL
- Piamphongsant T
- Pitoia F
- Potter MD
- Qian J
- Renkl A
- Rickman L
- Rico MJ
- Riechers R
- Risser J
- Romanenko AV
- Rosenberg FR
- Roujeau JC
- Rubenstein DS
- Ruocco V
- Saha M
- Salopek TG
- Sams WM
- Sanchez-Carpintero I
- Satyam A
- Sawai T
- Saxon A
- Schmidt E
- Schultz HY
- Schumann H
- Sebaratnam DF
- Sehgal SN
- Sergei A. Grando
- Serres M
- Sharma P
- Sharma VK
- Shetty A
- Shlomchik MJ
- Shu SY
- Simpson A
- Spindler V
- Stanley JR
- Stanley JR
- Stoytcheva M
- Sugiyama H
- Sullivan TP
- Swanson DL
- Takahashi H
- Talbott JH
- Taylor P
- Thorn GW
- Thornton AM
- Torzecka JD
- Torzecka JD
- Tron F
- Tsunoda K
- Udey MC
- Valikhani M
- Veldman C
- Volberg T
- Wang DW
- Wang X
- Warren SJ
- Wilgram GF
- Williamson L
- Wolff K
- Yamaguchi T
- Yin T
- Yoshimura T
- Younus J
- Zagorodniuk I
- Publication venue
- Informa Healthcare
- Publication date
- 01/02/2012
- Field of study
The goal of contemporary research in pemphigus vulgaris and pemphigus foliaceus is to achieve and maintain clinical remission without corticosteroids. Recent advances of knowledge on pemphigus autoimmunity scrutinize old dogmas, resolve controversies, and open novel perspectives for treatment. Elucidation of intimate mechanisms of keratinocyte detachment and death in pemphigus has challenged the monopathogenic explanation of disease immunopathology. Over 50 organ-specific and non-organ-specific antigens can be targeted by pemphigus autoimmunity, including desmosomal cadherins and other adhesion molecules, PERP cholinergic and other cell membrane (CM) receptors, and mitochondrial proteins. The initial insult is sustained by the autoantibodies to the cell membrane receptor antigens triggering the intracellular signaling by Src, epidermal growth factor receptor kinase, protein kinases A and C, phospholipase C, mTOR, p38 MAPK, JNK, other tyrosine kinases, and calmodulin that cause basal cell shrinkage and ripping desmosomes off the CM. Autoantibodies synergize with effectors of apoptotic and oncotic pathways, serine proteases, and inflammatory cytokines to overcome the natural resistance and activate the cell death program in keratinocytes. The process of keratinocyte shrinkage/detachment and death via apoptosis/oncosis has been termed apoptolysis to emphasize that it is triggered by the same signal effectors and mediated by the same cell death enzymes. The natural course of pemphigus has improved due to a substantial progress in developing of the steroid-sparing therapies combining the immunosuppressive and direct anti-acantholytic effects. Further elucidation of the molecular mechanisms mediating immune dysregulation and apoptolysis in pemphigus should improve our understanding of disease pathogenesis and facilitate development of steroid-free treatment of patients
Measurement and interpretation of same-sign W boson pair production in association with two jets in pp collisions at s = 13 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abeling K
- Abicht NJ
- Abidi SH
- Aboulhorma A
- Abramowicz H
- Abreu H
- Abulaiti Y
- Abusleme Hoffman AC
- Acharya BS
- Adam Bourdarios C
- Adamczyk L
- Adamek L
- Addepalli SV
- Addison MJ
- Adelman J
- Adiguzel A
- Adye T
- Affolder AA
- Afik Y
- Agaras MN
- Agarwala J
- Aggarwal A
- Agheorghiesei C
- Ahmad A
- Ahmadov F
- Ahmed WS
- Ahuja S
- Ai X
- Aielli G
- Aikot A
- Ait Tamlihat M
- Aitbenchikh B
- Aizenberg I
- Akbiyik M
- Akimov AV
- Akiyama D
- Akolkar NN
- Al Khoury K
- Alberghi GL
- Albert J
- Albicocco P
- Albouy GL
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi F
- Algren M
- Alhroob M
- Ali B
- Ali HMJ
- Ali S
- Alibocus SW
- Aliev M
- Alimonti G
- Alkakhi W
- Allaire C
- Allbrooke BMM
- Allen JF
- Allendes Flores CA
- Allport PP
- Aloisio A
- Alonso F
- Alpigiani C
- Alvarez Estevez M
- Alvarez Fernandez A
- Alves Cardoso M
- Alviggi MG
- Aly M
- Amaral Coutinho Y
- Ambler A
- Amelung C
- Amerl M
- Ames CG
- Amidei D
- Amor Dos Santos SP
- Amos KR
- Ananiev V
- Anastopoulos C
- Andeen T
- Anders JK
- Andrean SY
- Andreazza A
- Angelidakis S
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antipov E
- Antonelli M
- Anulli F
- Aoki M
- Aoki T
- Aparisi Pozo JA
- Aparo MA
- Aperio Bella L
- Appelt C
- Apyan A
- Aranzabal N
- Arcangeletti C
- Arce ATH
- Arena E
- Arguin J-F
- Argyropoulos S
- Arling J-H
- Arnaez O
- Arnold H
- Artoni G
- Asada H
- Asai K
- Asai S
- Asbah NA
- Assamagan K
- Astalos R
- Atashi S
- Atkin RJ
- Atkinson M
- Atmani H
- Atmasiddha PA
- Augsten K
- Auricchio S
- Auriol AD
- Austrup VA
- Avolio G
- Axiotis K
- Azuelos G
- Babal D
- Bachacou H
- Bachas K
- Bachiu A
- Backman F
- Badea A
- Bagnaia P
- Bahmani M
- Bailey AJ
- Bailey VR
- Baines JT
- Baines L
- Bakalis C
- Baker OK
- Bakos E
- Bakshi Gupta D
- Balakrishnan V
- Balasubramanian R
- Baldin EM
- Balek P
- Ballabene E
- Balli F
- Baltes LM
- Balunas WK
- Balz J
- Banas E
- Bandieramonte M
- Bandyopadhyay A
- Bansal S
- Barak L
- Barakat M
- Barberio EL
- Barberis D
- Barbero M
- Barel MZ
- Barends KN
- Barillari T
- Barisits M-S
- Barklow T
- Baron Moreno DA
- Baron P
- Baroncelli A
- Barone G
- Barr AJ
- Barr JD
- Barranco Navarro L
- Barreiro Guimarães da Costa J
- Barreiro F
- Barron U
- Barros Teixeira MG
- Barsov S
- Bartels F
- Bartoldus R
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- Basson CR
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- Beauchemin PH
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- Beck HP
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- Beddall AJ
- Bednyakov VA
- Bee CP
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- Biglietti M
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- Camerlingo MT
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- Castillo Gimenez V
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- Castro NF
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- Catmore JR
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- Cekmecelioglu YC
- Celebi E
- Celli F
- Centonze MS
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- Cerny K
- Cerqueira AS
- Cerri A
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- Cervelli A
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- Chargeishvili B
- Charlton DG
- Charman TP
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- Chekulaev SV
- Chelkov GA
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- Cheremushkina E
- Cherepanova E
- Cherkaoui El Moursli R
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- Cheung K
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- Chisholm AS
- Chitan A
- Chitishvili M
- Chizhov MV
- Choi K
- Chomont AR
- Chou Y
- Chow EYS
- Chowdhury T
- Chu KL
- Chu MC
- Chu X
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- Chwastowski JJ
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- Ciocio A
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- Ciungu BM
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- Clavijo Columbie JM
- Clawson SE
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- Clercx J
- Coadou Y
- Cobal M
- Coccaro A
- Coelho Barrue RF
- Coelho Lopes De Sa R
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- Coimbra AEC
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- Connelly IA
- Conroy EI
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- Cooke HG
- Cooper-Sarkar AM
- Cordeiro Oudot Choi A
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- Cortes-Gonzalez A
- Costa MJ
- Costanza F
- Costanzo D
- Cote BM
- Cowan G
- Cranmer K
- Cremonini D
- Crescioli F
- Cristinziani M
- Cristoforetti M
- Croft V
- Crosby JE
- Crosetti G
- Crépé-Renaudin S
- Cueto A
- Cuhadar Donszelmann T
- Cui H
- Cui Z
- Cunningham WR
- Curcio F
- Czodrowski P
- Czurylo MM
- Da Cunha Sargedas De Sousa MJ
- Da Fonseca Pinto JV
- Da Via C
- Dabrowski W
- Dado T
- Dahbi S
- Dai T
- Dal Santo D
- Dallapiccola C
- Dam M
- Damp J
- Dandoy JR
- Daneri MF
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- Dao V
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- Das SJ
- David C
- Davidek T
- Davis-Purcell B
- Dawson I
- Day-hall HA
- De Asmundis R
- De Biase N
- De Castro S
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- Zhemchugov A
- Zheng J
- Zheng K
- Zheng X
- Zheng Z
- Zhong D
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- Zhulanov V
- Zimine NI
- Zinsser J
- Ziolkowski M
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- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 01/04/2024
- Field of study
This paper presents the measurement of fducial and diferential cross sections for both the inclusive and electroweak production of a same-sign W-boson pair in association with two jets (W±W±jj) using 139 fb−1 of proton-proton collision data recorded at a centre-of-mass energy of √s = 13 TeV by the ATLAS detector at the Large Hadron Collider. The analysis is performed by selecting two same-charge leptons, electron or muon, and at least two jets with large invariant mass and a large rapidity diference. The measured fducial cross sections for electroweak and inclusive W±W±jj production are 2.92 ± 0.22 (stat.) ± 0.19 (syst.)fb and 3.38±0.22 (stat.)±0.19 (syst.)fb, respectively, in agreement with Standard Model predictions. The measurements are used to constrain anomalous quartic gauge couplings by extracting 95% confdence level intervals on dimension-8 operators. A search for doubly charged Higgs bosons H±± that are produced in vector-boson fusion processes and decay into a same-sign W boson pair is performed. The largest deviation from the Standard Model occurs for an H±± mass near 450 GeV, with a global signifcance of 2.5 standard deviations
Combination of searches for heavy spin-1 resonances using 139 fb−1 of proton-proton collision data at s = 13 TeV with the ATLAS detector
- Author
- Aad G
- Aakvaag E
- Abbott B
- Abeling K
- Abicht NJ
- Abidi SH
- Aboelela M
- Aboulhorma A
- Abramowicz H
- Abreu H
- Abulaiti Y
- Acharya BS
- Ackermann A
- Adam Bourdarios C
- Adamczyk L
- Addepalli SV
- Addison MJ
- Adelman J
- Adiguzel A
- Adye T
- Affolder AA
- Afik Y
- Agaras MN
- Agarwala J
- Aggarwal A
- Agheorghiesei C
- Ahmad A
- Ahmadov F
- Ahmed WS
- Ahuja S
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- Zhemchugov A
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- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 19/04/2024
- Field of study
A combination of searches for new heavy spin-1 resonances decaying into different pairings of W, Z, or Higgs bosons, as well as directly into leptons or quarks, is presented. The data sample used corresponds to 139 fb−1 of proton-proton collisions at
= 13 TeV collected during 2015–2018 with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting quark pairs (qq, bb,
, and tb) or third-generation leptons (τν and ττ) are included in this kind of combination for the first time. A simplified model predicting a spin-1 heavy vector-boson triplet is used. Cross-section limits are set at the 95% confidence level and are compared with predictions for the benchmark model. These limits are also expressed in terms of constraints on couplings of the heavy vector-boson triplet to quarks, leptons, and the Higgs boson. The complementarity of the various analyses increases the sensitivity to new physics, and the resulting constraints are stronger than those from any individual analysis considered. The data exclude a heavy vector-boson triplet with mass below 5.8 TeV in a weakly coupled scenario, below 4.4 TeV in a strongly coupled scenario, and up to 1.5 TeV in the case of production via vector-boson fusion
Measurement of the tt¯tt¯ production cross section in pp collisions at √s=13 TeV with the ATLAS detector
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- Zakareishvili T
- Zakharchuk N
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- Zanzi D
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- Zeißner SV
- Zemaityte G
- Zeng JC
- Zenin O
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- Zerradi S
- Zerwas D
- Zgubič M
- Zhang B
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- Zhang G
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- Zhao P
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
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- Zhou H
- Zhou N
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- Zhu C
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Ziolkowski M
- Zoccoli A
- Zoch K
- Zorbas TG
- Zormpa O
- Zou W
- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 16/11/2021
- Field of study
A measurement of four-top-quark production using proton-proton collision data at a centre-of-mass energy of 13 TeV collected by the ATLAS detector at the Large Hadron Collider corresponding to an integrated luminosity of 139 fb−1 is presented. Events are selected if they contain a single lepton (electron or muon) or an opposite-sign lepton pair, in association with multiple jets. The events are categorised according to the number of jets and how likely these are to contain b-hadrons. A multivariate technique is then used to discriminate between signal and background events. The measured four-top-quark production cross section is found to be 26+17−15 fb, with a corresponding observed (expected) significance of 1.9 (1.0) standard deviations over the background-only hypothesis. The result is combined with the previous measurement performed by the ATLAS Collaboration in the multilepton final state. The combined four-top-quark production cross section is measured to be 24+7−6 fb, with a corresponding observed (expected) signal significance of 4.7 (2.6) standard deviations over the background-only predictions. It is consistent within 2.0 standard deviations with the Standard Model expectation of 12.0 ± 2.4 fb
Measurement of the energy asymmetry in t(t)over-barj production at 13 TeV with the ATLAS experiment and interpretation in the SMEFT framework
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- Aad G
- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- Aboulhorma A
- Abramowicz H
- Abreu H
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- Abulaiti Y
- Abusleme Hoffman AC
- Acharya BS
- Achkar B
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- Adamek L
- Addepalli S
- Adelman J
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- Affolder AA
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- Agaras MN
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- Zhemchugov A
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- Zhong D
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- Publication venue
- 'Springer Fachmedien Wiesbaden GmbH'
- Publication date
- 28/04/2022
- Field of study
A measurement of the energy asymmetry in jet-associated top-quark pair production is presented using 139fb−1
139
fb
-
1
of data collected by the ATLAS detector at the Large Hadron Collider during pp collisions at s=13TeV
s
=
13
TeV
. The observable measures the different probability of top and antitop quarks to have the higher energy as a function of the jet scattering angle with respect to the beam axis. The energy asymmetry is measured in the semileptonic ttˉ
t
t
¯
decay channel, and the hadronically decaying top quark must have transverse momentum above 350GeV
350
GeV
. The results are corrected for detector effects to particle level in three bins of the scattering angle of the associated jet. The measurement agrees with the SM prediction at next-to-leading-order accuracy in quantum chromodynamics in all three bins. In the bin with the largest expected asymmetry, where the jet is emitted perpendicular to the beam, the energy asymmetry is measured to be −0.043±0.020
-
0.043
±
0.020
, in agreement with the SM prediction of −0.037±0.003
-
0.037
±
0.003
. Interpreting this result in the framework of the Standard Model effective field theory (SMEFT), it is shown that the energy asymmetry is sensitive to the top-quark chirality in four-quark operators and is therefore a valuable new observable in global SMEFT fits
Determination of the parton distribution functions of the proton using diverse ATLAS data from pp collisions at √s = 7, 8 and 13 TeV
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- Zhemchugov A
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- Zimine NI
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- Zinsser J
- Ziolkowski M
- Zoccoli A
- Zoch K
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- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
This paper presents an analysis at next-to-next-to-leading order in the theory of quantum chromodynamics for the determination of a new set of proton parton distribution functions using diverse measurements in pp collisions at \sqrt{s} = 7, 8 and 13 TeV, performed by the ATLAS experiment at the Large Hadron Collider, together with deep inelastic scattering data from ep collisions at the HERA collider. The ATLAS data sets considered are differential cross-section measurements of inclusive W^{±} and Z/gamma^{*} boson production, W^{±} and Z boson production in association with jets, t\bar{t} production, inclusive jet production and direct photon production. In the analysis, particular attention is paid to the correlation of systematic uncertainties within and between the various ATLAS data sets and to the impact of model, theoretical and parameterisation uncertainties. The resulting set of parton distribution functions is called ATLASpdf21
Modelling and computational improvements to the simulation of single vector-boson plus jet processes for the ATLAS experiment
- Author
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- Abbott B
- Abbott DC
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- Abhayasinghe DK
- Abidi SH
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- Zacharis G
- Zaid E
- Zaitsev AM
- Zakareishvili T
- Zakharchuk N
- Zambito S
- Zanzi D
- Zaplatilek O
- Zeissner SV
- Zeitnitz C
- Zeng JC
- Zenin O
- Zenis T
- Zenz S
- Zerradi S
- Zerwas D
- Zhang B
- Zhang DF
- Zhang G
- Zhang J
- Zhang K
- Zhang L
- Zhang M
- Zhang R
- Zhang S
- Zhang X
- Zhang X
- Zhang Z
- Zhao H
- Zhao P
- Zhao T
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou H
- Zhou N
- Zhou Y
- Zhu C
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinsser J
- Ziolkowski M
- Zivkovic L
- Zoccoli A
- Zoch K
- Zorbas TG
- Zormpa O
- Zou W
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
This paper presents updated Monte Carlo configurations used to model the production of single electroweak vector bosons (W, Z/gamma*) in association with jets in proton-proton collisions for the ATLAS experiment at the Large Hadron Collider. Improvements pertaining to the electroweak input scheme, parton-shower splitting kernels and scale-setting scheme are shown for multi-jet merged configurations accurate to next-to-leading order in the strong and electroweak couplings. The computational resources required for these set-ups are assessed, and approximations are introduced resulting in a factor three reduction of the per-event CPU time without affecting the physics modelling performance. Continuous statistical enhancement techniques are introduced by ATLAS in order to populate low cross-section regions of phase space and are shown to match or exceed the generated effective luminosity. This, together with the lower per-event CPU time, results in a 50% reduction in the required computing resources compared to a legacy set-up previously used by the ATLAS collaboration. The set-ups described in this paper will be used for future ATLAS analyses and lay the foundation for the next generation of Monte Carlo predictions for single vector-boson plus jets production
Corrigendum to "Search for flavour-changing neutral-current couplings between the top quark and the photon with the ATLAS detector at √s=13 TeV" (Physics Letters B, 842 (2023), 137379)
- Author
- Aad G
- Abbott B
- Abbott Dc
- Abed Abud A
- Abeling K
- Abidi Sh
- Aboulhorma A
- Abramowicz H
- Abreu H
- Abulaiti Y
- Abusleme Hoffman Ac
- Acharya Bs
- Achkar B
- Adam Bourdarios C
- Adam L
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- Adamek L
- Addepalli Sv
- Adelman J
- Adiguzel A
- Adorni S
- Adye T
- Affolder Aa
- Afik Y
- Agaras Mn
- Agarwala J
- Aggarwal A
- Agheorghiesei C
- Aguilar-Saavedra Ja
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- Alberghi Gl
- Albert J
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- Budagov Ia
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- Burgard Cd
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- Burghgrave B
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- Burzynski Jc
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- Bussey Pj
- Butler Jm
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- Butterworth Jm
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- Büscher V
- Cabras G
- Cabrera Urbán S
- Caforio D
- Cai H
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- Cairo Vmm
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- Calafiura P
- Calderini G
- Calfayan P
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- Calvet D
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- Camacho Toro R
- Camarda S
- Camarero Munoz D
- Camarri P
- Camerlingo Mt
- Cameron D
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- Campanelli M
- Camplani A
- Canale V
- Canesse A
- Cano Bret M
- Cantero J
- Cao Y
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- Capua M
- Carbone A
- Cardarelli R
- Cardenas Jcj
- Cardillo F
- Carli T
- Carlino G
- Carlson Bt
- Carlson Em
- Carminati L
- Carnesale M
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- Carrá S
- Carter Jws
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- Casado Mp
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- Castiglia Eg
- Castillo Garcia L
- Castillo Gimenez V
- Castillo Fl
- Castro Nf
- Catinaccio A
- Catmore Jr
- Cavaliere V
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- Cavasinni V
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- Cerny K
- Cerqueira As
- Cerri A
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- Chakraborty D
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- Chargeishvili B
- Charlton Dg
- Charman Tp
- Chatterjee M
- Chekanov S
- Chekulaev Sv
- Chelkov Ga
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- Chen Sj
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- Cheplakov A
- Cheremushkina E
- Cherepanova E
- Cherkaoui El Moursli R
- Cheu E
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- Chisholm As
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- Chiu Yh
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- Chu Kl
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- Cranmer K
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- Crépé-Renaudin S
- Cristinziani M
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- Croft V
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- Czurylo Mm
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- D'Amico V
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- D'Onofrio A
- D'Onofrio M
- D'Uffizi M
- Da Cunha Sargedas De Sousa Mj
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- Shope Dr
- Shrestha S
- Shrif Em
- Shroff Mj
- Sicho P
- Sickles Am
- Sideras Haddad E
- Sidiropoulou O
- Sidoti A
- Siegert F
- Sijacki D
- Sikora R
- Sili F
- Silva Oliveira Mv
- Silva Jm
- Silverstein Sb
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- Simoniello R
- Simpson El
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- Simsek S
- Sindhu S
- Sinervo P
- Sinetckii V
- Singh S
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- Sioli M
- Siral I
- Sivoklokov Sy
- Sjölin J
- Skaf A
- Skorda E
- Skubic P
- Slawinska M
- Smakhtin V
- Smart Bh
- Smiesko J
- Smirnov Sy
- Smirnov Y
- Smirnova Ln
- Smirnova O
- Smith Ea
- Smith Ha
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- Smith R
- Smizanska M
- Smolek K
- Smykiewicz A
- Snesarev Aa
- Snoek Hl
- Snyder S
- Sobie R
- Soffer A
- Solans Sanchez Ca
- Soldatov Ey
- Soldevila U
- Solodkov Aa
- Solomon S
- Soloshenko A
- Solovieva K
- Solovyanov Ov
- Solovyev V
- Sommer P
- Sonay A
- Song Wy
- Sopczak A
- Sopio Al
- Sopkova F
- Sothilingam V
- Sottocornola S
- Soualah R
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- South D
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- Spalla M
- Spanò F
- Sperlich D
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- Spiteri Dp
- Spousta M
- Staats Ej
- Stabile A
- Stamen R
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- Stampekis A
- Standke M
- Stanecka E
- Stanislaus B
- Stanitzki Mm
- Stankaityte M
- Stapf B
- Starchenko Ea
- Stark Gh
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- Staroba P
- Starovoitov P
- Staszewski R
- Stavropoulos G
- Stärz S
- Steentoft J
- Steinberg P
- Steinhebel Al
- Stelzer B
- Stelzer Hj
- Stelzer-Chilton O
- Stenzel H
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- Stewart Ga
- Stockton Mc
- Stoicea G
- Stolarski M
- Stonjek S
- Straessner A
- Strandberg J
- Strandberg S
- Strauss M
- Strebler T
- Strizenec P
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- Stroynowski R
- Ströhmer R
- Strubig A
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- Sugizaki K
- Sulin Vv
- Sullivan Mj
- Sultan Dms
- Sultanaliyeva L
- Sultansoy S
- Sumida T
- Sun S
- Sun S
- Sunneborn Gudnadottir O
- Sutton Mr
- Svatos M
- Swiatlowski M
- Swirski T
- Sykora I
- Sykora M
- Sykora T
- Ta D
- Tackmann K
- Taffard A
- Tafirout R
- Tafoya Vargas Js
- Taibah Rhm
- Takashima R
- Takeda K
- Takeva Ep
- Takubo Y
- Talby M
- Talyshev Aa
- Tam Kc
- Tamir Nm
- Tanaka A
- Tanaka J
- Tanaka R
- Tanasini M
- Tang J
- Tao Z
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- Tapprogge S
- Tarek Abouelfadl Mohamed A
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- Tassi E
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- Tayalati Y
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- Teixeira De Lima R
- Teixeira-Dias P
- Teoh Jj
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- Terron J
- Terzo S
- Testa M
- Teuscher Rj
- Themistokleous N
- Theveneaux-Pelzer T
- Thielmann O
- Thomas Dw
- Thomas Jp
- Thompson Ea
- Thompson Pd
- Thomson E
- Thorpe Ej
- Tian Y
- Tikhomirov V
- Tikhonov Ya
- Timoshenko S
- Ting Exl
- Tipton P
- Tisserant S
- Tlou Sh
- Tnourji A
- Todome K
- Todorova-Nova S
- Todt S
- Togawa M
- Tojo J
- Tokár S
- Tokushuku K
- Tombs R
- Tomoto M
- Tompkins L
- Tornambe P
- Torrence E
- Torres H
- Torró Pastor E
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- Tosciri C
- Tovey Dr
- Traeet A
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- Trischuk Da
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- Trofymov A
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- Tsiareshka Pv
- Tsirigotis A
- Tsiskaridze V
- Tskhadadze Eg
- Tsopoulou M
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- Tsukerman Ii
- Tsulaia V
- Tsuno S
- Tsur O
- Tsybychev D
- Tu Y
- Tudorache A
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- Tuna An
- Turchikhin S
- Turk Cakir I
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- Tuts Pm
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- Urquijo P
- Usai G
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- Vachon B
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- Valdes Santurio E
- Valente M
- Valentinetti S
- Valero A
- Vallier A
- Valls Ferrer Ja
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- Van Gemmeren P
- Van Stroud S
- Van Vulpen I
- Vanadia M
- Vandelli W
- Vandenbroucke M
- Vandewall Er
- Vannicola D
- Vannoli L
- Vari R
- Varnes Ew
- Varni C
- Varol T
- Varouchas D
- Varriale L
- Varvell Ke
- Vasile Me
- Vaslin L
- Vasquez Ga
- Vazeille F
- Vazquez Furelos D
- Vazquez Schroeder T
- Veatch J
- Vecchio V
- Veen Mj
- Veliscek I
- Veloce Lm
- Veloso F
- Veneziano S
- Ventura A
- Verbytskyi A
- Verducci M
- Vergis C
- Verissimo De Araujo M
- Verkerke W
- Vermeulen Jc
- Vernieri C
- Verschuuren Pj
- Vessella M
- Vesterbacka Ml
- Vetterli Mc
- Vgenopoulos A
- Viaux Maira N
- Vickey Boeriu Oe
- Vickey T
- Viehhauser Gha
- Vigani L
- Villa M
- Villaplana Perez M
- Villhauer Em
- Vilucchi E
- Vincter Mg
- Virdee Gs
- Vishwakarma A
- Vittori C
- Vivarelli I
- Vladimirov V
- Voevodina E
- Vogel F
- Vokac P
- Von Ahnen J
- Von Toerne E
- Vormwald B
- Vorobel V
- Vorobev K
- Vos M
- Vossebeld Jh
- Vozak M
- Vozdecky L
- Vranjes Milosavljevic M
- Vranjes N
- Vreeswijk M
- Vuillermet R
- Vujinovic O
- Vukotic I
- Wada S
- Wagner C
- Wagner W
- Wahdan S
- Wahlberg H
- Wakasa R
- Wakida M
- Walbrecht Vm
- Walder J
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- Walkowiak W
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- Wang Wx
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- Warrack N
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- Weidberg Ar
- Weingarten J
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- Wendland B
- Wengler T
- Wenke Ns
- Wermes N
- Wessels M
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- Wharton Am
- White A
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- Whiteson D
- Wickremasinghe L
- Wiedenmann W
- Wiel C
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- Wieseotte N
- Wiglesworth C
- Wiik-Fuchs Lam
- Wilbern Dj
- Wilkens Hg
- Williams Dm
- Williams Hh
- Williams S
- Willocq S
- Windischhofer Pj
- Winklmeier F
- Winter Bt
- Wittgen M
- Wobisch M
- Wolf A
- Wollrath J
- Wolter Mw
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- Wongel Af
- Worm Sd
- Wosiek Bk
- Woźniak Kw
- Wölker R
- Wraight K
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- Wu X
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- Xiotidis I
- Xu D
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- Yacoob S
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- Yamaguchi Y
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- Yamazaki Y
- Yan J
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- Yang X
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- Yao W
- Yap Yc
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- Ye S
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- Yeletskikh I
- Yexley Mr
- Yin P
- Yorita K
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- Yuan M
- Yuan R
- Yue X
- Zaazoua M
- Zabinski B
- Zaid E
- Zakareishvili T
- Zakharchuk N
- Zambito S
- Zang J
- Zanzi D
- Zaplatilek O
- Zeitnitz C
- Zeißner Sv
- Zeng Jc
- Zenger Dt
- Zenin O
- Zenz S
- Zerradi S
- Zerwas D
- Zhang B
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- Zhang G
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- Zhang X
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- Zhao P
- Zhao T
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- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
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- Zhou N
- Zhou Y
- Zhu C
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- Zhu Hl
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zimine Ni
- Zinsser J
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- Zoccoli A
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- Zorbas Tg
- Zormpa O
- Zou W
- Zwalinski L
- Ženiš T
- Živković L
- Publication venue
- ELSEVIER
- Publication date
- 01/01/2023
- Field of study
- …