506 research outputs found
Allievi interni dell'Istituto di Anatomia umana normale nell'anno accademico 1934-35
Comunicazione da parte di Giuseppe Levi degli studenti che hanno frequentato l'Istituto, tra cui figurano Salvatore Luria, Rita Levi (Montalcini) ed Eugenia Sacerdote. - Formato del documento analogico: 2 c
A network approach for low dimensional signatures from high throughput data
: One of the main objectives of high-throughput genomics studies is to obtain a low-dimensional set of observables-a signature-for sample classification purposes (diagnosis, prognosis, stratification). Biological data, such as gene or protein expression, are commonly characterized by an up/down regulation behavior, for which discriminant-based methods could perform with high accuracy and easy interpretability. To obtain the most out of these methods features selection is even more critical, but it is known to be a NP-hard problem, and thus most feature selection approaches focuses on one feature at the time (k-best, Sequential Feature Selection, recursive feature elimination). We propose DNetPRO, Discriminant Analysis with Network PROcessing, a supervised network-based signature identification method. This method implements a network-based heuristic to generate one or more signatures out of the best performing feature pairs. The algorithm is easily scalable, allowing efficient computing for high number of observables ([Formula: see text]-[Formula: see text]). We show applications on real high-throughput genomic datasets in which our method outperforms existing results, or is compatible with them but with a smaller number of selected features. Moreover, the geometrical simplicity of the resulting class-separation surfaces allows a clearer interpretation of the obtained signatures in comparison to nonlinear classification models
Observation of abundant heat production from a reactor device and of isotopic changes in the fuel
New results are presented from an extended experimental investigation of anomalous heat production in a special type of
reactor tube operating at high temperatures. The reactor, named E-Cat, is charged with a small amount of hydrogen-loaded
nickel powder plus some additives, mainly Lithium. The reaction is primarily initiated by heat from resistor coils around the
reactor tube. Measurements of the radiated power from the reactor were performed with high-resolution thermal imaging
cameras. The measurements of electrical power input were performed with a large bandwidth three-phase power analyzer.
Data were collected during 32 days of running in March 2014. The reactor operating point was set to about 1260 ºC in the
first half of the run, and at about 1400 °C in the second half. The measured energy balance between input and output heat
yielded a COP factor of about 3.2 and 3.6 for the 1260 ºC and 1400 ºC runs, respectively . The total net energy obtained
during the 32 days run was about 1.5 MWh. This amount of energy is far more than can be obtained from any known
chemical sources in the small reactor volume.
A sample of the fuel was carefully examined with respect to its isotopic composition before the run and after the run, using
several standard methods: XPS, EDS, SIMS, ICP-MS and ICP-AES. The isotope composition in Lithium and Nickel was found to agree with the natural composition before the run, while after the run it was found to have changed substantially .
Nuclear reactions are therefore indicated to be present in the run process, which however is hard to reconcile with the fact
that no radioactivity was detected outside the reactor during the run
- …