11,126 research outputs found
Measured descent: A new embedding method for finite metrics
We devise a new embedding technique, which we call measured descent, based on
decomposing a metric space locally, at varying speeds, according to the density
of some probability measure. This provides a refined and unified framework for
the two primary methods of constructing Frechet embeddings for finite metrics,
due to [Bourgain, 1985] and [Rao, 1999]. We prove that any n-point metric space
(X,d) embeds in Hilbert space with distortion O(sqrt{alpha_X log n}), where
alpha_X is a geometric estimate on the decomposability of X. As an immediate
corollary, we obtain an O(sqrt{(log lambda_X) \log n}) distortion embedding,
where \lambda_X is the doubling constant of X. Since \lambda_X\le n, this
result recovers Bourgain's theorem, but when the metric X is, in a sense,
``low-dimensional,'' improved bounds are achieved.
Our embeddings are volume-respecting for subsets of arbitrary size. One
consequence is the existence of (k, O(log n)) volume-respecting embeddings for
all 1 \leq k \leq n, which is the best possible, and answers positively a
question posed by U. Feige. Our techniques are also used to answer positively a
question of Y. Rabinovich, showing that any weighted n-point planar graph
embeds in l_\infty^{O(log n)} with O(1) distortion. The O(log n) bound on the
dimension is optimal, and improves upon the previously known bound of O((log
n)^2).Comment: 17 pages. No figures. Appeared in FOCS '04. To appeaer in Geometric &
Functional Analysis. This version fixes a subtle error in Section 2.
The time-course of colour vision
Four experiments are presented, each investigating temporal properties of colour vision processing in human observers. The first experiment replicates and extends an experiment by Stromeyer et al. (1991). We look for a phase difference between combined temporal modulations in orthogonal directions in colour space, which might null the often-claimed latency of signals originating from the short-wavelength sensitive cones (S-cones). We provide another estimate of the magnitude of this latency, and give evidence to suggest that it originates early in the chromatic pathway, before signals from S-cones are combined with those that receive opposed L- and M-cone input. In the second experiment we adapt observers to two stimuli that are matched in the mean and amplitude of modulation they offer to the cone classes and to the cardinal opponent mechanisms, but that differ in chromatic appearance, and hence their modulation of later colour mechanisms. Chromatic discrimination thresholds after adaptation to these two stimuli differ along intermediate directions in colour space, and we argue that these differences reveal the adaptation response of central colour mechanisms. In the third experiment we demonstrate similar adaptation using the same stimuli, measured with reaction times rather than thresholds. In the final experiment, we measure the degree to which colour constancy is achieved as a function of time in a simulated stimulus environment in which the illuminant changes periodically. We find that perfect constancy is not achieved instantaneously after an illuminant chromaticity shift and that constancy of colour appearance judgements increases over several seconds
Sputtering yield measurements at glancing incidence using a quartz crystal microbalance
Low energy sputtering yields at grazing incidence have been investigated experimentally using a quartz crystal microbalance (QCM) technique. This method involved precoating the QCM with a thin film of the desired target material and relating the resonance frequency shift directly to mass loss during ion bombardment. A highly focused, low divergence ion beam provided a well defined incidence angle. Focusing most of the ion current on the center of the target allowed for higher sensitivity by taking into account the radial mass sensitivity of the QCM. Measurements of Mo, Cu, and W sputtering yields were taken for low energy (80–1000 eV) Xe+ and Ar+ to validate this experimental method. The target films ranged from 3.5 to 8.0 µm in thickness and were deposited so that their crystal structure and density would match those of the bulk material as closely as possible. These properties were characterized using a combination of scanning electron microscope imagery, profilometry, and x-ray diffraction. At normal incidence, the sputtering yields demonstrated satisfactory agreement with previously published work. At angles of incidence up to 40° off normal, the data agreed well with predictions from existing theoretical models. Sputtering yields were found to increase by a factor of 1.6 over this range. The optimum angle for sputtering occurred at 55°, after which the yields rapidly decreased. Measurements were taken up to 80° from the surface normal
A study of the application of computer technology in retail stores
Thesis. 1975. M.S.--Massachusetts Institute of Technology. Alfred P. Sloan School of Management.Bibliography: leaves 134-138.by Robert L. Klimm and James J. Montgomery.M.S
The rational development of molecularly imprinted polymer-based sensors for protein detection.
The detection of specific proteins as biomarkers of disease, health status,
environmental monitoring, food quality, control of fermenters and civil defence
purposes means that biosensors for these targets will become increasingly more
important. Among the technologies used for building specific recognition
properties, molecularly imprinted polymers (MIPs) are attracting much attention.
In this critical review we describe many methods used for imprinting recognition
for protein targets in polymers and their incorporation with a number of
transducer platforms with the aim of identifying the most promising approaches
for the preparation of MIP-based protein sensors (277 references)
Hubble Space Telescope observations of Mars
Hubble Space Telescope (HST) afforded the possibility of resolving features as small as 100 km on the Martian surface even when it is at the far point of its orbit. Therefore it is ideally suited for monitoring seasonal changes on the red planet. The objectives research include: the study of Martian dust storms; use of images obtained through different filters to study the spectral reflectance of regions on the Martian surface; use of ultraviolet images and spectra to measure the amount of ozone in the planet's atmosphere as a function of location of the planet; use of images to study changes in the albedo of the Mars surface; and use of Planetary Camera images to study Martian clouds and to measure the opacity of the atmosphere
Modelling chemistry in the nocturnal boundary layer above tropical rainforest and a generalised effective nocturnal ozone deposition velocity for sub-ppbv NOx conditions
Measurements of atmospheric composition have been made over a remote rainforest landscape. A box model has previously been demonstrated to model the observed daytime chemistry well. However the box model is unable to explain the nocturnal measurements of relatively high [NO] and [O3], but relatively low observed [NO2]. It is shown that a one-dimensional (1-D) column model with simple O3 -NOx chemistry and a simple representation of vertical transport is able to explain the observed nocturnal concentrations and predict the likely vertical profiles of these species in the nocturnal boundary layer (NBL). Concentrations of tracers carried over from the end of the night can affect the atmospheric chemistry of the following day. To ascertain the anomaly introduced by using the box model to represent the NBL, vertically-averaged NBL concentrations at the end of the night are compared between the 1-D model and the box model. It is found that, under low to medium [NOx] conditions (NOx <1 ppbv), a simple parametrisation can be used to modify the box model deposition velocity of ozone, in order to achieve good agreement between the box and 1-D models for these end-of-night concentrations of NOx and O3. This parametrisation would could also be used in global climate-chemistry models with limited vertical resolution near the surface. Box-model results for the following day differ significantly if this effective nocturnal deposition velocity for ozone is implemented; for instance, there is a 9% increase in the following day’s peak ozone concentration. However under medium to high [NOx] conditions (NOx > 1 ppbv), the effect on the chemistry due to the vertical distribution of the species means no box model can adequately represent chemistry in the NBL without modifying reaction rate constants
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Plasma proteome correlates of lipid and lipoprotein: biomarkers of metabolic diversity and inflammation in children of rural Nepal.
Proteins involved in lipoprotein metabolism can modulate cardiovascular health. While often measured to assess adult metabolic diseases, little is known about the proteomes of lipoproteins and their relation to metabolic dysregulation and underlying inflammation in undernourished child populations. The objective of this population study was to globally characterize plasma proteins systemically associated with HDL, LDL, and triglycerides in 500 Nepalese children. Abnormal lipid profiles characterized by elevated plasma triglycerides and low HDL-cholesterol (HDL-C) concentrations were common, especially in children with subclinical inflammation. Among 982 proteins analyzed, the relative abundance of 11, 12, and 52 plasma proteins was correlated with LDL-cholesterol (r = -0.43∼0.70), triglycerides (r = -0.39∼0.53), and HDL-C (r = -0.49∼0.79) concentrations, respectively. These proteins included apolipoproteins and numerous unexpected intracellular and extracellular matrix binding proteins, likely originating in hepatic and peripheral tissues. Relative abundance of two-thirds of the HDL proteome varied with inflammation, with acute phase reactants higher by 4∼40%, and proteins involved in HDL biosynthesis, cholesterol efflux, vitamin transport, angiogenesis, and tissue repair lower by 3∼20%. Untargeted plasma proteomics detects comprehensive sets of both known and novel lipoprotein-associated proteins likely reflecting systemic regulation of lipoprotein metabolism and vascular homeostasis. Inflammation-altered distributions of the HDL proteome may be predisposing undernourished populations to early chronic disease
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