Representation of spectral functions and thermodynamics

In this paper we study the question of effective field assignment to measured or nonperturbatively calculated spectral functions. The straightforward procedure is to approximate it by a sum of independent Breit-Wigner resonances, and assign an independent field to each of these resonances. The problem with this idea is that it introduces new conserved quantities in the free model (the new particle numbers), therefore it changes the symmetry of the system. We avoid this inconsistency by representing each quantum channel with a single effective field, no matter how complicated the spectral function is. Thermodynamical characterization of the system will be computed with this representation method, and its relation to the independent resonance approximation will be discussed.Comment: 15 pages, 9 figures, revtex

Nontrivial eigenvalues of the Liouvillian of an open quantum system

We present methods of finding complex eigenvalues of the Liouvillian of an open quantum system. The goal is to find eigenvalues that cannot be predicted from the eigenvalues of the corresponding Hamiltonian. Our model is a T-type quantum dot with an infinitely long lead. We suggest the existence of the non-trivial eigenvalues of the Liouvillian in two ways: one way is to show that the original problem reduces to the problem of a two-particle Hamiltonian with a two-body interaction and the other way is to show that diagram expansion of the Green's function has correlation between the bra state and the ket state. We also introduce the integral equations equivalent to the original eigenvalue problem.Comment: 5 pages, 2 figures, proceeding

Radar/rain-gauge comparisons on squall lines in Niamey, Niger for the AMMA

Massachusetts Institute of Technology C-band radar observations are integrated with rainfall measurements from an extensive network of gauges in Niamey, Niger, West Africa, for the African Monsoon and Multidisciplinary Analysis (AMMA). The large number of gauges available enabled Z e – R power-law relationships for the convective and stratiform regions of individual squall lines. The Z e – R relationships based solely on radar measurements directly over the gauges were developed for the estimate of rainfall and attendant latent heat release (by other AMMA investigators) where gauges were unavailable. The low prefactor values of the Z e – R power laws relative to like values for Z – R disdrometer power laws have contributions of order 1–2 dB from the use of the lowest beam tilt (0.57° ) and ∼1–2 dB by the radar reading low. (The sphere calibration and the Tropical Rainfall Measuring Mission TRMM—radar calibration are inconsistent at the 1–2 dB level for unknown reasons.) Radar/gauge comparisons are also shown for individual storms. Accurate, unbiased results for the convective regime require adjustment of the radar-to-gauge radials for attenuation. Beam filling problems and aliasing issues can often be identified in the case of outlier points. Copyright © 2010 Royal Meteorological SocietyPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69205/1/548_ftp.pd

Transport properties of dense fluid argon

We calculate using molecular dynamics simulations the transport properties of realistically modeled fluid argon at pressures up to $\simeq 50GPa$ and temperatures up to $3000K$. In this context we provide a critique of some newer theoretical predictions for the diffusion coefficients of liquids and a discussion of the Enskog theory relevance under two different adaptations: modified Enskog theory (MET) and effective diameter Enskog theory. We also analyze a number of experimental data for the thermal conductivity of monoatomic and small diatomic dense fluids.Comment: 8 pages, 6 figure

Strongly correlating liquids and their isomorphs

This paper summarizes the properties of strongly correlating liquids, i.e., liquids with strong correlations between virial and potential energy equilibrium fluctuations at constant volume. We proceed to focus on the experimental predictions for strongly correlating glass-forming liquids. These predictions include i) density scaling, ii) isochronal superposition, iii) that there is a single function from which all frequency-dependent viscoelastic response functions may be calculated, iv) that strongly correlating liquids are approximately single-parameter liquids with close to unity Prigogine-Defay ratio, and v) that the fictive temperature initially decreases for an isobaric temperature up jump. The "isomorph filter", which allows one to test for universality of theories for the non-Arrhenius temperature dependence of the relaxation time, is also briefly discussed

Spatio-temporal variability of warm rain events over southern West Africa from geostationary satellite observations for climate monitoring and model evaluation

This paper presents the spatiotemporal variability of warm rain events over southern West Africa (SWA) during the summer monsoon season for the first time, using Spinning Enhanced Visible Infrared Radiometer (SEVIRI) observations on the Meteosat geostationary satellites. The delineation of warm rain events is based on the principle that precipitating low-level clouds are associated with either sufficient water content or large cloud droplet size. Capitalising on the ability of spaceborne radar to resolve vertical cloud structures and detect the presence of precipitation, the delineation is trained by collocated SEVIRI and CloudSat observations. The resulting 12-years of observations from SEVIRI are used to examine the spatial, diurnal, seasonal and interannual variability of warm rain events over SWA. Warm rain events predominate during the monsoon in August, with little interannual variability, and persist over orography in the morning and the coasts after midday, likely enhanced by orographic lifting and land-sea breeze effects. Warm clouds have a much higher probability of precipitation along the coastlines of Liberia and Nigeria compared to the central SWA coastline and further inland. Finally, when evaluating an 8-day yet high-spatial resolution model simulation, we find that warm rain frequencies from the simulation agree well with SEVIRI near the coast but simulated warm cloud cover and thus warm rain frequencies are too low over the Gulf of Guinea. The probability of precipitation of warm clouds is also too low inland. The newly developed climatology creates opportunities to further investigate the diurnal cycle of warm rain, study aerosol-cloud-precipitation interactions, and assess the role of warm rain in the water cycle across Africa and beyond

Multi-level evidence of an allelic hierarchy of USH2A variants in hearing, auditory processing and speech/language outcomes.

Language development builds upon a complex network of interacting subservient systems. It therefore follows that variations in, and subclinical disruptions of, these systems may have secondary effects on emergent language. In this paper, we consider the relationship between genetic variants, hearing, auditory processing and language development. We employ whole genome sequencing in a discovery family to target association and gene x environment interaction analyses in two large population cohorts; the Avon Longitudinal Study of Parents and Children (ALSPAC) and UK10K. These investigations indicate that USH2A variants are associated with altered low-frequency sound perception which, in turn, increases the risk of developmental language disorder. We further show that Ush2a heterozygote mice have low-level hearing impairments, persistent higher-order acoustic processing deficits and altered vocalizations. These findings provide new insights into the complexity of genetic mechanisms serving language development and disorders and the relationships between developmental auditory and neural systems

YWHAE loss of function causes a rare neurodevelopmental disease with brain abnormalities in human and mouse.

Miller-Dieker syndrome is caused by a multiple gene deletion, including PAFAH1B1 and YWHAE. Although deletion of PAFAH1B1 causes lissencephaly unambiguously, deletion of YWHAE alone has not clearly been linked to a human disorder. Cases with YWHAE variants were collected through international data sharing networks. To address the specific impact of YWHAE loss of function, we phenotyped a mouse knockout of Ywhae. We report a series of 10 individuals with heterozygous loss-of-function YWHAE variants (3 single-nucleotide variants and 7 deletions <1 Mb encompassing YWHAE but not PAFAH1B1), including 8 new cases and 2 follow-ups, added with 5 cases (copy number variants) from literature review. Although, until now, only 1 intragenic deletion has been described in YWHAE, we report 4 new variants specifically in YWHAE (3 splice variants and 1 intragenic deletion). The most frequent manifestations are developmental delay, delayed speech, seizures, and brain malformations, including corpus callosum hypoplasia, delayed myelination, and ventricular dilatation. Individuals with variants affecting YWHAE alone have milder features than those with larger deletions. Neuroanatomical studies in Ywhae <sup>-/-</sup> mice revealed brain structural defects, including thin cerebral cortex, corpus callosum dysgenesis, and hydrocephalus paralleling those seen in humans. This study further demonstrates that YWHAE loss-of-function variants cause a neurodevelopmental disease with brain abnormalities